MERS coronavirus outbreak: Implications for emerging viral infections

scientific article published on 18 October 2018

MERS coronavirus outbreak: Implications for emerging viral infections is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/J.DIAGMICROBIO.2018.10.011
P932PMC publication ID7127703
P698PubMed publication ID30413355

P50authorZiad A MemishQ76089502
Ali A RabaanQ87010484
Jaffar A. Al-TawfiqQ40672517
P2093author name stringAwad Al-Omari
Samer Salih
P2860cites workSARS: systematic review of treatment effectsQ21144696
Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMCQ24329089
Middle East respiratory syndrome coronavirus in bats, Saudi ArabiaQ24596439
Human coronavirus EMC does not require the SARS-coronavirus receptor and maintains broad replicative capability in mammalian cell linesQ24600523
Middle East respiratory syndrome coronavirus (MERS-CoV): announcement of the Coronavirus Study GroupQ24604486
Middle East respiratory syndrome coronavirus: transmission, virology and therapeutic targeting to aid in outbreak controlQ26796501
Receptor-binding domain-based subunit vaccines against MERS-CoVQ26851979
The effectiveness of convalescent plasma and hyperimmune immunoglobulin for the treatment of severe acute respiratory infections of viral etiology: a systematic review and exploratory meta-analysisQ27001157
Current advancements and potential strategies in the development of MERS-CoV vaccinesQ27012578
Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4Q27678981
Structure-based discovery of Middle East respiratory syndrome coronavirus fusion inhibitorQ27689029
Bat origins of MERS-CoV supported by bat coronavirus HKU4 usage of human receptor CD26Q27695604
Coronavirus as a possible cause of severe acute respiratory syndromeQ28200848
Characterization of a novel coronavirus associated with severe acute respiratory syndromeQ28202401
Identification of a new human coronavirusQ29615906
Isolation of a novel coronavirus from a man with pneumonia in Saudi ArabiaQ29618053
The Genome sequence of the SARS-associated coronavirusQ29619007
Middle East Respiratory Syndrome Coronavirus Outbreak in the Republic of Korea, 2015.Q30202400
Serological assays for emerging coronaviruses: challenges and pitfallsQ30210679
The role of laboratory diagnostics in emerging viral infections: the example of the Middle East respiratory syndrome epidemicQ30235533
Prevalence of comorbidities in the Middle East respiratory syndrome coronavirus (MERS-CoV): a systematic review and meta-analysisQ30249264
Dromedary Camels and the Transmission of Middle East Respiratory Syndrome Coronavirus (MERS-CoV).Q30252107
Feasibility, safety, clinical, and laboratory effects of convalescent plasma therapy for patients with Middle East respiratory syndrome coronavirus infection: a study protocolQ30277992
Distribution and absence of generalized lesions in mice following single dose intramuscular inoculation of the vaccine candidate MVA-MERS-SQ56564203
Ultrapotent Human Neutralizing Antibody Repertoires Against Middle East Respiratory Syndrome Coronavirus From a Recovered PatientQ64137589
Do pulmonary radiographic findings at presentation predict mortality in patients with community-acquired pneumonia?Q71714527
Update: Recommendations for Middle East respiratory syndrome coronavirus (MERS-CoV).Q42255644
First cases of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections in France, investigations and implications for the prevention of human-to-human transmission, France, May 2013.Q42258061
MERS-CoV Infection of Alpaca in a Region Where MERS-CoV is EndemicQ42762388
Close relative of human Middle East respiratory syndrome coronavirus in bat, South AfricaQ42931174
Objective Determination of End of MERS Outbreak, South Korea, 2015.Q43110283
Emerging human middle East respiratory syndrome coronavirus causes widespread infection and alveolar damage in human lungsQ43507223
