Ewing sarcoma

scientific article published in July 2018

Ewing sarcoma is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/S41572-018-0003-X
P698PubMed publication ID29977059

P50authorOlivier DelattreQ30119391
Heinrich KovarQ41462089
P2093author name stringUta Dirksen
Didier Surdez
Poul H. Sorensen
Enrique de Álava
Thomas G. P. Grünewald
Florencia Cidre-Aranaz
Eleni M. Tomazou
P2860cites workChimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatelliteQ22122062
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumoursQ24298221
JHDM2A, a JmjC-containing H3K9 demethylase, facilitates transcription activation by androgen receptorQ24315882
A new member of the ETS family fused to EWS in Ewing tumorsQ24317176
MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cellsQ24320635
Condensin and cohesin complexity: the expanding repertoire of functionsQ24617076
Phase I trial of "bi-shRNAi(furin)/GMCSF DNA/autologous tumor cell" vaccine (FANG) in advanced cancerQ24625197
CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesisQ24642797
BMI-1 promotes ewing sarcoma tumorigenicity independent of CDKN2A repressionQ24650619
Therapeutic opportunities in Ewing sarcoma: EWS-FLI inhibition via LSD1 targetingQ26768602
Targeting EZH2 in cancerQ26769027
The second European interdisciplinary Ewing sarcoma research summit--A joint effort to deconstructing the multiple layers of a complex diseaseQ26775306
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomicsQ26776098
Preclinical Childhood Sarcoma Models: Drug Efficacy Biomarker Identification and ValidationQ26784048
Novel uses of immunohistochemistry in the diagnosis and classification of soft tissue tumorsQ27001114
MicroRNA-34a: a potential therapeutic target in human cancerQ27003249
Ewing sarcoma cells secrete EWS/Fli-1 fusion mRNA via microvesiclesQ27303905
EWS-FLI1 fusion transcript structure is an independent determinant of prognosis in Ewing's sarcomaQ27851507
The genomic landscape of pediatric Ewing sarcomaQ27853063
High-dose therapy for patients with primary multifocal and early relapsed Ewing's tumors: results of two consecutive regimens assessing the role of total-body irradiationQ28201421
The NFATc2 gene is involved in a novel cloned translocation in a Ewing sarcoma variant that couples its function in immunology to oncologyQ28239202
The mechanisms behind the therapeutic activity of BET bromodomain inhibitionQ28241504
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERGQ28252253
Histone methylation: a dynamic mark in health, disease and inheritanceQ28263573
G-Protein coupled receptor 64 promotes invasiveness and metastasis in Ewing sarcomas through PGF and MMP1Q28283859
Racial differences in the incidence of mesenchymal tumors associated with EWSR1 translocationQ28302617
Chromatin crosstalk in development and disease: lessons from RESTQ28306534
Dynamic histone H3 methylation during gene induction: HYPB/Setd2 mediates all H3K36 trimethylationQ28593817
Caveolin-1 promotes Ewing sarcoma metastasis regulating MMP-9 expression through MAPK/ERK pathwayQ28816968
Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcomaQ29028729
Receptor tyrosine kinase gene expression profiles of Ewing sarcomas reveal ROR1 as a potential therapeutic target in metastatic diseaseQ30315828
YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1.Q30635379
Realizing the promise of cancer predisposition genesQ30743260
Phase 1 trial of temsirolimus in combination with irinotecan and temozolomide in children, adolescents and young adults with relapsed or refractory solid tumors: a Children's Oncology Group StudyQ33411585
Cyclophosphamide compared with ifosfamide in consolidation treatment of standard-risk Ewing sarcoma: results of the randomized noninferiority Euro-EWING99-R1 trialQ33416199
