scholarly article | Q13442814 |
P356 | DOI | 10.1038/NRM3416 |
P698 | PubMed publication ID | 22895435 |
P50 | author | Georg Halder | Q43108514 |
Sirio Dupont | Q50881440 | ||
P2093 | author name string | Stefano Piccolo | |
P2860 | cites work | Yap1 acts downstream of α-catenin to control epidermal proliferation | Q24294904 |
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells | Q24296824 | ||
Inactivation of YAP oncoprotein by the Hippo pathway is involved in cell contact inhibition and tissue growth control | Q24299106 | ||
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and Expanded | Q24299457 | ||
The Hippo pathway regulates Wnt/beta-catenin signaling | Q24307606 | ||
TAZ promotes cell proliferation and epithelial-mesenchymal transition and is inhibited by the hippo pathway | Q24307937 | ||
TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition | Q24310051 | ||
TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal | Q24323998 | ||
TEAD mediates YAP-dependent gene induction and growth control | Q24336045 | ||
Relation of protein synthesis and transglutaminase activity to formation of the cross-linked envelope during terminal differentiation of the cultured human epidermal keratinocyte | Q24339392 | ||
The Hippo Signaling Pathway in Development and Cancer | Q24603986 | ||
Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce epidermal hyperplasia and tumor growth | Q24613142 | ||
α-catenin is a tumor suppressor that controls cell accumulation by regulating the localization and activity of the transcriptional coactivator Yap1 | Q24613385 | ||
Substrate elasticity regulates skeletal muscle stem cell self-renewal in culture | Q24623940 | ||
Matrix crosslinking forces tumor progression by enhancing integrin signaling | Q24646370 | ||
Transcription factor choice in the Hippo signaling pathway: homothorax and yorkie regulation of the microRNA bantam in the progenitor domain of the Drosophila eye imaginal disc | Q24655799 | ||
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases | Q24680631 | ||
Matrix elasticity directs stem cell lineage specification | Q27860761 | ||
Tensional homeostasis and the malignant phenotype | Q27860932 | ||
salvador Promotes both cell cycle exit and apoptosis in Drosophila and is mutated in human cancer cell lines | Q28219379 | ||
Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila | Q28236392 | ||
RETRACTED: Lysyl oxidase is essential for hypoxia-induced metastasis | Q28236828 | ||
Cell shape, cytoskeletal tension, and RhoA regulate stem cell lineage commitment | Q28255124 | ||
The Hippo signaling pathway coordinately regulates cell proliferation and apoptosis by inactivating Yorkie, the Drosophila Homolog of YAP | Q28266862 | ||
SCALLOPED interacts with YORKIE, the nuclear effector of the hippo tumor-suppressor pathway in Drosophila | Q28271058 | ||
The Hippo-YAP pathway in organ size control and tumorigenesis: an updated version | Q28281214 | ||
Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase | Q28301071 | ||
Novel insights into epithelial polarity proteins in Drosophila | Q37870330 | ||
The Hippo pathway and apico-basal cell polarity | Q37875188 | ||
The Hippo pathway in organ size control, tissue regeneration and stem cell self-renewal | Q37909890 | ||
Matrix stiffening sensitizes epithelial cells to EGF and enables the loss of contact inhibition of proliferation | Q39571912 | ||
Combined functional genomic and proteomic approaches identify a PP2A complex as a negative regulator of Hippo signaling | Q39662954 | ||
Hippo pathway-dependent and -independent roles of RASSF6. | Q39792600 | ||
TEADs mediate nuclear retention of TAZ to promote oncogenic transformation | Q39867711 | ||
The TEAD/TEF family of transcription factor Scalloped mediates Hippo signaling in organ size control | Q40015415 | ||
Traction forces exerted through N-cadherin contacts. | Q40246006 | ||
Is the mechanical activity of epithelial cells controlled by deformations or forces? | Q40363795 | ||
Relaxation-expansion model for self-driven retinal morphogenesis: a hypothesis from the perspective of biosystems dynamics at the multi-cellular level | Q40669649 | ||
Mechanisms of mechanical signaling in development and disease | Q41141337 | ||
Cooperative regulation of growth by Yorkie and Mad through bantam | Q41988574 | ||
Mst1 and Mst2 maintain hepatocyte quiescence and suppress hepatocellular carcinoma development through inactivation of the Yap1 oncogene | Q42064207 | ||
Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate. | Q42179070 | ||
The Drosophila RASSF homolog antagonizes the hippo pathway | Q42236170 | ||
Cell-cycle control by physiological matrix elasticity and in vivo tissue stiffening | Q42574965 | ||
Modulating F-actin organization induces organ growth by affecting the Hippo pathway | Q42760112 | ||
Hippo pathway regulation by cell morphology and stress fibers. | Q42806999 | ||
Fibronectin modulation of cell shape and lipogenic gene expression in 3T3-adipocytes | Q42820082 | ||
Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis | Q43998282 | ||
Role of cell shape in growth control | Q44152787 | ||
Hippo promotes proliferation arrest and apoptosis in the Salvador/Warts pathway | Q44591663 | ||
Intercalary regeneration in imaginal wing disk of Drosophila melanogaster | Q45258732 | ||
The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation | Q46192247 | ||
Deletion of beta 1 integrins in mice results in inner cell mass failure and peri-implantation lethality | Q46917727 | ||
