Lnx2b, an E3 ubiquitin ligase, in dorsal forerunner cells and Kupffer's vesicle is required for specification of zebrafish left–right laterality

Lnx2b, an E3 ubiquitin ligase, in dorsal forerunner cells and Kupffer's vesicle is required for specification of zebrafish left–right laterality is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1080/19768354.2014.968205

P2093author name stringMin Jung Kim
Myungchull Rhee
Hyunju Ro
P2860cites workCalcium fluxes in dorsal forerunner cells antagonize beta-catenin and alter left-right patterning.Q51971085
Mice with mutations in Mahogunin ring finger-1 (Mgrn1) exhibit abnormal patterning of the left-right axis.Q52003130
Ubiquitin proteasome system networks in the neurological disordersQ58269554
p53 activation by knockdown technologiesQ21563456
Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor proteinQ22008584
Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafishQ24306370
LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradationQ24536102
RING domain E3 ubiquitin ligasesQ27860546
Lnx-2b restricts gsc expression to the dorsal mesoderm by limiting Nodal and Bozozok activityQ28312158
Organizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-likeQ28312167
Cell autonomous regulation of multiple Dishevelled-dependent pathways by mammalian NkdQ28507761
The ion channel polycystin-2 is required for left-right axis determination in miceQ28508558
The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNXQ28509667
Vertebrate proteins related to Drosophila Naked Cuticle bind Dishevelled and antagonize Wnt signalingQ28591110
Two populations of node monocilia initiate left-right asymmetry in the mouseQ29617071
Ubiquitin and ubiquitin-like proteins as multifunctional signalsQ30014838
Kupffer's vesicle is a ciliated organ of asymmetry in the zebrafish embryo that initiates left-right development of the brain, heart and gut.Q31147995
Zebrafish Nkd1 promotes Dvl degradation and is required for left-right patterningQ34139282
The Cerberus/Dan-family protein Charon is a negative regulator of Nodal signaling during left-right patterning in zebrafishQ34313532
Proteomics strategy to identify substrates of LNX, a PDZ domain-containing E3 ubiquitin ligaseQ34378600
Transgenic analysis of the physiological functions of Mahogunin Ring Finger-1 isoformsQ34564123
Zebrafish Naked1 and Naked2 antagonize both canonical and non-canonical Wnt signalingQ34661534
Human laterality disordersQ36388233
Left-right asymmetry in the vertebrate embryo: from early information to higher-level integrationQ36423913
Role of ubiquitin- and Ubl-binding proteins in cell signalingQ36736630
Use of FOXJ1CreER2T mice for inducible deletion of embryonic node gene expressionQ37154405
Mechanisms and function of substrate recruitment by F-box proteins.Q37307464
Left-right asymmetry in zebrafishQ38004929
A novel PTB-PDZ domain interaction mediates isoform-specific ubiquitylation of mammalian NumbQ40584703
Restricted expression of cardiac myosin genes reveals regulated aspects of heart tube assembly in zebrafish.Q40797201
Mahogunin-mediated α-tubulin ubiquitination via noncanonical K6 linkage regulates microtubule stability and mitotic spindle orientationQ42003170
FGF-induced vesicular release of Sonic hedgehog and retinoic acid in leftward nodal flow is critical for left-right determination.Q46486386
Distinct functions of Wnt/beta-catenin signaling in KV development and cardiac asymmetryQ47073083
The zebrafishnodal-related genesouthpawis required for visceral and diencephalic left-right asymmetryQ47073169
The T box transcription factor no tail in ciliated cells controls zebrafish left-right asymmetry.Q47765648
Abnormal nodal flow precedes situs inversus in iv and inv miceQ51049412
P433issue5
P304page(s)333-339
P577publication date2014-09-03
P1433published inAnimal Cells and SystemsQ15754776
P1476titleLnx2b, an E3 ubiquitin ligase, in dorsal forerunner cells and Kupffer's vesicle is required for specification of zebrafish left–right laterality
P478volume18

Reverse relations

Q58133758Ubiquitin conjugation system for body axes specification in vertebratescites workP2860

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