Jacek Sapa

Polish pharmaceutical scientist

Jacek Sapa is …
instance of (P31):
humanQ5

External links are
P213ISNI0000000111128067
P12541Ludzie Nauki ID (new)hd2HB4YSKeE
P1207NUKAT IDn01043911
P496ORCID iD0000-0003-4670-1665
P7293PLWABN ID9810612496705606
P3124Polish scientist ID101131
P1153Scopus author ID6602911437
P214VIAF ID161420301

P512academic degreehabilitationQ308678
doctorateQ849697
scientific professorship degreeQ55695329
P27country of citizenshipPolandQ36
P184doctoral advisorBarbara FilipekQ59297711
P69educated atJagiellonian UniversityQ189441
P108employerMedical College of Jagiellonian UniversityQ6122616
P734family nameSapaQ21492313
SapaQ21492313
SapaQ21492313
P735given nameJacekQ187837
JacekQ187837
PawełQ19816823
PawełQ19816823
P1412languages spoken, written or signedPolishQ809
P1559name in native languageJacek Sapa
P106occupationresearcherQ1650915
pharmaceutical scientistQ105570105
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q51334897(2-Arylethenyl)-1,3,5-triazin-2-amines as a novel histamine H4 receptor ligands.
Q604736617-3-Chlorophenypiperazinylalkyl derivatives of 8-alkoxy-purine-2,6-dione as a serotonin receptor ligands with potential antidepressant activity
Q28550518A Comparison of the Anorectic Effect and Safety of the Alpha2-Adrenoceptor Ligands Guanfacine and Yohimbine in Rats with Diet-Induced Obesity
Q40594068ANTI-INFLAMMATORY AND ANTIOXIDANT ACTIVITY OF 8-METHOXY-1,3-DIMETHYL-2,6-DIOXO-PURIN-7-YL DERIVATIVES WITH TERMINAL CARBOXYLIC, ESTER OR AMIDE MOIETIES IN ANIMAL MODELS.
Q88032187Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts
Q86476756Analgesic activity of new 8-methoxy-1,3-dimethyl-2,6-dioxo-purin-7-yl derivatives with carboxylic, ester or amide moieties
Q86098508Analgesic and anti-inflammatory activity of 7-substituted purine-2,6-diones
Q95444005Anti-inflammatory activity of lipoic acid in mice peritonitis model
Q48299509Anti-inflammatory, antioxidant, and antiparkinsonian effects of adenosine A2A receptor antagonists.
Q52149069Antiarrhythmic activity in occlusion-reperfusion model of 1-(1H-indol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino} propan-2-ol and its enantiomers.
Q63382961Antiarrhythmic activity of new 2-methoxyphenylpiperazine xanthone derivatives after ischemia/reperfusion in rats
Q42875740Antiarrhythmic activity of novel S-enantiomers of pyrrolidin-2-one derivatives with adrenolytic properties
Q46903664Antiarrhythmic activity of some xanthone derivatives with β1-adrenoceptor affinities in rats.
Q41644207Antiarrhythmic and antioxidant activity of novel pyrrolidin-2-one derivatives with adrenolytic properties.
Q84165362Antiarrhythmic and hypotensive activities of 1-[2-hydroxy-3-(4-phenyl-1-piperazinyl)propyl]-pyrrolidin-2-one (MG-1(R,S)) and its enantiomers
Q51740483Antiarrhythmic and α-Adrenoceptor Antagonistic Properties of Novel Arylpiperazine Derivatives of Pyrrolidin-2-one.
Q63382965Antiarrhythmic, hypotensive and α1-adrenolytic properties of new 2-methoxyphenylpiperazine derivatives of xanthone
Q28550792Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal Models
Q48140118Antidepressant-like activity of a new piperazine derivative of xanthone in the forced swim test in mice: The involvement of serotonergic system.
Q48886230Antidepressant-like activity of the phenylpiperazine pyrrolidin-2-one derivatives in mice.
Q63382975Antidepressant-like properties of (R,S)-HBK-1 and its isomers, new xanthone derivatives, in mice
Q57708302Antiparkinsonian Effects of Novel Adenosine A2A Receptor Antagonists
Q44349321Are anti-inflammatory properties of lipoic acid associated with the formation of hydrogen sulfide?
Q38977969Aryl-1,3,5-triazine derivatives as histamine H4 receptor ligands.
Q51473592Arylsulfonamide derivatives of (aryloxy)ethyl pyrrolidines and piperidines as α1-adrenergic receptor antagonist with uro-selective activity.
Q46526511Biofunctional studies of new 2-methoxyphenylpiperazine xanthone derivatives with α₁-adrenolytic properties