Human intestinal tract serves as an alternative infection route for Middle East respiratory syndrome coronavirus.Q43628487
Corticosteroid Therapy for Critically Ill Patients with the Middle East Respiratory SyndromeQ45073537
Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitorsQ45659807
Middle East respiratory syndrome coronavirus infections in health care workersQ45723498
A new virus isolated from the human respiratory tractQ45825116
Risk factors for severity and mortality in patients with MERS-CoV: Analysis of publicly available data from Saudi Arabia.Q45906708
Preventing healthcare-associated transmission of the Middle East Respiratory Syndrome (MERS): Our Achilles heel.Q46551580
Middle East Respiratory Syndrome Coronavirus Nonstructural Protein 16 Is Necessary for Interferon Resistance and Viral PathogenesisQ47107616
Estimating survival rates in MERS-CoV patients 14 and 45 days after experiencing symptoms and determining the differences in survival rates by demographic data, disease characteristics and regions: a worldwide study.Q47260596
A recombinant VSV-vectored MERS-CoV vaccine induces neutralizing antibody and T cell responses in rhesus monkeys after single dose immunizationQ47288304
MERS-CoV 4b protein interferes with the NF-κB-dependent innate immune response during infection.Q47548908
MERS-CoV and H5N1 influenza virus antagonize antigen presentation by altering the epigenetic landscapeQ47552814
Development of Middle East Respiratory Syndrome Coronavirus vaccines - advances and challengesQ47607374
Histopathology of Middle East respiratory syndrome coronovirus (MERS-CoV) infection - clinicopathological and ultrastructural study.Q47657940
DPP4, the Middle East Respiratory Syndrome Coronavirus Receptor, is Upregulated in Lungs of Smokers and Chronic Obstructive Pulmonary Disease PatientsQ47666922
Evaluation of a Real-Time Reverse Transcription-PCR (RT-PCR) Assay for Detection of Middle East Respiratory Syndrome Coronavirus (MERS-CoV) in Clinical Samples from an Outbreak in South Korea in 2015.Q47875863
Severe acute respiratory syndrome: radiographic appearances and pattern of progression in 138 patients.Q51672487
Engineering a stable CHO cell line for the expression of a MERS-coronavirus vaccine antigen.Q51730564
MERS transmission and risk factors: a systematic review.Q53069767
Effect of interferon alpha and cyclosporine treatment separately and in combination on Middle East Respiratory Syndrome Coronavirus (MERS-CoV) replication in a human in-vitro and ex-vivo culture model.Q54208634
Heterologous prime-boost vaccination with adenoviral vector and protein nanoparticles induces both Th1 and Th2 responses against Middle East respiratory syndrome coronavirus.Q54217812
Middle East respiratory syndrome coronavirus: risk factors and determinants of primary, household, and nosocomial transmission.Q54230978
Unusual presentation of Middle East respiratory syndrome coronavirus leading to a large outbreak in Riyadh during 2017.Q54234800
MERS-CoV pathogenesis and antiviral efficacy of licensed drugs in human monocyte-derived antigen-presenting cells.Q54250885
Comparative epidemiology of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia and South Korea.Q38739674
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 Is an Important Surface Attachment Factor That Facilitates Entry of Middle East Respiratory Syndrome CoronavirusQ38753926
Coronavirus Host Range Expansion and Middle East Respiratory Syndrome Coronavirus Emergence: Biochemical Mechanisms and Evolutionary PerspectivesQ38766689
Rapid generation of a human monoclonal antibody to combat Middle East respiratory syndromeQ38776321
Middle East Respiratory Syndrome Coronavirus: What Does a Radiologist Need to Know?Q38783084
MERS-CoV diagnosis: An update.Q38815393
Patient characteristics infected with Middle East respiratory syndrome coronavirus infection in a tertiary hospitalQ38868439
