| scholarly article | Q13442814 |
| P356 | DOI | 10.1172/JCI0215780 |
| 10.1172/JCI15780 | ||
| P932 | PMC publication ID | 150421 |
| P698 | PubMed publication ID | 12189244 |
| P50 | author | James Wilson | Q16947166 |
| Daniel Weiner | Q43194802 | ||
| Alberto Auricchio | Q56950196 | ||
| P2093 | author name string | Lili Wang | |
| Roberto Calcedo | |||
| Erin O'Connor | |||
| Markus Hildinger | |||
| Guang-Ping Gao | |||
| P2860 | cites work | Adeno-associated virus type 6 (AAV6) vectors mediate efficient transduction of airway epithelial cells in mouse lungs compared to that of AAV2 vectors | Q24529153 |
| Transduction with recombinant adeno-associated virus for gene therapy is limited by leading-strand synthesis | Q24684374 | ||
| The lung as a route for systemic delivery of therapeutic proteins and peptides | Q24792013 | ||
| Isolation of highly infectious and pure adeno-associated virus type 2 vectors with a single-step gravity-flow column. | Q31934499 | ||
| Cloning and characterization of adeno-associated virus type 5. | Q33641228 | ||
| Phenotypic correction of factor IX deficiency in skin fibroblasts of hemophilic dogs | Q33671665 | ||
| Infectious clones and vectors derived from adeno-associated virus (AAV) serotypes other than AAV type 2. | Q33781976 | ||
| Successful readministration of adeno-associated virus vectors to the mouse lung requires transient immunosuppression during the initial exposure | Q33786029 | ||
| Repeat transduction in the mouse lung by using adeno-associated virus vectors with different serotypes | Q33793801 | ||
| Adeno-associated virus type 5 (AAV5) but not AAV2 binds to the apical surfaces of airway epithelia and facilitates gene transfer | Q33802811 | ||
| Adeno-associated virus vectors for gene therapy: more pros than cons? | Q34080580 | ||
| Gene transfer as an approach to treating hemophilia | Q34131160 | ||
| Gene therapy for hemophilia B: AAV-mediated transfer of the gene for coagulation factor IX to human muscle. | Q34367815 | ||
| Endosomal processing limits gene transfer to polarized airway epithelia by adeno-associated virus. | Q34433170 | ||
| Cloning of adeno-associated virus type 4 (AAV4) and generation of recombinant AAV4 particles. | Q35892008 | ||
| Stable gene transfer and expression of human blood coagulation factor IX after intramuscular injection of recombinant adeno-associated virus | Q36159178 | ||
| Cloning of adeno-associated virus into pBR322: rescue of intact virus from the recombinant plasmid in human cells | Q36288360 | ||
| Sustained correction of bleeding disorder in hemophilia B mice by gene therapy | Q36454880 | ||
| A factor IX-deficient mouse model for hemophilia B gene therapy | Q36602472 | ||
| Stable in vivo expression of the cystic fibrosis transmembrane conductance regulator with an adeno-associated virus vector | Q36663364 | ||
| Gene therapy vectors based on adeno-associated virus type 1. | Q39550492 | ||
| Transduction of well-differentiated airway epithelium by recombinant adeno-associated virus is limited by vector entry. | Q39594915 | ||
| Hybrid vectors based on adeno-associated virus serotypes 2 and 5 for muscle-directed gene transfer | Q39603323 | ||
| Filovirus-pseudotyped lentiviral vector can efficiently and stably transduce airway epithelia in vivo | Q40606944 | ||
| Binding of adeno-associated virus type 5 to 2,3-linked sialic acid is required for gene transfer | Q40819170 | ||
| Purification of recombinant adeno-associated virus vectors by column chromatography and its performance in vivo | Q40846908 | ||
| Factors influencing recombinant adeno-associated virus production | Q41049528 | ||
| Haemophilia prophylaxis in young patients--a long-term follow-up | Q41497194 | ||
| cis-acting elements that confer lung epithelial cell expression of the CC10 gene | Q41613110 | ||
| Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector. | Q41722852 | ||
| Sustained expression of therapeutic level of factor IX in hemophilia B dogs by AAV-mediated gene therapy in liver | Q41753510 | ||
| Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo | Q41894646 | ||
| Direct intramuscular injection with recombinant AAV vectors results in sustained expression in a dog model of hemophilia | Q45060641 | ||
| Recombinant adeno-associated virus for muscle directed gene therapy | Q45764433 | ||
| Molecular cloning of adeno-associated virus variant genomes and generation of infectious virus by recombination in mammalian cells | Q45796829 | ||
| Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector | Q45855552 | ||
| Persistent expression of canine factor IX in hemophilia B canines | Q45862802 | ||