The TEAD/TEF family protein Scalloped mediates transcriptional output of the Hippo growth-regulatory pathway | Q47071830 | ||
Shar-pei mediates cell proliferation arrest during imaginal disc growth in Drosophila | Q47072038 | ||
Model for the regulation of size in the wing imaginal disc of Drosophila | Q47301535 | ||
Actin and serum response factor transduce physical cues from the microenvironment to regulate epidermal stem cell fate decisions | Q48532732 | ||
Tensile forces govern germ-layer organization in zebrafish. | Q51961232 | ||
The Salvador partner Hippo promotes apoptosis and cell-cycle exit in Drosophila. | Q52100108 | ||
The Crumbs complex couples cell density sensing to Hippo-dependent control of the TGF-β-SMAD pathway. | Q52605847 | ||
Lgl, aPKC, and Crumbs regulate the Salvador/Warts/Hippo pathway through two distinct mechanisms. | Q52704046 | ||
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. | Q53956406 | ||
Engineering cell shape and function | Q72393350 | ||
Unraveling the microenvironmental influences on the normal mammary gland and breast cancer | Q28473677 | ||
Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size | Q28507019 | ||
Mammalian Tead proteins regulate cell proliferation and contact inhibition as transcriptional mediators of Hippo signaling | Q28507203 | ||
The Hippo signaling pathway components Lats and Yap pattern Tead4 activity to distinguish mouse trophectoderm from inner cell mass | Q28508262 | ||
YAP1 increases organ size and expands undifferentiated progenitor cells | Q28592519 | ||
Actin dynamics control SRF activity by regulation of its coactivator MAL | Q28646140 | ||
Crumbs regulates Salvador/Warts/Hippo signaling in Drosophila via the FERM-domain protein Expanded | Q28752559 | ||
Reversion of the malignant phenotype of human breast cells in three-dimensional culture and in vivo by integrin blocking antibodies | Q29614313 | ||
Geometric control of cell life and death | Q29615213 | ||
Role of YAP/TAZ in mechanotransduction | Q29615411 | ||
Local force and geometry sensing regulate cell functions | Q29616036 | ||
Growth factors, matrices, and forces combine and control stem cells | Q29616603 | ||
Cell adhesion: integrating cytoskeletal dynamics and cellular tension | Q29618066 | ||
Elucidation of a universal size-control mechanism in Drosophila and mammals | Q29618935 | ||
The Drosophila Mst ortholog, hippo, restricts growth and cell proliferation and promotes apoptosis | Q29619851 | ||
hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts | Q29620457 | ||
How we are shaped: the biomechanics of gastrulation | Q30310766 | ||
Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. | Q30355361 | ||
A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration | Q30422818 | ||
Integrins and extracellular matrix in mechanotransduction | Q30423615 | ||
Mechanotransduction in vascular physiology and atherogenesis | Q30439086 | ||
E-cadherin engagement stimulates proliferation via Rac1 | Q30444212 | ||
Emergent patterns of growth controlled by multicellular form and mechanics | Q30447085 | ||
Collective and single cell behavior in epithelial contact inhibition. | Q30504689 | ||
Determination of mechanical stress distribution in Drosophila wing discs using photoelasticity | Q33347817 | ||
Mechanochemical control of mesenchymal condensation and embryonic tooth organ formation | Q33390446 | ||
Beta1 integrin-mediated adhesion signalling is essential for epidermal progenitor cell expansion | Q33441380 | ||
alpha-Catenin as a tension transducer that induces adherens junction development | Q33572769 | ||
Cell shape controls terminal differentiation of human epidermal keratinocytes | Q33635811 | ||
The role of mechanical forces in the torsional component of cardiac looping | Q33723551 | ||
Kibra is a regulator of the Salvador/Warts/Hippo signaling network | Q33754234 | ||
Disruption of the talin gene arrests mouse development at the gastrulation stage | Q33925712 | ||
Mechanical tugging force regulates the size of cell-cell junctions | Q33933194 | ||
The apical transmembrane protein Crumbs functions as a tumor suppressor that regulates Hippo signaling by binding to Expanded | Q33934781 | ||
Loss of the Drosophila cell polarity regulator Scribbled promotes epithelial tissue overgrowth and cooperation with oncogenic Ras-Raf through impaired Hippo pathway signaling | Q34034164 | ||
The Merlin/NF2 tumor suppressor functions through the YAP oncoprotein to regulate tissue homeostasis in mammals | Q34077795 | ||
Linking actin dynamics and gene transcription to drive cellular motile functions | Q34111717 | ||
The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila | Q34115445 | ||
Mechanotransduction in development: a growing role for contractility | Q34186278 | ||
Extracellular-matrix tethering regulates stem-cell fate | Q34277544 | ||
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis | Q34474913 | ||
Regulation of Hippo signaling by Jun kinase signaling during compensatory cell proliferation and regeneration, and in neoplastic tumors. | Q34570927 | ||
Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin | Q34573137 | ||
Hippo signaling: growth control and beyond | Q34625638 | ||
Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling. | Q34727905 | ||
Mechanical integration of actin and adhesion dynamics in cell migration | Q34990511 | ||
Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK-ERK linkage | Q35007822 | ||
Mst1 and Mst2 protein kinases restrain intestinal stem cell proliferation and colonic tumorigenesis by inhibition of Yes-associated protein (Yap) overabundance | Q35621419 | ||
