Gene therapy for the hemophilias

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Gene therapy for the hemophilias is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0065-3519(97)80006-7
P698PubMed publication ID9395731

P2093author name stringJ Walter
K A High
P2860cites workSite-specific integration by adeno-associated virusQ24558738
Structure of human factor VIIIQ28630991
Nucleotide sequence of the gene for human factor IX (antihemophilic factor B)Q28646323
An alternative approach to somatic cell gene therapyQ33571138
Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogsQ33671665
Expression of human factor IX in rabbit hepatocytes by retrovirus-mediated gene transfer: potential for gene therapy of hemophilia B.Q33739384
Canine hemophilia B resulting from a point mutation with unusual consequencesQ34326780
A prospective study of human immunodeficiency virus type 1 infection and the development of AIDS in subjects with hemophiliaQ34417597
Cellular and humoral immune responses to adenoviral vectors containing factor IX gene: tolerization of factor IX and vector antigens allows for long-term expressionQ34615481
Gene therapy for hemophilia A: production of therapeutic levels of human factor VIII in vivo in miceQ34675871
In vivo hepatic gene therapy: complete albeit transient correction of factor IX deficiency in hemophilia B dogsQ35109095
Lack of expression from a retroviral vector after transduction of murine hematopoietic stem cells is associated with methylation in vivoQ35123124
Cellular immunity to viral antigens limits E1-deleted adenoviruses for gene therapyQ35232341
In vivo production of human factor VII in mice after intrasplenic implantation of primary fibroblasts transfected by receptor-mediated, adenovirus-augmented gene deliveryQ35387018
Ablation of E2A in recombinant adenoviruses improves transgene persistence and decreases inflammatory response in mouse liverQ35559973
Helper virus induced T cell lymphoma in nonhuman primates after retroviral mediated gene transferQ36231835
Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vectorQ36663364
Genetics of adeno-associated virus: isolation and preliminary characterization of adeno-associated virus type 2 mutantsQ36893013
Expression of human factor IX in mice after injection of genetically modified myoblastsQ36950396
High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles.Q37093747
Gene therapy via primary myoblasts: long-term expression of factor IX protein following transplantation in vivoQ37300317
Expression of human factor IX in rat capillary endothelial cells: toward somatic gene therapy for hemophilia BQ37594306
Successful expression of human factor IX following repeat administration of adenoviral vector in mice.Q37685172
Haemophilia A: database of nucleotide substitutions, deletions, insertions and rearrangements of the factor VIII geneQ40506896
An evaluation of receptor-mediated gene transfer using synthetic DNA-ligand complexesQ40655841
Gene therapy: adenovirus vectors.Q40835892
Efficient transfection of primary cells in a canine hemophilia B model using adenovirus-polylysine-DNA complexesQ41484655
In vivo gene therapy of hemophilia B: sustained partial correction in factor IX-deficient dogsQ41524708
Absence of hepatitis after treatment with a pasteurized factor VIII concentrate in patients with hemophilia and no previous transfusionsQ41771926
Long-term gene expression and phenotypic correction using adeno-associated virus vectors in the mammalian brainQ42280576
Absence of anti-human immunodeficiency virus types 1 and 2 seroconversion after the treatment of hemophilia A or von Willebrand's disease with pasteurized factor VIII concentrateQ45846717
Response to infusions of polyelectrolyte fractionated human factor VIII concentrate in human haemophilia A and von Willebrand's diseaseQ45864427
Long-term hepatic adenovirus-mediated gene expression in mice following CTLA4Ig administrationQ45866667
Recombinant IL-12 prevents formation of blocking IgA antibodies to recombinant adenovirus and allows repeated gene therapy to mouse lung.Q45867442
Targeted disruption of the mouse factor VIII gene produces a model of haemophilia AQ45868121
Characterization of the human factor VIII geneQ48385931
P407language of work or nameEnglishQ1860
P304page(s)119-34
P577publication date1997-01-01
P1433published inAdvances in veterinary medicineQ27714281
P1476titleGene therapy for the hemophilias
P478volume40

Reverse relations

Q34777289Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins.cites workP2860

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