| Several log increase in therapeutic transgene delivery by distinct adeno-associated viral serotype vectors | Q45873434 | ||
| Muscle-directed gene transfer and transient immune suppression result in sustained partial correction of canine hemophilia B caused by a null mutation | Q45879591 | ||
| Gene therapy for the hemophilias | Q56908635 | ||
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 499-504 | |
| P577 | publication date | 2002-08-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Noninvasive gene transfer to the lung for systemic delivery of therapeutic proteins | |
| P478 | volume | 110 |
| Q40131362 | A comparative analysis of novel fluorescent proteins as reporters for gene transfer studies. |
| Q36708300 | AAV-mediated gene transfer for retinal diseases |
| Q34470293 | AAV5-mediated gene transfer to the parotid glands of non-human primates |
| Q35566831 | Adeno-associated viral vectors for retinal gene transfer. |
| Q26823156 | Adeno-associated virus for cystic fibrosis gene therapy |
| Q35016463 | Adeno-associated virus serotype 9 vectors transduce murine alveolar and nasal epithelia and can be readministered. |
| Q45367165 | Adeno-associated virus serotype 9-mediated pulmonary transgene expression: effect of mouse strain, animal gender and lung inflammation |
| Q47934211 | Adenovirus-mediated erythropoietin production by airway epithelia is enhanced by apical localization of the coxsackie-adenovirus receptor in vivo |
| Q35628533 | Advances in AAV-mediated gene transfer for the treatment of inherited disorders. |
| Q36562646 | Alleviation of lung inflammatory responses by adeno-associated virus 2/9 vector carrying CC10 in OVA-sensitized mice |
| Q45884158 | An optimized protocol for detection of E. coli beta-galactosidase in lung tissue following gene transfer. |
| Q37149675 | Analysis of adeno-associated virus progenitor cell transduction in mouse lung. |
| Q35188510 | Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands |
| Q33782838 | Attenuation of monocrotaline-induced pulmonary hypertension by luminal adeno-associated virus serotype 9 gene transfer of prostacyclin synthase |
| Q33822204 | BALB/c mice show impaired hepatic tolerogenic response following AAV gene transfer to the liver |
| Q29248141 | Barriers to inhaled gene therapy of obstructive lung diseases: A review |
| Q37858512 | Current status and future directions of gene and cell therapy for cystic fibrosis |
| Q35043830 | Current status of gene therapy for inherited lung diseases |
| Q39872579 | Cystic fibrosis gene therapy: successes, failures and hopes for the future |
| Q36509719 | Distinct classes of proteasome-modulating agents cooperatively augment recombinant adeno-associated virus type 2 and type 5-mediated transduction from the apical surfaces of human airway epithelia |
| Q45162912 | Dual therapeutic utility of proteasome modulating agents for pharmaco-gene therapy of the cystic fibrosis airway. |
| Q45422036 | Effect of tolerance induction to immunodominant T-cell epitopes of Sendai virus on gene expression following repeat administration to lung |
| Q41197893 | Efficient gene transfer into the mouse lung by fetal intratracheal injection of rAAV2/6.2. |
| Q64376808 | Efficient retrograde neuronal transduction utilizing self-complementary AAV1 |
| Q24538483 | Efficient transduction of vascular endothelial cells with recombinant adeno-associated virus serotype 1 and 5 vectors |
| Q36981816 | Fluorescently tagged laminin subunits facilitate analyses of the properties, assembly and processing of laminins in live and fixed lung epithelial cells and keratinocytes |
| Q35904424 | Gene therapy for cystic fibrosis: an example for lung gene therapy |
| Q35186114 | Gene therapy progress and prospects: gene therapy of lysosomal storage disorders |
| Q45880182 | Genetic modification of adeno-associated viral vector type 2 capsid enhances gene transfer efficiency in polarized human airway epithelial cells. |
| Q40642180 | Helper virus-free, optically controllable, and two-plasmid-based production of adeno-associated virus vectors of serotypes 1 to 6. |
| Q42000966 | IDS crossing of the blood-brain barrier corrects CNS defects in MPSII mice |
| Q35091006 | Immunological hurdles to lung gene therapy. |
| Q40928395 | Immunological ignorance allows long-term gene expression after perinatal recombinant adeno-associated virus-mediated gene transfer to murine airways |
| Q33768129 | In utero lung gene transfer using adeno-associated viral and lentiviral vectors in mice. |
| Q36097743 | Intracellular trafficking of adeno-associated viral vectors. |
| Q36114234 | Intranasal vaccination with AAV5 and 9 vectors against human papillomavirus type 16 in rhesus macaques |
