Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling

scientific article published on 13 July 2018

Structural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1681/ASN.2017121275
P932PMC publication ID6115659
P698PubMed publication ID30006415

P50authorZeyang JiQ58888935
Yuan ShangQ82428027
P2093author name stringFei Ye
Lin Lin
Rongguang Zhang
Jinwei Zhu
Zhuangfeng Weng
P2860cites workA role for the PDZ-binding domain of the coxsackie B virus and adenovirus receptor (CAR) in cell adhesion and growthQ24301014
Positionally cloned gene for a novel glomerular protein--nephrin--is mutated in congenital nephrotic syndromeQ24314612
PHENIX: a comprehensive Python-based system for macromolecular structure solutionQ24654617
Processing of X-ray diffraction data collected in oscillation modeQ26778468
Cell biology and pathology of podocytesQ26853664
Structural basis of the myosin X PH1N-PH2-PH1C tandem as a specific and acute cellular PI(3,4,5)P3 sensorQ27674679
Coot: model-building tools for molecular graphicsQ27860505
Phasercrystallographic softwareQ27860930
The membrane-associated guanylate kinase protein MAGI-1 binds megalin and is present in glomerular podocytesQ28207315
Cell junction-associated proteins IQGAP1, MAGI-2, CASK, spectrins, and alpha-actinin are components of the nephrin multiprotein complexQ28570208
Slit diaphragms contain tight junction proteinsQ28573180
The murine nephrin gene is specifically expressed in kidney, brain and pancreas: inactivation of the gene leads to massive proteinuria and neonatal deathQ28588477
The long journey through renal filtration: new pieces in the puzzle of slit diaphragm architectureQ33364815
Nineteen novel NPHS1 mutations in a worldwide cohort of patients with congenital nephrotic syndrome (CNS)Q34169609
Role of the polarity protein Scribble for podocyte differentiation and maintenanceQ34269189
Organization of signaling complexes by PDZ-domain scaffold proteinsQ35177318
Nephrin mutations can cause childhood-onset steroid-resistant nephrotic syndromeQ36906056
MAGI-1 Interacts with Nephrin to Maintain Slit Diaphragm Structure through Enhanced Rap1 Activation in PodocytesQ37421404
The podocyte slit diaphragm--from a thin grey line to a complex signalling hub.Q38133715
Podocyte-actin dynamics in health and diseaseQ38940494
MAGI2 Mutations Cause Congenital Nephrotic SyndromeQ39118036
New Insights into Podocyte Biology in Glomerular Health and DiseaseQ39238888
Phosphatidylinositol-3,4,5-trisphosphate regulates the formation of the basolateral plasma membrane in epithelial cellsQ40241493
Bigenic mouse models of focal segmental glomerulosclerosis involving pairwise interaction of CD2AP, Fyn, and synaptopodinQ40289564
Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contactsQ40512855
Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarityQ42009574
Bigenic heterozygosity and the development of steroid-resistant focal segmental glomerulosclerosisQ45746724
MAGI-1 is a component of the glomerular slit diaphragm that is tightly associated with nephrinQ46697366
MAGI-2 is critical for the formation and maintenance of the glomerular filtration barrier in mouse kidney.Q53028656
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectnephrologyQ177635
P304page(s)2362-2371
P577publication date2018-07-13
P1433published inJournal of the American Society of NephrologyQ17123893
P1476titleStructural Basis of Highly Specific Interaction between Nephrin and MAGI1 in Slit Diaphragm Assembly and Signaling
P478volume29

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