HIF2A-LOX pathway promotes fibrotic tissue remodeling in thyroid-associated orbitopathy

scientific article published on 01 January 2019

HIF2A-LOX pathway promotes fibrotic tissue remodeling in thyroid-associated orbitopathy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1210/EN.2018-00272
P932PMC publication ID6293089
P698PubMed publication ID30388216

P50authorTae-Hwa ChunQ57321331
Terry J. SmithQ45933677
P2093author name stringStephen Atkins
Alon Kahana
Fumihito Hikage
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A small molecule antagonist inhibits thyrotropin receptor antibody-induced orbital fibroblast functions involved in the pathogenesis of Graves ophthalmopathyQ36817224
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Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction.Q38351966
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A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors.Q39108970
Orbital decompression in Graves' disease. The predictability of reduction of proptosisQ39260297
Inhibitors of oxygen sensing prolyl hydroxylases regulate nuclear localization of the transcription factors Smad2 and YAP/TAZ involved in CTGF synthesisQ39786758
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Hypoxia-inducible factor 1alpha induces fibrosis and insulin resistance in white adipose tissue.Q43071652
Orbital fibroblast heterogeneity may determine the clinical presentation of thyroid-associated ophthalmopathyQ43853007
Cigarette smoking decreases tissue oxygenQ46041487
Pathogenic Phenotype of Adipogenesis and Hyaluronan in Orbital Fibroblasts From Female Graves' Orbitopathy Mouse ModelQ48017800
Decellularized adipose tissue microcarriers as a dynamic culture platform for human adipose-derived stem/stromal cell expansionQ48883501
Hypoxia-Dependent HIF-1 Activation Impacts on Tissue Remodeling in Graves' Ophthalmopathy-Implications for SmokingQ50229189
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)20-35
P577publication date2019-01-01
P1433published inEndocrinologyQ3054009
P1476titleHIF2A-LOX Pathway Promotes Fibrotic Tissue Remodeling in Thyroid-Associated Orbitopathy
P478volume160

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cites work (P2860)
Q64092715Cancer-Associated Fibroblasts Build and Secure the Tumor Microenvironment
Q99371195Identification of differentially expressed long non-coding RNAs and mRNAs in orbital adipose/connective tissue of thyroid-associated ophthalmopathy
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Q92155112Possible Contribution of Inflammation-Associated Hypoxia to Increased K2P5.1 K+ Channel Expression in CD4+ T cells of the Mouse Model for Inflammatory Bowel Disease
Q94686849Prostaglandin F2α agonist-induced suppression of 3T3-L1 cell adipogenesis affects spatial formation of extra-cellular matrix
Q102220295ROCK inhibitors beneficially alter the spatial configuration of TGFβ2-treated 3D organoids from a human trabecular meshwork (HTM)
Q89843708Thyroid-associated ophthalmopathy: Emergence of teprotumumab as a promising medical therapy

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