Glycine Relieves Intestinal Injury by Maintaining mTOR Signaling and Suppressing AMPK, TLR4, and NOD Signaling in Weaned Piglets after Lipopolysaccharide Challenge

scholarly article by Xiao Xu published in July 2018

Glycine Relieves Intestinal Injury by Maintaining mTOR Signaling and Suppressing AMPK, TLR4, and NOD Signaling in Weaned Piglets after Lipopolysaccharide Challenge is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/IJMS19071980
P932PMC publication ID6073676
P698PubMed publication ID29986455

P50authorYulan LiuQ42368275
P2093author name stringHuiling Zhu
Xiao Xu
Xiuying Wang
Yongqing Hou
Congcong Liu
Bing Dai
Xiuting Liu
Huanting Wu
P2860cites workAccurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genesQ24534395
Peroxisomal NADP-Dependent Isocitrate Dehydrogenase. Characterization and Activity Regulation during Natural SenescenceQ24555157
Medium-chain TAG improve intestinal integrity by suppressing toll-like receptor 4, nucleotide-binding oligomerisation domain proteins and necroptosis signalling in weanling piglets challenged with lipopolysaccharide.Q51735927
β-aminoisobutyric acid attenuates LPS-induced inflammation and insulin resistance in adipocytes through AMPK-mediated pathway.Q53076733
Fish oil enhances intestinal barrier function and inhibits corticotropin-releasing hormone/corticotropin-releasing hormone receptor 1 signalling pathway in weaned pigs after lipopolysaccharide challenge.Q53121886
Aspartate attenuates intestinal injury and inhibits TLR4 and NODs/NF-κB and p38 signaling in weaned pigs after LPS challenge.Q53166806
Asparagine attenuates intestinal injury, improves energy status and inhibits AMP-activated protein kinase signalling pathways in weaned piglets challenged with Escherichia coli lipopolysaccharide.Q53377997
Asparagine attenuates hepatic injury caused by lipopolysaccharide in weaned piglets associated with modulation of Toll-like receptor 4 and nucleotide-binding oligomerisation domain protein signalling and their negative regulators.Q54265460
Intestinal permeability: functional assessment and significanceQ55036938
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Toll-like receptor (TLR) 2 agonists ameliorate indomethacin-induced murine ileitis by suppressing the TLR4 signalingQ87103315
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Molecular neurobiology of mTORQ28072706
Citrate synthase: structure, control, and mechanismQ28287397
Essential Role of Growth Hormone and IGF-1 in Therapeutic Effect of Ghrelin in the Course of Acetic Acid-Induced Colitis.Q33838384
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Toll-like receptor 4 mediates lipopolysaccharide-induced muscle catabolism via coordinate activation of ubiquitin-proteasome and autophagy-lysosome pathwaysQ34421809
Irradiation induced injury reduces energy metabolism in small intestine of Tibet minipigsQ34634439
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Fatty acids, inflammation and intestinal health in pigsQ36045305
Bifidobacterium adolescentis protects against necrotizing enterocolitis and upregulates TOLLIP and SIGIRR in premature neonatal ratsQ36241201
Restoration of barrier function in injured intestinal mucosaQ36788890
Emerging role of Toll-like receptors in atherosclerosisQ37316197
Maternal protein restriction affects gene expression and enzyme activity of intestinal disaccharidases in adult rat offspring.Q37371419
PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditureQ37412140
AMP-activated protein kinase mediates the interferon-gamma-induced decrease in intestinal epithelial barrier functionQ37459893
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Ethanolamine enhances the proliferation of intestinal epithelial cells via the mTOR signaling pathway and mitochondrial functionQ38777866
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Strengthening of the intestinal epithelial tight junction by Bifidobacterium bifidumQ38898593
Inflammatory disease caused by intestinal pathobiontsQ39131979
Transport and metabolic processes in the small intestineQ39133275
Dietary glycine prevents peptidoglycan polysaccharide-induced reactive arthritis in the rat: role for glycine-gated chloride channelQ39522126
AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1.Q39542812
Molecular cloning and functional characterization of porcine nucleotide-binding oligomerization domain-2 (NOD2).Q40121808
Superior mesenteric artery is more important than inferior mesenteric artery in maintaining colonic mucosal perfusion and integrity in ratsQ41108814
Exogenous Ghrelin Accelerates the Healing of Acetic Acid-Induced Colitis in RatsQ41191182
Obestatin Accelerates the Healing of Acetic Acid-Induced Colitis in Rats.Q41360298
Ghrelin accelerates the healing of cysteamine-induced duodenal ulcers in rats.Q41843364
Expression of toll-like receptor 2 (TLR2) in porcine leukocyte subsets and tissuesQ42522854
Influence of glycine on intestinal ischemia-reperfusion injuryQ43900777
Dietary glycine prevents chemical-induced experimental colitis in the rat.Q44569538
Effect of L-arginine on intestinal mucosal immune barrier function in weaned pigs after Escherichia coli LPS challengeQ44660012
Asparagine improves intestinal integrity, inhibits TLR4 and NOD signaling, and differently regulates p38 and ERK1/2 signaling in weanling piglets after LPS challenge.Q44866384
Dietary supplementation of aspartate enhances intestinal integrity and energy status in weanling piglets after lipopolysaccharide challengeQ44872695
A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle carbohydrate oxidation during sepsis in rodent skeletal muscle.Q46346112
Dietary arginine supplementation alleviates intestinal mucosal disruption induced by Escherichia coli lipopolysaccharide in weaned pigsQ46753293
Reduction of body weight by dietary garlic is associated with an increase in uncoupling protein mRNA expression and activation of AMP-activated protein kinase in diet-induced obese miceQ47355501
Aspartate alleviates liver injury and regulates mRNA expressions of TLR4 and NOD signaling-related genes in weaned pigs after lipopolysaccharide challenge.Q50667849
Zinc enhances intestinal epithelial barrier function through the PI3K/AKT/mTOR signaling pathway in Caco-2 cells.Q50895354
N-Acetylcysteine improves intestinal function in lipopolysaccharides-challenged piglets through multiple signaling pathways.Q51107254
Glycine selectively reduces intestinal injury during endotoxemia.Q51711271
Effect of Endotoxemia in Suckling Rats on Pancreatic Integrity and Exocrine Function in Adults: A Review Report.Q51735051
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectmolecular biologyQ7202
catalysisQ82264
toll-like receptorQ408004
lipopolysaccharideQ421804
P304page(s)1980
P577publication date2018-07-06
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleGlycine Relieves Intestinal Injury by Maintaining mTOR Signaling and Suppressing AMPK, TLR4, and NOD Signaling in Weaned Piglets after Lipopolysaccharide Challenge
P478volume19

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cites work (P2860)
Q99725481Anti-Inflammatory Potential of Cow, Donkey and Goat Milk Extracellular Vesicles as Revealed by Metabolomic Profile
Q92583953Holly polyphenols alleviate intestinal inflammation and alter microbiota composition in lipopolysaccharide-challenged pigs
Q93041989Long non-coding RNA profiling in LPS-induced intestinal inflammation model: New insight into pathogenesis

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