scholarly article | Q13442814 |
P2093 | author name string | Volker Neugebauer | |
Sabatino Maione | |||
Enza Palazzo | |||
Mariacristina Mazzitelli | |||
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Selective actions of novel allosteric modulators reveal functional heteromers of metabotropic glutamate receptors in the CNS | Q24629746 | ||
Group II Metabotropic Glutamate Receptors as Targets for Novel Antipsychotic Drugs | Q26744729 | ||
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Glutamate stimulates inositol phosphate formation in striatal neurones | Q28282165 | ||
Local administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in peripheral pain in rats | Q28284443 | ||
Antinociceptive effect of a group II metabotropic glutamate receptor antagonist in the thalamus of monoarthritic rats | Q28509028 | ||
Allosteric modulation of metabotropic glutamate receptors | Q30448534 | ||
Metabotropic glutamate receptors: from the workbench to the bedside | Q30448778 | ||
NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation | Q30459203 | ||
Metabotropic glutamate receptor 3 activation is required for long-term depression in medial prefrontal cortex and fear extinction | Q30619467 | ||
A family of metabotropic glutamate receptors | Q31159811 | ||
Targeting metabotropic glutamate receptors for novel treatments of schizophrenia | Q33604654 | ||
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Astrocytes modulate thalamic sensory processing via mGlu2 receptor activation | Q33825054 | ||
Cognitive impairment in pain through amygdala-driven prefrontal cortical deactivation | Q33843541 | ||
Metabotropic glutamate 2 receptor potentiators: receptor modulation, frequency-dependent synaptic activity, and efficacy in preclinical anxiety and psychosis model(s). | Q34395427 | ||
The functional GRM3 Kozak sequence variant rs148754219 affects the risk of schizophrenia and alcohol dependence as well as bipolar disorder | Q34430082 | ||
Functional plasticity of group II metabotropic glutamate receptors in regulating spinal excitatory and inhibitory synaptic input in neuropathic pain | Q34458565 | ||
mGlu2 metabotropic glutamate receptors restrain inflammatory pain and mediate the analgesic activity of dual mGlu2/mGlu3 receptor agonists | Q34537679 | ||
Enhanced group II mGluR-mediated inhibition of pain-related synaptic plasticity in the amygdala | Q34646328 | ||
CB1 augments mGluR5 function in medial prefrontal cortical neurons to inhibit amygdala hyperactivity in an arthritis pain model | Q34889241 | ||
Activation of metabotropic glutamate (mGlu)2 receptors suppresses histamine release in limbic brain regions following acute ketamine challenge | Q35015464 | ||
Metabotropic glutamate receptor involvement in models of acute and persistent pain: prospects for the development of novel analgesics | Q35137409 | ||
Group II metabotropic glutamate receptors (mGlu2/3) in drug addiction | Q35154064 | ||
N-acetyl-cysteine, a drug that enhances the endogenous activation of group-II metabotropic glutamate receptors, inhibits nociceptive transmission in humans | Q35232882 | ||
Group II mGluRs modulate baseline and arthritis pain-related synaptic transmission in the rat medial prefrontal cortex | Q35738531 | ||
The amygdala and persistent pain | Q35779153 | ||
Palmitoylethanolamide reduces pain-related behaviors and restores glutamatergic synapses homeostasis in the medial prefrontal cortex of neuropathic mice. | Q35939665 | ||
Epigenetic upregulation of metabotropic glutamate receptor 2 in the spinal cord attenuates oestrogen-induced visceral hypersensitivity | Q36037658 | ||
Amygdala pain mechanisms | Q36430485 | ||
Rescue of Impaired mGluR5-Driven Endocannabinoid Signaling Restores Prefrontal Cortical Output to Inhibit Pain in Arthritic Rats | Q36480259 | ||