The oncogenic EWS-FLI1 protein binds in vivo GGAA microsatellite sequences with potential transcriptional activation functionQ33420364
Phase I trial of a novel anti-GD2 monoclonal antibody, Hu14.18K322A, designed to decrease toxicity in children with refractory or recurrent neuroblastomaQ33597441
Flow cytometric detection of Ewing sarcoma cells in peripheral blood and bone marrowQ33758219
New strategies in ewing sarcoma: lost in translation?Q33758471
Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse modelQ33798299
What is the impact of local control in Ewing sarcoma: analysis of the first Brazilian collaborative study group - EWING1Q33805175
Ewing's sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitorsQ33808340
Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology GroupQ33813608
The genomic landscape of the Ewing Sarcoma family of tumors reveals recurrent STAG2 mutationQ33881163
Modeling initiation of Ewing sarcoma in human neural crest cellsQ33894979
Hypoxia modulates EWS-FLI1 transcriptional signature and enhances the malignant properties of Ewing's sarcoma cells in vitroQ33908885
Development of Ewing's sarcoma from primary bone marrow-derived mesenchymal progenitor cellsQ33992270
Safety assessment of intensive induction with vincristine, ifosfamide, doxorubicin, and etoposide (VIDE) in the treatment of Ewing tumors in the EURO-E.W.I.N.G. 99 clinical trialQ33994512
ZEB2 Represses the Epithelial Phenotype and Facilitates Metastasis in Ewing SarcomaQ37424383
BET bromodomain inhibitors suppress EWS-FLI1-dependent transcription and the IGF1 autocrine mechanism in Ewing sarcomaQ37536618
Non-coding RNAs as direct and indirect modulators of epigenetic regulationQ37591537
Widespread Chromatin Accessibility at Repetitive Elements Links Stem Cells with Human CancerQ37608149
Ganglioside GD2 as a therapeutic target for antibody-mediated therapy in patients with osteosarcoma.Q37624276
SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functionsQ37625383
EWS-FLI-1 regulates the neuronal repressor gene REST, which controls Ewing sarcoma growth and vascular morphologyQ37672300
CD99 polymorphisms significantly influence the probability to develop Ewing sarcoma in earlier age and patient disease progressionQ37718471
Utility of bone marrow aspiration and biopsy in initial staging of Ewing sarcomaQ38244942
Stress-mediated translational control in cancer cellsQ38281204
A transcriptional profiling meta-analysis reveals a core EWS-FLI gene expression signatureQ38293763
Hsa-mir-145 is the top EWS-FLI1-repressed microRNA involved in a positive feedback loop in Ewing's sarcomaQ38338166
DNA methylation heterogeneity defines a disease spectrum in Ewing sarcoma.Q38373823
Beta-platelet-derived growth factor receptor mediates motility and growth of Ewing's sarcoma cells.Q38452580
EWS/FLI1 Target Genes and Therapeutic Opportunities in Ewing Sarcoma.Q38563638
Ewing Sarcoma: Current Management and Future Approaches Through CollaborationQ38573422
Role for the EWS domain of EWS/FLI in binding GGAA-microsatellites required for Ewing sarcoma anchorage independent growthQ38605150
Update on Families of Round Cell Sarcomas Other than Classical Ewing Sarcomas.Q38630100
Regulation of gene transcription by Polycomb proteinsQ38668767
EWS-FLI1 perturbs MRTFB/YAP-1/TEAD target gene regulation inhibiting cytoskeletal autoregulatory feedback in Ewing sarcomaQ38696838
Quality of Survivorship in a Rare Disease: Clinicofunctional Outcome and Physical Activity in an Observational Cohort Study of 618 Long-Term Survivors of Ewing Sarcoma.Q38738129
Micro-Environmental Stress Induces Src-Dependent Activation of Invadopodia and Cell Migration in Ewing SarcomaQ38749818
Activation of Wnt/β-Catenin in Ewing Sarcoma Cells Antagonizes EWS/ETS Function and Promotes Phenotypic Transition to More Metastatic Cell StatesQ38760598
