Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell

scientific article published on 01 October 2018

Induction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41591-018-0201-9
P932PMC publication ID6511988
P698PubMed publication ID30275568

P50authorCarl H. JuneQ19277113
Marco RuellaQ56947896
Simon F LaceyQ56978267
Bruce L. LevineQ85544154
Tyler J ReichQ88924956
Terry J FryQ89329430
Stephan A GruppQ104495066
P2093author name stringFrederic D Bushman
Jun Xu
John Scholler
Hans Bitter
Michael Klichinsky
Olga Shestova
David M Barrett
Farzana Nazimuddin
J Joseph Melenhorst
Shannon L Maude
Regina M Young
Irina Kulikovskaya
Joseph A Fraietta
Prachi R Patel
David E Ambrose
Elena J Orlando
Vijay G Bhoj
Christopher L Nobles
Saar I Gill
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The Addition of the BTK Inhibitor Ibrutinib to Anti-CD19 Chimeric Antigen Receptor T Cells (CART19) Improves Responses against Mantle Cell Lymphoma.Q40050634
Chimeric receptors with 4-1BB signaling capacity provoke potent cytotoxicity against acute lymphoblastic leukemia.Q40590332
Chimeric receptors containing CD137 signal transduction domains mediate enhanced survival of T cells and increased antileukemic efficacy in vivoQ42938990
Retroviral and Lentiviral Safety Analysis of Gene-Modified T Cell Products and Infused HIV and Oncology PatientsQ45875400
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CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy.Q48272279
Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia.Q49029195
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectleukemiaQ29496
P304page(s)1499-1503
P577publication date2018-10-01
P1433published inNature MedicineQ1633234
P1476titleInduction of resistance to chimeric antigen receptor T cell therapy by transduction of a single leukemic B cell
P478volume24

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