human | Q5 |
P856 | official website | https://pure.aber.ac.uk/portal/en/persons/karl-hoffmann(330b658f-27b4-411e-a742-d3995ea9ee96).html |
P496 | ORCID iD | 0000-0002-3932-5502 |
P1153 | Scopus author ID | 7401912877 |
P108 | employer | Aberystwyth University | Q319761 |
P734 | family name | Hoffmann | Q23907787 |
Hoffmann | Q23907787 | ||
Hoffmann | Q23907787 | ||
P735 | given name | Karl | Q15731830 |
Karl | Q15731830 | ||
P106 | occupation | researcher | Q1650915 |
P21 | sex or gender | male | Q6581097 |
Q39063692 | (Epi)genetic Inheritance in Schistosoma mansoni: A Systems Approach |
Q58543612 | An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola hepatica and Schistosoma mansoni |
Q28471672 | Anti-schistosomal intervention targets identified by lifecycle transcriptomic analyses |
Q91984532 | Antischistosomal Properties of Sclareol and Its Heck-Coupled Derivatives: Design, Synthesis, Biological Evaluation, and Untargeted Metabolomics |
Q21263156 | Biomphalaria glabrata transcriptome: cDNA microarray profiling identifies resistant- and susceptible-specific gene expression in haemocytes from snail strains exposed to Schistosoma mansoni |
Q24806615 | Characterization of the Schistosoma transcriptome opens up the world of helminth genomics |
Q122712578 | Chemical modulation of Schistosoma mansoni lysine specific demethylase 1 (SmLSD1) induces wide-scale biological and epigenomic changes |
Q34760480 | Chemotherapy for schistosomiasis in Ugandan fishermen: treatment can cause a rapid increase in interleukin-5 levels in plasma but decreased levels of eosinophilia and worm-specific immunoglobulin E |
Q59171150 | Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni |
Q64123485 | Corrigendum to 'the anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities' [Int. J. Parasitol. Drugs and Drug Resist. 8 (2018) 213-222] |
Q84356134 | Cross-disciplinary approaches for measuring parasitic helminth viability and phenotype |
Q27684629 | Crystal Structure of Schistosoma mansoni Arginase, a Potential Drug Target for the Treatment of Schistosomiasis |
Q34803437 | Cytosine methylation is a conserved epigenetic feature found throughout the phylum Platyhelminthes. |
Q35692564 | Cytosine methylation regulates oviposition in the pathogenic blood fluke Schistosoma mansoni. |
Q96135739 | DC-SIGN mediated internalisation of glycosylated extracellular vesicles from Schistosoma mansoni increases activation of monocyte-derived dendritic cells |
Q36090115 | DISMISS: detection of stranded methylation in MeDIP-Seq data |
Q88484196 | Design, synthesis and anthelmintic activity of 7-keto-sempervirol analogues |
Q33320897 | Developmentally regulated expression, alternative splicing and distinct sub-groupings in members of the Schistosoma mansoni venom allergen-like (SmVAL) gene family. |
Q48546697 | Dioecious Schistosoma mansoni express divergent gene repertoires regulated by pairing. |
Q43771291 | Disease fingerprinting with cDNA microarrays reveals distinct gene expression profiles in lethal type 1 and type 2 cytokine-mediated inflammatory reactions. |
Q27304597 | Drug-induced exposure of Schistosoma mansoni antigens SmCD59a and SmKK7 |
Q34601522 | Eosinophil activity in Schistosoma mansoni infections in vivo and in vitro in relation to plasma cytokine profile pre- and posttreatment with praziquantel |
Q91832307 | Erratum to 'Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma mansoni' [IJP Drugs Drug Resist. 8 (2018) 559-570] |
Q33839269 | Excreted/secreted Schistosoma mansoni venom allergen-like 9 (SmVAL9) modulates host extracellular matrix remodelling gene expression. |
Q38460564 | Gender-associated gene expression in two related strains of Schistosoma japonicum. |
Q36894500 | Glycomics-driven discoveries in schistosome research. |
Q55176668 | Histone methylation changes are required for life cycle progression in the human parasite Schistosoma mansoni. |
Q45243644 | Human IgE response to the Schistosoma haematobium 22.6 kDa antigen. |
Q35684066 | Human IgG1 Responses to Surface Localised Schistosoma mansoni Ly6 Family Members Drop following Praziquantel Treatment |
Q77436972 | IFN-gamma, IL-12, and TNF-alpha are required to maintain reduced liver pathology in mice vaccinated with Schistosoma mansoni eggs and IL-12 |
