Is there a role for immunotherapy in HER2-positive breast cancer?

Is there a role for immunotherapy in HER2-positive breast cancer? is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41523-018-0072-8
P932PMC publication ID6093898
P698PubMed publication ID30131972

P2093author name stringJavier Cortes
Jose Perez-Garcia
Esther Holgado
Maria Gion
P2860cites workImmune modulation of pathologic complete response after neoadjuvant HER2-directed therapies in the NeoSphere trial.Q40521722
Tumor infiltrating lymphocytes are prognostic in triple negative breast cancer and predictive for trastuzumab benefit in early breast cancer: results from the FinHER trialQ43951696
Overall survival benefit with lapatinib in combination with trastuzumab for patients with human epidermal growth factor receptor 2-positive metastatic breast cancer: final results from the EGF104900 StudyQ46256397
Tumor-infiltrating lymphocytes in Breast Cancer and implications for clinical practiceQ47736637
Neoadjuvant buparlisib plus trastuzumab and paclitaxel for women with HER2+ primary breast cancer: A randomised, double-blind, placebo-controlled phase II trial (NeoPHOEBE).Q47782850
Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.Q50908445
Tumor-infiltrating lymphocytes and response to neoadjuvant chemotherapy with or without carboplatin in human epidermal growth factor receptor 2-positive and triple-negative primary breast cancers.Q51022930
First-in-human phase 1 study of margetuximab (MGAH22), an Fc-modified chimeric monoclonal antibody, in patients with HER2-positive advanced solid tumors.Q51170722
Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.Q52907227
Elements Related to Heterogeneity of Antibody-Dependent Cell Cytotoxicity in Patients Under Trastuzumab Therapy for Primary Operable Breast Cancer Overexpressing Her2Q62604205
Pilot Study of the Mechanism of Action of Preoperative Trastuzumab in Patients with Primary Operable Breast Tumors Overexpressing HER2Q62604209
Conditionally reprogrammed pancreatic cancer cells: A novel patient-derived cell line model for human pancreatic cancer studiesQ90068935
Cancer genome landscapesQ22242276
Comprehensive molecular portraits of human breast tumoursQ24630844
Anti-ErbB-2 mAb therapy requires type I and II interferons and synergizes with anti-PD-1 or anti-CD137 mAb therapyQ28235277
Signatures of mutational processes in human cancerQ29547191
Genomic analysis reveals that immune function genes are strongly linked to clinical outcome in the North Central Cancer Treatment Group n9831 Adjuvant Trastuzumab Trial.Q35102480
Prospective Biomarker Analysis of the Randomized CHER-LOB Study Evaluating the Dual Anti-HER2 Treatment With Trastuzumab and Lapatinib Plus Chemotherapy as Neoadjuvant Therapy for HER2-Positive Breast CancerQ36064908
Association of Stromal Tumor-Infiltrating Lymphocytes With Recurrence-Free Survival in the N9831 Adjuvant Trial in Patients With Early-Stage HER2-Positive Breast CancerQ36463604
Molecular Heterogeneity and Response to Neoadjuvant Human Epidermal Growth Factor Receptor 2 Targeting in CALGB 40601, a Randomized Phase III Trial of Paclitaxel Plus Trastuzumab With or Without Lapatinib.Q37166436
Tumor-infiltrating lymphocytes, breast cancer subtypes and therapeutic efficacyQ37194864
Pertuzumab: a new targeted therapy for HER2-positive metastatic breast cancerQ38126859
Targeting HER2 for the treatment of breast cancerQ38317974
Tumour-infiltrating lymphocytes in advanced HER2-positive breast cancer treated with pertuzumab or placebo in addition to trastuzumab and docetaxel: a retrospective analysis of the CLEOPATRA studyQ38376822
Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO TrialQ38407917
The genomic landscape of breast cancer and its interaction with host immunityQ38915694
Immunogenic cell death in cancer and infectious diseaseQ38982422
Strongly enhanced antitumor activity of trastuzumab and pertuzumab combination treatment on HER2-positive human xenograft tumor modelsQ39771295
Immunoglobulin G fragment C receptor polymorphisms and clinical efficacy of trastuzumab-based therapy in patients with HER-2/neu-positive metastatic breast cancer.Q40001571
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimmunotherapyQ1427096
P304page(s)21
P577publication date2018-01-01
P1433published inNPJ Breast CancerQ27727120
P1476titleIs there a role for immunotherapy in HER2-positive breast cancer?
P478volume4

Reverse relations

cites work (P2860)
Q91272277Clinicopathological values of PD-L1 expression in HER2-positive breast cancer
Q90009685Immunogenicity of rat-neu+ mouse mammary tumours determines the T cell-dependent therapeutic efficacy of anti-neu monoclonal antibody treatment
Q92416882Resveratrol targets PD-L1 glycosylation and dimerization to enhance antitumor T-cell immunity
Q90644277Two may be better than one: PD-1/PD-L1 blockade combination approaches in metastatic breast cancer

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