Human cell tropism and innate immune system interactions of human respiratory coronavirus EMC compared to those of severe acute respiratory syndrome coronavirusQ39187107
Seroepidemiology for MERS coronavirus using microneutralisation and pseudoparticle virus neutralisation assays reveal a high prevalence of antibody in dromedary camels in Egypt, June 2013.Q39349816
Single-dose treatment with a humanized neutralizing antibody affords full protection of a human transgenic mouse model from lethal Middle East respiratory syndrome (MERS)-coronavirus infectionQ39677274
High secretion of interferons by human plasmacytoid dendritic cells upon recognition of Middle East respiratory syndrome coronavirusQ39794655
Human infection with MERS coronavirus after exposure to infected camels, Saudi Arabia, 2013.Q40009251
Identification of a Novel Inhibitor against Middle East Respiratory Syndrome CoronavirusQ40041480
Inclusion of MERS-spike protein ELISA in algorithm to determine serologic evidence of MERS-CoV infectionQ40041686
Structural insights into the Middle East respiratory syndrome coronavirus 4a protein and its dsRNA binding mechanismQ40044568
A Novel Dynamic Model Describing the Spread of the MERS-CoV and the Expression of Dipeptidyl Peptidase 4.Q40052186
Assessing the Detection of Middle East Respiratory Syndrome Coronavirus IgG in Suspected and Proven Cases of Middle East Respiratory Syndrome Coronavirus InfectionQ40057508
A review of candidate therapies for Middle East respiratory syndrome from a molecular perspective.Q40064548
Recovery from the Middle East respiratory syndrome is associated with antibody and T-cell responses.Q40094147
Clinical Implications of 5 Cases of Middle East Respiratory Syndrome Coronavirus Infection in a South Korean OutbreakQ40123706
Longitudinal study of Middle East Respiratory Syndrome coronavirus infection in dromedary camel herds in Saudi Arabia, 2014-2015.Q40152026
IFN-α2a or IFN-β1a in combination with ribavirin to treat Middle East respiratory syndrome coronavirus pneumonia: a retrospective studyQ40159258
ChAdOx1 and MVA based vaccine candidates against MERS-CoV elicit neutralising antibodies and cellular immune responses in miceQ40173497
Clinical aspects and outcomes of 70 patients with Middle East respiratory syndrome coronavirus infection: a single-center experience in Saudi ArabiaQ40187493
Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi ArabiaQ40200316
Middle East respiratory syndrome coronavirus disease in childrenQ40209279
Structural Insights into the Interaction of Coronavirus Papain-Like Proteases and Interferon-Stimulated Gene Product 15 from Different Species.Q40229759
Efficacy of antibody-based therapies against Middle East respiratory syndrome coronavirus (MERS-CoV) in common marmosets.Q40252744
Differential Expression of the Middle East Respiratory Syndrome Coronavirus Receptor in the Upper Respiratory Tracts of Humans and Dromedary CamelsQ40336588
Middle east respiratory syndrome corona virus spike glycoprotein suppresses macrophage responses via DPP4-mediated induction of IRAK-M and PPARγ.Q40359845
Middle East Respiratory Syndrome Coronavirus Infection During Pregnancy: A Report of 5 Cases From Saudi ArabiaQ40631027
Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C BetacoronavirusesQ36694030
Middle East Respiratory Syndrome Coronavirus NS4b Protein Inhibits Host RNase L Activation.Q36755302
Prophylaxis With a Middle East Respiratory Syndrome Coronavirus (MERS-CoV)-Specific Human Monoclonal Antibody Protects Rabbits From MERS-CoV InfectionQ36816625
Evolutionary Dynamics of MERS-CoV: Potential Recombination, Positive Selection and TransmissionQ36865015
Presentation and outcome of Middle East respiratory syndrome in Saudi intensive care unit patientsQ36879745
Glycopeptide Antibiotics Potently Inhibit Cathepsin L in the Late Endosome/Lysosome and Block the Entry of Ebola Virus, Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV).Q36884852