The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma | Q35642059 | ||
Tumor suppression by cell competition through regulation of the Hippo pathway | Q35673635 | ||
Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis | Q35674584 | ||
On the mechanism of wing size determination in fly development | Q35676666 | ||
E-cadherin null mutant embryos fail to form a trophectoderm epithelium | Q35691712 | ||
Epithelial machines that shape the embryo | Q35740301 | ||
Roles for laminin in embryogenesis: exencephaly, syndactyly, and placentopathy in mice lacking the laminin alpha5 chain | Q36255943 | ||
Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments | Q36322021 | ||
In vivo regulation of Yorkie phosphorylation and localization. | Q36663448 | ||
Polarity regulators and the control of epithelial architecture, cell migration, and tumorigenesis. | Q36881687 | ||
A tense situation: forcing tumour progression | Q37112264 | ||
Mechanotransduction gone awry | Q37158222 | ||
Emergence of patterned stem cell differentiation within multicellular structures | Q37218882 | ||
In vivo analysis of Yorkie phosphorylation sites. | Q37239572 | ||
Hematopoietic stem cell development is dependent on blood flow. | Q37294702 | ||
Biomechanical forces promote embryonic haematopoiesis | Q37436209 | ||
Mechanisms by which the extracellular matrix and integrin signaling act to regulate the switch between tumor suppression and tumor promotion | Q37450854 | ||
Cytoskeletal control of growth and cell fate switching | Q37594290 | ||
Regulation of organ growth by morphogen gradients | Q37698263 | ||
Upstream regulation of the hippo size control pathway | Q37771533 | ||
Dynamic interplay between the collagen scaffold and tumor evolution | Q37786073 | ||
Cell-extracellular matrix interactions in normal and diseased skin | Q37858332 | ||
P433 | issue | 9 | |
P921 | main subject | cytoskeleton | Q154626 |
P304 | page(s) | 591-600 | |
P577 | publication date | 2012-08-16 | |
P1433 | published in | Nature Reviews Molecular Cell Biology | Q1573120 |
P1476 | title | Transduction of mechanical and cytoskeletal cues by YAP and TAZ | |
P478 | volume | 13 |
Q38721887 | 3D Protein Dynamics in the Cell Nucleus |
Q38445593 | 8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging. |
Q37041929 | A Computational Model of YAP/TAZ Mechanosensing |
Q37679659 | A ROR1-HER3-lncRNA signalling axis modulates the Hippo-YAP pathway to regulate bone metastasis. |
Q26782842 | A Review: Molecular Aberrations within Hippo Signaling in Bone and Soft-Tissue Sarcomas |
Q54976505 | A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease. |
Q35829995 | A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis |
Q36373479 | A mathematical model of mechanotransduction reveals how mechanical memory regulates mesenchymal stem cell fate decisions. |
Q92437764 | A microphysiological model of the bronchial airways reveals the interplay of mechanical and biochemical signals in bronchospasm |
Q60920444 | A prospect of cell immortalization combined with matrix microenvironmental optimization strategy for tissue engineering and regeneration |
Q35236353 | AMPK modulates Hippo pathway activity to regulate energy homeostasis |
Q38814316 | Acoustic tweezing cytometry enhances osteogenesis of human mesenchymal stem cells through cytoskeletal contractility and YAP activation. |
Q28533309 | Actin cytoskeleton regulates Hippo signaling |
Q35868895 | Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation |
Q38889995 | Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking |
Q38866742 | Activation of Yes-Associated Protein in Low-Grade Meningiomas Is Regulated by Merlin, Cell Density, and Extracellular Matrix Stiffness |
Q39439075 | Actomyosin contractility and collective migration: may the force be with you. |
Q83229378 | Actomyosin regulation by Eph receptor signaling couples boundary cell formation to border sharpness |
Q87990980 | Actomyosin-Mediated Tension Orchestrates Uncoupled Respiration in Adipose Tissues |
Q42364600 | Adaptation trajectories during adhesion and spreading affect future cell states. |
Q30278951 | Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway |
Q35819661 | Aerobic glycolysis tunes YAP/TAZ transcriptional activity |
Q34004237 | Age-related dysfunction in mechanotransduction impairs differentiation of human mammary epithelial progenitors |
Q34807247 | Alpha-catenins control cardiomyocyte proliferation by regulating Yap activity |
Q36132153 | Amotl2a interacts with the Hippo effector Yap1 and the Wnt/β-catenin effector Lef1 to control tissue size in zebrafish. |
Q33604410 | Angiomotins link F-actin architecture to Hippo pathway signaling |
Q38937708 | Arhgef7 promotes activation of the Hippo pathway core kinase Lats |
Q41850821 | Arp2/3 complex function in the epidermis |
Q47993375 | Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2. |
Q37595529 | Augmentation of integrin-mediated mechanotransduction by hyaluronic acid. |
Q38364631 | Biomechanical and biochemical remodeling of stromal extracellular matrix in cancer |
Q38957544 | Biomechanical relationships between the corneal endothelium and Descemet's membrane. |
Q38237390 | Biomechanics of TGFβ-induced epithelial-mesenchymal transition: implications for fibrosis and cancer |
Q64281693 | CRISPR-Mediated Approaches to Regulate YAP/TAZ Levels |
Q51839909 | CTHRC1 promotes osteogenic differentiation of periodontal ligament stem cells by regulating TAZ. |
