The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons

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The docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.E05-12-1122
P932PMC publication ID1483050
P698PubMed publication ID16687575

P2093author name stringTeiichi Furuichi
Ryuichi Sakai
Jinhong Huang
P2860cites workActivation of Rac1 by a Crk SH3-binding protein, DOCK180Q22007972
Integrin signalling: a new Cas(t) of characters enters the stageQ22253193
BPAG1n4 is essential for retrograde axonal transport in sensory neuronsQ24298566
CAS/Crk coupling serves as a "molecular switch" for induction of cell migrationQ24311510
A novel signaling molecule, p130, forms stable complexes in vivo with v-Crk and v-Src in a tyrosine phosphorylation-dependent mannerQ24318312
Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migrationQ24318859
A direct interaction between JNK1 and CrkII is critical for Rac1-induced JNK activationQ24535521
Cellular motility driven by assembly and disassembly of actin filamentsQ27860676
SH2 domains recognize specific phosphopeptide sequencesQ27860748
JNK1 Is Required for Maintenance of Neuronal Microtubules and Controls Phosphorylation of Microtubule-Associated ProteinsQ28190244
Cytoskeletal Dynamics and Transport in Growth Cone Motility and Axon GuidanceQ28209458
Domain-specific function of ShcC docking protein in neuroblastoma cellsQ28237149
Recruitment of Pyk2 and Cbl to lipid rafts mediates signals important for actin reorganization in growing neuritesQ28260417
Direct binding of C-terminal region of p130Cas to SH2 and SH3 domains of Src kinaseQ28277700
Cardiovascular anomaly, impaired actin bundling and resistance to Src-induced transformation in mice lacking p130CasQ28279024
Constitutively active cytoplasmic c-Jun N-terminal kinase 1 is a dominant regulator of dendritic architecture: role of microtubule-associated protein 2 as an effectorQ28512127
Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrateQ28567205
Nerve growth factor stimulates the tyrosine phosphorylation of endogenous Crk-II and augments its association with p130Cas in PC-12 cellsQ28574772
SRC binding to the cytoskeleton, triggered by growth cone attachment to laminin, is protein tyrosine phosphatase-dependentQ28578043
Control of axonal branching and synapse formation by focal adhesion kinaseQ28587436
Cupidin, an isoform of Homer/Vesl, interacts with the actin cytoskeleton and activated rho family small GTPases and is expressed in developing mouse cerebellar granule cellsQ28590952
Rho GTPases in growth cone guidanceQ28647606
Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactionsQ30168137
Downstream of Crk adaptor signaling pathway: activation of Jun kinase by v-Crk through the guanine nucleotide exchange protein C3G.Q30176600
Mechanisms of CAS substrate domain tyrosine phosphorylation by FAK and SrcQ30453539
Migration of nerve growth cones requires detergent-resistant membranes in a spatially defined and substrate-dependent manner.Q30720712
pp60c-src expression in the developing rat brainQ33573046
c-src gene product in developing rat brain is enriched in nerve growth cone membranesQ33631204
From the growth cone surface to the cytoskeleton: one journey, many pathsQ33996759
Mechanisms of Neural Patterning and Specification in the Development CerebellumQ34299482
Actin cytoskeleton regulation in neuronal morphogenesis and structural plasticityQ34762533
New insights into the diversity and function of neuronal immunoglobulin superfamily moleculesQ35071009
NCAM-dependent neurite outgrowth is inhibited in neurons from Fyn-minus miceQ36234811
Overlapping functions of the cell adhesion molecules Nr-CAM and L1 in cerebellar granule cell developmentQ36294022
Regulated tyrosine phosphorylation at the tips of growth cone filopodiaQ36383181
pp60c-src in the developing cerebellumQ36490812
Expression of the yes proto-oncogene in cerebellar Purkinje cellsQ36762908
Filopodia and growth cones in the vertically migrating granule cells of the postnatal mouse cerebellumQ36893721
Tyrosine phosphorylation of paxillin affects the metastatic potential of human osteosarcomaQ40426949
Making the connection: Cytoskeletal rearrangements during growth cone guidanceQ40430559
Differential contributions of Ng-CAM and N-CAM to cell adhesion in different neural regionsQ41484527
Neural cell adhesion molecules of the immunoglobulin superfamily: role in axon growth and guidanceQ41689383
Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons.Q41830984
Isolation and characterization of detergent-resistant microdomains responsive to NCAM-mediated signaling from growth conesQ43870915
PKC signaling mediates global enhancement of excitatory synaptogenesis in neurons triggered by local contact with astrocytesQ44758004
Impaired neurite outgrowth of src-minus cerebellar neurons on the cell adhesion molecule L1.Q48153530
Localization of p62c-yes protein in mammalian neural tissuesQ48642799
Nerve growth cones isolated from fetal rat brain: subcellular fractionation and characterizationQ48708617
L1 mono- and polyclonal antibodies modify cell migration in early postnatal mouse cerebellumQ48739074
The Lck tyrosine kinase is expressed in brain neuronsQ48909981
Development of polarity in cerebellar granule neurons.Q52196570
Transient expression of lyn gene in Purkinje cells during cerebellar development.Q52201940
Differential developmental expression of cellular yes and cellular src proteins in cerebellum.Q52251908
NCAM140 interacts with the focal adhesion kinase p125(fak) and the SRC-related tyrosine kinase p59(fyn)Q73174566
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P1104number of pages10
P304page(s)3187-3196
P577publication date2006-05-10
P1433published inMolecular Biology of the CellQ2338259
P1476titleThe docking protein Cas links tyrosine phosphorylation signaling to elongation of cerebellar granule cell axons
P478volume17