PARP Inhibitors Sensitize Ewing Sarcoma Cells to Temozolomide-Induced Apoptosis via the Mitochondrial PathwayQ38830175
Suppression of deacetylase SIRT1 mediates tumor-suppressive NOTCH response and offers a novel treatment option in metastatic Ewing sarcomaQ38950669
Reversible LSD1 inhibition interferes with global EWS/ETS transcriptional activity and impedes Ewing sarcoma tumor growth.Q38981458
Stress-induced CXCR4 promotes migration and invasion of ewing sarcomaQ39013447
The Zyxin-related protein thyroid receptor interacting protein 6 (TRIP6) is overexpressed in Ewing's sarcoma and promotes migration, invasion and cell growthQ39096397
First identification of Ewing's sarcoma-derived extracellular vesicles and exploration of their biological and potential diagnostic implications.Q39177112
DKK2 mediates osteolysis, invasiveness, and metastatic spread in Ewing sarcomaQ39233911
Mechanism and relevance of EWS/FLI-mediated transcriptional repression in Ewing sarcomaQ39239580
A TARBP2-dependent miRNA expression profile underlies cancer stem cell properties and provides candidate therapeutic reagents in Ewing sarcomaQ39331421
A new subtype of bone sarcoma defined by BCOR-CCNB3 gene fusionQ39386166
Tumor-specific retargeting of an oncogenic transcription factor chimera results in dysregulation of chromatin and transcription.Q39442604
Germline Mutations in Predisposition Genes in Pediatric CancerQ36524309
Recent advances in the molecular pathogenesis of Ewing's sarcomaQ36562720
Genomic EWS-FLI1 fusion sequences in Ewing sarcoma resemble breakpoint characteristics of immature lymphoid malignanciesQ36618540
Prognostic impact of chromosomal aberrations in Ewing tumoursQ36644524
MicroRNAs in Ewing SarcomaQ36722134
Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcomaQ36738866
Pilot Trial of FANG Immunotherapy in Ewing's SarcomaQ36756669
Microsatellites as EWS/FLI response elements in Ewing's sarcomaQ36786777
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.Q36892577
Recapitulating the Size and Cargo of Tumor Exosomes in a Tissue-Engineered ModelQ36970355
ERBB4 confers metastatic capacity in Ewing sarcomaQ37040838
EWS-FLI1 suppresses NOTCH-activated p53 in Ewing's sarcomaQ37135628
Ewing sarcoma with ERG gene rearrangements: A molecular study focusing on the prevalence of FUS-ERG and common pitfalls in detecting EWSR1-ERG fusions by FISHQ37222239
Oncogenic ETS fusions deregulate E2F3 target genes in Ewing sarcoma and prostate cancerQ37272420
A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcomaQ37421771
Mesenchymal stem cell features of Ewing tumorsQ34003979
Basic fibroblast growth factor in the bone microenvironment enhances cell motility and invasion of Ewing's sarcoma family of tumours by activating the FGFR1-PI3K-Rac1 pathwayQ34059738
Emergent Properties of EWS/FLI Regulation via GGAA Microsatellites in Ewing's SarcomaQ34109415
Cancer biology and NuRD: a multifaceted chromatin remodelling complexQ34148512
Molecular dissection of the mechanism by which EWS/FLI expression compromises actin cytoskeletal integrity and cell adhesion in Ewing sarcomaQ34166817
Long-term survivors of childhood Ewing sarcoma: report from the childhood cancer survivor studyQ34169663
EWS-FLI1 induces developmental abnormalities and accelerates sarcoma formation in a transgenic mouse modelQ34206278
Epigenome mapping reveals distinct modes of gene regulation and widespread enhancer reprogramming by the oncogenic fusion protein EWS-FLI1.Q34464009
A phase II study of clinical activity of SCH 717454 (robatumumab) in patients with relapsed osteosarcoma and Ewing sarcomaQ34532397
Fractures in pediatric Ewing sarcomaQ34569697