Q30830997 | Calcium-mediated actin reset (CaAR) mediates acute cell adaptations |
Q42282668 | Cancer-associated fibroblasts support vascular growth through mechanical force. |
Q36632955 | Cell Competition Drives the Growth of Intestinal Adenomas in Drosophila |
Q39363466 | Cell Junctions in Hippo Signaling |
Q47589646 | Cell contact and pressure control of YAP localization and clustering revealed by super-resolution imaging |
Q46121134 | Cell fate decisions: emerging roles for metabolic signals and cell morphology |
Q33920044 | Cell mechanics: a dialogue |
Q35236726 | Cell shape and the microenvironment regulate nuclear translocation of NF-κB in breast epithelial and tumor cells |
Q44462958 | Cell signalling: A new Hippo pathway component |
Q90836224 | Centrosome anchoring regulates progenitor properties and cortical formation |
Q37409421 | Collective polarization model for gradient sensing via Dachsous-Fat intercellular signaling. |
Q42380391 | Combinatorial Microenvironments Impose a Continuum of Cellular Responses to a Single Pathway-Targeted Anti-cancer Compound |
Q27014904 | Concise review: growing hearts in the right place: on the design of biomimetic materials for cardiac stem cell differentiation |
Q34371318 | Concise review: hurdles in a successful example of limbal stem cell-based regenerative medicine. |
Q34735035 | Concise reviews: In vitro-produced pancreas organogenesis models in three dimensions: self-organization from few stem cells or progenitors. |
Q26785528 | Connections between cadherin-catenin proteins, spindle misorientation, and cancer |
Q28833739 | Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3 |
Q90597451 | Control of cellular responses to mechanical cues through YAP/TAZ regulation |
Q35663912 | Control of organ growth by patterning and hippo signaling in Drosophila. |
Q47619053 | Control of the Osteoblast Lineage by Mitogen-Activated Protein Kinase Signaling |
Q35973348 | Cooperation of the BTB-Zinc finger protein, Abrupt, with cytoskeletal regulators in Drosophila epithelial tumorigenesis |
Q38965753 | Cytokinesis failure triggers hippo tumor suppressor pathway activation. |
Q38626767 | Cytoskeletal signaling in TGFβ-induced epithelial-mesenchymal transition |
Q42721563 | Cytoskeletal tension inhibits Hippo signaling through an Ajuba-Warts complex |
Q55330291 | Decellularized Hydrogels in Bone Tissue Engineering: A Topical Review. |
Q30275987 | Deregulation of the Hippo pathway in mouse mammary stem cells promotes mammary tumorigenesis |
Q51099747 | Designer matrices for intestinal stem cell and organoid culture. |
Q50703080 | Developmental biology: Mechanics in the embryo. |
Q36216947 | Differences in the Mechanical Properties of the Developing Cerebral Cortical Proliferative Zone between Mice and Ferrets at both the Tissue and Single-Cell Levels |
Q42029238 | Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition |
Q37044390 | Discriminating the Independent Influence of Cell Adhesion and Spreading Area on Stem Cell Fate Determination Using Micropatterned Surfaces |
Q98471219 | Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi |
Q57294194 | Distinct roles of VE-cadherin for development and maintenance of specific lymph vessel beds |
Q48257593 | Drosophila Big bang regulates the apical cytocortex and wing growth through junctional tension. |
Q37701398 | Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. |
Q39115697 | Dynamic regulation of nuclear architecture and mechanics-a rheostatic role for the nucleus in tailoring cellular mechanosensitivity. |
Q92633600 | Dysfunctional Mechanotransduction through the YAP/TAZ/Hippo Pathway as a Feature of Chronic Disease |
Q45929106 | Dystrophin-glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation. |
Q88742268 | E-cadherin in contact inhibition and cancer |
Q90721946 | EGF Receptor-Dependent YAP Activation Is Important for Renal Recovery from AKI |
Q90929833 | EWS-FLI1-mediated tenascin-C expression promotes tumour progression by targeting MALAT1 through integrin α5β1-mediated YAP activation in Ewing sarcoma |
Q37093582 | Early responses of vascular endothelial cells to topographic cues |
Q47408420 | Effect of the Scaffold Microenvironment on Cell Polarizability and Capacitance Determined by Probabilistic Computations |
Q41544490 | Elements of the niche for adult stem cell expansion |
Q92669325 | Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling |
Q35849118 | Endosomal regulation of contact inhibition through the AMOT:YAP pathway. |
Q41864998 | Endothelial basement membrane laminin 511 is essential for shear stress response |
Q38423843 | Endothelial cell regulation of pulmonary vascular tone, inflammation, and coagulation |
Q48096975 | Endothelial-to-mesenchymal transition in cardiovascular diseases: Developmental signaling pathways gone awry |
Q27006477 | Engaged for survival: From cadherin ligation to STAT3 activation |
Q38556950 | Engineering nanoscale stem cell niche: direct stem cell behavior at cell-matrix interface. |
Q47247113 | Epigenetic Erasing and Pancreatic Differentiation of Dermal Fibroblasts into Insulin-Producing Cells are Boosted by the Use of Low-Stiffness Substrate |
Q37736438 | Epithelial tension in the second heart field promotes mouse heart tube elongation. |
Q99417187 | Establishment of a relationship between blastomere geometry and YAP localisation during compaction |
Q27334965 | Evolution of the fish heart by sub/neofunctionalization of an elastin gene. |
Q42003431 | Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells. |
