The topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates

scientific article published on 17 September 2018

The topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1371/JOURNAL.PGEN.1007674
P932PMC publication ID6160208
P698PubMed publication ID30222730

P50authorSusan SchröpferQ57987557
Frank HartungQ87994311
Annika DornQ90309714
Kristin PappQ91482747
Holger PuchtaQ30533442
P2093author name stringAlexander Knoll
Sarah Röhrig
P2860cites workHuman TOP3: a single-copy gene encoding DNA topoisomerase IIIQ24308917
The Bloom's syndrome gene product is homologous to RecQ helicasesQ24313440
Human GEN1 and the SLX4-associated nucleases MUS81 and SLX1 are essential for the resolution of replication-induced Holliday junctionsQ24337537
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalphaQ24537672
BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediatesQ24544999
Requirement for three novel protein complexes in the absence of the Sgs1 DNA helicase in Saccharomyces cerevisiaeQ24548169
Damage tolerance protein Mus81 associates with the FHA1 domain of checkpoint kinase Cds1Q24551095
Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytesQ24555804
RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stabilityQ24650860
BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasomeQ24650899
The role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase IQ24793994
Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complexQ27664372
Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1Q27681649
A Novel Image-Analysis Toolbox Enabling Quantitative Analysis of Root System ArchitectureQ27709611
Gene Expression Omnibus: NCBI gene expression and hybridization array data repositoryQ27860523
Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thalianaQ27860555
Functional overlap between Sgs1-Top3 and the Mms4-Mus81 endonucleaseQ27935913
The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyraseQ28170377
Multiple mechanisms limit meiotic crossovers: TOP3α and two BLM homologs antagonize crossovers in parallel to FANCMQ28259690
The double-strand-break repair model for recombinationQ28267259
Bloom syndrome: a mendelian prototype of somatic mutational disease.Q52222079
Both CRISPR/Cas-based nucleases and nickases can be used efficiently for genome engineering in Arabidopsis thaliana.Q52423023
Peptide sequencing and site-directed mutagenesis identify tyrosine-319 as the active site tyrosine of Escherichia coli DNA topoisomerase IQ69364371
The galvanization of biology: a growing appreciation for the roles of zincQ70995740
Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNAQ72609734
Topoisomerase 3alpha and RMI1 suppress somatic crossovers and are essential for resolution of meiotic recombination intermediates in Arabidopsis thalianaQ28474239
The Bloom's syndrome helicase suppresses crossing over during homologous recombinationQ29547237
Mus81-Eme1 are essential components of a Holliday junction resolvaseQ29619843
A library of Arabidopsis 35S-cDNA lines for identifying novel mutantsQ30725881
Drosophila melanogaster topoisomerase IIIalpha preferentially relaxes a positively or negatively supercoiled bubble substrate and is essential during developmentQ30842842
Toprim--a conserved catalytic domain in type IA and II topoisomerases, DnaG-type primases, OLD family nucleases and RecR proteinsQ32030823
Topoisomerase IIIalpha and Bloom's helicase can resolve a mobile double Holliday junction substrate through convergent branch migrationQ33250631
Tolerance of dividing cells to replication stress in UVB-irradiated Arabidopsis roots: requirements for DNA translesion polymerases eta and zetaQ33344004
The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thalianaQ33364133
The Arabidopsis BLAP75/Rmi1 homologue plays crucial roles in meiotic double-strand break repairQ33394561
Association of yeast DNA topoisomerase III and Sgs1 DNA helicase: studies of fusion proteins.Q33944291
Processing of joint molecule intermediates by structure-selective endonucleases during homologous recombination in eukaryotesQ34025948
Homologous recombination resolution defect in werner syndromeQ34150355
Identification and characterization of the human mus81-eme1 endonucleaseQ34193657
Mapping the active-site tyrosine of vaccinia virus DNA topoisomerase I.Q34325217
MHF1 plays Fanconi anaemia complementation group M protein (FANCM)-dependent and FANCM-independent roles in DNA repair and homologous recombination in plantsQ34410399
A double Holliday junction dissolvasome comprising BLM, topoisomerase IIIalpha, and BLAP75.Q34510600
A manyfold increase in sister chromatid exchanges in Bloom's syndrome lymphocytesQ35116805