Late effects of chemotherapy and radiotherapy in osteosarcoma and Ewing sarcoma patients: the Italian Sarcoma Group Experience (1983-2006).Q34636631
Sarcoma classification: an update based on the 2013 World Health Organization Classification of Tumors of Soft Tissue and BoneQ34660467
Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutationsQ34691553
Bone marrow cells participate in tumor vessel formation that supports the growth of Ewing's sarcoma in the lungQ34928239
EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiationQ34963463
Comparative evaluation of local control strategies in localized Ewing sarcoma of bone: a report from the Children's Oncology Group.Q35007934
Specific sites in the C terminus of CTCF interact with the SA2 subunit of the cohesin complex and are required for cohesin-dependent insulation activityQ35096316
Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesisQ35145374
Macrophage infiltration predicts a poor prognosis for human ewing sarcomaQ35168030
Promiscuous partnerships in Ewing's sarcomaQ35188770
Targeting the DNA repair pathway in Ewing sarcomaQ35283099
Preliminary efficacy of the anti-insulin-like growth factor type 1 receptor antibody figitumumab in patients with refractory Ewing sarcomaQ35609719
A zebrafish transgenic model of Ewing's sarcoma reveals conserved mediators of EWS-FLI1 tumorigenesisQ35665048
Gene Expression Profiling of Ewing Sarcoma Tumors Reveals the Prognostic Importance of Tumor-Stromal Interactions: A Report from the Children's Oncology GroupQ35688154
IL6 secreted by Ewing sarcoma tumor microenvironment confers anti-apoptotic and cell-disseminating paracrine responses in Ewing sarcoma cellsQ35717574
High neuropeptide Y release associates with Ewing sarcoma bone dissemination - in vivo model of site-specific metastasesQ35740170
EWS-FLI1 utilizes divergent chromatin remodeling mechanisms to directly activate or repress enhancer elements in Ewing sarcomaQ35820934
The ganglioside antigen G(D2) is surface-expressed in Ewing sarcoma and allows for MHC-independent immune targetingQ35832365
Mutational inactivation of STAG2 causes aneuploidy in human cancerQ36029045
EWS-FLI-1-targeted cytotoxic T-cell killing of multiple tumor types belonging to the Ewing sarcoma family of tumorsQ36295912
The PARP inhibitor olaparib enhances the sensitivity of Ewing sarcoma to trabectedinQ36326279
Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.Q36374350
Randomized controlled trial of interval-compressed chemotherapy for the treatment of localized Ewing sarcoma: a report from the Children's Oncology GroupQ36389207
A Retrospective Multicentric Study of Ewing Sarcoma Family of Tumors in Patients Older Than 50: Management and Outcome.Q47149930
CD99 at the crossroads of physiology and pathologyQ47203268
Orthotopic patient-derived xenografts of paediatric solid tumoursQ47565470
Expression of the EWS/FLI-1 oncogene in murine primary bone-derived cells Results in EWS/FLI-1-dependent, ewing sarcoma-like tumorsQ47605320
Inhibition of the oncogenic fusion protein EWS-FLI1 causes G2-M cell cycle arrest and enhanced vincristine sensitivity in Ewing's sarcoma.Q47703632
Programmed cell death ligand 1 (PD-L1) expression is not a predominant feature in Ewing sarcomas.Q47861303
Cancer-Specific Retargeting of BAF Complexes by a Prion-like Domain.Q47899647
Molecular analysis of Ewing's sarcoma: another fusion gene, EWS-E1AF, available for diagnosisQ48022580
Phase 1 trial of ontuxizumab (MORAb-004) in children with relapsed or refractory solid tumors: A report from the Children's Oncology Group Phase 1 Pilot Consortium (ADVL1213).Q48324213
Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targetsQ49166444
Can FDG-PET/CT replace blind bone marrow biopsy of the posterior iliac crest in Ewing sarcoma?Q49199745
PRDM9 and Its Role in Genetic RecombinationQ49796112