Q52709138 | Expression pattern of YAP and TAZ during orthodontic tooth movement in rats. |
Q38195538 | Extra- and intracellular factors regulating cardiomyocyte proliferation in postnatal life. |
Q35742523 | Extracellular Matrix Stiffness Regulates Osteogenic Differentiation through MAPK Activation |
Q34647254 | Extracellular matrix elasticity and topography: material-based cues that affect cell function via conserved mechanisms |
Q38177980 | Extracellular matrix: a dynamic microenvironment for stem cell niche |
Q35176181 | FGF8 promotes colorectal cancer growth and metastasis by activating YAP1. |
Q27332286 | FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature |
Q58799822 | FSP1-positive fibroblasts are adipogenic niche and regulate adipose homeostasis |
Q38793478 | Fascin 1 promoted the growth and migration of non-small cell lung cancer cells by activating YAP/TEAD signaling |
Q41876738 | Fat/Dachsous Signaling Promotes Drosophila Wing Growth by Regulating the Conformational State of the NDR Kinase Warts |
Q38541062 | Forcing cells into shape: the mechanics of actomyosin contractility |
Q26866255 | From tissue mechanics to transcription factors |
Q41808566 | G protein-coupled receptors engage the mammalian Hippo pathway through F-actin: F-Actin, assembled in response to Galpha12/13 induced RhoA-GTP, promotes dephosphorylation and activation of the YAP oncogene |
Q34780816 | Global deletion of Ankrd1 results in a wound-healing phenotype associated with dermal fibroblast dysfunction |
Q37598468 | Glucocorticoid receptor signalling activates YAP in breast cancer |
Q42801892 | High levels of the type III inorganic phosphate transporter PiT1 (SLC20A1) can confer faster cell adhesion |
Q38802773 | Hijacking GPCRs by viral pathogens and tumor |
Q50176302 | Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration |
Q41924729 | Hippo pathway deficiency reverses systolic heart failure after infarction. |
Q37117699 | Hippo pathway effector Yap promotes cardiac regeneration |
Q38283345 | Hippo signaling in stress response and homeostasis maintenance |
Q37545029 | Hippo signaling interactions with Wnt/β-catenin and Notch signaling repress liver tumorigenesis |
Q24338421 | Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer |
Q33819083 | Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry. |
Q52726945 | Hippo-yap signaling in ocular development and disease. |
Q28088294 | Hippo/YAP pathway for targeted therapy |
Q57253769 | Hippo/YAP signaling pathway mitigates blood-brain barrier disruption after cerebral ischemia/reperfusion injury |
Q47100686 | Homeostatic Control of Hpo/MST Kinase Activity through Autophosphorylation-Dependent Recruitment of the STRIPAK PP2A Phosphatase Complex |
Q92409829 | Hyaluronan Disrupts Cardiomyocyte Organization within 3D Fibrin-Based Hydrogels |
Q47095212 | Hyaluronic acid enhances cell migration and invasion via the YAP1/TAZ-RHAMM axis in malignant pleural mesothelioma |
Q34493871 | Identification of Happyhour/MAP4K as Alternative Hpo/Mst-like Kinases in the Hippo Kinase Cascade |
Q27003084 | Importance of the stem cell microenvironment for ophthalmological cell-based therapy |
Q47664161 | In Vitro Validation of the Hippo Pathway as a Pharmacological Target for Canine Mammary Gland Tumors. |
Q37528252 | Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. |
Q55174101 | Incorporating mechanical strain in organs-on-a-chip: Lung and skin. |
Q35005633 | Increased expression of Yes-associated protein 1 in hepatocellular carcinoma with stemness and combined hepatocellular-cholangiocarcinoma |
Q90788861 | Induction of store-operated calcium entry (SOCE) suppresses glioblastoma growth by inhibiting the Hippo pathway transcriptional coactivators YAP/TAZ |
Q54110206 | Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth. |
Q92592954 | Integrin α5β1 regulates PP2A complex assembly through PDE4D in atherosclerosis |
Q51281265 | Integrin-YAP/TAZ-JNK cascade mediates atheroprotective effect of unidirectional shear flow. |
Q39139446 | Intra-tumor heterogeneity from a cancer stem cell perspective. |
Q38940169 | Intranuclear Actin Regulates Osteogenesis |
Q35024088 | Intraovarian control of early folliculogenesis |
Q38816108 | Intrinsic and extrinsic regulatory mechanisms are required to form and maintain a lens of the correct size and shape |
Q38630257 | Jasplakinolide induces primary cilium formation through cell rounding and YAP inactivation |
Q52678421 | Kindlin-2 regulates mesenchymal stem cell differentiation through control of YAP1/TAZ. |
Q87415590 | LIF-ting Hippo averts metastasis |
Q90221657 | Lens Stretching Modulates Lens Epithelial Cell Proliferation via YAP Regulation |
Q50131782 | Linking Extracellular Matrix Agrin to the Hippo Pathway in Liver Cancer and Beyond. |
Q91354923 | Localization of YAP activity in developing skeletal rudiments is responsive to mechanical stimulation |
Q28268117 | MAP4K family kinases act in parallel to MST1/2 to activate LATS1/2 in the Hippo pathway |
Q38724065 | MRTF potentiates TEAD-YAP transcriptional activity causing metastasis. |
Q47094065 | Machine Learning for Nuclear Mechano-Morphometric Biomarkers in Cancer Diagnosis |
Q90263519 | Macromolecular crowding tunes 3D collagen architecture and cell morphogenesis |
Q55318101 | Mandibular anterior crowding: normal or pathological? |
Q60300685 | Mathematical-model-guided development of full-thickness epidermal equivalent |
Q38863026 | Mechanical and structural comparison between primary tumor and lymph node metastasis cells in colorectal cancer. |
Q38653648 | Mechanical control of cardiac myofibroblasts |