Q104478260Bioresearch of New 1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones
Q112155768Characterization and antidiabetic activity of salicylhydrazone Schiff base vanadium(IV) and (V) complexes
Q42058859Chemically Homogenous Compounds with Antagonistic Properties at All α1-Adrenoceptor Subtypes but not β1-Adrenoceptor Attenuate Adrenaline-Induced Arrhythmia in Rats
Q57476499Correlation of Paraoxonase-1 with the Severity of Crohn's Disease
Q46008778Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity.
Q87772396Design, synthesis, anticonvulsant, and antiarrhythmic properties of novel N-Mannich base and amide derivatives of β-tetralinohydantoin
Q38364945Ergotamine and nicergoline - facts and myths
Q60473668Evaluation of anticonvulsant activity of novel pyrrolidin-2-one derivatives
Q39334754Evaluation of antidepressant-like and anxiolytic-like activity of purinedione-derivatives with affinity for adenosine A2A receptors in mice
Q37273493H3 histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice.
Q58554121HBK-17, a 5-HT Receptor Ligand With Anxiolytic-Like Activity, Preferentially Activates ß-Arrestin Signaling
Q38873393HBK-7 - A new xanthone derivative and a 5-HT1A receptor antagonist with antidepressant-like properties.
Q42089891Hypotensive effect of alpha-lipoic acid after a single administration in rats.
Q46022292In vivo anti-inflammatory activity of lipoic acid derivatives in mice.
Q28213292Investigations on the synthesis and pharmacological properties of N-substituted derivatives of 4-alkoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones
Q96577629KD-64-A new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist-Caffeine does not reduce diet-induced obesity in mice
Q91798309KSK19 - Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice
Q112246857Ligand role on insulin-mimetic properties of vanadium complexes. Structural and biological studies
Q45087318Methylprednisolone- acute spinal cord injury, benefits or risks?
Q41220105Muscle relaxants--the current position in the treatment of spasticity in orthopedics.
Q53099204PRELIMINARY EVALUATION OF CENTRAL NERVOUS SYSTEM ACTIVITY OF (E)-N-2-METHYL-3-PHENYLPROP-2-ENYL ((E)-N- α-METHYLCINNAMYL) DERIVATIVES OF SELECTED AMINOALKANOLS.
Q104691822PSB 603 - a known selective adenosine A2B receptor antagonist - has anti-inflammatory activity in mice
Q96603602Pitolisant protects mice chronically treated with corticosterone from some behavioral but not metabolic changes in corticosterone-induced depression model
Q44183551Preparation of novel derivatives of pyridothiazine-1,1-dioxide and their CNS and antioxidant properties.
Q47324338Pyrrolidin-2-one derivatives may reduce body weight in rats with diet-induced obesity
Q73733814Search for new antiarrhythmic and hypotensive compounds. Synthesis, antiarrhythmic, antihypertensive, and alpha-adrenoceptor blocking activity of novel 1-[(2-hydroxy-3-amino)]-propylpyrrolidin-2-one derivatives
Q63382948Serotonin receptors in depression and anxiety: Insights from animal studies
Q53393422Synthesis and Analgesic Activity of Annelated Xanthine Derivatives in Experimental Models in Rodents.
Q63382966Synthesis and Evaluation of Antidepressant-like Activity of Some 4-Substituted 1-(2-methoxyphenyl)Piperazine Derivatives
Q112135016Synthesis and Evaluation of the Antidepressant-like Properties of HBK-10, a Novel 2-Methoxyphenylpiperazine Derivative Targeting the 5-HT1A and D2 Receptors
Q87243955Synthesis and Pharmacological Activity of a New Series of 1-(1H-Indol-4-yloxy)-3-(2-(2-methoxyphenoxy)ethylamino)propan-2-ol Analogs
Q58691700Synthesis and Pharmacological Evaluation of Novel Silodosin-Based Arylsulfonamide Derivatives as α/α-Adrenergic Receptor Antagonist with Potential Uroselective Profile
Q81277104Synthesis and analgesic action of N-(substituted-ethyl)pyrrole-3,4-dicarboximides
Q112175287Synthesis and antinociceptive activity of four 1 H ‐isoindolo‐1,3(2 H )‐diones
Q52684757Synthesis and biological evaluation of N-arylpiperazine derivatives of 4,4-dimethylisoquinoline-1,3(2H,4H)-dione as potential antiplatelet agents.
