The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations and

scientific article published in Journal of Biological Chemistry

The scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations and is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.RA118.003908
P932PMC publication ID6231134
P698PubMed publication ID30242130

P50authorLe ShenQ59819330
Jerrold R TurnerQ86700424
P2093author name stringAlan S Fanning
Wangsun Choi
Gurminder Singh
Wei-Ting Kuo
Matthew A Odenwald
Anne Sailer
Yitang Wang
P2860cites workIntestinal brush border assembly driven by protocadherin-based intermicrovillar adhesionQ24294411
The gap junction protein connexin43 interacts with the second PDZ domain of the zona occludens-1 proteinQ24324462
Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteinsQ24336753
Regulation of PCNA and cyclin D1 expression and epithelial morphogenesis by the ZO-1-regulated transcription factor ZONAB/DbpAQ24548016
Direct association of occludin with ZO-1 and its possible involvement in the localization of occludin at tight junctionsQ24672971
Involvement of ZO-1 in Cadherin-based Cell Adhesion through Its Direct Binding to α Catenin and Actin FilamentsQ24678389
Arp2/3-mediated F-actin formation controls regulated exocytosis in vivoQ27340369
Domain-swapped dimerization of ZO-1 PDZ2 generates specific and regulatory connexin43-binding sitesQ27651231
Dissecting temporal and spatial control of cytokinesis with a myosin II InhibitorQ28183531
Mechanism of blebbistatin inhibition of myosin IIQ28267628
Specificity of blebbistatin, an inhibitor of myosin IIQ28293974
Detailed regulatory mechanism of the interaction between ZO-1 PDZ2 and connexin43 revealed by MD simulationsQ28478719
Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctionsQ28511375
Myosin-1a is critical for normal brush border structure and compositionQ28512472
Vinculin directly binds zonula occludens-1 and is essential for stabilizing connexin-43-containing gap junctions in cardiac myocytesQ28592273
Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertensionQ29614247
Self-organizing optic-cup morphogenesis in three-dimensional cultureQ29616181
Dynasore, a cell-permeable inhibitor of dynaminQ29619881
Occludin OCEL-domain interactions are required for maintenance and regulation of the tight junction barrier to macromolecular fluxQ30009590
Epithelial barrier assembly requires coordinated activity of multiple domains of the tight junction protein ZO-1Q30009921
ZO-1 stabilizes the tight junction solute barrier through coupling to the perijunctional cytoskeletonQ30157199
Zonula occludens-1 function in the assembly of tight junctions in Madin-Darby canine kidney epithelial cellsQ30159938
Myosin II directly binds and inhibits Dbl family guanine nucleotide exchange factors: a possible link to Rho family GTPases.Q30433123
Actin depolymerization disrupts tight junctions via caveolae-mediated endocytosisQ30476106
Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesisQ30484554
Dynamin 2 orchestrates the global actomyosin cytoskeleton for epithelial maintenance and apical constrictionQ30492068
Pulsed contractions of an actin-myosin network drive apical constrictionQ30493161
Myosin light chain kinase and Src control membrane dynamics in volume recovery from cell swellingQ30498278
The epithelial barrier is maintained by in vivo tight junction expansion during pathologic intestinal epithelial shedding.Q30499201
Remodeling the zonula adherens in response to tension and the role of afadin in this responseQ30826769
Apical constriction: themes and variations on a cellular mechanism driving morphogenesisQ33570622
Caveolin-1-dependent occludin endocytosis is required for TNF-induced tight junction regulation in vivoQ33788423
MLCK-dependent exchange and actin binding region-dependent anchoring of ZO-1 regulate tight junction barrier functionQ33929240
Cdc42-dependent modulation of tight junctions and membrane protein traffic in polarized Madin-Darby canine kidney cellsQ33944040
Epithelial myosin light chain kinase-dependent barrier dysfunction mediates T cell activation-induced diarrhea in vivoQ34014510
Endocytosis is required for efficient apical constriction during Xenopus gastrulationQ34094358
Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesisQ34212208
Crowding induces live cell extrusion to maintain homeostatic cell numbers in epitheliaQ34268263
Rab GTPase-Myo5B complexes control membrane recycling and epithelial polarization.Q34582966