Q42560237 | Mechanical control of epithelial lumen formation. |
Q48183570 | Mechanical cue-induced YAP instructs Skp2-dependent cell cycle exit and oncogenic signaling. |
Q38235824 | Mechanical force sensing in tissues |
Q47955039 | Mechanical influence of tissue culture plates and extracellular matrix on mesenchymal stem cell behavior: A topical review. |
Q33650895 | Mechanical memory and dosing influence stem cell fate |
Q90202134 | Mechanically tunable coaxial electrospun models of YAP/TAZ mechanoresponse and IGF-1R activation in osteosarcoma |
Q49919334 | Mechanistic insight into contextual TGF-β signaling. |
Q52374735 | Mechano-growth factor protects against mechanical overload induced damage and promotes migration of growth plate chondrocytes through RhoA/YAP pathway. |
Q97529734 | Mechano-modulatory synthetic niches for liver organoid derivation |
Q64917063 | Mechanobiological Feedback in Pulmonary Vascular Disease. |
Q47738846 | Mechanobiology of YAP and TAZ in physiology and disease. |
Q26740308 | Mechanoregulation of Wound Healing and Skin Homeostasis |
Q38651379 | Mechanoresponsive stem cells to target cancer metastases through biophysical cues. |
Q39043810 | Mechanosensing by the nucleus: From pathways to scaling relationships. |
Q64103283 | Mechanotransduction and Cytoskeleton Remodeling Shaping YAP1 in Gastric Tumorigenesis |
Q38202790 | Mechanotransduction and fibrosis. |
Q48260543 | MicroRNA-21 preserves the fibrotic mechanical memory of mesenchymal stem cells. |
Q36455404 | Microenvironment rigidity modulates responses to the HER2 receptor tyrosine kinase inhibitor lapatinib via YAP and TAZ transcription factors |
Q55364065 | Mitotic polarization of transcription factors during asymmetric division establishes fate of forming cancer cells. |
Q51139035 | Modulation of collective cell behaviour by geometrical constraints. |
Q47584927 | Modulation of microenvironment for controlling the fate of periodontal ligament cells: the role of Rho/ROCK signaling and cytoskeletal dynamics |
Q91557750 | Molecular mechanisms of arrhythmogenic cardiomyopathy |
Q92875002 | Molecular-Level Interactions between Engineered Materials and Cells |
Q88637038 | Multifaceted regulation and functions of YAP/TAZ in tumors (Review) |
Q28817567 | Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion |
Q38551979 | Nanomechanics of Cells and Biomaterials Studied by Atomic Force Microscopy |
Q35379721 | Nanotopographical Surfaces for Stem Cell Fate Control: Engineering Mechanobiology from the Bottom |
Q33804099 | Nanotopological plate stimulates osteogenic differentiation through TAZ activation |
Q48160741 | Neural Crest Stem-Like Cells Non-genetically Induced from Human Gingiva-Derived Mesenchymal Stem Cells Promote Facial Nerve Regeneration in Rats |
Q36288449 | Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration |
Q28395671 | New functions for alpha-catenins in health and disease: from cancer to heart regeneration |
Q37157064 | Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription |
Q30845083 | Notch and Hippo signaling converge on Strawberry Notch 1 (Sbno1) to synergistically activate Cdx2 during specification of the trophectoderm |
Q102141559 | Nuclear exclusion of YAP exacerbates podocyte apoptosis and disease progression in Adriamycin-induced focal segmental glomerulosclerosis |
Q50602081 | Optical sensing of mechanical pressure based on diffusion measurement in polyacrylamide cell-like barometers. |
Q57022676 | Orthogonal programming of heterogeneous micro-mechano-environments and geometries in three-dimensional bio-stereolithography |
Q28542439 | Osteoblast-specific deletion of Pkd2 leads to low-turnover osteopenia and reduced bone marrow adiposity |
Q36647912 | PML Surfs into HIPPO Tumor Suppressor Pathway. |
Q92959992 | Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis |
Q89698064 | Paracrine Signaling from Breast Cancer Cells Causes Activation of ID4 Expression in Tumor-Associated Macrophages |
Q38196786 | Paracrine cellular and extracellular matrix interactions with mesenchymal progenitors during pulmonary alveolar septation. |
Q28082204 | Physiological mechanisms and therapeutic potential of bone mechanosensing. |
Q90422674 | Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin |
Q89982448 | Pits and CtBP Control Tissue Growth in Drosophila melanogaster with the Hippo Pathway Transcription Repressor, Tgi |
Q47159490 | Podocalyxin-Like Protein 1 Regulates TAZ Signaling and Stemness Properties in Colon Cancer |
Q34352631 | Polarity-dependent distribution of angiomotin localizes Hippo signaling in preimplantation embryos. |
Q49593669 | Potential microRNA-related Targets for Therapeutic Intervention with Ovarian Cancer Metastasis |
Q38119789 | Premature lung aging and cellular senescence in the pathogenesis of idiopathic pulmonary fibrosis and COPD/emphysema |
Q38730228 | Prostaglandin E2 Activates YAP and a Positive-Signaling Loop to Promote Colon Regeneration After Colitis but Also Carcinogenesis in Mice |
Q36532532 | Proteomic analysis of integrin-associated complexes from mesenchymal stem cells |
Q59050629 | RAP2 mediates mechanoresponses of the Hippo pathway |
Q30361921 | RNAi screens for Rho GTPase regulators of cell shape and YAP/TAZ localisation in triple negative breast cancer. |
Q58763421 | Rapid coupling between gravitational forces and the transcriptome in human myelomonocytic U937 cells |
Q38132299 | Regulation and functions of mammalian LATS/NDR kinases: looking beyond canonical Hippo signalling |