| Q34434903 | Intranasal vaccination with recombinant adeno-associated virus type 5 against human papillomavirus type 16 L1 |
| Q40488137 | Intrapleural administration of a serotype 5 adeno-associated virus coding for alpha1-antitrypsin mediates persistent, high lung and serum levels of alpha1-antitrypsin |
| Q36315561 | Lack of repeat transduction by recombinant adeno-associated virus type 5/5 vectors in the mouse airway |
| Q36949698 | Lentivirus vector can be readministered to nasal epithelia without blocking immune responses |
| Q45414317 | Long-term persistence of gene expression from adeno-associated virus serotype 5 in the mouse airways |
| Q37601170 | Long-term transduction of miniature pig parotid glands using serotype 2 adeno-associated viral vectors |
| Q34384998 | Novel adeno-associated viruses derived from pig tissues transduce most major organs in mice |
| Q33575791 | Optimization of Streptomyces bacteriophage phi C31 integrase system to prevent post integrative gene silencing in pulmonary type II cells |
| Q37158813 | Postentry processing of recombinant adeno-associated virus type 1 and transduction of the ferret lung are altered by a factor in airway secretions. |
| Q22306014 | Progress towards gene therapy for cystic fibrosis |
| Q36401352 | Pseudotyped adeno-associated virus 2/9-delivered CCL11 shRNA alleviates lung inflammation in an allergen-sensitized mouse model |
| Q34775483 | Recent developments in adeno-associated virus vector technology |
| Q39500834 | Recombinant AAV serotype and capsid mutant comparison for pulmonary gene transfer of alpha-1-antitrypsin using invasive and noninvasive delivery |
| Q35904461 | Recombinant adeno-associated viral (rAAV) vectors as therapeutic tools for Duchenne muscular dystrophy (DMD). |
| Q36853653 | Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics |
| Q34044390 | Riboswitch-mediated Attenuation of Transgene Cytotoxicity Increases Adeno-associated Virus Vector Yields in HEK-293 Cells |
| Q35150199 | Second-strand genome conversion of adeno-associated virus type 2 (AAV-2) and AAV-5 is not rate limiting following apical infection of polarized human airway epithelia |
| Q37596958 | Secretion of a TNFR:Fc fusion protein following pulmonary administration of pseudotyped adeno-associated virus vectors |
| Q34132125 | Sorting of transgenic secretory proteins in rhesus macaque parotid glands after adenovirus-mediated gene transfer. |
| Q35546541 | Species-specific differences in mouse and human airway epithelial biology of recombinant adeno-associated virus transduction |
| Q27679454 | Structural Insights into Adeno-Associated Virus Serotype 5 |
| Q39602375 | Suppression of transforming growth factor β1 in lung alveolar epithelium-derived cells using adeno-associated virus type 2/5 vectors to carry short hairpin RNA. |
| Q64228945 | Targeted Gene Delivery through the Respiratory System: Rationale for Intratracheal Gene Transfer |
| Q63246426 | Tetrafunctional Block Copolymers Promote Lung Gene Transfer in Newborn Piglets |
| Q37286686 | The TLR9-MyD88 pathway is critical for adaptive immune responses to adeno-associated virus gene therapy vectors in mice |
| Q39735974 | The lung as a metabolic factory for gene therapy. |
| Q59356531 | The murine lung as a factory to produce secreted intrapulmonary and circulatory proteins |
| Q41944937 | The transduction of rat submandibular glands by an adenoviral vector carrying the human growth hormone gene is associated with limited and reversible changes at the infusion site. |
| Q33713277 | Transduction efficiencies of novel AAV vectors in mouse airway epithelium in vivo and human ciliated airway epithelium in vitro. |
| Q44322895 | Treatment of experimental asthma by long-term gene therapy directed against IL-4 and IL-13. |
| Q35239472 | Unique biologic properties of recombinant AAV1 transduction in polarized human airway epithelia. |
| Q40273201 | Using magnetic forces to enhance non-viral gene transfer to airway epithelium in vivo |
| Q43930000 | Validation of recombinant Sendai virus in a non-natural host model. |
| Q36965152 | Versatility of AAV vectors for retinal gene transfer |
| Q36712185 | Viral vector-mediated and cell-based therapies for treatment of cystic fibrosis |
| Q35847178 | Viral-mediated gene therapy for the muscular dystrophies: successes, limitations and recent advances |
| Q58700020 | Widespread airway distribution and short-term phenotypic correction of cystic fibrosis pigs following aerosol delivery of piggyBac/adenovirus |
| Q38949076 | rAAV-CFTRΔR Rescues the Cystic Fibrosis Phenotype in Human Intestinal Organoids and Cystic Fibrosis Mice |
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