Outbreak of Middle East Respiratory Syndrome at Tertiary Care Hospital, Jeddah, Saudi Arabia, 2014Q36884958
The structural and accessory proteins M, ORF 4a, ORF 4b, and ORF 5 of Middle East respiratory syndrome coronavirus (MERS-CoV) are potent interferon antagonistsQ36922964
MERS-CoV Antibodies in Humans, Africa, 2013-2014.Q36935271
Analytical and Clinical Validation of Six Commercial Middle East Respiratory Syndrome Coronavirus RNA Detection Kits Based on Real-Time Reverse-Transcription PCR.Q37084139
Morphogenesis of Avian Infectious Bronchitis Virus and a Related Human Virus (Strain 229E)Q37122632
Passive Transfer of A Germline-like Neutralizing Human Monoclonal Antibody Protects Transgenic Mice Against Lethal Middle East Respiratory Syndrome Coronavirus InfectionQ37188934
Middle East respiratory syndrome coronavirus infection mediated by the transmembrane serine protease TMPRSS2.Q37336487
Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay.Q37358618
Middle East respiratory syndrome coronavirus disease is rare in children: An update from Saudi ArabiaQ37399674
CD8+ T Cells and Macrophages Regulate Pathogenesis in a Mouse Model of Middle East Respiratory SyndromeQ37512816
Recombinant Receptor-Binding Domains of Multiple Middle East Respiratory Syndrome Coronaviruses (MERS-CoVs) Induce Cross-Neutralizing Antibodies against Divergent Human and Camel MERS-CoVs and Antibody Escape MutantsQ37512915
Real-time reverse transcription-PCR assay panel for Middle East respiratory syndrome coronavirusQ37546593
X-ray Structure and Enzymatic Activity Profile of a Core Papain-like Protease of MERS Coronavirus with utility for structure-based drug designQ37581697
Spread, circulation, and evolution of the Middle East respiratory syndrome coronavirusQ37621643
A previously undescribed coronavirus associated with respiratory disease in humansQ37647570
Antibodies against MERS coronavirus in dromedary camels, United Arab Emirates, 2003 and 2013.Q37664563
Cross-sectional surveillance of Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels and other mammals in Egypt, August 2015 to January 2016Q37708530
Middle east respiratory syndrome coronavirus 4a protein is a double-stranded RNA-binding protein that suppresses PACT-induced activation of RIG-I and MDA5 in the innate antiviral response.Q37713995
Serologic Evidence for MERS-CoV Infection in Dromedary Camels, Punjab, Pakistan, 2012-2015Q37739645
Biogenesis and dynamics of the coronavirus replicative structuresQ38064286
Sensitivity of SARS/MERS CoV to interferons and other drugs based on achievable serum concentrations in humansQ38229070
Human-Dromedary Camel Interactions and the Risk of Acquiring Zoonotic Middle East Respiratory Syndrome Coronavirus Infection.Q38302221
MERS and the dromedary camel trade between Africa and the Middle EastQ38379691
Middle East respiratory syndrome coronavirus in childrenQ38398169
Bat-to-human: spike features determining 'host jump' of coronaviruses SARS-CoV, MERS-CoV, and beyondQ38553361
The ORF4b-encoded accessory proteins of Middle East respiratory syndrome coronavirus and two related bat coronaviruses localize to the nucleus and inhibit innate immune signallingQ38595331
MERS-CoV Accessory ORFs Play Key Role for Infection and PathogenesisQ38638572
The Evolution of Antiviral Defense SystemsQ38729624
Dipeptidyl Peptidase 4 Distribution in the Human Respiratory Tract: Implications for the Middle East Respiratory SyndromeQ36468760
Lessons learned from new emerging infectious disease, Middle East Respiratory Syndrome coronavirus outbreak in KoreaQ36488813
Treatment strategies for Middle East respiratory syndrome coronavirusQ36555622
Middle East Respiratory Syndrome Coronavirus during Pregnancy, Abu Dhabi, United Arab Emirates, 2013.Q36617031
