Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration

scientific article published on 01 August 2018

Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2018.07.029
P932PMC publication ID6155462
P698PubMed publication ID30110642

P50authorClifford J. WoolfQ5132981
Mary C WhitmanQ57179898
Elizabeth B HutchinsonQ48355900
P2093author name stringElizabeth C Engle
Chen Wu
Max A Tischfield
Long Cheng
Elaine Nguyen
Carlo Pierpaoli
Sheena Chew
Yanjie Fan
Shu-Hsien Sheu
Takao Omura
Crystal Hermawan
Alban Latremoliere
Eric A Huebner
Andrew Sheridan
Frederic Latremoliere
Chloe Alexandre
Michelle DeLisle
Sara Golidy
P2860cites workHuman TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidanceQ24294967
Are tubulin isotypes functionally significantQ24622545
Axonal regeneration. Systemic administration of epothilone B promotes axon regeneration after spinal cord injuryQ27331607
Reversal of axonal growth defects in an extraocular fibrosis model by engineering the kinesin-microtubule interfaceQ27342394
Voxel-based morphometry–the methodsQ28138780
Mutations in the neuronal ß-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defectsQ28292823
Identification of conserved isotype-defining variable region sequences for four vertebrate beta tubulin polypeptide classesQ28298601
Differential regulation of beta III and other tubulin genes during peripheral and central neuron developmentQ48410408
Changes in the isotype composition of beta-tubulin delivered to regenerating sensory axons by slow axonal transportQ48831486
Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury.Q51451500
Doublecortin-Like Kinases Promote Neuronal Survival and Induce Growth Cone Reformation via Distinct Mechanisms.Q54236436
Two unique TUBB3 mutations cause both CFEOM3 and malformations of cortical development.Q55122153
Expression of the class III beta-tubulin gene during axonal regeneration of rat dorsal root ganglion neuronsQ70537362
Microtubule stability decreases axon elongation but not axoplasm productionQ71071944
Sensory neurons selectively upregulate synthesis and transport of the beta III-tubulin protein during axonal regenerationQ72575598
Rapid quantification of adult and developing mouse spatial vision using a virtual optomotor systemQ81041523
Injury-Induced HDAC5 Nuclear Export Is Essential for Axon RegenerationQ89001929
Beta tubulin isoforms are not interchangeable for rescuing impaired radial migration due to Tubb3 knockdownQ28301198
Promotion of Functional Nerve Regeneration by Inhibition of Microtubule DetyrosinationQ29013578
Expression of the class III beta-tubulin isotype in developing neurons in culture.Q30434068
Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injuryQ30513561
Using plusTipTracker software to measure microtubule dynamics in Xenopus laevis growth conesQ30589827
Color schemes to represent the orientation of anisotropic tissues from diffusion tensor data: application to white matter fiber tract mapping in the human brainQ30598356
The structured core of human β tubulin confers isotype-specific polymerization propertiesQ30761012
Mass spectrometry analysis of C-terminal posttranslational modifications of tubulinsQ33577598
Distinct roles for secreted semaphorin signaling in spinal motor axon guidanceQ34477943
ATF3 increases the intrinsic growth state of DRG neurons to enhance peripheral nerve regenerationQ34655825
Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brainQ34656983
DR-BUDDI (Diffeomorphic Registration for Blip-Up blip-Down Diffusion Imaging) method for correcting echo planar imaging distortionsQ34857302
Accelerating axonal growth promotes motor recovery after peripheral nerve injury in miceQ35572510
Recognizable cerebellar dysplasia associated with mutations in multiple tubulin genes.Q35679363
Tubulin-tyrosine Ligase (TTL)-mediated Increase in Tyrosinated α-Tubulin in Injured Axons Is Required for Retrograde Injury Signaling and Axon RegenerationQ35860868
Distinct alpha- and beta-tubulin isotypes are required for the positioning, differentiation and survival of neurons: new support for the 'multi-tubulin' hypothesisQ35869187
Microtubule dynamics in vitro are regulated by the tubulin isotype compositionQ35910782
The multitubulin hypothesis revisited: what have we learned?Q36216400
Median and ulnar nerve injuries: a meta-analysis of predictors of motor and sensory recovery after modern microsurgical nerve repair.Q36218170
The role of microtubule dynamics in growth cone motility and axonal growthQ36235154
A novel syndrome caused by the E410K amino acid substitution in the neuronal β-tubulin isotype 3.Q36611419
Mutations in Human Tubulin Proximal to the Kinesin-Binding Site Alter Dynamic Instability at Microtubule Plus- and Minus-EndsQ36800259
Nerve conduction, tactile sensibility, and the electromyogram after suture or compression of peripheral nerve: a longitudinal study in manQ36992724
Resolving bundled microtubules using anti-tubulin nanobodies.Q37031835
The wide spectrum of tubulinopathies: what are the key features for the diagnosis?Q38214584
Glycogen synthase kinase-3beta phosphorylation of MAP1B at Ser1260 and Thr1265 is spatially restricted to growing axons.Q38330149
A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth ProgramQ38973189
Human CFEOM1 mutations attenuate KIF21A autoinhibition and cause oculomotor axon stalling.Q39018528
Sustained axon regeneration induced by co-deletion of PTEN and SOCS3Q39864495
The GSK3-MAP1B pathway controls neurite branching and microtubule dynamicsQ40101847
β-Tubulin mutations that cause severe neuropathies disrupt axonal transportQ40752898
Injury-induced decline of intrinsic regenerative ability revealed by quantitative proteomicsQ42579331
Sustained GSK3 activity markedly facilitates nerve regeneration.Q44773089
Tubulin isoform composition tunes microtubule dynamicsQ47665595
P4510describes a project that usesImageJQ1659584
P433issue7
P407language of work or nameEnglishQ1860
P304page(s)1865-1879.e9
P577publication date2018-08-01
P1433published inCell ReportsQ5058165
P1476titleNeuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration
P478volume24

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cites work (P2860)
Q92451156Differential requirements of tubulin genes in mammalian forebrain development
Q92243130Nasal Placode Development, GnRH Neuronal Migration and Kallmann Syndrome
Q64265139Natural Killer Cells Degenerate Intact Sensory Afferents following Nerve Injury
Q99631302Postnatal Role of the Cytoskeleton in Adult Epileptogenesis
Q93163072Purification of tubulin with controlled post-translational modifications by polymerization-depolymerization cycles
Q89927140The tubulin code and its role in controlling microtubule properties and functions
Q90416862Tubulin mutations in brain development disorders: Why haploinsufficiency does not explain TUBA1A tubulinopathies

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