High-fat diet protects the blood-brain barrier in an Alzheimer's disease mouse model

article published in 2018

High-fat diet protects the blood-brain barrier in an Alzheimer's disease mouse model is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/ACEL.12818
P932PMC publication ID6156545
P698PubMed publication ID30079520

P50authorDavid GuezQ59688296
P2093author name stringItzik Cooper
Yael Mardor
Michal Schnaider Beeri
Alicia Leikin-Frenkel
David Last
Inbal Sharvit-Ginon
Roni Lotan
Chen Shemesh
Rachel Twitto-Greenberg
Shirin Elhaik Goldman
Dana Atrakchi-Baranes
Sigal Liraz Zaltsman
Aviv Shish
Sharone Naor
Shoval Tsach
P2860cites workDiabetes mellitus and risk of Alzheimer disease and decline in cognitive functionQ38422040
Lipids in Amyloid-β Processing, Aggregation, and ToxicityQ38543419
High fat diet exacerbates Alzheimer's disease-related pathology in APPswe/PS1 miceQ42123847
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Reconstituted HDL infusion restores endothelial function in patients with type 2 diabetes mellitusQ43201242
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Blood-brain barrier permeability precedes senile plaque formation in an Alzheimer disease modelQ44743810
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Blood-Brain Barrier Leakage in Patients with Early Alzheimer DiseaseQ47662024
Dietary supplementation of walnuts improves memory deficits and learning skills in transgenic mouse model of Alzheimer's diseaseQ47847027
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Aged Tg2576 mice are impaired on social memory and open field habituation testsQ48317805
Improved reliability of hippocampal atrophy rate measurement in mild cognitive impairment using fluid registrationQ48335273
Learning is improved by a soybean oil diet in ratsQ48343979
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Alzheimer Disease in the US PopulationQ22253055
The clinical use of structural MRI in Alzheimer diseaseQ24609648
Insulin in the brain: its pathophysiological implications for States related with central insulin resistance, type 2 diabetes and Alzheimer's diseaseQ26866392
A high-fat diet and NAD(+) activate Sirt1 to rescue premature aging in cockayne syndromeQ27318209
Neutrophil elastase-mediated degradation of IRS-1 accelerates lung tumor growthQ28270711
Diabetes Mellitus and Blood-Brain Barrier Dysfunction: An OverviewQ28386522
Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disordersQ29615839
Quantitative imaging assessment of blood-brain barrier permeability in humans.Q30587216
The high-fat diet-fed mouse: a model for studying mechanisms and treatment of impaired glucose tolerance and type 2 diabetesQ31131756
Increased food intake leads to obesity and insulin resistance in the tg2576 Alzheimer's disease mouse modelQ33772344
Transgenic mice overexpressing amyloid precursor protein exhibit early metabolic deficits and a pathologically low leptin state associated with hypothalamic dysfunction in arcuate neuropeptide Y neuronsQ33832139
Dietary fats and the risk of incident Alzheimer diseaseQ33964261
Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's diseaseQ34229644
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Vascular basis for brain degeneration: faltering controls and risk factors for dementiaQ34680483
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Momordica charantia (bitter melon) attenuates high-fat diet-associated oxidative stress and neuroinflammationQ35086140
Blood-brain barrier breakdown in the aging human hippocampusQ35151019
Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathyQ35590867
Delayed contrast extravasation MRI: a new paradigm in neuro-oncologyQ35788925
Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive declineQ35858095
Antiinflammatory properties of HDL.Q35919164
Monounsaturated fatty acids prevent the aversive effects of obesity on locomotion, brain activity, and sleep behaviorQ36047630
Protective associations of HDL with blood-brain barrier injury in multiple sclerosis patients.Q36093231
Spatial Cognition in Adult and Aged Mice Exposed to High-Fat DietQ36136974
Hippocampal Insulin Resistance Impairs Spatial Learning and Synaptic PlasticityQ36186276
Studies of the effects of high fat diets on cognitive function in a rat modelQ36283934
Association between fatty acid metabolism in the brain and Alzheimer disease neuropathology and cognitive performance: A nontargeted metabolomic studyQ36316280
HDL antielastase activity prevents smooth muscle cell anoikis, a potential new antiatherogenic propertyQ37326921
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectblood–brain barrierQ221694
AgeingQ50986719
P304page(s)e12818
P577publication date2018-10-01
P1433published inAging CellQ2221073
P1476titleHigh-fat diet protects the blood-brain barrier in an Alzheimer's disease mouse model
P478volume17

Reverse relations

Q96576929High fat diet worsens Alzheimer's disease-related behavioral abnormalities and neuropathology in APP/PS1 mice, but not by synergistically decreasing cerebral blood flowcites workP2860

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