| Q42075805 | A High-Content RNAi Screen Identifies Ubiquitin Modifiers That Regulate TNF-Dependent Nuclear Accumulation of NF-κB. |
| Q24652200 | A critical role of RICK/RIP2 polyubiquitination in Nod-induced NF-kappaB activation |
| Q37425442 | A ubiquitin replacement strategy in human cells reveals distinct mechanisms of IKK activation by TNFalpha and IL-1beta. |
| Q26765188 | API2-MALT1 oncoprotein promotes lymphomagenesis via unique program of substrate ubiquitination and proteolysis |
| Q46947690 | Adiponectin suppresses IkappaB kinase activation induced by tumor necrosis factor-alpha or high glucose in endothelial cells: role of cAMP and AMP kinase signaling |
| Q43785411 | Alterations of the IKBKG locus and diseases: an update and a report of 13 novel mutations |
| Q82921238 | Autophagy in innate and adaptive immunity |
| Q36843563 | Beyond tumor necrosis factor receptor: TRADD signaling in toll-like receptors. |
| Q40349474 | Bivalent IAP antagonists, but not monovalent IAP antagonists, inhibit TNF-mediated NF-κB signaling by degrading TRAF2-associated cIAP1 in cancer cells |
| Q39653319 | Blockade of TNFR1 signaling: A role of oscillatory fluid shear stress in osteoblasts |
| Q60045467 | Bypassing drug resistance by triggering necroptosis: recent advances in mechanisms and its therapeutic exploitation in leukemia |
| Q24336952 | CARP-2 is an endosome-associated ubiquitin ligase for RIP and regulates TNF-induced NF-kappaB activation |
| Q35009699 | CYLD deubiquitinates RIP1 in the TNFα-induced necrosome to facilitate kinase activation and programmed necrosis |
| Q37448141 | CYLD: a tumor suppressor deubiquitinase regulating NF-kappaB activation and diverse biological processes |
| Q48277050 | Ca2+-dependent demethylation of phosphatase PP2Ac promotes glucose deprivation-induced cell death independently of inhibiting glycolysis. |
| Q37615916 | Chemical biology of inflammatory cytokine signaling |
| Q37710949 | Chronicles of a death foretold: dual sequential cell death checkpoints in TNF signaling |
| Q38530635 | Cloaked in ubiquitin, a killer hides in plain sight: the molecular regulation of RIPK1. |
| Q37728405 | Cloning and characterization of DULP, a novel ubiquitin-like molecule from human dendritic cells |
| Q39105381 | Complex Pathologic Roles of RIPK1 and RIPK3: Moving Beyond Necroptosis |
| Q40083233 | Construction and application of an avian intestinal intraepithelial lymphocyte cDNA microarray (AVIELA) for gene expression profiling during Eimeria maxima infection. |
| Q39426164 | De-ubiquitinating protease USP2a targets RIP1 and TRAF2 to mediate cell death by TNF. |
| Q37814068 | Deubiquitinases in the regulation of NF-κB signaling |
| Q37184075 | Deubiquitylation and regulation of the immune response |
| Q39285713 | Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling |
| Q46132376 | Dynamic change of TNIK in response to tumor necrosis factor alpha in a TRAF2-dependent manner |
| Q47372738 | Embryonic Lethality and Host Immunity of RelA-Deficient Mice Are Mediated by Both Apoptosis and Necroptosis |
| Q34241279 | Epstein-Barr latent membrane protein 1 transformation site 2 activates NF-κB in the absence of NF-κB essential modifier residues 133–224 or 373–419 |
| Q38803858 | Evidence of necroptosis in hearts subjected to various forms of ischemic insults. |
| Q40235625 | Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma |
| Q21142672 | Expanding the substantial interactome of NEMO using protein microarrays |
| Q26830515 | Fueling the flames: Mammalian programmed necrosis in inflammatory diseases |
| Q62819762 | Function of TRADD in tumor necrosis factor receptor 1 signaling and in TRIF-dependent inflammatory responses |
| Q24678660 | Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-kappaB signaling pathway |
| Q34758473 | Genomic instability causes HGF gene activation in colon cancer cells, promoting their resistance to necroptosis. |
| Q37948116 | How do pleiotropic kinase hubs mediate specific signaling by TNFR superfamily members? |
| Q37987881 | IAPS and ubiquitylation |
| Q39840485 | IKKbeta-mediated nuclear factor-kappaB activation attenuates smac mimetic-induced apoptosis in cancer cells |
| Q29616006 | Identification of RIP1 kinase as a specific cellular target of necrostatins |
| Q50335804 | Identification of TRAF6-dependent NEMO polyubiquitination sites through analysis of a new NEMO mutation causing incontinentia pigmenti |
