| P50 | author | Zhao-Xun Liang | Q43020121 |
| | Feiqing Ding | Q56942787 |
| | Huihua Sun | Q57415636 |
| | Zhen Jie Low | Q85341812 |
| P2093 | author name string | Lifeng Yang | |
| | Xuewei Liu | |
| | Ishin Soehano | |
| P2860 | cites work | The type I fatty acid and polyketide synthases: a tale of two megasynthases | Q36489362 |
| | Polyketides, proteins and genes in fungi: programmed nano-machines begin to reveal their secrets | Q36854319 |
| | Engineering fungal nonreducing polyketide synthase by heterologous expression and domain swapping | Q36925570 |
| | Coupled methyl group epimerization and reduction by polyketide synthase ketoreductase domains. Ketoreductase-catalyzed equilibrium isotope exchange | Q37398548 |
| | The structures of type I polyketide synthases | Q38031740 |
| | The structural role of the carrier protein--active controller or passive carrier | Q38038812 |
| | Assembly line polyketide synthases: mechanistic insights and unsolved problems | Q38208037 |
| | Neocarzinostatin naphthoate synthase: an unique iterative type I PKS from neocarzinostatin producer Streptomyces carzinostaticus. | Q38517458 |
| | Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers. | Q39357904 |
| | Hidden function of catalytic domain in 6-methylsalicylic acid synthase for product release | Q40388684 |
| | The biochemical basis for stereochemical control in polyketide biosynthesis | Q41275766 |
| | A fungal ketoreductase domain that displays substrate-dependent stereospecificity | Q41765701 |
| | Stereospecificity of ketoreductase domains of the 6-deoxyerythronolide B synthase | Q42033944 |
| | Combinatorial domain swaps provide insights into the rules of fungal polyketide synthase programming and the rational synthesis of non-native aromatic products | Q42080622 |
| | Sequence, cloning, and analysis of the fluvirucin B1 polyketide synthase from Actinomadura vulgaris | Q42141838 |
| | The crystal structure of the actIII actinorhodin polyketide reductase: proposed mechanism for ACP and polyketide binding | Q42637301 |
| | Engineered biosynthesis of plant polyketides: chain length control in an octaketide-producing plant type III polyketide synthase | Q42666985 |
| | Rational domain swaps decipher programming in fungal highly reducing polyketide synthases and resurrect an extinct metabolite. | Q42726997 |
| | Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases. | Q44552141 |
| | Stereochemistry of catalysis by the ketoreductase activity in the first extension module of the erythromycin polyketide synthase | Q45711194 |
| | The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases. | Q45952293 |
| | A gene (pks2) encoding a putative 6-methylsalicylic acid synthase from Glarea lozoyensis | Q46413076 |
| | Broad substrate specificity of ketoreductases derived from modular polyketide synthases. | Q46924086 |
| | Dynamic docking and electron-transfer between cytochrome b5 and a suite of myoglobin surface-charge mutants. Introduction of a functional-docking algorithm for protein-protein complexes | Q48012070 |
| | Insights into the stereospecificity of ketoreduction in a modular polyketide synthase | Q48530570 |
| | Substrate-dependent stereospecificity of Tyl-KR1: an isolated polyketide synthase ketoreductase domain from Streptomyces fradiae. | Q50987363 |
| | Production of dihydroisocoumarins in Fusarium verticillioides by swapping ketosynthase domain of the fungal iterative polyketide synthase Fum1p with that of lovastatin diketide synthase. | Q51089334 |
| | Dynamic docking and electron transfer between myoglobin and cytochrome b(5). | Q53677708 |
| | Products of the iterative polyketide synthases in 9- and 10-membered enediyne biosynthesis. | Q54393500 |
| | Synthesis of (R)-Mellein by a Partially Reducing Iterative Polyketide Synthase | Q57652673 |
| | Purification and properties of 6-methylsalicylic acid synthase from Penicillium patulum | Q24527376 |
| | A general method of in vitro preparation and specific mutagenesis of DNA fragments: study of protein and DNA interactions | Q24597783 |
| | SWISS-MODEL: An automated protein homology-modeling server | Q24672647 |
| | Structural basis for substrate delivery by acyl carrier protein in the yeast fatty acid synthase | Q27644433 |
| | A tylosin ketoreductase reveals how chirality is determined in polyketides | Q27647542 |
| | The crystal structure of a mammalian fatty acid synthase | Q27651988 |
| | Structural basis for biosynthetic programming of fungal aromatic polyketide cyclization | Q27657897 |
| | Structural and functional analysis of A-type ketoreductases from the amphotericin modular polyketide synthase | Q27663985 |
| | Structural and Biochemical Analyses of Regio- and Stereospecificities Observed in a Type II Polyketide Ketoreductase | Q27667477 |
| | Structural and functional analysis of C2-type ketoreductases from modular polyketide synthases | Q27667844 |
| | Solution Structures of the Acyl Carrier Protein Domain from the Highly Reducing Type I Iterative Polyketide Synthase CalE8 | Q27670442 |
| | Structural and Biochemical Studies of the Hedamycin Type II Polyketide Ketoreductase ( Hed KR): Molecular Basis of Stereo- and Regiospecificities | Q27670915 |
| | Structural Studies of an A2-Type Modular Polyketide Synthase Ketoreductase Reveal Features Controlling α-Substituent Stereochemistry | Q27678573 |
| | Divergence of multimodular polyketide synthases revealed by a didomain structure | Q27679312 |
| | Structural and functional studies of atrans-acyltransferase polyketide assembly line enzyme that catalyzes stereoselective α- and β-ketoreduction | Q27682252 |
| | What makes a protein fold amenable to functional innovation? Fold polarity and stability trade-offs | Q27684324 |
| | Polyketide chain length control by chain length factor | Q28209671 |
| | The neocarzinostatin biosynthetic gene cluster from Streptomyces carzinostaticus ATCC 15944 involving two iterative type I polyketide synthases | Q28242273 |
| | The multifunctional 6-methylsalicylic acid synthase gene of Penicillium patulum. Its gene structure relative to that of other polyketide synthases | Q28253341 |
| | Macromolecular modeling with rosetta | Q29615856 |
| | Emergence of diverse biochemical activities in evolutionarily conserved structural scaffolds of proteins | Q30883445 |
| | Cloning and characterization of a bacterial iterative type I polyketide synthase gene encoding the 6-methylsalicyclic acid synthase. | Q31039601 |
| | 6-MSAS-like polyketide synthase genes occur in lichenized ascomycetes | Q33320093 |
| | Characterization of the azinomycin B biosynthetic gene cluster revealing a different iterative type I polyketide synthase for naphthoate biosynthesis | Q33352595 |
| | Structural similarities between 6-methylsalicylic acid synthase from Penicillium patulum and vertebrate type I fatty acid synthase: evidence from thiol modification studies | Q34398853 |
| | Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms | Q35114475 |
| | Engineering of an "unnatural" natural product by swapping polyketide synthase domains in Aspergillus nidulans | Q35954467 |
| | The biosynthesis, molecular genetics and enzymology of the polyketide-derived metabolites | Q36435230 |
| P433 | issue | 42 | |
| P304 | page(s) | 8542-8549 | |
| P577 | publication date | 2014-11-01 | |
| P1433 | published in | Organic and Biomolecular Chemistry | Q3355939 |
| P1476 | title | Insights into the programmed ketoreduction of partially reducing polyketide synthases: stereo- and substrate-specificity of the ketoreductase domain | |
| P478 | volume | 12 | |