The glymphatic pathway in neurological disorders

scientific article published on 01 November 2018

The glymphatic pathway in neurological disorders is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1474-4422(18)30318-1
P932PMC publication ID6261373
P698PubMed publication ID30353860

P50authorMaiken NedergaardQ15845100
P2093author name stringHumberto Mestre
Martin Kaag Rasmussen
P2860cites workA paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid β.Q24631193
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Paravascular pathways contribute to vasculitis and neuroinflammation after subarachnoid hemorrhage independently of glymphatic controlQ27327474
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Impairment of paravascular clearance pathways in the aging brainQ34577109
Impairment of glymphatic pathway function promotes tau pathology after traumatic brain injuryQ34614529
Biomarkers of traumatic injury are transported from brain to blood via the glymphatic systemQ34946193
UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the ProteasomeQ37214887
Glymphatic fluid transport controls paravascular clearance of AAV vectors from the brainQ37277317
Cerebral arterial pulsation drives paravascular CSF-interstitial fluid exchange in the murine brainQ37399822
Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivationQ37487871
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Cerebrospinal Fluid Clearance in Alzheimer Disease Measured with Dynamic PET.Q38902474
Focal Solute Trapping and Global Glymphatic Pathway Impairment in a Murine Model of Multiple MicroinfarctsQ38966598
Association of Perivascular Localization of Aquaporin-4 With Cognition and Alzheimer Disease in Aging BrainsQ39148351
White matter damage and glymphatic dysfunction in a model of vascular dementia in rats with no prior vascular pathologiesQ40430696
Perivascular spaces, glymphatic dysfunction, and small vessel diseaseQ41493863
Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma.Q41578156
Interstitial solute transport in 3D reconstructed neuropil occurs by diffusion rather than bulk flowQ41687033
Cortical Spreading Depression Closes Paravascular Space and Impairs Glymphatic Flow: Implications for Migraine HeadacheQ41732866
The prelymphatic pathways of the brain as revealed by cervical lymphatic obstruction and the passage of particlesQ41762516
Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI.Q41843877
MRI with intrathecal MRI gadolinium contrast medium administration: a possible method to assess glymphatic function in human brain.Q41872095
Suppression of glymphatic fluid transport in a mouse model of Alzheimer's diseaseQ42364356
The effects of noncoding aquaporin-4 single-nucleotide polymorphisms on cognition and functional progression of Alzheimer's disease.Q42654261
Slow wave sleep disruption increases cerebrospinal fluid amyloid-β levelsQ46170588
Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice.Q46917193
Voluntary running enhances glymphatic influx in awake behaving, young mice.Q47236971
Glymphatic clearance controls state-dependent changes in brain lactate concentrationQ47402970
Paravascular spaces at the brain surface: Low resistance pathways for cerebrospinal fluid flow.Q47437687
Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of deliveryQ47576347
Mechanism of depression as a risk factor in the development of Alzheimer's disease: the function of AQP4 and the glymphatic systemQ47597733
Glymphatic MRI in idiopathic normal pressure hydrocephalusQ47622669
Reduced spinal cord parenchymal cerebrospinal fluid circulation in experimental autoimmune encephalomyelitisQ47645716
The Glymphatic System in Central Nervous System Health and Disease: Past, Present, and FutureQ47806849
Glial scars are permeable to the neurotoxic environment of chronic stroke infarcts.Q47866067
Molecular characterization of perivascular drainage pathways in the murine brain.Q47892833
Astrogliosis and impaired aquaporin-4 and dystrophin systems in idiopathic normal pressure hydrocephalus.Q48000577
A systemic view of Alzheimer disease - insights from amyloid-β metabolism beyond the brainQ48092039
Inspiration is the major regulator of human CSF flow.Q48226918
Subarachnoid hemorrhage - Induced block of cerebrospinal fluid flow: Role of brain coagulation factor III (tissue factor).Q48241472
Why have we not yet developed a simple blood test for TBI?Q48256272
Flow of cerebral interstitial fluid as indicated by the removal of extracellular markers from rat caudate nucleusQ48332620
Omega-3 polyunsaturated fatty acids promote amyloid-β clearance from the brain through mediating the function of the glymphatic systemQ48453375
Impaired glymphatic perfusion after strokes revealed by contrast-enhanced MRI: a new target for fibrinolysis?Q48563729
Impairment of the glymphatic system after diabetesQ48674609
Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic functionQ49292314
The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic' system?Q50048969
Genetic variation in Aquaporin-4 moderates the relationship between sleep and brain Aβ-amyloid burden.Q51767352
Subarachnoid Hemorrhage Severely Impairs Brain Parenchymal Cerebrospinal Fluid Circulation in Nonhuman Primate.Q52094304
β-Amyloid accumulation in the human brain after one night of sleep deprivation.Q52597873
A common mechanism of proteasome impairment by neurodegenerative disease-associated oligomersQ52653236
Amyotrophic Lateral SclerosisQ53750443
The Physiological Roles of Amyloid-β Peptide Hint at New Ways to Treat Alzheimer's Disease.Q55411317
Cellular milieu imparts distinct pathological α-synuclein strains in α-synucleinopathiesQ59066979
Delayed clearance of cerebrospinal fluid tracer from entorhinal cortex in idiopathic normal pressure hydrocephalus: A glymphatic magnetic resonance imaging studyQ87894413
Brain-wide glymphatic enhancement and clearance in humans assessed with MRIQ89575010
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectglymphatic systemQ15474254
P304page(s)1016-1024
P577publication date2018-11-01
P1433published inLancet NeurologyQ15755067
P1476titleThe glymphatic pathway in neurological disorders
P478volume17

Reverse relations

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