Q73869153 | IL-10 and the dangers of immune polarization: excessive type 1 and type 2 cytokine responses induce distinct forms of lethal immunopathology in murine schistosomiasis |
Q39594770 | IL-10 is critical for host resistance and survival during gastrointestinal helminth infection. |
Q24802573 | Identification of Schistosoma mansoni gender-associated gene transcripts by cDNA microarray profiling |
Q113240204 | Identification of anti-schistosomal, anthelmintic and anti-parasitic compounds curated and text-mined from the scientific literature |
Q112726430 | Identifying and validating the presence of Guanine-Quadruplexes (G4) within the blood fluke parasite Schistosoma mansoni |
Q74206771 | Immunopathology of schistosomiasis mansoni in mice and men |
Q39070973 | Medicine. Halting harmful helminths. |
Q55456465 | Methyl-CpG-binding (SmMBD2/3) and chromobox (SmCBX) proteins are required for neoblast proliferation and oviposition in the parasitic blood fluke Schistosoma mansoni. |
Q42657284 | Molecular characterization of a 20.8-kDa Schistosoma mansoni antigen. Sequence similarity to tegumental associated antigens and dynein light chains. |
Q48123006 | Molecular characterization of omega-1: a hepatotoxic ribonuclease from Schistosoma mansoni eggs. |
Q39201258 | Neoclerodane Diterpenoids from Reehal Fatima, Teucrium yemense. |
Q82611219 | Parasite genomics and post-genomic activities: 21st century resources for the parasite immunologist |
Q33552532 | Patterns of chemokine expression in models of Schistosoma mansoni inflammation and infection reveal relationships between type 1 and type 2 responses and chemokines in vivo. |
Q112737597 | Plasmacytoid Dendritic Cells Facilitate Th Cell Cytokine Responses throughout Schistosoma mansoni Infection |
Q36215196 | Platyhelminth Venom Allergen-Like (VAL) proteins: revealing structural diversity, class-specific features and biological associations across the phylum. |
Q61816687 | Programmed genome editing of the omega-1 ribonuclease of the blood fluke, |
Q40963179 | Protein and small non-coding RNA-enriched extracellular vesicles are released by the pathogenic blood fluke Schistosoma mansoni |
Q100732696 | Quorum sensing N-Acyl homoserine lactones are a new class of anti-schistosomal |
Q38849208 | Rethinking Schistosomiasis Vaccine Development: Synthetic Vesicles |
Q114054633 | Schistosoma mansoni Larval Extracellular Vesicle protein 1 (SmLEV1) is an immunogenic antigen found in EVs released from pre-acetabular glands of invading cercariae |
Q37373127 | Schistosoma mansoni arginase shares functional similarities with human orthologs but depends upon disulphide bridges for enzymatic activity. |
Q36506127 | Schistosoma mansoni hemozoin modulates alternative activation of macrophages via specific suppression of Retnla expression and secretion. |
Q92343913 | Schistosoma mansoni venom allergen-like proteins: phylogenetic relationships, stage-specific transcription and tissue localization as predictors of immunological cross-reactivity |
Q112637513 | Schistosoma mansoni α-N-acetylgalactosaminidase (SmNAGAL) regulates coordinated parasite movement and egg production |
Q48545599 | Schistosome egg production is dependent upon the activities of two developmentally regulated tyrosinases. |
Q81403739 | Schistosome genomics and beyond: news and views |
Q91782452 | The Anti-mycobacterial Activity of a Diterpenoid-Like Molecule Operates Through Nitrogen and Amino Acid Starvation |
Q33693698 | The Biomphalaria glabrata DNA methylation machinery displays spatial tissue expression, is differentially active in distinct snail populations and is modulated by interactions with Schistosoma mansoni |
Q52591579 | The anti-fecundity effect of 5-azacytidine (5-AzaC) on Schistosoma mansoni is linked to dis-regulated transcription, translation and stem cell activities. |
Q28543997 | The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica |
Q91296049 | The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets |
Q33378459 | Use of genomic DNA as an indirect reference for identifying gender-associated transcripts in morphologically identical, but chromosomally distinct, Schistosoma mansoni cercariae. |
Q33716437 | Whole genome analysis of a schistosomiasis-transmitting freshwater snail. |
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