Rhabdomyosarcoma, Ewing Sarcoma, and Other Round Cell SarcomasQ50004172
Sarcomas With CIC-rearrangements Are a Distinct Pathologic Entity With Aggressive Outcome: A Clinicopathologic and Molecular Study of 115 CasesQ50182020
Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.Q50784397
Epithelial-to-Mesenchymal and Mesenchymal-to-Epithelial Transition in Mesenchymal Tumors: A Paradox in Sarcomas?Q51807220
Review with novel markers facilitates precise categorization of 41 cases of diagnostically challenging, "undifferentiated small round cell tumors". A clinicopathologic, immunophenotypic and molecular analysis.Q52584817
Farm exposures, parental occupation, and risk of Ewing's sarcoma in Australia: a national case-control study.Q52596389
CD99: A Cell Surface Protein with an Oncojanus Role in Tumors.Q52658031
Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?Q52685529
Ploidy and karyotype complexity are powerful prognostic indicators in the Ewing's sarcoma family of tumors: a study by the United Kingdom Cancer Cytogenetics and the Children's Cancer and Leukaemia Group.Q52852427
Molecular diagnosis of Ewing sarcoma family of tumors: a comparative analysis of 560 cases with FISH and RT-PCR.Q53061514
Significant benefit of multimodal imaging: PET/CT compared with PET alone in staging and follow-up of patients with Ewing tumors.Q53453257
EWS-FLI-1 expression triggers a Ewing's sarcoma initiation program in primary human mesenchymal stem cells.Q53487773
Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells.Q54105269
EWS-FLI1 and EWS-ERG gene fusions are associated with similar clinical phenotypes in Ewing's sarcoma.Q54158232
A phase 2 trial of R1507, a monoclonal antibody to the insulin-like growth factor-1 receptor (IGF-1R), in patients with recurrent or refractory rhabdomyosarcoma, osteosarcoma, synovial sarcoma, and other soft tissue sarcomas: results of a Sarcoma AlQ54355019
Pro-inflammatory chemokine-chemokine receptor interactions within the Ewing sarcoma microenvironment determine CD8(+) T-lymphocyte infiltration and affect tumour progression.Q54396439
Increased risk of systemic relapses associated with bone marrow micrometastasis and circulating tumor cells in localized ewing tumor.Q54797647
Nonmetastatic Ewing family tumors: high-dose chemotherapy with stem cell rescue in poor responder patients. Results of the Italian Sarcoma Group/Scandinavian Sarcoma Group III protocolQ56985814
Bone sarcomas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-upQ57570627
MIC2 is a specific marker for ewing's sarcoma and peripheral primitive neuroectodermal tumors. Evidence for a common histogenesis of ewing's sarcoma and peripheral primitive neuroectodermal tumors from MIC2 expression and specific chromosome aberratiQ57756690
EWS-FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma.Q59061840
CIC-DUX4fusion-positive round-cell sarcomas of soft tissue and bone: a single-institution morphological and molecular analysis of seven casesQ60628298
Primary metastatic Ewing's family tumors: results of the Italian Sarcoma Group and Scandinavian Sarcoma Group ISG/SSG IV Study including myeloablative chemotherapy and total-lung irradiationQ60628603
Chromosomes in Ewing's sarcoma. II. Nonrandom additional changes, trisomy 8 and der(16)t(1;16)Q67920396
[The German Society of Pediatric Oncology Cooperative Ewing Sarcoma Studies CESS 81/86: report after 6 1/2 years]Q70416686
Translocation involving chromosome 22 in Ewing's sarcoma. A cytogenetic study of four fresh tumorsQ71321688
Initial symptoms and clinical features in osteosarcoma and Ewing sarcomaQ73810170
A link between basic fibroblast growth factor (bFGF) and EWS/FLI-1 in Ewing's sarcoma cellsQ74298025
