Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis

scientific article published on 19 October 2018

Loss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41419-018-0901-6
P932PMC publication ID6195598
P698PubMed publication ID30341279

P50authorDenny L CottleQ42755641
Sebastian DworkinQ42799609
Charbel DaridoQ58876642
P2093author name stringAlana Auden
Seema Srivastava
Stephen M Jane
Ian M Smyth
Fiona H Tan
Stephen J Goldie
Rhys Brady
Suraya Roslan
Darren D Partridge
P2860cites workMolecular cloning of a novel T cell-directed CC chemokine expressed in thymus by signal sequence trap using Epstein-Barr virus vectorQ24312084
Epidermal wound repair is regulated by the planar cell polarity signaling pathwayQ24339352
The CC chemokines MDC and TARC induce platelet activation via CCR4Q28177034
The T cell-directed CC chemokine TARC is a highly specific biological ligand for CC chemokine receptor 4Q28239606
Thymus and activation regulated chemokine (TARC)/CCL17 and skin diseasesQ28253402
The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4Q28505730
A homolog of Drosophila grainy head is essential for epidermal integrity in miceQ28585220
A GRHL3-regulated repair pathway suppresses immune-mediated epidermal hyperplasiaQ28587867
Identification of a Novel Proto-oncogenic Network in Head and Neck Squamous Cell CarcinomaQ28834533
Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet functionQ30306721
Mesalamine blocks tumor necrosis factor growth inhibition and nuclear factor kappaB activation in mouse colonocytesQ30638019
Thymus and activation-regulated chemokine in atopic dermatitis: Serum thymus and activation-regulated chemokine level is closely related with disease activityQ32156624
Tumor formation initiated by nondividing epidermal cells via an inflammatory infiltrateQ34358943
Clinical significance of serum thymus and activation-regulated chemokine in gastric cancer: potential as a serum biomarker.Q35713297
The cornified envelope: a model of cell death in the skinQ36085605
Chemokine CCL17 induced by hypoxia promotes the proliferation of cervical cancer cellQ36309396
Stem cells behind the barrier.Q38118084
Thymus and activation-regulated chemokine as a clinical biomarker in atopic dermatitisQ38195864
Epidermal barrier in hereditary ichthyoses, atopic dermatitis, and psoriasis.Q38619156
Two Ancient Gene Families Are Critical for Maintenance of the Mammalian Skin Barrier in Postnatal Life.Q38786479
The role of barrier genes in epidermal malignancyQ38797349
A Th2 chemokine, TARC, produced by keratinocytes may recruit CLA+CCR4+ lymphocytes into lesional atopic dermatitis skin.Q40853609
Tumor-associated macrophage or chemokine ligand CCL17 positively regulates the tumorigenesis of hepatocellular carcinomaQ40968092
Inhibition of binding of interferon-gamma to its receptor by salicylates used in inflammatory bowel diseaseQ41599875
Fetal inhibition of inflammation improves disease phenotypes in harlequin ichthyosis.Q41744100
Sox2 modulates the function of two distinct cell lineages in mouse skinQ42001929
Stratum corneum TARC level is a new indicator of lesional skin inflammation in atopic dermatitis.Q43107214
Thymus and activation-regulated chemokine (TARC/CCL17) in mycosis fungoides: serum TARC levels reflect the disease activity of mycosis fungoidesQ44274756
Targeting of the tumor suppressor GRHL3 by a miR-21-dependent proto-oncogenic network results in PTEN loss and tumorigenesis.Q48054446
Pigmented purpuric dermatitis with high expression levels of serum TARC/CCL17 and epidermal TSLP.Q54646998
PsoriasisQ58235916
Potential role of the chemokine receptors CXCR3, CCR4, and the integrin alphaEbeta7 in the pathogenesis of psoriasis vulgarisQ73778362
TARC, a CC chemokine, is frequently expressed in classic Hodgkin's lymphoma but not in NLP Hodgkin's lymphoma, T-cell-rich B-cell lymphoma, and most cases of anaplastic large cell lymphomaQ74071941
Presence of high contents of thymus and activation-regulated chemokine in platelets and elevated plasma levels of thymus and activation-regulated chemokine and macrophage-derived chemokine in patients with atopic dermatitisQ74445337
Differential expression of thymus and activation regulated chemokine and its receptor CCR4 in nodal and cutaneous anaplastic large-cell lymphomas and Hodgkin's diseaseQ74615775
CCL17 transgenic mice show an enhanced Th2-type response to both allergic and non-allergic stimuliQ79951348
Serum levels of thymus and activation-regulated chemokine can be used in the clinical evaluation of atopic dermatitisQ85458810
Serum thymus and activation-regulated chemokine as disease activity and response biomarker in alopecia areataQ86489325
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
cell biologyQ7141
keratinocyteQ1473931
cancer researchQ3421914
P304page(s)1072
P577publication date2018-10-19
P1433published inCell Death and DiseaseQ2197222
P1476titleLoss of GRHL3 leads to TARC/CCL17-mediated keratinocyte proliferation in the epidermis
P478volume9

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cites work (P2860)
Q91739345Skin transcriptome profiling of Changthangi goats highlights the relevance of genes involved in Pashmina production
Q91795960Targeted Therapy Against the Cell of Origin in Cutaneous Squamous Cell Carcinoma
Q104136822Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis

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