Verapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways

Verapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways is …
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scholarly articleQ13442814

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P356DOI10.3389/FENDO.2018.00640
P932PMC publication ID6220071
P698PubMed publication ID30429827

P2093author name stringJing Chen
Ying Zhang
Feng Zhou
Yancheng Xu
Yimeng Hu
P2860cites workEpigallocatechin gallate attenuates fibrosis, oxidative stress, and inflammation in non-alcoholic fatty liver disease rat model through TGF/SMAD, PI3 K/Akt/FoxO1, and NF-kappa B pathways.Q50482649
Protective effect of verapamil on multiple hepatotoxic factors-induced liver fibrosis in ratsQ79559623
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The inflammasomesQ24304087
Reactive oxygen species-induced TXNIP drives fructose-mediated hepatic inflammation and lipid accumulation through NLRP3 inflammasome activationQ28390197
Thioredoxin-interacting protein mediates hepatic lipogenesis and inflammation via PRMT1 and PGC-1α regulation in vitro and in vivoQ28585441
A rapid micropreparation technique for extraction of DNA-binding proteins from limiting numbers of mammalian cellsQ29547557
Thioredoxin-interacting protein links oxidative stress to inflammasome activationQ29614471
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The diagnosis and management of non-alcoholic fatty liver disease: practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology, and the American Gastroenterological AssociationQ29617157
Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammationQ33755829
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Preventing β-cell loss and diabetes with calcium channel blockersQ35857734
NALP-3 inflammasome silencing attenuates ceramide-induced transepithelial permeabilityQ35881730
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Association of pro-inflammatory cytokines, adipokines & oxidative stress with insulin resistance & non-alcoholic fatty liver disease.Q36289689
New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in ratsQ37040345
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Bee's honey attenuates non-alcoholic steatohepatitis-induced hepatic injury through the regulation of thioredoxin-interacting protein-NLRP3 inflammasome pathwayQ38858068
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Thioredoxin-interacting protein mediates ER stress-induced β cell death through initiation of the inflammasomeQ39299566
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Treatment with an Interleukin 1 beta antibody improves glycemic control in diet-induced obesityQ42703006
Resveratrol ameliorates hepatic metaflammation and inhibits NLRP3 inflammasome activationQ42706386
Kupffer cells promote hepatic steatosis via interleukin-1beta-dependent suppression of peroxisome proliferator-activated receptor alpha activityQ43200840
Hepatic progenitor cell inhibition during embryonic period with high dose verapamil; liable joint to the cancer therapy.Q43768435
Liraglutide attenuates lipopolysaccharide-induced acute lung injury in miceQ47371785
Carbachol ameliorates lipopolysaccharide-induced intestinal epithelial tight junction damage by down-regulating NF-κβ and myosin light-chain kinase pathwaysQ48120530
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectverapamilQ410291
P304page(s)640
P577publication date2018-01-01
P1433published inFrontiers in EndocrinologyQ27723680
P1476titleVerapamil Ameliorates Hepatic Metaflammation by Inhibiting Thioredoxin-Interacting Protein/NLRP3 Pathways
P478volume9