Reverse relations

cites work (P2860)
Q37705008Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling
Q26253940Cerebellar development transcriptome database (CDT-DB): Profiling of spatio-temporal gene expression during the postnatal development of mouse cerebellum
Q33302060Developmental expression and differentiation-related neuron-specific splicing of metastasis suppressor 1 (Mtss1) in normal and transformed cerebellar cells
Q37399985Developmentally regulated Ca2+-dependent activator protein for secretion 2 (CAPS2) is involved in BDNF secretion and is associated with autism susceptibility.
Q28727027Ethanol disrupts axon outgrowth stimulated by netrin-1, GDNF, and L1 by blocking their convergent activation of Src family kinase signaling
Q28579317Ethanol inhibits neuronal differentiation by disrupting activity-dependent neuroprotective protein signaling
Q39984335Expression and tyrosine phosphorylation of Crk-associated substrate lymphocyte type (Cas-L) protein in human neutrophils
Q28512703Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth--structure and function of the second kinase noncatalytic C-lobe domain
Q30525348Netrin-1 attracts axons through FAK-dependent mechanotransduction
Q39870863Neurogenesis-related genes expression profiling of mouse fibroblastic stem cells induced by Wnt signaling
Q35107289Oligodendroglial p130Cas is a target of Fyn kinase involved in process formation, cell migration and survival
Q28505219Opalin, a transmembrane sialylglycoprotein located in the central nervous system myelin paranodal loop membrane
Q30560971Profiling, Bioinformatic, and Functional Data on the Developing Olfactory/GnRH System Reveal Cellular and Molecular Pathways Essential for This Process and Potentially Relevant for the Kallmann Syndrome.
Q34979113Spatial phosphoprotein profiling reveals a compartmentalized extracellular signal-regulated kinase switch governing neurite growth and retraction
Q37829666Systematizing and cloning of genes involved in the cerebellar cortex circuit development.
Q47381761Temporal analysis of hippocampal CA3 gene co-expression networks in a rat model of febrile seizures
Q36119357The EphA4 receptor regulates dendritic spine remodeling by affecting beta1-integrin signaling pathways
Q30156800The SH2 domain protein Shep1 regulates the in vivo signaling function of the scaffolding protein Cas
Q42645262The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain.
Q46082553The effects of blood pressure and urokinase on brain injuries after experimental cerebral infarction in rats
Q28505034Very-KIND, a KIND domain containing RasGEF, controls dendrite growth by linking Ras small GTPases and MAP2

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