The enterocyte microvillus is a vesicle-generating organelleQ34989756
A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invaginationQ35534618
Zonula occludens-1 and -2 regulate apical cell structure and the zonula adherens cytoskeleton in polarized epitheliaQ35756679
Mechanism of recruiting Sec6/8 (exocyst) complex to the apical junctional complex during polarization of epithelial cellsQ36012274
Multiple myosins are required to coordinate actin assembly with coat compression during compensatory endocytosisQ36017065
Myosin is involved in postmitotic cell spreadingQ36236105
NH2-terminal deletion of beta-catenin results in stable colocalization of mutant beta-catenin with adenomatous polyposis coli protein and altered MDCK cell adhesionQ36258529
Cargo-selective apical exocytosis in epithelial cells is conducted by Myo5B, Slp4a, Vamp7, and Syntaxin 3.Q36266151
The ZO-1-associated Y-box factor ZONAB regulates epithelial cell proliferation and cell densityQ36322940
The tight junction protein complex undergoes rapid and continuous molecular remodeling at steady stateQ36660697
Deficiency of zonula occludens-1 causes embryonic lethal phenotype associated with defected yolk sac angiogenesis and apoptosis of embryonic cellsQ36678082
Dynamin triple knockout cells reveal off target effects of commonly used dynamin inhibitorsQ37309907
Zonula occludens-1 and -2 are cytosolic scaffolds that regulate the assembly of cellular junctionsQ37524262
Apical constriction: a cell shape change that can drive morphogenesis.Q37596612
ZO-1 interactions with F-actin and occludin direct epithelial polarization and single lumen specification in 3D culture.Q38734544
Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organsQ38906960
Dbl3 drives Cdc42 signaling at the apical margin to regulate junction position and apical differentiationQ39038189
Membrane shaping by actin and myosin during regulated exocytosisQ39325039
Requirement of ZO-1 for the formation of belt-like adherens junctions during epithelial cell polarizationQ39734201
A strategy to identify stable membrane-permeant peptide inhibitors of myosin light chain kinase.Q40419606
Multiple effects of 2,3-butanedione monoximeQ40638370
Isolation and functional characterization of the actin binding region in the tight junction protein ZO-1.Q40700804
A molecular network for de novo generation of the apical surface and lumenQ42116509
Topological defects in epithelia govern cell death and extrusionQ42171388
Cell mechanics and feedback regulation of actomyosin networksQ42173045
Inhibition of actin polymerization by latrunculin A.Q42217562
An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanismQ43812071
2,3-Butanedione monoxime (BDM) as a myosin inhibitorQ44358175
Knockdown of occludin expression leads to diverse phenotypic alterations in epithelial cells.Q45249905
Tension-Dependent Stretching Activates ZO-1 to Control the Junctional Localization of Its InteractorsQ47289479
Lipopolysaccharide-Induced Increase in Intestinal Epithelial Tight Permeability Is Mediated by Toll-Like Receptor 4/Myeloid Differentiation Primary Response 88 (MyD88) Activation of Myosin Light Chain Kinase ExpressionQ47382531
Epithelial Organization: The Gut and BeyondQ47795925
An apical MRCK-driven morphogenetic pathway controls epithelial polarity.Q47927624
Nanoscale Dynamism of Actin Enables Secretory Function in Cytolytic Cells.Q49343640
The tight junction protein occludin and the adherens junction protein alpha-catenin share a common interaction mechanism with ZO-1.Q52941644
A membrane-permeant peptide that inhibits MLC kinase restores barrier function in in vitro models of intestinal disease.Q53965794
Comparison of the effects of 2,3-butanedione monoxime on force production, myosin light chain phosphorylation and chemical energy usage in intact and permeabilized smooth and skeletal muscles.Q54629921
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structureQ57179984
Significance of cell shape in tissue architectureQ59061140
Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylationQ73847660
P433issue45
P407language of work or nameEnglishQ1860
P921main subjectmolecular biologyQ7202
P304page(s)17317-17335
P577publication date2018-09-21
P1433published inJournal of Biological ChemistryQ867727
P1476titleThe scaffolding protein ZO-1 coordinates actomyosin and epithelial apical specializations in vitro and in vivo
P478volume293