Identifying determinants of heterogeneous transmission dynamics of the Middle East respiratory syndrome (MERS) outbreak in the Republic of Korea, 2015: a retrospective epidemiological analysisQ36625323
3B11-N, a monoclonal antibody against MERS-CoV, reduces lung pathology in rhesus monkeys following intratracheal inoculation of MERS-CoV Jordan-n3/2012Q36626864
Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk.Q30351904
Ecology, evolution and classification of bat coronaviruses in the aftermath of SARS.Q30355171
Adjunctive therapies and immunomodulating agents for severe influenza.Q30355446
Atlas of coronavirus replicase structure.Q30357066
Intranasal vaccination with recombinant receptor-binding domain of MERS-CoV spike protein induces much stronger local mucosal immune responses than subcutaneous immunization: Implication for designing novel mucosal MERS vaccines.Q30359335
Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies.Q30362113
Identification of an ideal adjuvant for receptor-binding domain-based subunit vaccines against Middle East respiratory syndrome coronavirus.Q30371303
A Highly Immunogenic and Protective Middle East Respiratory Syndrome Coronavirus Vaccine Based on a Recombinant Measles Virus Vaccine Platform.Q30378994
A humanized neutralizing antibody against MERS-CoV targeting the receptor-binding domain of the spike protein.Q30379384
Hyperimmune IV immunoglobulin treatment: a multicenter double-blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection.Q30427729
Inhibition of novel β coronavirus replication by a combination of interferon-α2b and ribavirinQ30429521
Middle East respiratory syndrome coronavirus in Al-Madinah City, Saudi Arabia: Demographic, clinical and survival dataQ31108162
Epidemiological, demographic, and clinical characteristics of 47 cases of Middle East respiratory syndrome coronavirus disease from Saudi Arabia: a descriptive studyQ33409373
Clinical course and outcomes of critically ill patients with Middle East respiratory syndrome coronavirus infectionQ33413007
Clinical Presentation and Outcomes of Middle East Respiratory Syndrome in the Republic of KoreaQ33434003
Hospital outbreak of Middle East respiratory syndrome coronavirusQ33642332
A conformation-dependent neutralizing monoclonal antibody specifically targeting receptor-binding domain in Middle East respiratory syndrome coronavirus spike protein.Q33743790
MERS coronavirus in dromedary camel herd, Saudi ArabiaQ33816384
Treatment with interferon-α2b and ribavirin improves outcome in MERS-CoV-infected rhesus macaquesQ33887877
Geographic distribution of MERS coronavirus among dromedary camels, AfricaQ33950974
Screening of an FDA-approved compound library identifies four small-molecule inhibitors of Middle East respiratory syndrome coronavirus replication in cell cultureQ34058365
Host species restriction of Middle East respiratory syndrome coronavirus through its receptor, dipeptidyl peptidase 4.Q34059153
Rooting the phylogenetic tree of middle East respiratory syndrome coronavirus by characterization of a conspecific virus from an African batQ34261861
Detection of a novel human coronavirus by real-time reverse-transcription polymerase chain reactionQ34304123
Severe respiratory illness caused by a novel coronavirus, in a patient transferred to the United Kingdom from the Middle East, September 2012.Q34306978
Assays for laboratory confirmation of novel human coronavirus (hCoV-EMC) infections.Q34317027
Family cluster of Middle East respiratory syndrome coronavirus infectionsQ34347450
Clinical features and viral diagnosis of two cases of infection with Middle East Respiratory Syndrome coronavirus: a report of nosocomial transmissionQ34347979
Severe acute respiratory syndrome coronavirus (SARS-CoV) infection inhibition using spike protein heptad repeat-derived peptides.Q34376025
Interferon-stimulated genes: a complex web of host defensesQ34405609
