Sulforaphane regulates apoptosis- and proliferation‑related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer

Sulforaphane regulates apoptosis- and proliferation‑related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3892/IJMM.2018.3860
P932PMC publication ID6192763
P698PubMed publication ID30226534

P2093author name stringJian Wang
Shi-Feng Kan
Guan-Xing Sun
P2860cites workAnalysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT MethodQ25938999
Dietary factors and epigenetic regulation for prostate cancer preventionQ26991774
Major clinical research advances in gynecologic cancer in 2014Q26992183
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Seromic profiling of ovarian and pancreatic cancerQ33739967
Antileukemic activity of sulforaphane in primary blasts from patients affected by myelo- and lympho-proliferative disorders and in hypoxic conditionsQ33896639
Identification and Management of Women With BRCA Mutations or Hereditary Predisposition for Breast and Ovarian CancerQ34152848
Sulforaphane induces cell cycle arrest and apoptosis in acute lymphoblastic leukemia cellsQ34516308
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouseQ34596182
Multi-targeted prevention of cancer by sulforaphaneQ34781826
Expression of the MT1 melatonin receptor in ovarian cancer cellsQ34835245
Dietary sulforaphane, a histone deacetylase inhibitor for cancer preventionQ35007040
Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cellsQ35109117
Kaempferol inhibits VEGF expression and in vitro angiogenesis through a novel ERK-NFκB-cMyc-p21 pathwayQ35210298
Immunotherapeutic approaches to ovarian cancer treatmentQ35213535
Fertility preservation in female cancer patients: An overviewQ35237851
Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract.Q35386131
Rethinking ovarian cancer: recommendations for improving outcomesQ36050883
Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cellsQ36512713
Epigallocatechin gallate and sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down-regulation.Q36625295
Premature menopauseQ36789707
DNA copy number profiling reveals extensive genomic loss in hereditary BRCA1 and BRCA2 ovarian carcinomas.Q36889676
Deconvoluting the structural and drug-recognition complexity of the G-quadruplex-forming region upstream of the bcl-2 P1 promoterQ36966230
Olaparib: a review of its use as maintenance therapy in patients with ovarian cancerQ38433579
Sulforaphane induces DNA damage and mitotic abnormalities in human osteosarcoma MG-63 cells: correlation with cell cycle arrest and apoptosisQ39036074
Clofarabine, a novel adenosine analogue, reactivates DNA methylation-silenced tumour suppressor genes and inhibits cell growth in breast cancer cells.Q39051145
Selenocystine induces S-phase arrest and apoptosis in human breast adenocarcinoma MCF-7 cells by modulating ERK and Akt phosphorylationQ39923869
Selenocystine induces reactive oxygen species-mediated apoptosis in human cancer cellsQ39977305
Inhibition of cyclin D1 expression by cyclin D1 shRNAs in human oral squamous cell carcinoma cells is associated with increased cisplatin chemosensitivityQ40034367
A critical role of luteolin-induced reactive oxygen species in blockage of tumor necrosis factor-activated nuclear factor-kappaB pathway and sensitization of apoptosis in lung cancer cellsQ40171730
Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cellsQ40375288
Overexpression of cyclin D1 promotes tumor cell growth and confers resistance to cisplatin-mediated apoptosis in an elastase-myc transgene-expressing pancreatic tumor cell lineQ40382268
Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.Q40430279
Sulforaphane targets pancreatic tumour-initiating cells by NF-kappaB-induced antiapoptotic signallingQ46336155
Risk Assessment, Genetic Counseling, and Genetic Testing for BRCA-Related Cancer in Women: U.S. Preventive Services Task Force Recommendation StatementQ54092157
Subcellular Localization and Protein Levels of Cyclin-Dependent Kinase Inhibitor p27 Independently Predict for Survival in Epithelial Ovarian CancerQ57904929
Anti-carcinogenic effects of sulforaphane in association with its apoptosis-inducing and anti-inflammatory properties in human cervical cancer cellsQ85213795
Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by sulforaphaneQ87125582
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectcisplatinQ412415
ovarian cancerQ172341
P304page(s)2447-2458
P577publication date2018-11-01
P1433published inInternational Journal of Molecular MedicineQ6051492
P1476titleSulforaphane regulates apoptosis- and proliferation‑related signaling pathways and synergizes with cisplatin to suppress human ovarian cancer
P478volume42

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cites work (P2860)
Q89510873Molecular Mechanisms of the Anti-Cancer Effects of Isothiocyanates from Cruciferous Vegetables in Bladder Cancer
Q95270493Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects
Q59807366Sulforaphane from Cruciferous Vegetables: Recent Advances to Improve Glioblastoma Treatment
Q92731356The Glucosinolates: A Sulphur Glucoside Family of Mustard Anti-Tumour and Antimicrobial Phytochemicals of Potential Therapeutic Application

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