| Q36637874 | IkappaB kinase complexes: gateways to NF-kappaB activation and transcription |
| Q100395457 | Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death |
| Q93164724 | Insight into the role of p62 in the cisplatin resistant mechanisms of ovarian cancer |
| Q39390897 | Intermediate domain of receptor-interacting protein kinase 1 (RIPK1) determines switch between necroptosis and RIPK1 kinase-dependent apoptosis. |
| Q35108580 | Intertwined pathways of programmed cell death in immunity |
| Q41189574 | JMJD8 is a positive regulator of TNF-induced NF-κB signaling |
| Q90100569 | K63-linked ubiquitination regulates RIPK1 kinase activity to prevent cell death during embryogenesis and inflammation |
| Q34270866 | Kaposi's sarcoma associated herpesvirus encoded viral FLICE inhibitory protein K13 activates NF-κB pathway independent of TRAF6, TAK1 and LUBAC. |
| Q37233180 | Life and death by death receptors |
| Q24641992 | Lys63-linked polyubiquitination of IRAK-1 is required for interleukin-1 receptor- and toll-like receptor-mediated NF-kappaB activation |
| Q33648347 | Lysine 63-linked polyubiquitination of TAK1 at lysine 158 is required for tumor necrosis factor alpha- and interleukin-1beta-induced IKK/NF-kappaB and JNK/AP-1 activation |
| Q35154856 | MALT1-ubiquitination triggers non-genomic NF-κB/IKK signaling upon platelet activation |
| Q24298225 | Malt1 ubiquitination triggers NF-kappaB signaling upon T-cell activation |
| Q26852802 | Membrane trafficking of death receptors: implications on signalling |
| Q35273755 | MicroRNA-500 sustains nuclear factor-κB activation and induces gastric cancer cell proliferation and resistance to apoptosis |
| Q52691052 | Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential. |
| Q38530624 | Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity |
| Q49424017 | Molecular changes associated with increased TNF-α-induced apoptotis in naïve (TN) and central memory (TCM) CD8+ T cells in aged humans |
| Q47843948 | Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. |
| Q38703178 | Molluscum Contagiosum Virus MC159 Abrogates cIAP1-NEMO Interactions and Inhibits NEMO Polyubiquitination. |
| Q36120074 | NEMO inhibits programmed necrosis in an NFκB-independent manner by restraining RIP1. |
| Q37308558 | NEMO/IKKgamma regulates an early NF-kappaB-independent cell-death checkpoint during TNF signaling |
| Q24315489 | NESCA: a new NEMO/IKKgamma and TRAF6 interacting protein |
| Q28271031 | NF-kappaB and the immune response |
| Q37374081 | NF-κB as a Target for Oncogenic Viruses |
| Q35347919 | NF-κB signaling pathways regulated by CARMA family of scaffold proteins |
| Q26822516 | NF-κB, the first quarter-century: remarkable progress and outstanding questions |
| Q38000159 | NFκB and ubiquitination: partners in disarming RIPK1-mediated cell death |
| Q24317458 | NUMBL interacts with TAB2 and inhibits TNFalpha and IL-1beta-induced NF-kappaB activation |
| Q24295288 | NUMBL interacts with TRAF6 and promotes the degradation of TRAF6 |
| Q33788116 | Necroptosis as an alternative form of programmed cell death |
| Q38559586 | Necroptosis: A new way of dying? |
| Q38731479 | Necroptotic cell death in failing heart: relevance and proposed mechanisms |
| Q47336367 | Necrostatin-1 attenuates lipopolysaccharide-induced acute lung injury in mice |
| Q33847645 | Optineurin is required for CYLD-dependent inhibition of TNFα-induced NF-κB activation |
| Q40044695 | Prion protein is required for tumor necrosis factor alpha (TNFα)-triggered nuclear factor kappa B (NF-κB) signaling and cytokine production. |
| Q50095703 | Programmed necrosis in heart disease: Molecular mechanisms and clinical implications |
| Q34924104 | RIP kinases: key decision makers in cell death and innate immunity |
| Q42661602 | RIP1 comes back to life as a cell death regulator in TNFR1 signaling |
| Q42432087 | RIP1 negatively regulates basal autophagic flux through TFEB to control sensitivity to apoptosis |
| Q54976750 | RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors. |
| Q37950926 | RIP1-mediated regulation of lymphocyte survival and death responses |
| Q22001513 | Recruitment of the linear ubiquitin chain assembly complex stabilizes the TNF-R1 signaling complex and is required for TNF-mediated gene induction |
| Q61796844 | Redundant and receptor-specific activities of TRADD, RIPK1 and FADD in death receptor signaling |
