scholarly article | Q13442814 |
P50 | author | Robert M. Nissen | Q55163376 |
David Salven | Q93366645 | ||
P2093 | author name string | Yang Yu | |
Jingyi Xu | |||
Estibaliz Alvarado | |||
Mina Yousefelahiyeh | |||
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Intragenic deletion in DYRK1A leads to mental retardation and primary microcephaly. | Q51815976 | ||
The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development | Q51961245 | ||
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DYRK1A interacts with histone acetyl transferase p300 and CBP and localizes to enhancers | Q91101430 | ||
The zebrafish dyrk1b gene is important for endoderm formation | Q24646790 | ||
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method | Q25938999 | ||
Case report of novel DYRK1A mutations in 2 individuals with syndromic intellectual disability and a review of the literature | Q26765984 | ||
Wdr68 requires nuclear access for craniofacial development | Q27319944 | ||
The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2 | Q28118783 | ||
Human minibrain homologue (MNBH/DYRK1): characterization, alternative splicing, differential tissue expression, and overexpression in Down syndrome | Q28144031 | ||
A human homologue of Drosophila minibrain (MNB) is expressed in the neuronal regions affected in Down syndrome and maps to the critical region | Q28293718 | ||
Identification of the autophosphorylation sites and characterization of their effects in the protein kinase DYRK1A | Q28362375 | ||
Mirk/dyrk1B is a Rho-induced kinase active in skeletal muscle differentiation | Q28585528 | ||
An organelle-specific protein landscape identifies novel diseases and molecular mechanisms | Q29147481 | ||
WD40 proteins propel cellular networks. | Q30156873 | ||
A human homeotic transformation resulting from mutations in PLCB4 and GNAI3 causes auriculocondylar syndrome | Q30416401 | ||
Dyrk1A haploinsufficiency affects viability and causes developmental delay and abnormal brain morphology in mice | Q30531707 | ||
Mnb/Dyrk1A is transiently expressed and asymmetrically segregated in neural progenitor cells at the transition to neurogenic divisions. | Q30696543 | ||
Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs | Q33217276 | ||
The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation | Q33952905 | ||
Architecture of the human interactome defines protein communities and disease networks | Q34556869 | ||
DYRK1A protein kinase promotes quiescence and senescence through DREAM complex assembly | Q34807677 | ||
A kinase shRNA screen links LATS2 and the pRB tumor suppressor | Q34807689 | ||
Truncation and Activation of Dual Specificity Tyrosine Phosphorylation-regulated Kinase 1A by Calpain I: A MOLECULAR MECHANISM LINKED TO TAU PATHOLOGY IN ALZHEIMER DISEASE. | Q35721878 | ||
Wdr68 Mediates Dorsal and Ventral Patterning Events for Craniofacial Development | Q36202520 | ||
Novel variants in GNAI3 associated with auriculocondylar syndrome strengthen a common dominant negative effect | Q36338193 | ||
Truncation of the Down syndrome candidate gene DYRK1A in two unrelated patients with microcephaly | Q36718950 | ||
Cardiac actin is the major actin gene product in skeletal muscle cell differentiation in vitro | Q36946204 | ||
Interaction of CtBP with adenovirus E1A suppresses immortalization of primary epithelial cells and enhances virus replication during productive infection | Q37066498 | ||
The Drosophila wings apart gene anchors a novel, evolutionarily conserved pathway of neuromuscular development | Q37269839 | ||
Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua | Q37281524 | ||
Mutations in endothelin 1 cause recessive auriculocondylar syndrome and dominant isolated question-mark ears | Q37369042 | ||
Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles | Q37369821 | ||
New Perspectives of Dyrk1A Role in Neurogenesis and Neuropathologic Features of Down Syndrome | Q37500309 | ||
E3 Ligase SCFβTrCP-induced DYRK1A Protein Degradation Is Essential for Cell Cycle Progression in HEK293 Cells | Q37507511 | ||
A multi-ethnic genome-wide association study identifies novel loci for non-syndromic cleft lip with or without cleft palate on 2p24.2, 17q23 and 19q13. | Q37530244 | ||
Activation, regulation, and inhibition of DYRK1A. | Q37815234 | ||
DYRK1A: a potential drug target for multiple Down syndrome neuropathologies | Q38154969 | ||
Prenatal treatment of Down syndrome: a reality? | Q38191420 | ||
Human DNA Ligase I Interacts with and Is Targeted for Degradation by the DCAF7 Specificity Factor of the Cul4-DDB1 Ubiquitin Ligase Complex | Q38749225 | ||
DYRK1A: the double-edged kinase as a protagonist in cell growth and tumorigenesis | Q38866748 | ||
Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase. | Q38916532 | ||
Understanding the Multifaceted Role of Human Down Syndrome Kinase DYRK1A. | Q38938802 | ||
Influence of prenatal EGCG treatment and Dyrk1a dosage reduction on craniofacial features associated with Down syndrome | Q38973876 | ||
Dissection of the C-Terminal Region of E1A Redefines the Roles of CtBP and Other Cellular Targets in Oncogenic Transformation | Q39124298 | ||
DYRK1B mutations associated with metabolic syndrome impair the chaperone-dependent maturation of the kinase domain | Q41124666 | ||
Chloroquine inhibits lysosomal enzyme pinocytosis and enhances lysosomal enzyme secretion by impairing receptor recycling | Q41337499 | ||
Adenovirus type 5 E1A and E6 proteins of low-risk cutaneous beta-human papillomaviruses suppress cell transformation through interaction with FOXK1/K2 transcription factors | Q41859522 | ||
Inhibition of DYRK1A disrupts neural lineage specification in human pluripotent stem cells | Q41918473 | ||
Autophagy Blockade Sensitizes Prostate Cancer Cells towards Src Family Kinase Inhibitors | Q41935042 | ||
DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome | Q42033560 | ||
Functional Similarity between E6 Proteins of Cutaneous Human Papillomaviruses and the Adenovirus E1A Tumor-Restraining Module | Q42214281 | ||
The molecular chaperone TRiC/CCT binds to the Trp-Asp 40 (WD40) repeat protein WDR68 and promotes its folding, protein kinase DYRK1A binding, and nuclear accumulation | Q42550882 | ||
Cytoplasmic activation of human nuclear genes in stable heterocaryons | Q42799501 | ||
Integrative genomics identifies the corepressor SMRT as a gatekeeper of adipogenesis through the transcription factors C/EBPβ and KAISO. | Q42835465 | ||
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation | Q43268600 | ||
DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation | Q43655626 | ||
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome. | Q43736456 | ||
Inhibition of the chymotrypsin-like activity of the pituitary multicatalytic proteinase complex | Q43947832 | ||
Expression patterns and subcellular localization of the Down syndrome candidate protein MNB/DYRK1A suggest a role in late neuronal differentiation. | Q44482754 | ||
minibrain: a new protein kinase family involved in postembryonic neurogenesis in Drosophila | Q47070222 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P4510 | describes a project that uses | ImageJ | Q1659584 |
P433 | issue | 11 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | e0207779 | |
P577 | publication date | 2018-01-01 | |
P1433 | published in | PLOS One | Q564954 |
P1476 | title | DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B | |
P478 | volume | 13 |
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