Ewing's tumors with primary lung metastases: survival analysis of 114 (European Intergroup) Cooperative Ewing's Sarcoma Studies patientsQ77302606
Definitive radiotherapy for ewing tumors of extremities and pelvis: long-term disease control, limb function, and treatment toxicityQ81211245
Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cellsQ81546174
Intercellular junctions in Ewing sarcoma/primitive neuroectodermal tumor: additional evidence of epithelial differentiationQ81791441
Risk of recurrence and survival after relapse in patients with Ewing sarcomaQ83731173
Ewing sarcoma demonstrates racial disparities in incidence-related and sex-related differences in outcome: an analysis of 1631 cases from the SEER database, 1973-2005Q84110858
Histological heterogeneity of Ewing's sarcoma/PNET: an immunohistochemical analysis of 415 genetically confirmed cases with clinical supportQ84750681
The value of local treatment in patients with primary, disseminated, multifocal Ewing sarcoma (PDMES)Q84928460
Time to diagnosis of ewing tumors in children and adolescents is not associated with metastasis or survivalQ85939579
Carboplatin in the treatment of Ewing sarcoma: Results of the first Brazilian collaborative study group for Ewing sarcoma family tumors-EWING1Q87198365
Age dependency of primary tumor sites and metastases in patients with Ewing sarcomaQ88948561
STEAP1 is associated with the invasive and oxidative stress phenotype of Ewing tumorsQ39443702
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancyQ39465507
1q gain and CDT2 overexpression underlie an aggressive and highly proliferative form of Ewing sarcomaQ39493814
Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot studyQ39538403
EWS-FLI1-mediated suppression of the RAS-antagonist Sprouty 1 (SPRY1) confers aggressiveness to Ewing sarcoma.Q39634845
Zoledronic acid as a new adjuvant therapeutic strategy for Ewing's sarcoma patientsQ39655936
EWS-FLI-1 modulates miRNA145 and SOX2 expression to initiate mesenchymal stem cell reprogramming toward Ewing sarcoma cancer stem cellsQ39716224
Reduced human leukocyte antigen expression in advanced-stage Ewing sarcoma: implications for immune recognitionQ39875012
Preclinical evaluation of the antineoplastic action of 5-aza-2'-deoxycytidine and different histone deacetylase inhibitors on human Ewing's sarcoma cellsQ39915669
No improvement of survival with reduced- versus high-intensity conditioning for allogeneic stem cell transplants in Ewing tumor patientsQ39967014
Adjuvant Immunotherapy to Improve Outcome in High-Risk Pediatric SarcomasQ40045147
Molecular Screening for Cancer Treatment Optimization (MOSCATO-01) in Pediatric Patients: A Single-Institutional Prospective Molecular Stratification TrialQ40112795
Chromosome 9p21 gene copy number and prognostic significance of p16 in ESFT.Q40126904
Histone deacetylase inhibitors induce cell death and enhance the apoptosis-inducing activity of TRAIL in Ewing's sarcoma cellsQ40135808
A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP.Q40155430
Ewing's sarcoma in female siblings. A clinical report and review of the literatureQ40238817
Genomic EWSR1 Fusion Sequence as Highly Sensitive and Dynamic Plasma Tumor Marker in Ewing Sarcoma.Q40381404
Impact of high-dose busulfan plus melphalan as consolidation in metastatic Ewing tumors: a study by the Société Française des Cancers de l'Enfant.Q40471939
DNA microarrays reveal relationship of Ewing family tumors to both endothelial and fetal neural crest-derived cells and define novel targetsQ40490707
Impact of IGF-I/IGF-IR circuit on the angiogenetic properties of Ewing's sarcoma cellsQ40601528
Can postoperative radiotherapy be omitted in localised standard-risk Ewing sarcoma? An observational study of the Euro-E.W.I.N.G groupQ40755680
Local control in Ewing sarcoma of the chest wall: results of the EURO-EWING 99 trial.Q40806118