Glutamate receptor ligands. | Q36646018 | ||
Discovery of a Selective and CNS Penetrant Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 3 with Antidepressant and Anxiolytic Activity in Rodents | Q36733346 | ||
Serotonin 2A Receptor SNP rs7330461 Association with Treatment Response to Pomaglumetad Methionil in Patients with Schizophrenia | Q36735985 | ||
Forebrain pain mechanisms | Q37238581 | ||
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders | Q37360436 | ||
The glutamate homeostasis hypothesis of addiction | Q37538517 | ||
Metabotropic glutamate receptors: physiology, pharmacology, and disease | Q37670222 | ||
"Molecular switches" on mGluR allosteric ligands that modulate modes of pharmacology | Q37845809 | ||
Metabotropic glutamate receptors as targets for analgesia: antagonism, activation, and allosteric modulation | Q37861794 | ||
Metabotropic glutamate receptors and the control of chronic pain | Q37951164 | ||
Recent progress in the synthesis and characterization of group II metabotropic glutamate receptor allosteric modulators. | Q38031831 | ||
Therapeutic potential of targeting metabotropic glutamate receptors for Parkinson's disease | Q38092819 | ||
Block of theta-burst-induced long-term potentiation by (1S,3S)-1-aminocyclopentane-1,3-dicarboxylic acid: further evidence against long-term potentiation as a model for learning. | Q52192763 | ||
Metabotropic Glutamate Receptor 2/3 (mGluR2/3) Activation Suppresses TRPV1 Sensitization in Mouse, But Not Human, Sensory Neurons. | Q55114683 | ||
Periaqueductal gray matter metabotropic glutamate receptors modulate formalin-induced nociception | Q73487783 | ||
Group II mGluR receptor agonists are effective in persistent and neuropathic pain models in rats | Q74461047 | ||
Peripheral group II metabotropic glutamate receptors mediate endogenous anti-allodynia in inflammation | Q79349616 | ||
Distribution of metabotropic glutamate 2 and 3 receptors in the rat forebrain: Implication in emotional responses and central disinhibition | Q80613698 | ||
Exploratory analysis for a targeted patient population responsive to the metabotropic glutamate 2/3 receptor agonist pomaglumetad methionil in schizophrenia | Q87147412 | ||
Pathway-Specific Alterations of Cortico-Amygdala Transmission in an Arthritis Pain Model | Q88306394 | ||
Role of the Prefrontal Cortex in Pain Processing | Q89018093 | ||
Progress toward advanced understanding of metabotropic glutamate receptors: structure, signaling and therapeutic indications | Q38209092 | ||
Metabotropic glutamate receptors as drug targets: what's new? | Q38288449 | ||
mGluRs head to toe in pain. | Q38368341 | ||
Modulation of Chronic Pain by Metabotropic Glutamate Receptors | Q38751831 | ||
In vitro pharmacological and rat pharmacokinetic characterization of LY3020371, a potent and selective mGlu2/3 receptor antagonist | Q38805426 | ||
N-acetylaspartylglutamate is an agonist at mGluR₃ in vivo and in vitro | Q38833017 | ||
A role for the locus coeruleus in the analgesic efficacy of N-acetylaspartylglutamate peptidase (GCPII) inhibitors ZJ43 and 2-PMPA. | Q38887993 | ||
NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication. | Q38912835 | ||
Activation of mGlu3 metabotropic glutamate receptors enhances GDNF and GLT-1 formation in the spinal cord and rescues motor neurons in the SOD-1 mouse model of amyotrophic lateral sclerosis. | Q38936901 | ||
Group II/III metabotropic glutamate receptors exert endogenous activity-dependent modulation of TRPV1 receptors on peripheral nociceptors | Q38970519 | ||
N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a lin | Q39643947 | ||
Group II metabotropic glutamate receptor activation attenuates peripheral sensitization in inflammatory states | Q39846823 | ||
Antinociceptive effects of N-acetylaspartylglutamate (NAAG) peptidase inhibitors ZJ-11, ZJ-17 and ZJ-43 in the rat formalin test and in the rat neuropathic pain model | Q40539364 | ||
