Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus

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Catalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.01294-14
P932PMC publication ID4248884
P698PubMed publication ID25142582
P5875ResearchGate publication ID264941703

P50authorSusan C. BakerQ19865464
Andrew D. MesecarQ38317666
Xufang DengQ90539286
Anna M. MielechQ114448715
Yahira M Báez-SantosQ114448720
P2860cites workCharacterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumoniaQ24558699
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Thiopurine analogues inhibit papain-like protease of severe acute respiratory syndrome coronavirus.Q44594725
A new virus isolated from the human respiratory tractQ45825116
Papain-like protease 2 (PLP2) from severe acute respiratory syndrome coronavirus (SARS-CoV): expression, purification, characterization, and inhibitionQ46617455
Geranylated flavonoids displaying SARS-CoV papain-like protease inhibition from the fruits of Paulownia tomentosa.Q51036588
No novel coronaviruses identified in a large collection of human nasopharyngeal specimens using family-wide CODEHOP-based primers.Q54288328
Severe acute respiratory syndromeQ56775278
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Phenolic phytochemical displaying SARS-CoV papain-like protease inhibition from the seeds of Psoralea corylifoliaQ85904728
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The ubiquitin codeQ28265104
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Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?Q30223960
Interhuman transmissibility of Middle East respiratory syndrome coronavirus: estimation of pandemic risk.Q30351904
PLP2 of mouse hepatitis virus A59 (MHV-A59) targets TBK1 to negatively regulate cellular type I interferon signaling pathwayQ31001219
A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replicationQ33375590
Structure-based design, synthesis, and biological evaluation of a series of novel and reversible inhibitors for the severe acute respiratory syndrome-coronavirus papain-like proteaseQ33488957
Hospital outbreak of Middle East respiratory syndrome coronavirusQ33642332
Coronaviruses post-SARS: update on replication and pathogenesisQ33694361
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Deubiquitinating and interferon antagonism activities of coronavirus papain-like proteases.Q33826676
Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signalingQ34152661
The RNA helicase Lgp2 inhibits TLR-independent sensing of viral replication by retinoic acid-inducible gene-I.Q34457606
Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzymeQ34595903
Synergistic inhibitor binding to the papain-like protease of human SARS coronavirus: mechanistic and inhibitor design implicationsQ34780031
The emerging complexity of protein ubiquitinationQ35002957
Proteolytic processing, deubiquitinase and interferon antagonist activities of Middle East respiratory syndrome coronavirus papain-like proteaseQ35074220
Distinct immune response in two MERS-CoV-infected patients: can we go from bench to bedside?Q35097505
Ribose 2'-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5.Q35239001
Comparison of SARS and NL63 papain-like protease binding sites and binding site dynamics: inhibitor design implicationsQ36095703
Genomic characterization of a newly discovered coronavirus associated with acute respiratory distress syndrome in humansQ36432023
Recovery in tracheal organ cultures of novel viruses from patients with respiratory diseaseQ36465731
Proteomics analysis unravels the functional repertoire of coronavirus nonstructural protein 3.Q36673320
IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand bindingQ37245607
Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensorsQ37252823
Regulation of IRF-3-dependent innate immunity by the papain-like protease domain of the severe acute respiratory syndrome coronavirusQ37372586
Transmission and evolution of the Middle East respiratory syndrome coronavirus in Saudi Arabia: a descriptive genomic studyQ37504790
Replicative Capacity of MERS Coronavirus in Livestock Cell LinesQ37513472
Identification of severe acute respiratory syndrome coronavirus replicase products and characterization of papain-like protease activityQ37683240
P433issue21
P407language of work or nameEnglishQ1860
P921main subjectmolecular biologyQ7202
CoronaviridaeQ1134583
Middle East respiratory syndrome coronavirusQ4902157
Middle East respiratory syndromeQ16654806
P304page(s)12511-12527
P577publication date2014-08-20
P1433published inJournal of VirologyQ1251128
P1476titleCatalytic function and substrate specificity of the papain-like protease domain of nsp3 from the Middle East respiratory syndrome coronavirus
P478volume88

Reverse relations

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