Effect of combining rosiglitazone with either metformin or insulin on β-cell mass and function in an animal model of Type 2 diabetes characterized by reduced β-cell mass at birth

scientific article published on 01 March 2011

Effect of combining rosiglitazone with either metformin or insulin on β-cell mass and function in an animal model of Type 2 diabetes characterized by reduced β-cell mass at birth is …
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scholarly articleQ13442814

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P356DOI10.1111/J.1753-0407.2010.00101.X
P698PubMed publication ID21040499

P50authorHertzel C. GersteinQ41696958
Alison C HollowayQ88451199
P2093author name stringBart P Hettinga
P2860cites workInsulin analogues display IGF-I-like mitogenic and anti-apoptotic activities in cultured cancer cellsQ39895082
Metformin restores insulin secretion altered by chronic exposure to free fatty acids or high glucose: a direct metformin effect on pancreatic beta-cellsQ42490936
Rosiglitazone improves pancreatic mitochondrial function in an animal model of dysglycemia: role of the insulin-like growth factor axisQ42853592
Low-dose combination therapy with rosiglitazone and metformin to prevent type 2 diabetes mellitus (CANOE trial): a double-blind randomised controlled studyQ42982910
Beta-cell mass dynamics in Zucker diabetic fatty rats. Rosiglitazone prevents the rise in net cell deathQ43596005
Biotransformation of insulin glargine after subcutaneous injection in healthy subjectsQ44379874
Specific and Combined Effects of Insulin and Glucose on Functional Pancreatic β-Cell Mass in Vivo in Adult RatsQ44440569
Reduced β-cell mass and altered glucose sensing impair insulin-secretory function in βIRKO miceQ44602874
Pioglitazone improves insulin secretory capacity and prevents the loss of beta-cell mass in obese diabetic db/db mice: Possible protection of beta cells from oxidative stressQ44815359
Rosiglitazone prevents diabetes by increasing beta-cell mass in an animal model of type 2 diabetes characterized by reduced beta-cell mass at birthQ46923573
Effect of chronic rosiglitazone, metformin and glyburide treatment on beta-cell mass, function and insulin sensitivity in mZDF ratsQ46923579
Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp.Q51561183
Fetal and neonatal nicotine exposure and postnatal glucose homeostasis: identifying critical windows of exposure.Q51748986
Type 2 diabetes-a matter of beta-cell life and death?Q53873519
Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients.Q53979441
Selective β-Cell Loss and α-Cell Expansion in Patients with Type 2 Diabetes Mellitus in KoreaQ57214866
Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or MetforminQ22250892
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetesQ29619192
Glycemic control promotes pancreatic beta-cell regeneration in streptozotocin-induced diabetic miceQ33525549
In vitro metabolic and mitogenic signaling of insulin glargine and its metabolitesQ33537987
The role of insulin-like growth factor-I and its binding proteins in glucose homeostasis and type 2 diabetesQ34127704
Effects of withdrawal from metformin on the development of diabetes in the diabetes prevention programQ34335544
The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of Type 2 diabetesQ35085591
Development of the endocrine pancreasQ36253123
Growth factors and beta cell replication.Q36259876
Regulation of pancreatic beta-cell massQ36267776
Animal models of type 2 diabetes with reduced pancreatic beta-cell massQ36298862
Intrinsic regulators of pancreatic beta-cell proliferationQ36528824
On the role of IRS2 in the regulation of functional beta-cell massQ36576524
P433issue1
P921main subjectmetforminQ19484
(RS)-rosiglitazoneQ424771
type 2 diabetesQ3025883
P304page(s)74-81
P577publication date2011-03-01
P1433published inJournal of diabetesQ27020371
P1476titleEffect of combining rosiglitazone with either metformin or insulin on β-cell mass and function in an animal model of Type 2 diabetes characterized by reduced β-cell mass at birth
P478volume3