The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy

scientific article published on 17 October 2018

The IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1107686364
P356DOI10.1186/S12974-018-1330-2
P932PMC publication ID6192101
P698PubMed publication ID30333036

P50authorYiwei ChuQ88638221
P2093author name stringBo Wang
Chen Wang
Ronghua Liu
Chujun Zhao
Jiao Yang
Feifei Luo
Jiawen Qian
Yuedi Wang
Junying Xu
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TLR2 Promotes Glioma Immune Evasion by Downregulating MHC Class II Molecules in MicrogliaQ91068371
GBP5 promotes NLRP3 inflammasome assembly and immunity in mammalsQ24310380
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockadeQ24535835
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CTLA-4 ligation blocks CD28-dependent T cell activationQ24678229
SOCS3 binds specific receptor–JAK complexes to control cytokine signaling by direct kinase inhibitionQ27676669
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PD-1 and its ligands in tolerance and immunityQ28131650
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survivalQ29547865
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PD-1 blockade induces responses by inhibiting adaptive immune resistanceQ29620856
Glial cells suppress postencephalitic CD8+ T lymphocytes through PD-L1.Q34076317
Blockade of B7-H1 and PD-1 by monoclonal antibodies potentiates cancer therapeutic immunityQ34554995
IFN-γ from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer.Q35677893
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PD-L1 expression and prognostic impact in glioblastomaQ36493843
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Molecular and clinical characterization of PD-L1 expression at transcriptional level via 976 samples of brain gliomaQ37477267
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PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunctionQ39206599
Medullary carcinoma of the colon: a distinct morphology reveals a distinctive immunoregulatory microenvironment.Q39930421
PD-L1 partially protects renal tubular epithelial cells from the attack of CD8+ cytotoxic T cellsQ40163138
CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor CellsQ40619963
T cell-mediated, IFN-gamma-facilitated rejection of murine B16 melanomasQ41024072
PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome.Q41526004
GM-CSF promotes the immunosuppressive activity of glioma-infiltrating myeloid cells through interleukin-4 receptor-α.Q41870476
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PD-L1 expression by neurons nearby tumors indicates better prognosis in glioblastoma patientsQ47679044
First-line pembrolizumab in cisplatin-ineligible patients with locally advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052): a multicentre, single-arm, phase 2 study.Q47717093
Role of immune microenvironment in gastrointestinal stromal tumours.Q47856440
The role of T cells in allografted tumor rejection: IFN-gamma released from T cells is essential for induction of effector macrophages in the rejection siteQ47936664
Cross-talk between TNF-α and IFN-γ signaling in induction of B7-H1 expression in hepatocellular carcinoma cells.Q48091555
Decitibine improve the efficiency of anti-PD-1 therapy via activating the response to IFN/PD-L1 signal of lung cancer cellsQ50107002
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectimmunologyQ101929
P304page(s)290
P577publication date2018-10-17
P1433published inJournal of NeuroinflammationQ15716679
P1476titleThe IFN-γ/PD-L1 axis between T cells and tumor microenvironment: hints for glioma anti-PD-1/PD-L1 therapy
P478volume15

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cites work (P2860)
Q96128311ACT001 reduces the expression of PD-L1 by inhibiting the phosphorylation of STAT3 in glioblastoma
Q64102974Distinct interferon signatures stratify inflammatory and dysimmune myopathies
Q64083844Growth and differentiation factor 15 regulates PD-L1 expression in glioblastoma
Q89907531IFI30 Is a Novel Immune-Related Target with Predicting Value of Prognosis and Treatment Response in Glioblastoma
Q91711786NGS Evaluation of Colorectal Cancer Reveals Interferon Gamma Dependent Expression of Immune Checkpoint Genes and Identification of Novel IFNγ Induced Genes
Q90069145Novel Human Anti-PD-L1 mAbs Inhibit Immune-Independent Tumor Cell Growth and PD-L1 Associated Intracellular Signalling
Q97525213PD-L1 Expression in Glioblastoma, the Clinical and Prognostic Significance: A Systematic Literature Review and Meta-Analysis
Q64290717RelB acts as a molecular switch driving chronic inflammation in glioblastoma multiforme
Q91709281The impact of systemic precision medicine and immunotherapy treatments on brain metastases

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