scholarly article | Q13442814 |
P356 | DOI | 10.1586/14737159.2015.976557 |
P698 | PubMed publication ID | 25370828 |
P50 | author | Josephine C. Adams | Q52087156 |
P2093 | author name string | Josephine C Adams | |
P2860 | cites work | Cancer genome landscapes | Q22242276 |
Migrastatin analogues target fascin to block tumour metastasis | Q24306715 | ||
Tumor self-seeding by circulating cancer cells | Q24658224 | ||
Interaction of fascin and protein kinase Calpha: a novel intersection in cell adhesion and motility | Q24680112 | ||
Fascin, an actin-bundling protein, modulates colonic epithelial cell invasiveness and differentiation in vitro | Q24684410 | ||
Actin structure-dependent stepping of myosin 5a and 10 during processive movement | Q27306218 | ||
Structure, evolutionary conservation, and conformational dynamics of Homo sapiens fascin-1, an F-actin crosslinking protein | Q27661102 | ||
Mechanism of Actin Filament Bundling by Fascin | Q27670479 | ||
Molecular Mechanism of Fascin Function in Filopodial Formation | Q27675250 | ||
Fascin, a novel target of beta-catenin-TCF signaling, is expressed at the invasive front of human colon cancer | Q28237051 | ||
Naturally occurring antibodies devoid of light chains | Q28269589 | ||
Fascins, a family of actin bundling proteins | Q28282915 | ||
Actinin-4 increases cell motility and promotes lymph node metastasis of colorectal cancer | Q28506447 | ||
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression | Q28595042 | ||
Mechanism of filopodia initiation by reorganization of a dendritic network | Q29616648 | ||
Stratifying fascin and cortactin function in invadopodium formation using inhibitory nanobodies and targeted subcellular delocalization | Q30009497 | ||
Fascin regulates chronic inflammation-related human colon carcinogenesis by inhibiting cell anoikis | Q39020527 | ||
The formin Daam1 and fascin directly collaborate to promote filopodia formation. | Q39126569 | ||
The actin-bundling protein fascin is overexpressed in colorectal adenomas and promotes motility in adenoma cells in vitro | Q39801876 | ||
Rac regulates the interaction of fascin with protein kinase C in cell migration | Q39948787 | ||
A novel form of motility in filopodia revealed by imaging myosin-X at the single-molecule level | Q41978648 | ||
Self-assembly of filopodia-like structures on supported lipid bilayers | Q42360649 | ||
Directional transport by nonprocessive motor proteins on fascin-cross-linked actin arrays | Q43743089 | ||
The filamentous actin cross-linking/bundling activity of mammalian formins. | Q46331574 | ||
In colon carcinogenesis, the cytoskeletal protein gelsolin is down-regulated during the transition from adenoma to carcinoma. | Q53318985 | ||
PTEN loss and KRAS activation leads to the formation of serrated adenomas and metastatic carcinoma in the mouse intestine. | Q54393310 | ||
A novel Rho-dependent pathway that drives interaction of fascin-1 with p-Lin-11/Isl-1/Mec-3 kinase (LIMK) 1/2 to promote fascin-1/actin binding and filopodia stability. | Q30424110 | ||
Dual actin-bundling and protein kinase C-binding activities of fascin regulate carcinoma cell migration downstream of Rac and contribute to metastasis | Q30480311 | ||
Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin | Q30574577 | ||
Cofilin cooperates with fascin to disassemble filopodial actin filaments | Q30581893 | ||
Prognostic significance of fascin expression in advanced colorectal cancer: an immunohistochemical study of colorectal adenomas and adenocarcinomas | Q33259830 | ||
Fascin-1 promoter activity is regulated by CREB and the aryl hydrocarbon receptor in human carcinoma cells | Q33425930 | ||
Association of the actin-binding protein transgelin with lymph node metastasis in human colorectal cancer | Q33499383 | ||
MicroRNA-145 inhibits tumour growth and metastasis in colorectal cancer by targeting fascin-1. | Q33555201 | ||
Stress-induced cleavage of Myc promotes cancer cell survival | Q33588071 | ||
Epithelial-to-mesenchymal transition and the cancer stem cell phenotype: insights from cancer biology with therapeutic implications for colorectal cancer | Q33700204 | ||
The actin-bundling protein fascin is overexpressed in inflammatory bowel disease and may be important in tissue repair | Q33827631 | ||
Actin, microtubules, and vimentin intermediate filaments cooperate for elongation of invadopodia | Q33840016 | ||
A cell-based fascin bioassay identifies compounds with potential anti-metastasis or cognition-enhancing functions. | Q34392217 | ||
Recent findings on the health effects of omega-3 fatty acids and statins, and their interactions: do statins inhibit omega-3? | Q34536800 | ||
Rifaximin-mediated changes to the epithelial cell proteome: 2-D gel analysis | Q34901665 | ||
Emergence of potent inhibitors of metastasis in lung cancer via syntheses based on migrastatin. | Q35217165 | ||
Colon-specific tumorigenesis in mice driven by Cre-mediated inactivation of Apc and activation of mutant Kras | Q35565497 | ||
Review article: colorectal carcinoma and inflammatory bowel disease | Q35880374 | ||
Fascin promotes filopodia formation independent of its role in actin bundling | Q35962314 | ||
MicroRNAs and other non-coding RNAs as targets for anticancer drug development | Q35994443 | ||
Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42 | Q36328771 | ||
Myosin VI has a one track mind versus myosin Va when moving on actin bundles or at an intersection | Q36542334 | ||
Independent prognostic value of fascin immunoreactivity in stage III-IV colonic adenocarcinoma | Q36610155 | ||
Fascin-1 is a novel biomarker of aggressiveness in some carcinomas | Q36766973 | ||
The prometastatic ribosomal S6 kinase 2-cAMP response element-binding protein (RSK2-CREB) signaling pathway up-regulates the actin-binding protein fascin-1 to promote tumor metastasis | Q37289259 | ||
Overexpression of fascin-1 in advanced colorectal adenocarcinoma: tissue microarray analysis of immunostaining scores with clinicopathological parameters | Q37363722 | ||
The roles of fascins in health and disease | Q37880684 | ||
Developmental pathways in colon cancer: crosstalk between WNT, BMP, Hedgehog and Notch | Q38049051 | ||
What are the best routes to effectively model human colorectal cancer? | Q38087005 | ||
Is availability of anti-EGFR therapy for the colorectal adenocarcinomas showing fascin expression limited? | Q38397212 | ||
Prognostic Impact of Fascin-1 Expression is More Significant in Advanced Colorectal Cancer | Q38481579 | ||
Characterization of cell-matrix adhesion requirements for the formation of fascin microspikes | Q38614984 | ||
Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion. | Q38976962 | ||
Fascin plays a role in stress fiber organization and focal adhesion disassembly. | Q38984596 | ||
P433 | issue | 1 | |
P921 | main subject | colorectal cancer | Q188874 |
biomarker | Q864574 | ||
colorectal carcinoma | Q25493920 | ||
P304 | page(s) | 41-48 | |
P577 | publication date | 2014-11-05 | |
P1433 | published in | Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare | Q15756305 |
P1476 | title | Fascin-1 as a biomarker and prospective therapeutic target in colorectal cancer | |
P478 | volume | 15 |
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Q38750488 | Fascin Regulates Nuclear Movement and Deformation in Migrating Cells |
Q89771439 | Investigation of promoter methylation of FSCN1 gene and FSCN1 protein expression in differentiated thyroid carcinomas |
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