Comparative effect of L-CCG-I, DCG-IV and gamma-carboxy-L-glutamate on all cloned metabotropic glutamate receptor subtypes. | Q40991782 | ||
Group II mGluRs suppress hyperexcitability in mouse and human nociceptors | Q41699835 | ||
N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors. | Q41843975 | ||
Activation of group 2 metabotropic glutamate receptors reduces behavioral and electrographic correlates of pilocarpine induced status epilepticus | Q42006202 | ||
Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model. | Q42065018 | ||
Intracerebroventricular administration of N-acetylaspartylglutamate (NAAG) peptidase inhibitors is analgesic in inflammatory pain | Q42397202 | ||
CNS distribution of metabotropic glutamate 2 and 3 receptors: transgenic mice and [³H]LY459477 autoradiography | Q43622729 | ||
L-Acetylcarnitine induces analgesia by selectively up-regulating mGlu2 metabotropic glutamate receptors | Q43964695 | ||
Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. | Q44085153 | ||
Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression. | Q44978632 | ||
mGlu and NMDA receptor contributions to capsaicin-induced thermal and mechanical hypersensitivity | Q45274101 | ||
Targeting group II metabotropic glutamate (mGlu) receptors for the treatment of psychosis associated with Alzheimer's disease: selective activation of mGlu2 receptors amplifies beta-amyloid toxicity in cultured neurons, whereas dual activation of mG | Q45356884 | ||
Antinociceptive synergistic effect of spinal mGluR2/3 antagonist and glial cells inhibitor on peripheral inflammation-induced mechanical hypersensitivity | Q45836667 | ||
Epigenetic modulation of mGlu2 receptors by histone deacetylase inhibitors in the treatment of inflammatory pain | Q46102945 | ||
Amygdala Plasticity and Pain | Q47109472 | ||
Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system | Q47402524 | ||
Modulation of sensory inhibition in the ventrobasal thalamus via activation of group II metabotropic glutamate receptors by 2R,4R-aminopyrrolidine-2,4-dicarboxylate | Q47718843 | ||
Design and Synthesis of mGlu2 NAMs with Improved Potency and CNS Penetration Based on a Truncated Picolinamide Core | Q47758525 | ||
Inflammation alters the effects of mGlu receptor agonists on spinal nociceptive neurones | Q47882699 | ||
Characterisation of mGluRs which modulate nociception in the PAG of the mouse | Q48307145 | ||
Broad spectrum efficacy with LY2969822, an oral prodrug of metabotropic glutamate 2/3 receptor agonist LY2934747, in rodent pain models | Q48318347 | ||
Differential changes of group II and group III mGluR function in central amygdala neurons in a model of arthritic pain | Q48506273 | ||
Group I metabotropic glutamate receptors activate the p70S6 kinase via both mammalian target of rapamycin (mTOR) and extracellular signal-regulated kinase (ERK 1/2) signaling pathways in rat striatal and hippocampal synaptoneurosomes | Q48611826 | ||
Positive allosteric modulation reveals a specific role for mGlu2 receptors in sensory processing in the thalamus. | Q48747858 | ||
Groups II and III metabotropic glutamate receptors differentially modulate brief and prolonged nociception in primate STT cells | Q49162350 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | molecular biology | Q7202 |
P304 | page(s) | 383 | |
P577 | publication date | 2018-01-01 | |
P1433 | published in | Frontiers in Molecular Neuroscience | Q27721913 |
P1476 | title | Group II Metabotropic Glutamate Receptors: Role in Pain Mechanisms and Pain Modulation | |
P478 | volume | 11 |
Q60958735 | Tarsal Tunnel Mechanosensitivity Is Increased in Patients with Asthma: A Case-Control Study | cites work | P2860 |
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