Histone acetyl transferase TIP60 inhibits the replication of influenza a virus by activation the TBK1-IRF3 pathway

scientific article published on 08 November 2018

Histone acetyl transferase TIP60 inhibits the replication of influenza a virus by activation the TBK1-IRF3 pathway is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1186/S12985-018-1079-3
P932PMC publication ID6225679
P698PubMed publication ID30409205

P50authorHongxuan HeQ92798712
P2093author name stringBo Wang
Meng Li
Lin Chen
Jing Luo
Juan Du
Chengmin Wang
Chengmei Huang
Guoyao Ma
Jiajun Ma
Yungfu Chang
P2860cites workInfluenza A viral nucleoprotein interacts with cytoskeleton scaffolding protein α-actinin-4 for viral replicationQ24297090
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Identification of a novel splice variant form of the influenza A virus M2 ion channel with an antigenically distinct ectodomainQ27341132
A novel influenza A virus mitochondrial protein that induces cell death.Q27863709
RNA polymerase of influenza virus: role of NP in RNA chain elongationQ27865281
Tip60 is a co-repressor for STAT3Q28205252
Cellular functions of TIP60Q28240003
A human T-cell lymphotropic virus type 1 enhancer of Myc transforming potential stabilizes Myc-TIP60 transcriptional interactionsQ28259102
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATMQ28270543
Identification of a cellular protein that specifically interacts with the essential cysteine region of the HIV-1 Tat transactivatorQ28276496
The c-MYC oncoprotein is a substrate of the acetyltransferases hGCN5/PCAF and TIP60Q28295870
Tip60 degradation by adenovirus relieves transcriptional repression of viral transcriptional activator EIA.Q30413802
Tip60 regulates MT1-MMP transcription and invasion of glioblastoma cells through NF-κB pathway.Q52147965
Deubiquitination of Tip60 by USP7 determines the activity of the p53-dependent apoptotic pathwayQ30415089
Destabilization of TIP60 by human papillomavirus E6 results in attenuation of TIP60-dependent transcriptional regulation and apoptotic pathwayQ30431944
Nuclear factor 90 negatively regulates influenza virus replication by interacting with viral nucleoproteinQ33459671
Identification of influenza A nucleoprotein as an antiviral targetQ33590644
Global impact of influenza virus on cellular pathways is mediated by both replication-dependent and -independent eventsQ33839711
The influenza virus nucleoprotein: a multifunctional RNA-binding protein pivotal to virus replication.Q34119838
Identification of a novel multiple kinase inhibitor with potent antiviral activity against influenza virus by reducing viral polymerase activityQ35173488
The diverse superfamily of lysine acetyltransferases and their roles in leukemia and other diseasesQ35666251
A small-RNA enhancer of viral polymerase activityQ36414388
Human Heat shock protein 40 (Hsp40/DnaJB1) promotes influenza A virus replication by assisting nuclear import of viral ribonucleoproteinsQ36448856
An overlapping protein-coding region in influenza A virus segment 3 modulates the host responseQ36554219
Identification of novel influenza A virus proteins translated from PA mRNAQ36607099
Host Protein Moloney Leukemia Virus 10 (MOV10) Acts as a Restriction Factor of Influenza A Virus by Inhibiting the Nuclear Import of the Viral NucleoproteinQ36736357
Influenza A virus nucleoprotein induces apoptosis in human airway epithelial cells: implications of a novel interaction between nucleoprotein and host protein ClusterinQ36738106
Adaptive mutation in influenza A virus non-structural gene is linked to host switching and induces a novel protein by alternative splicingQ36779746
PDCD5 interacts with Tip60 and functions as a cooperator in acetyltransferase activity and DNA damage-induced apoptosisQ37133925
A complicated message: Identification of a novel PB1-related protein translated from influenza A virus segment 2 mRNA.Q37275127
Interplay between influenza A virus and the innate immune signalingQ37603801
Influenza A Virus Dysregulates Host Histone Deacetylase 1 That Inhibits Viral Infection in Lung Epithelial CellsQ38791236
The BM2 protein of influenza B virus interacts with p53 and inhibits its transcriptional and apoptotic activitiesQ38910943
ING5 is a Tip60 cofactor that acetylates p53 in response to DNA damageQ39168173
Antiviral inhibition targeting the HCMV kinase pUL97 requires pUL27-dependent degradation of Tip60 acetyltransferase and cell-cycle arrestQ39592337
Amino Acid Substitution K470R in the Nucleoprotein Increases the Virulence of H5N1 Influenza A Virus in MammalsQ40108458
Role of the histone acetyl transferase Tip60 in the p53 pathwayQ40525578
Characterization and expression of the mouse tat interactive protein 60 kD (TIP60) geneQ40728800
Antiviral activity of SA-2 against influenza A virus in vitro/vivo and its inhibition of RNA polymeraseQ40820859
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosisQ45345472
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageQuantQ112270642
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectinfluenza A virusQ834390
P304page(s)172
P577publication date2018-11-08
P1433published inVirology JournalQ7934868
P1476titleHistone acetyl transferase TIP60 inhibits the replication of influenza a virus by activation the TBK1-IRF3 pathway
P478volume15

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Q92553830Epigenetic factor siRNA screen during primary KSHV infection identifies novel host restriction factors for the lytic cycle of KSHVcites workP2860

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