Host cell entry of Middle East respiratory syndrome coronavirus after two-step, furin-mediated activation of the spike proteinQ34408840
Virological and serological analysis of a recent Middle East respiratory syndrome coronavirus infection case on a triple combination antiviral regimenQ34442119
Thiopurine analogs and mycophenolic acid synergistically inhibit the papain-like protease of Middle East respiratory syndrome coronavirusQ34455805
Protease inhibitors targeting coronavirus and filovirus entryQ34461982
Purified coronavirus spike protein nanoparticles induce coronavirus neutralizing antibodies in miceQ40744757
Infection control and prevention practices implemented to reduce transmission risk of Middle East respiratory syndrome-coronavirus in a tertiary care institution in Saudi Arabia.Q40774751
Bioinformatics analysis on molecular mechanism of ribavirin and interferon-α in treating MERS-CoVQ40776786
Epidemiological investigation of MERS-CoV spread in a single hospital in South Korea, May to June 2015.Q40777987
Notes from the Field: Nosocomial Outbreak of Middle East Respiratory Syndrome in a Large Tertiary Care Hospital--Riyadh, Saudi Arabia, 2015.Q40786131
Acute Middle East Respiratory Syndrome Coronavirus: Temporal Lung Changes Observed on the Chest Radiographs of 55 PatientsQ40808656
Middle East respiratory syndrome coronavirus (MERS-CoV) in dromedary camels in Nigeria, 2015.Q40868265
Viral Shedding and Antibody Response in 37 Patients With Middle East Respiratory Syndrome Coronavirus InfectionQ40911125
Presence of antibodies but no evidence for circulation of MERS-CoV in dromedaries on the Canary Islands, 2015.Q40923127
Combination therapy with lopinavir/ritonavir, ribavirin and interferon-α for Middle East respiratory syndromeQ40940972
Presence of Middle East respiratory syndrome coronavirus antibodies in Saudi Arabia: a nationwide, cross-sectional, serological studyQ41088356
Middle East Respiratory Syndrome Coronavirus Efficiently Infects Human Primary T Lymphocytes and Activates the Extrinsic and Intrinsic Apoptosis PathwaysQ41094209
Treatment With Lopinavir/Ritonavir or Interferon-β1b Improves Outcome of MERS-CoV Infection in a Nonhuman Primate Model of Common MarmosetQ41096904
Protective Efficacy of Recombinant Modified Vaccinia Virus Ankara Delivering Middle East Respiratory Syndrome Coronavirus Spike GlycoproteinQ41199088
Systemic and mucosal immunity in mice elicited by a single immunization with human adenovirus type 5 or 41 vector-based vaccines carrying the spike protein of Middle East respiratory syndrome coronavirusQ41242033
2014 MERS-CoV outbreak in Jeddah--a link to health care facilitiesQ41351922
Middle Eastern Respiratory Syndrome Corona Virus (MERS CoV): case reports from a tertiary care hospital in Saudi ArabiaQ41366475
Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study.Q41718118
Characterization of a novel betacoronavirus related to middle East respiratory syndrome coronavirus in European hedgehogsQ41909110
Inhibition of Middle East respiratory syndrome coronavirus infection by anti-CD26 monoclonal antibodyQ41920484
Characterization of novel monoclonal antibodies against the MERS-coronavirus spike protein and their application in species-independent antibody detection by competitive ELISA.Q41921387
Identification of sialic acid-binding function for the Middle East respiratory syndrome coronavirus spike glycoprotein.Q41935096
Evidence for camel-to-human transmission of MERS coronavirusQ42212312
Respiratory tract samples, viral load, and genome fraction yield in patients with Middle East respiratory syndromeQ42214884
Ribavirin and interferon-α2b as primary and preventive treatment for Middle East respiratory syndrome coronavirus: a preliminary report of two casesQ42218522
Performance and clinical validation of the RealStar MERS-CoV Kit for detection of Middle East respiratory syndrome coronavirus RNA.Q42224974
Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigationQ42236132
Screening for Middle East respiratory syndrome coronavirus infection in hospital patients and their healthcare worker and family contacts: a prospective descriptive studyQ42241378
Ribavirin and interferon therapy in patients infected with the Middle East respiratory syndrome coronavirus: an observational studyQ42244203
Active replication of Middle East respiratory syndrome coronavirus and aberrant induction of inflammatory cytokines and chemokines in human macrophages: implications for pathogenesisQ42246665
Middle East Respiratory Syndrome (MERS) coronavirus seroprevalence in domestic livestock in Saudi Arabia, 2010 to 2013.Q42248788
Middle East Respiratory Syndrome coronavirus (MERS-CoV) serology in major livestock species in an affected region in Jordan, June to September 2013.Q42248792
Middle East respiratory syndrome coronavirus neutralising serum antibodies in dromedary camels: a comparative serological study.Q42251659
Novel coronavirus infections in Jordan, April 2012: epidemiological findings from a retrospective investigationQ42253657
Middle East respiratory syndrome coronavirus: another zoonotic betacoronavirus causing SARS-like diseaseQ34468689
MERS coronavirus: diagnostics, epidemiology and transmissionQ34506268
Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirusQ34593578
MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-α treatmentQ34650943
Clinical features and virological analysis of a case of Middle East respiratory syndrome coronavirus infectionQ34653376
Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment.Q34656339
An observational, laboratory-based study of outbreaks of middle East respiratory syndrome coronavirus in Jeddah and Riyadh, kingdom of Saudi Arabia, 2014.Q35003400
Role of the spike glycoprotein of human Middle East respiratory syndrome coronavirus (MERS-CoV) in virus entry and syncytia formationQ35009468
A truncated receptor-binding domain of MERS-CoV spike protein potently inhibits MERS-CoV infection and induces strong neutralizing antibody responses: implication for developing therapeutics and vaccinesQ35063993
The multifunctional or moonlighting protein CD26/DPPIV.Q35089114
Potent neutralization of MERS-CoV by human neutralizing monoclonal antibodies to the viral spike glycoproteinQ35159147
Development and validation of a rapid immunochromatographic assay for detection of Middle East respiratory syndrome coronavirus antigen in dromedary camelsQ35193329
Real-time sequence-validated loop-mediated isothermal amplification assays for detection of Middle East respiratory syndrome coronavirus (MERS-CoV).Q35347932
High proportion of MERS-CoV shedding dromedaries at slaughterhouse with a potential epidemiological link to human cases, Qatar 2014Q35860307
Development and Evaluation of Novel Real-Time Reverse Transcription-PCR Assays with Locked Nucleic Acid Probes Targeting Leader Sequences of Human-Pathogenic CoronavirusesQ35868692
Multi-Organ Damage in Human Dipeptidyl Peptidase 4 Transgenic Mice Infected with Middle East Respiratory Syndrome-CoronavirusQ35877765
Two Mutations Were Critical for Bat-to-Human Transmission of Middle East Respiratory Syndrome CoronavirusQ35913859
Structural basis for the neutralization of MERS-CoV by a human monoclonal antibody MERS-27Q35964208
A synthetic consensus anti-spike protein DNA vaccine induces protective immunity against Middle East respiratory syndrome coronavirus in nonhuman primatesQ36069589
A sensitive and specific antigen detection assay for Middle East respiratory syndrome coronavirusQ36073689
Middle East Respiratory Coronavirus Accessory Protein 4a Inhibits PKR-Mediated Antiviral Stress ResponsesQ36175026
Stillbirth during infection with Middle East respiratory syndrome coronavirusQ36201318
Clinical determinants of the severity of Middle East respiratory syndrome (MERS): a systematic review and meta-analysisQ36207135
