Pharmacokinetics and Metabolism of Bisoprolol Enantiomers in Humans

Pharmacokinetics and Metabolism of Bisoprolol Enantiomers in Humans is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1021/JS970316D
P698PubMed publication ID9523980

P2093author name stringTakehiko Suzuki
Yuji Horikiri
Masakazu Mizobe
P2860cites workBeta 1-selectivity of bisoprolol, a new beta-adrenoceptor antagonist, in anesthetized dogs and guinea pigsQ28259340
Basic pharmacokinetics of bisoprolol, a new highly beta 1-selective adrenoceptor antagonistQ28282702
Stereoselective renal clearance of pindolol in humansQ34563398
The human hepatic cytochromes P450 involved in drug metabolismQ36258518
Chirality. Clinical pharmacokinetic and pharmacodynamic considerationsQ37920866
Enantioselective aspects of drug action and disposition: therapeutic pitfallsQ38725198
Bisoprolol: a new beta-adrenoceptor blocking drugQ39467857
Bisoprolol. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in hypertension and angina pectorisQ39471086
Importance of drug enantiomers in clinical pharmacologyQ39834900
Pharmacokinetic drug interactions with antimicrobial agentsQ40720380
Comparison of substrate metabolism by wild type CYP2D6 protein and a variant containing methionine, not valine, at position 374.Q41315412
Dose proportionality of bisoprolol enantiomers in humans after oral administration of the racemate.Q54026055
Enzymatic basis of the debrisoquine/sparteine-type genetic polymorphism of drug oxidation. Characterization of bufuralol 1'-hydroxylation in liver microsomes of in vivo phenotyped carriers of the genetic deficiencyQ69464156
Pharmacodynamic and pharmacokinetic differences between drug enantiomers in humans: an overviewQ69567234
Interaction of bisoprolol with cimetidine and rifampicinQ69890125
Sensitive determination of bisoprolol enantiomers in plasma and urine by high-performance liquid chromatography using fluorescence detection, and application to preliminary study in humansQ72662069
Stereoselective pharmacokinetics of bisoprolol after intravenous and oral administration in beagle dogsQ73327737
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectbisoprololQ412515
enantiomerQ494483
pharmacokineticsQ323936
P304page(s)289-294
P577publication date1998-03-01
P1433published inJournal of Pharmaceutical SciencesQ3186933
P1476titlePharmacokinetics and Metabolism of Bisoprolol Enantiomers in Humans
P478volume87

Reverse relations

cites work (P2860)
Q33859044Anastrozole-related acute hepatitis with autoimmune features: a case report
Q39127810CYP2D6 Genetic Variation and Beta-Blocker Maintenance Dose in Patients with Heart Failure
Q90466333Cardiogenic shock induced by bisoprolol in a patient with CYP2D6 variant. A case report
Q34146105Chiral Recognition Mechanisms of four β-Blockers by HPLC with Amylose Chiral Stationary Phase
Q37288542Chronic heart failure: beta-blockers and pharmacogenetics
Q35646205Computational predictions of the site of metabolism of cytochrome P450 2D6 substrates: comparative analysis, molecular docking, bioactivation and toxicological implications
Q36299177Development and validation of an HPLC-UV method for the simultaneous determination of the antipsychotics clozapine, olanzapine and quetiapine, several beta-blockers and their metabolites.
Q34761052Evaluation of a generic physiologically based pharmacokinetic model for lineshape analysis
Q37997025Impact of obesity on drug metabolism and elimination in adults and children
Q34727832In Silico comparison between metoprolol succinate and bisoprolol on 24-hour systolic blood pressures
Q47818380Population Pharmacokinetic Analysis of Bisoprolol in Patients with Stable Coronary Artery Disease.
Q39531576Population pharmacokinetics of bisoprolol in patients with chronic heart failure.
Q48192886Range of therapeutic prothipendyl and prothipendyl sulfoxide concentrations in clinical blood samples
Q34620990Recent applications of stereoselective chromatography
Q89915463Stereochemical facets of clinical β-blockers: An overview
Q35051413Stereoselective chromatography of cardiovascular drugs: an update
Q77379475Stereoselective metabolism of bisoprolol enantiomers in dogs and humans
Q32103802Summary of information on human CYP enzymes: human P450 metabolism data