Combinatorial generation of variable fusion proteins in the Ewing family of tumours.Q40874946
Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoproteinQ40925366
Translational Activation of HIF1α by YB-1 Promotes Sarcoma MetastasisQ40948678
The insulin-like growth factor-I receptor is required for EWS/FLI-1 transformation of fibroblastsQ41072490
The histone demethylase KDM3A, and its downstream target MCAM, promote Ewing Sarcoma cell migration and metastasisQ41073699
Gene knockout of Zmym3 in mice arrests spermatogenesis at meiotic metaphase with defects in spindle assembly checkpointQ41084001
Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma.Q41139182
Synthetic lethality between the cohesin subunits STAG1 and STAG2 in diverse cancer contextsQ41155792
Cell-to-cell heterogeneity of EWSR1-FLI1 activity determines proliferation/migration choices in Ewing sarcoma cells.Q41224633
The Neurological Compromised Spine Due to Ewing Sarcoma. What First: Surgery or Chemotherapy? Therapy, Survival, and Neurological Outcome of 15 Cases With Primary Ewing Sarcoma of the Vertebral Column.Q41451017
ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repairQ41967452
Increased survival and cell cycle progression pathways are required for EWS/FLI1-induced malignant transformationQ42126638
EWS/FLI-responsive GGAA microsatellites exhibit polymorphic differences between European and African populations.Q42224745
Ewing sarcoma with novel translocation t(2;16) producing an in-frame fusion of FUS and FEV.Q42379007
MultiDimensional ClinOmics for Precision Therapy of Children and Adolescent Young Adults with Relapsed and Refractory Cancer: A Report from the Center for Cancer Research.Q42385390
Primary disseminated multifocal Ewing sarcoma: results of the Euro-EWING 99 trial.Q43023369
High-dose melphalan, etoposide, total-body irradiation, and autologous stem-cell reconstitution as consolidation therapy for high-risk Ewing's sarcoma does not improve prognosis.Q43626751
FDG-PET for detection of pulmonary metastases from malignant primary bone tumors: comparison with spiral CT.Q43634477
Predictive factors of histological response to primary chemotherapy in Ewing's sarcomaQ43699064
The value of high-dose chemotherapy in patients with first relapsed Ewing sarcomaQ43833260
Second malignancies after ewing tumor treatment in 690 patients from a cooperative German/Austrian/Dutch studyQ43873502
An evaluation of [F-18]-fluorodeoxy-D-glucose positron emission tomography, bone scan, and bone marrow aspiration/biopsy as staging investigations in Ewing sarcomaQ43922197
Local therapy in localized Ewing tumors: results of 1058 patients treated in the CESS 81, CESS 86, and EICESS 92 trialsQ44263749
Vincristine, irinotecan, and temozolomide in patients with relapsed and refractory Ewing sarcomaQ44611540
Ewing sarcomas with p53 mutation or p16/p14ARF homozygous deletion: a highly lethal subset associated with poor chemoresponseQ45230556
Rarity of Ewing's sarcoma among U.S. Negro childrenQ45242237
Rarity of Ewing's tumour in NegroesQ46761653
Positron emission tomography for staging of pediatric sarcoma patients: results of a prospective multicenter trial.Q46874365
P433issue1
P921main subjectEwing sarcomaQ1138580
P577publication date2018-07-05
P1433published inNature Reviews Disease PrimersQ24908540
P1476titleEwing sarcoma
P478volume4

Reverse relations

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main subject (P921)
Q64375291A case of primary cutaneous Ewing sarcoma in a neutropenic patient
Q64251223A nomogram to predict prognosis in Ewing sarcoma of bone
Q64055912Anatomic Origin of Osteochondrogenic Progenitors Impacts Sensitivity to EWS-FLI1-Induced Transformation
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