Q47653487 | Regulation of HC11 mouse breast epithelial cell differentiation by the E-cadherin/Rac axis |
Q34375115 | Regulation of YAP by mTOR and autophagy reveals a therapeutic target of tuberous sclerosis complex |
Q34160947 | Regulation of YAP by mechanical strain through Jnk and Hippo signaling |
Q34700159 | Regulation of fibrochondrogenesis of mesenchymal stem cells in an integrated microfluidic platform embedded with biomimetic nanofibrous scaffolds |
Q38676887 | Regulation of mesenchymal stem cell 3D microenvironment: From macro to microfluidic bioreactors |
Q37593084 | Regulation of the Hippo pathway and implications for anticancer drug development |
Q41775151 | Regulation of tissue fibrosis by the biomechanical environment |
Q60922756 | Remodeling the Microenvironment before Occurrence and Metastasis of Cancer |
Q38193984 | Rho, nuclear actin, and actin-binding proteins in the regulation of transcription and gene expression. |
Q36070420 | RhoA deficiency disrupts podocyte cytoskeleton and induces podocyte apoptosis by inhibiting YAP/dendrin signal |
Q57027553 | Role of Extracellular Matrix in Development and Cancer Progression |
Q24306307 | Role of TAZ as mediator of Wnt signaling |
Q92081710 | Role of Tricellular Tight Junction Protein Lipolysis-Stimulated Lipoprotein Receptor (LSR) in Cancer Cells |
Q38622448 | Role of YAP/TAZ in cell-matrix adhesion-mediated signalling and mechanotransduction |
Q39003420 | Role of YAP/TAZ transcriptional regulators in resistance to anti-cancer therapies |
Q38971446 | Role of Yes-associated protein in cancer: An update |
Q38341378 | Roles of the Hippo pathway in lung development and tumorigenesis |
Q39084479 | Roles of the cytoskeleton, cell adhesion and rho signalling in mechanosensing and mechanotransduction. |
Q39031292 | S100A1 and S100B: Calcium Sensors at the Cross-Roads of Multiple Chondrogenic Pathways |
Q37437428 | S100A7 induction is repressed by YAP via the Hippo pathway in A431 cells |
Q33648661 | S100A7 promotes lung adenocarcinoma to squamous carcinoma transdifferentiation, and its expression is differentially regulated by the Hippo-YAP pathway in lung cancer cells |
Q37421179 | Scale Invariant Disordered Nanotopography Promotes Hippocampal Neuron Development and Maturation with Involvement of Mechanotransductive Pathways. |
Q41429732 | Schwann cell development, maturation and regeneration: a focus on classic and emerging intracellular signaling pathways |
Q36340162 | Screening cell mechanotype by parallel microfiltration |
Q37713618 | Screening with a novel cell-based assay for TAZ activators identifies a compound that enhances myogenesis in C2C12 cells and facilitates muscle repair in a muscle injury model |
Q41472473 | Scribble acts in the Drosophila fat-hippo pathway to regulate warts activity |
Q89697056 | Shaping Pancreatic β-Cell Differentiation and Functioning: The Influence of Mechanotransduction |
Q49888206 | Shaping cell fate: influence of topographical substratum properties on embryonic stem cells |
Q35128225 | Shear stress induced by an interstitial level of slow flow increases the osteogenic differentiation of mesenchymal stem cells through TAZ activation |
Q52341747 | Significance of whole-genome duplications on the emergence of evolutionary novelties. |
Q38391096 | Size control: the developmental physiology of body and organ size regulation |
Q89599729 | Skeletal muscle as an experimental model of choice to study tissue aging and rejuvenation |
Q55214898 | Sleeping Beauty and the Microenvironment Enchantment: Microenvironmental Regulation of the Proliferation-Quiescence Decision in Normal Tissues and in Cancer Development. |
Q37161721 | Spatially patterned matrix elasticity directs stem cell fate |
Q34295733 | Stem Cells toward the Future: The Space Challenge |
Q38612551 | Stimulation of Bone Repair with Ultrasound. |
Q38283342 | Structural dissection of Hippo signaling. |
Q52626789 | Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1. |
Q41327484 | Surface Topography Guides Morphology and Spatial Patterning of Induced Pluripotent Stem Cell Colonies |
Q50431861 | TGF-β1 regulates the expression and transcriptional activity of TAZ protein via a Smad3-independent, myocardin-related transcription factor-mediated mechanism |
Q58555364 | TNF-α-Induced YAP/TAZ Activity Mediates Leukocyte-Endothelial Adhesion by Regulating VCAM1 Expression in Endothelial Cells |
Q47267301 | TRIP6 inhibits Hippo signaling in response to tension at adherens junctions. |
Q36568116 | Tead and AP1 Coordinate Transcription and Motility. |
Q89686871 | Tenascin-C Promotes Tumor Cell Migration and Metastasis through Integrin α9β1-Mediated YAP Inhibition |
Q36209802 | The Characteristic of S100A7 Induction by the Hippo-YAP Pathway in Cervical and Glossopharyngeal Squamous Cell Carcinoma |
Q46136392 | The Future of Radiobiology. |
Q57456794 | The Hippo pathway effector Taz is required for cell morphogenesis and fertilization in zebrafish |
Q33937666 | The Hippo pathway in disease and therapy: cancer and beyond |
Q90966566 | The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration |
Q36902243 | The Hippo signal transduction network for exercise physiologists |
Q34376898 | The Hippo signaling pathway interactome |
Q38907037 | The Hippo transducer TAZ promotes epithelial to mesenchymal transition and cancer stem cell maintenance in oral cancer. |
Q30408095 | The Hippo-YAP signaling pathway and contact inhibition of growth |
Q55104007 | The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensis. |
