Building C(sp)-rich complexity by combining cycloaddition and C-C cross-coupling reactions

scientific article published in Nature

Building C(sp)-rich complexity by combining cycloaddition and C-C cross-coupling reactions is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1105858689
P356DOI10.1038/S41586-018-0391-9
P932PMC publication ID6126906
P698PubMed publication ID30061620

P50authorIñaki BastidaQ61161353
Shota AsaiQ61161355
P2093author name stringPhil S Baran
Hui Fang
Tian Qin
Tie-Gen Chen
Jason S Chen
Francis G Fang
Mingde Shan
Cheng Bi
David Kossler
Yutong Lin
Hyeong-Wook Choi
Lynn Hawkins
Lisa M Barton
Jet Tsien
P2860cites workMetal-Catalyzed Cross-Coupling Reactions and MoreQ59203408
RECENT SYNTHESES OF EPIBATIDINE. A REVIEWQ63090235
Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensivesQ67948436
Iron-catalyzed Suzuki-Miyaura coupling of alkyl halidesQ84646956
Asymmetric Diels-Alder reactions catalyzed by a triflic acid activated chiral oxazaborolidineQ28213986
A general alkyl-alkyl cross-coupling enabled by redox-active esters and alkylzinc reagentsQ28834226
Big Data from Pharmaceutical Patents: A Computational Analysis of Medicinal Chemists' Bread and ButterQ31065255
Practical Ni-Catalyzed Aryl-Alkyl Cross-Coupling of Secondary Redox-Active Esters.Q34511919
Analysis of Past and Present Synthetic Methodologies on Medicinal Chemistry: Where Have All the New Reactions Gone?Q35842174
Epothilones: a novel class of microtubule-stabilizing drugs for the treatment of cancerQ37236419
The Diels--Alder reaction in total synthesis.Q37596336
Analysis of the structural diversity, substitution patterns, and frequency of nitrogen heterocycles among U.S. FDA approved pharmaceuticalsQ38254225
The EED protein-protein interaction inhibitor A-395 inactivates the PRC2 complexQ38718857
Recent Advances in the Synthesis of Cyclobutanes by Olefin [2 + 2] Photocycloaddition ReactionsQ38790718
Chemical synthesis and biological evaluation of cis- and trans-12,13-cyclopropyl and 12,13-cyclobutyl epothilones and related pyridine side chain analogues.Q40779922
Nickel-Catalyzed Cross-Coupling of Redox-Active Esters with Boronic Acids.Q41828474
Decarboxylative alkenylation.Q42336176
Potent quinoxaline-based inhibitors of PDGF receptor tyrosine kinase activity. Part 1: SAR exploration and effective bioisosteric replacement of a phenyl substituentQ44563638
Decarboxylative Alkynylation.Q48245463
Escape from flatland: increasing saturation as an approach to improving clinical successQ48833163
The Ireland-Claisen rearrangement strategy towards the synthesis of the schizophrenia drug, (+)-asenapine.Q50903078
P433issue7718
P407language of work or nameEnglishQ1860
P921main subjectcycloadditionQ898648
P304page(s)350-354
P577publication date2018-08-01
P1433published inNatureQ180445
P1476titleBuilding C(sp)-rich complexity by combining cycloaddition and C-C cross-coupling reactions
P478volume560

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cites work (P2860)
Q92819447A Radical Approach to Anionic Chemistry: Synthesis of Ketones, Alcohols, and Amines
Q92431678A modular approach to prepare enantioenriched cyclobutanes: synthesis of (+)-rumphellaone A
Q90534595Active template rotaxane synthesis through the Ni-catalyzed cross-coupling of alkylzinc reagents with redox-active esters
Q93072013Enantio- and Diastereoselective Suzuki-Miyaura Coupling with Racemic Bicycles
Q64106564Modular, stereocontrolled C-H/C-C activation of alkyl carboxylic acids
Q90710514Radical Retrosynthesis
Q59083560Reaction combination opens up 3D molecular diversity for drug discovery
Q90609905Readily accessible sp3-rich cyclic hydrazine frameworks exploiting nitrogen fluxionality
Q93203519Solar Photochemistry in Flow

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