| Q39025072 | Regulating the balance between necroptosis, apoptosis and inflammation by inhibitors of apoptosis proteins. |
| Q38222709 | Regulation of NF-κB by TNF family cytokines |
| Q27024099 | Regulation of NF-κB by ubiquitination |
| Q38152946 | Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death |
| Q28262381 | Regulation of tumour necrosis factor signalling: live or let die |
| Q24300455 | Retroviral oncoprotein Tax deregulates NF-kappaB by activating Tak1 and mediating the physical association of Tak1-IKK |
| Q46956935 | Signaling by cell surface death receptors: Alterations in head and neck cancer. |
| Q37340219 | Smac-mimetic-induced epithelial cell death reduces the growth of renal cysts |
| Q52577959 | Smad7 binds to the adaptors TAB2 and TAB3 to block recruitment of the kinase TAK1 to the adaptor TRAF2. |
| Q36189413 | Spy1 induces de-ubiquitinating of RIP1 arrest and confers glioblastoma's resistance to tumor necrosis factor (TNF-α)-induced apoptosis through suppressing the association of CLIPR-59 and CYLD. |
| Q41696945 | THP-1-derived macrophages render lung epithelial cells hypo-responsive to Legionella pneumophila - a systems biology study. |
| Q37948115 | TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer |
| Q24313656 | TNF-alpha induces two distinct caspase-8 activation pathways |
| Q39832953 | TNF-like weak inducer of apoptosis inhibits proinflammatory TNF receptor-1 signaling |
| Q37467736 | TRAF2 must bind to cellular inhibitors of apoptosis for tumor necrosis factor (tnf) to efficiently activate nf-{kappa}b and to prevent tnf-induced apoptosis. |
| Q24300508 | TWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8 |
| Q34540475 | The API2-MALT1 fusion exploits TNFR pathway-associated RIP1 ubiquitination to promote oncogenic NF-κB signaling |
| Q36980637 | The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. |
| Q38255302 | The cell death response to enteropathogenic Escherichia coli infection |
| Q91105567 | The cytokine network involved in the host immune response to periodontitis |
| Q37989135 | The emerging role of linear ubiquitination in cell signaling |
| Q42813292 | The involvement of β-actin in the signaling of transmembrane TNF-α-mediated cytotoxicity |
| Q34021860 | The molecular regulation of programmed necrotic cell injury |
| Q36920268 | The role of TRADD in death receptor signaling |
| Q34118232 | The sequestosome 1/p62 attenuates cytokine gene expression in activated macrophages by inhibiting IFN regulatory factor 8 and TNF receptor-associated factor 6/NF-kappaB activity |
| Q26853682 | The two faces of receptor interacting protein kinase-1 |
| Q36212077 | Tristetraprolin Down-Regulation Contributes to Persistent TNF-Alpha Expression Induced by Cigarette Smoke Extract through a Post-Transcriptional Mechanism |
| Q39296808 | U20 is responsible for human herpesvirus 6B inhibition of tumor necrosis factor receptor-dependent signaling and apoptosis |
| Q39345375 | USP2a negatively regulates IL-1β- and virus-induced NF-κB activation by deubiquitinating TRAF6. |
| Q42809464 | USP4 targets TAK1 to downregulate TNFα-induced NF-κB activation |
| Q37327225 | Ubiquitin in NF-kappaB signaling. |
| Q36946774 | Ubiquitin ligases in cancer: ushers for degradation |
| Q37336094 | Ubiquitin-editing enzyme A20 promotes tolerance to lipopolysaccharide in enterocytes |
| Q36819396 | Ubiquitin-mediated activation of TAK1 and IKK. |
| Q28757756 | Ubiquitination of RIP1 regulates an NF-kappaB-independent cell-death switch in TNF signaling |
| Q90100566 | Ubiquitination of RIPK1 suppresses programmed cell death by regulating RIPK1 kinase activation during embryogenesis |
| Q37424798 | Ubiquitylation in innate and adaptive immunity. |
| Q35781653 | Using Small Molecules to Dissect Non-apoptotic Programmed Cell Death: Necroptosis, Ferroptosis, and Pyroptosis |
| Q27302812 | Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling |
| Q39626529 | c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling |
| Q46557485 | fat facets induces polyubiquitination of Imd and inhibits the innate immune response in Drosophila |
| Q41355717 | p38MAPK/MK2-dependent phosphorylation controls cytotoxic RIPK1 signalling in inflammation and infection |
| Q33873642 | p62/SQSTM1 as an oncotarget mediates cisplatin resistance through activating RIP1-NF-κB pathway in human ovarian cancer cells. |