Q36113002 | The cellular mastermind(?)-mechanotransduction and the nucleus |
Q26801427 | The central role of muscle stem cells in regenerative failure with aging |
Q46328640 | The deleterious interplay between tumor epithelia and stroma in cholangiocarcinoma. |
Q49346905 | The history and regulatory mechanism of the Hippo pathway |
Q36002020 | The hnRNP-Htt axis regulates necrotic cell death induced by transcriptional repression through impaired RNA splicing. |
Q38638093 | The interplay between centrosomes and the Hippo tumor suppressor pathway |
Q26751250 | The myofibroblast in wound healing and fibrosis: answered and unanswered questions |
Q38724224 | The nucleus is a conserved mechanosensation and mechanoresponse organelle. |
Q40748577 | The role of the hippo pathway in melanocytes and melanoma |
Q48144535 | The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells. |
Q57169200 | The versatile hippo pathway in oral-maxillofacial development and bone remodeling |
Q92861368 | Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons |
Q58575726 | Tissue engineering the cancer microenvironment-challenges and opportunities |
Q34563167 | Topography design concept of a tissue engineering scaffold for controlling cell function and fate through actin cytoskeletal modulation |
Q93037470 | Toxoplasma gondii Dysregulates Barrier Function and Mechanotransduction Signaling in Human Endothelial Cells |
Q47104051 | Transcriptional integration of mitogenic and mechanical signals by Myc and YAP. |
Q38828186 | Tunable Crosslinked Cell-Derived Extracellular Matrix Guides Cell Fate. |
Q59790779 | Type I collagen deposition via osteoinduction ameliorates YAP/TAZ activity in 3D floating culture clumps of mesenchymal stem cell/extracellular matrix complexes |
Q63681550 | UBTD1 is a mechano-regulator controlling cancer aggressiveness |
Q41478438 | Uncovering the effect of low-frequency static magnetic field on tendon-derived cells: from mechanosensing to tenogenesis |
Q49346894 | Upstream paths for Hippo signaling in Drosophila organ development |
Q55513246 | WDR1 Promotes Cell Growth and Migration and Contributes to Malignant Phenotypes of Non-small Cell Lung Cancer through ADF/cofilin-mediated Actin Dynamics. |
Q34339790 | Willin, an upstream component of the hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts |
Q63408561 | YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6 |
Q52666551 | YAP and ERK mediated mechanical strain-induced cell cycle progression through RhoA and cytoskeletal dynamics in rat growth plate chondrocytes. |
Q52719468 | YAP and TAZ are dispensable for physiological and malignant haematopoiesis. |
Q90714387 | YAP and TAZ are distinct effectors of corneal myofibroblast transformation |
Q89013115 | YAP and TAZ are essential for basal and squamous cell carcinoma initiation |
Q28828570 | YAP and TAZ control peripheral myelination and the expression of laminin receptors in Schwann cells |
Q28085636 | YAP and TAZ: a nexus for Hippo signaling and beyond |
Q89514112 | YAP and the RhoC regulator ARHGAP18, are required to mediate flow-dependent endothelial cell alignment |
Q92091876 | YAP as a key regulator of adipo-osteogenic differentiation in human MSCs |
Q39091458 | YAP is essential for 3D organogenesis withstanding gravity |
Q26766774 | YAP-Mediated Mechanotransduction in Skeletal Muscle |
Q46868332 | YAP-mediated regulation of the chondrogenic phenotype in response to matrix elasticity |
Q54977387 | YAP/TAZ Activation as a Target for Treating Metastatic Cancer. |
Q26748704 | YAP/TAZ as therapeutic targets in cancer |
Q38864941 | YAP/TAZ at the Roots of Cancer. |
Q92932409 | YAP/TAZ direct commitment and maturation of lymph node fibroblastic reticular cells |
Q104802882 | YAP/TAZ inhibition reduces metastatic potential of Ewing sarcoma cells |
Q41957468 | YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate |
Q55331948 | YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts. |
Q43007023 | YAP/TAZ regulates sprouting angiogenesis and vascular barrier maturation |
Q92406899 | YAP1 mediates survival of ALK-rearranged lung cancer cells treated with alectinib via pro-apoptotic protein regulation |
Q90504035 | Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation |
Q57471357 | Yes-associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) mediate cell density-dependent proinflammatory responses |
Q35666856 | Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells |
Q48157276 | Yes-associated protein 1 promotes the differentiation and mineralization of cementoblast. |
Q89595495 | Yorkie Growth-Promoting Activity Is Limited by Atg1-Mediated Phosphorylation |
Q41047992 | Yorkie is required to restrict the injury responses in planarians |
Q47149836 | Yorkie regulates epidermal wound healing in Drosophila larvae independently of cell proliferation and apoptosis. |
Q36768308 | Zyxin-Siah2-Lats2 axis mediates cooperation between Hippo and TGF-β signalling pathways |
Q52752350 | [Mechanics of inner cell mass formation]. |
Q36898504 | cAMP/PKA signalling reinforces the LATS-YAP pathway to fully suppress YAP in response to actin cytoskeletal changes. |
Q57283468 | inactivation reveals hippo function in alveolar type I cell differentiation during lung transition to air breathing |
Q37295543 | miR-509-3p is clinically significant and strongly attenuates cellular migration and multi-cellular spheroids in ovarian cancer. |
Q89542503 | β-Catenin Preserves the Stem State of Murine Bone Marrow Stromal Cells Through Activation of EZH2 |
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