KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes

article

KMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.CELREP.2018.09.067
P932PMC publication ID6218204
P698PubMed publication ID30355503

P50authorPietro Lo RisoQ57058932
P2093author name stringVania Broccoli
Robert Jech
Sylvia Boesch
Juliane Winkelmann
Giuseppe Testa
Bernhard Haslinger
Massimiliano Caiazzo
Michael Zech
Sina Atashpaz
Pierre-Luc Germain
Erika Tenderini
Agnieszka D'Antonio-Chronowska
Giulia Barbagiovanni
Adrian Francis Stewart
P2860cites workYY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin DysfunctionQ38432867
Cooperative Binding of Transcription Factors Orchestrates ReprogrammingQ39006802
An improved Flp deleter mouse in C57Bl/6 based on Flpo recombinaseQ39699570
H3K4 Methylation-Dependent Memory of Somatic Cell Identity Inhibits Reprogramming and Development of Nuclear Transfer EmbryosQ40985261
Rapid Chromatin Switch in the Direct Reprogramming of Fibroblasts to NeuronsQ42379954
KMT2A and KMT2B Mediate Memory Function by Affecting Distinct Genomic Regions.Q42777129
Definitive hematopoiesis requires the mixed-lineage leukemia geneQ44805187
The epigenetic factor Kmt2a/Mll1 regulates neural progenitor proliferation and neuronal and glial differentiationQ47074146
Mutations in the histone methyltransferase gene KMT2B cause complex early-onset dystonia.Q47849142
A reliable lacZ expression reporter cassette for multipurpose, knockout-first allelesQ47867233
The histone methyltransferase Wbp7 controls macrophage function through GPI glycolipid anchor synthesisQ47932561
Histone-methyltransferase MLL2 (KMT2B) is required for memory formation in mice.Q48155491
Clinical exome sequencing in early-onset generalized dystonia and large-scale resequencing follow-upQ48788624
Not All H3K4 Methylations Are Created Equal: Mll2/COMPASS Dependency in Primordial Germ Cell Specification.Q50217919
Molecular analyses of patients with hyperferritinemia and normal serum iron values reveal both L ferritin IRE and 3 new ferroportin (slc11A3) mutationsQ50335666
Mll2 is required for H3K4 trimethylation on bivalent promoters in embryonic stem cells, whereas Mll1 is redundant.Q50695883
A de novo paradigm for mental retardation.Q51828800
Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferasesQ24305587
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locusQ24313196
Direct conversion of fibroblasts to functional neurons by defined factorsQ24641912
Analysis of protein-coding genetic variation in 60,706 humansQ26831376
Multiple epigenetic maintenance factors implicated by the loss of Mll2 in mouse developmentQ28587425
Hierarchical mechanisms for direct reprogramming of fibroblasts to neuronsQ29871108
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fatesQ29871111
Myogenic lineage determination and differentiation: evidence for a regulatory gene pathwayQ30462236
Increased apoptosis and skewed differentiation in mouse embryonic stem cells lacking the histone methyltransferase Mll2.Q30479488
De Novo variants in the KMT2A (MLL) gene causing atypical Wiedemann-Steiner syndrome in two unrelated individuals identified by clinical exome sequencingQ33812098
Comprehensive functional annotation of 18 missense mutations found in suspected hemochromatosis type 4 patientsQ34414345
Integrative Analyses of Human Reprogramming Reveal Dynamic Nature of Induced PluripotencyQ35880090
Familial cortical myoclonus with a mutation in NOL3.Q36200469
Dissecting direct reprogramming from fibroblast to neuron using single-cell RNA-seqQ37056065
Chromatin remodelling factor Mll1 is essential for neurogenesis from postnatal neural stem cellsQ37238475
Haploinsufficiency of KMT2B, Encoding the Lysine-Specific Histone Methyltransferase 2B, Results in Early-Onset Generalized DystoniaQ37480675
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)988-1001
P577publication date2018-10-01
P1433published inCell ReportsQ5058165
P1476titleKMT2B Is Selectively Required for Neuronal Transdifferentiation, and Its Loss Exposes Dystonia Candidate Genes
P478volume25