Mammalian DNA topoisomerase IIIalpha is essential in early embryogenesisQ35782855
Development of autoimmunity in mice lacking DNA topoisomerase 3betaQ35839541
Synthetic lethality of Drosophila in the absence of the MUS81 endonuclease and the DmBlm helicase is associated with elevated apoptosis.Q35945625
A new Drosophila gene wh (wuho) with WD40 repeats is essential for spermatogenesis and has maximal expression in hub cellsQ36108362
Two closely related RecQ helicases have antagonistic roles in homologous recombination and DNA repair in Arabidopsis thalianaQ36277053
Structural basis for suppression of hypernegative DNA supercoiling by E. coli topoisomerase IQ36370815
Mutation adjacent to the active site tyrosine can enhance DNA cleavage and cell killing by the TOPRIM Gly to Ser mutant of bacterial topoisomerase I.Q36457138
Defective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3betaQ36516076
The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'?Q36991033
Structural and functional relationships of the XPF/MUS81 family of proteinsQ37179480
Top3β is an RNA topoisomerase that works with fragile X syndrome protein to promote synapse formationQ37368860
The RTR complex as caretaker of genome stability and its unique meiotic function in plantsQ37578765
Cytological analysis of Arabidopsis thaliana meiotic chromosomesQ37580803
Deletion of TOP3β, a component of FMRP-containing mRNPs, contributes to neurodevelopmental disordersQ37703015
Topoisomerases and site-specific recombinases: similarities in structure and mechanismQ37810595
Molecular mechanism of double Holliday junction dissolutionQ38233870
The nuclease FAN1 is involved in DNA crosslink repair in Arabidopsis thaliana independently of the nuclease MUS81.Q38300405
Different functions for the domains of the Arabidopsis thaliana RMI1 protein in DNA cross-link repair, somatic and meiotic recombinationQ38313309
Recognition and manipulation of branched DNA by the RusA Holliday junction resolvase of Escherichia coliQ38337262
Identification of active site residues in Escherichia coli DNA topoisomerase I.Q38338658
The role of AtMUS81 in DNA repair and its genetic interaction with the helicase AtRecQ4A.Q39113832
DNA double-chain breaks in recombination of phage lambda and of yeastQ39489899
Functional characterization of Caenorhabditis elegans DNA topoisomerase IIIalphaQ39545837
The top3(+) gene is essential in Schizosaccharomyces pombe and the lethality associated with its loss is caused by Rad12 helicase activityQ39729811
Partial suppression of the fission yeast rqh1(-) phenotype by expression of a bacterial Holliday junction resolvaseQ39958831
Embryonic pattern formation in flowering plantsQ40614016
Defining the roles of the N-terminal region and the helicase activity of RECQ4A in DNA repair and homologous recombination in ArabidopsisQ41891208
Essential functions of C terminus of Drosophila Topoisomerase IIIα in double holliday junction dissolutionQ41891876
RMI1 and TOP3α limit meiotic CO formation through their C-terminal domainsQ42166036
Holliday junction resolvases encoded by homologous rusA genes in Escherichia coli K-12 and phage 82.Q42631152
A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomeraseQ42641816
Roles of SGS1, MUS81, and RAD51 in the repair of lagging-strand replication defects in Saccharomyces cerevisiaeQ42913266
Interchromatid and interhomolog recombination in Arabidopsis thalianaQ44733073
RAD5A, RECQ4A, and MUS81 have specific functions in homologous recombination and define different pathways of DNA repair in Arabidopsis thalianaQ45412951
Two distinct MUS81-EME1 complexes from Arabidopsis process Holliday junctionsQ48070483
The small, versatile pPZP family of Agrobacterium binary vectors for plant transformationQ48079546
Caught with One's Zinc Fingers in the Genome Integrity Cookie Jar.Q49685857
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageJQ1659584
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectArabidopsis thalianaQ158695
molecular biologyQ7202
cancer researchQ3421914
P304page(s)e1007674
P577publication date2018-09-17
P1433published inPLOS GeneticsQ1893441
P1476titleThe topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates
P478volume14

Reverse relations

cites work (P2860)
Q92240524An Arabidopsis FANCJ helicase homologue is required for DNA crosslink repair and rDNA repeat stability
Q91964143DNA Helicases as Safekeepers of Genome Stability in Plants
Q93102659DNA- and DNA-Protein-Crosslink Repair in Plants
Q99546688Whole genome sequencing identifies Allelic Ratio Distortion in sperm involving genes related to spermatogenesis in a swine model

Search more.