Molecular Epidemiology of Hospital Outbreak of Middle East Respiratory Syndrome, Riyadh, Saudi Arabia, 2014.Q36212147
Middle East Respiratory Syndrome Coronavirus Superspreading Event Involving 81 Persons, Korea 2015.Q36241778
Early endonuclease-mediated evasion of RNA sensing ensures efficient coronavirus replicationQ36269957
Clinical and laboratory findings of the first imported case of Middle East respiratory syndrome coronavirus to the United StatesQ36293993
Protective Effect of Intranasal Regimens Containing Peptidic Middle East Respiratory Syndrome Coronavirus Fusion Inhibitor Against MERS-CoV InfectionQ36306931
Middle East respiratory syndrome coronavirus ORF4b protein inhibits type I interferon production through both cytoplasmic and nuclear targetsQ36343316
Middle East respiratory syndrome coronavirus infection: virus-host cell interactions and implications on pathogenesisQ36393296
Renal Complications and Their Prognosis in Korean Patients with Middle East Respiratory Syndrome-Coronavirus from the Central MERS-CoV Designated HospitalQ36400547
Risk Factors for Primary Middle East Respiratory Syndrome Coronavirus Illness in Humans, Saudi Arabia, 2014.Q36418201
Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and DiseaseQ36433987
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectCoronaviridaeQ1134583
P304page(s)265-285
P577publication date2018-10-18
2019-03-01
P1433published inDiagnostic Microbiology and Infectious DiseaseQ15763479
P1476titleMERS coronavirus outbreak: Implications for emerging viral infections
P478volume93

Reverse relations

cites work (P2860)
Q64111229Bat Research Networks and Viral Surveillance: Gaps and Opportunities in Western Asia
Q64119316Bioaerosols and Transmission, a Diverse and Growing Community of Practice
Q97528635Drug targets for COVID-19 therapeutics: Ongoing global efforts
Q108832741Effect of ORF7 of SARS-CoV-2 on the Chemotaxis of Monocytes and Neutrophils In Vitro
Q97521731Flattening the COVID-19 Curve With Natural Killer Cell Based Immunotherapies
Q102141614High-content screening of Thai medicinal plants reveals Boesenbergia rotunda extract and its component Panduratin A as anti-SARS-CoV-2 agents
Q84316149Human Coronaviruses and Other Respiratory Viruses: Underestimated Opportunistic Pathogens of the Central Nervous System?
Q97527042Importance of the One Health approach to study the SARS-CoV-2 in Latin America
Q91579137Microneedle array delivered recombinant coronavirus vaccines: Immunogenicity and rapid translational development
Q64359214New and emerging infectious diseases (Ebola, Middle Eastern respiratory syndrome coronavirus, carbapenem-resistant Enterobacteriaceae, Candida auris): Focus on environmental survival and germicide susceptibility
Q92102886Recent apprise on coronavirus and its terrible insinuations
Q97537589Self-amplifying RNA SARS-CoV-2 lipid nanoparticle vaccine candidate induces high neutralizing antibody titers in mice
Q102378266Structure of nonstructural protein 1 from SARS-CoV-2
Q98613568Susceptibility to SARS, MERS, and COVID-19 from animal health perspective
Q98288123The 2019-2020 Novel Coronavirus (Severe Acute Respiratory Syndrome Coronavirus 2) Pandemic: A Joint American College of Academic International Medicine-World Academic Council of Emergency Medicine Multidisciplinary COVID-19 Working Group Consensus P
Q89840059The SARS, MERS and novel coronavirus (COVID-19) epidemics, the newest and biggest global health threats: what lessons have we learned?
Q92117598The epidemiological and clinical features of COVID-19 and lessons from this global infectious public health event
Q91935487The epidemiology and clinical information about COVID-19
Q98461071Where we missed? Middle East Respiratory Syndrome (MERS-CoV) epidemiology in Saudi Arabia; 2012-2019
Q107982009Why All the Fury over Furin?

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