Q81255467Synthesis and development of new 2-substituted 1-[3-(4-arylpiperazin-1-yl)propyl]-pyrrolidin-2-one derivatives with antiarrhythmic, hypotensive, and alpha-adrenolytic activity
Q81101075Synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxypropyl]-pyrrolidin-2-one derivatives with anti-arrhythmic, hypotensive, and alpha-adrenolytic activity
Q43202232Synthesis and pharmacological evaluation of new 1-[3-(4-phenylpiperazin-1-yl)-propyl]- and 1-[3-(4-phenylpiperidine)-propyl]- 3-aryl-3-alkyl-pyrrolidin-2-one derivatives with antiarrhythmic and antihypertensive activity
Q43111577Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents
Q46554559Synthesis and pharmacological properties of 1-[2-hydroxy-3-(4-o,m,p-halogenophenyl)- and 3-(4-m-chlorophenyl)-1-piperazinyl]propyl derivatives of amides of 7-methyl-3-phenyl-2,4-dioxo-1,2,3,4-tetrahydropyrido [2,3-d]pyrimidine-5-carboxylic acid with
Q46117349Synthesis and pharmacological properties of new derivatives of 4-alkoxy-6-methyl-1H-pyrrolo[3,4-c]pyridine-1,3(2H)-diones.
Q28213800Synthesis and properties of 4-alkoxy-2-[2-hydroxy-3-(4-o,m,p-halogenoaryl-1 -piperazinyl)propyl]-6-methyl-1H-pyrrolo-[3,4-c]pyridine-1,3(2H)-diones with analgesic and sedative activities
Q45053748Synthesis and properties of N-methyl and N-phenyl derivatives of 1,4-dioxo-1,2,3,4-tetrahydropyrido[3,4-d]pyridazines.
Q44393286Synthesis and properties of tetra(hexa)hydropyrazolo [1,2-a]pyrido[3,4-d]pyridazine derivatives.
Q43921800Synthesis, antiarrhythmic, and antihypertensive effects of novel 1-substituted pyrrolidin-2-one and pyrrolidine derivatives with adrenolytic activity.
Q112155769Synthesis, coordination properties and biological activity of vanadium complexes with hydrazone Schiff base ligands
Q44495095Synthesis, structure and antiarrhythmic properties evaluation of new basic derivatives of 5,5-diphenylhydantoin
Q95512360THE EFFECT OF SEROTONIN 5-HT1A, 5-HT2 RECEPTOR LIGANDS, KETOPROFEN AND THEIR COMBINATION IN MODELS OF INDUCED PAIN IN MICE
Q112135014The Antiarrhythmic Activity of Novel Pyrrolidin-2-one Derivative S-75 in Adrenaline-Induced Arrhythmia
Q64065792The Significance of Lactoperoxidase System in Oral Health: Application and Efficacy in Oral Hygiene Products
Q41931564The antidepressant- and anxiolytic-like activities of new xanthone derivative with piperazine moiety in behavioral tests in mice.
Q48077440The antidepressant-like activity of 6-methoxy-2-[4-(2-methoxyphenyl)piperazin-1-yl]-9H-xanthen-9-one involves serotonergic 5-HT(1A) and 5-HT(2A/C) receptors activation
Q100995819The antidepressant-like activity of chiral xanthone derivatives may be mediated by 5-HT1A receptor and β-arrestin signalling
Q88867837The histamine H3 receptor inverse agonist pitolisant reduces body weight in obese mice
Q60473659The influence of the route of administration of gold nanoparticles on their tissue distribution and basic biochemical parameters: In vivo studies
Q57111935The nitric oxide/soluble cyclic guanylase/cyclic guanosine monophosphate pathway is involved in the cardiovascular effects of a novel α1- and β-adrenoceptor antagonist
Q44723148The possible mechanism of hypotensive activity of some pyrrolidin-2-one derivatives with antagonist properties at alpha1-adrenoceptors
Q38753164The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect.
Q39212534The role of melatonin, neurokinin, neurotrophic tyrosine kinase and glucocorticoid receptors in antidepressant-like effect
Q38753146The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect
Q43534122Tissue distribution of gold nanoparticles after single intravenous administration in mice.
Q112246862Tridentate ONO ligands in vanadium(III-V) complexes - synthesis, characterization and biological activity
Q86999804α-Adrenoceptor antagonistic and hypotensive properties of novel arylpiperazine derivatives of pyrrolidin-2-one

Q59297711Barbara Filipekdoctoral studentP185

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