scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.BBAMCR.2011.06.023 |
P953 | full work available at URL | https://api.elsevier.com/content/article/PII:S0167488911001893?httpAccept=text/plain |
https://api.elsevier.com/content/article/PII:S0167488911001893?httpAccept=text/xml | ||
https://repository.kulib.kyoto-u.ac.jp/dspace/bitstream/2433/148020/1/j.bbamcr.2011.06.023.pdf | ||
P698 | PubMed publication ID | 21777625 |
P5875 | ResearchGate publication ID | 51510127 |
P2093 | author name string | Eisuke Nishida | |
Yoshihiko Miyata | |||
P2860 | cites work | A zebrafish screen for craniofacial mutants identifies wdr68 as a highly conserved gene required for endothelin-1 expression | Q21284144 |
Molecular cloning and characterization of a novel member of the MAP kinase superfamily | Q22010433 | ||
Phosphorylation of Ser640 in Muscle Glycogen Synthase by DYRK Family Protein Kinases | Q24298852 | ||
A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1 | Q24301361 | ||
The WD40-repeat protein Han11 functions as a scaffold protein to control HIPK2 and MEKK1 kinase functions | Q24302518 | ||
A genome-wide Drosophila RNAi screen identifies DYRK-family kinases as regulators of NFAT | Q24306261 | ||
The an11 locus controlling flower pigmentation in petunia encodes a novel WD-repeat protein conserved in yeast, plants, and animals | Q24311764 | ||
Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins | Q37404795 | ||
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine | Q39915098 | ||
DYRK1A-mediated hyperphosphorylation of Tau. A functional link between Down syndrome and Alzheimer disease | Q40074162 | ||
Dyrk1A overexpression in immortalized hippocampal cells produces the neuropathological features of Down syndrome | Q40089393 | ||
The survival kinase Mirk/Dyrk1B is a downstream effector of oncogenic K-ras in pancreatic cancer | Q40099149 | ||
CK2 controls multiple protein kinases by phosphorylating a kinase-targeting molecular chaperone, Cdc37. | Q40763457 | ||
DYRK1B-dependent autocrine-to-paracrine shift of Hedgehog signaling by mutant RAS. | Q42826326 | ||
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation | Q43268600 | ||
Specific association of a set of molecular chaperones including HSP90 and Cdc37 with MOK, a member of the mitogen-activated protein kinase superfamily | Q43559891 | ||
Neurodevelopmental delay, motor abnormalities and cognitive deficits in transgenic mice overexpressing Dyrk1A (minibrain), a murine model of Down's syndrome. | Q43736456 | ||
The protein kinase DYRK1A regulates caspase-9-mediated apoptosis during retina development | Q43971025 | ||
DYRK1A accumulates in splicing speckles through a novel targeting signal and induces speckle disassembly | Q44473703 | ||
Motor phenotypic alterations in TgDyrk1a transgenic mice implicate DYRK1A in Down syndrome motor dysfunction | Q47232491 | ||
DYRK1A BAC transgenic mice show altered synaptic plasticity with learning and memory defects | Q48664609 | ||
The TRANSPARENT TESTA GLABRA1 locus, which regulates trichome differentiation and anthocyanin biosynthesis in Arabidopsis, encodes a WD40 repeat protein | Q52175870 | ||
Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases | Q24316021 | ||
Mirk/Dyrk1B mediates survival during the differentiation of C2C12 myoblasts | Q24532054 | ||
The zebrafish dyrk1b gene is important for endoderm formation | Q24646790 | ||
Phosphorylation of the immunosuppressant FK506-binding protein FKBP52 by casein kinase II: Regulation of HSP90-binding activity of FKBP52 | Q24647502 | ||
Structure of a Fbw7-Skp1-cyclin E complex: multisite-phosphorylated substrate recognition by SCF ubiquitin ligases | Q27644446 | ||
Structure of a signal transduction regulator, RACK1, from Arabidopsis thaliana | Q27651721 | ||
Direct Link between RACK1 Function and Localization at the Ribosome In Vivo | Q27653299 | ||
An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase | Q27662837 | ||
The structure of the G protein heterotrimer Gi alpha 1 beta 1 gamma 2 | Q27732195 | ||
Crystal structure of a G-protein beta gamma dimer at 2.1A resolution | Q27732270 | ||
Cloning and characterization of DYRK1B, a novel member of the DYRK family of protein kinases | Q28118261 | ||
The WD repeat: a common architecture for diverse functions | Q28143827 | ||
Regulation of Gli1 transcriptional activity in the nucleus by Dyrk1 | Q28215795 | ||
WD-repeat proteins: structure characteristics, biological function, and their involvement in human diseases | Q28216786 | ||
The MNB/DYRK1A protein kinase: neurobiological functions and Down syndrome implications | Q28255027 | ||
The MNB/DYRK1A protein kinase: genetic and biochemical properties | Q28255038 | ||
HAN11 binds mDia1 and controls GLI1 transcriptional activity | Q28255678 | ||
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis | Q28292299 | ||
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase | Q28302692 | ||
DYRK1A and glycogen synthase kinase 3beta, a dual-kinase mechanism directing proteasomal degradation of CRY2 for circadian timekeeping | Q28512443 | ||
CK2 binds, phosphorylates, and regulates its pivotal substrate Cdc37, an Hsp90-cochaperone | Q28581892 | ||
Dyrk, a dual specificity protein kinase with unique structural features whose activity is dependent on tyrosine residues between subdomains VII and VIII | Q28583955 | ||
Targeting Dyrk1A with AAVshRNA attenuates motor alterations in TgDyrk1A, a mouse model of Down syndrome. | Q30490193 | ||
Activation-loop autophosphorylation is mediated by a novel transitional intermediate form of DYRKs | Q33217276 | ||
Distantly related cousins of MAP kinase: biochemical properties and possible physiological functions | Q33796123 | ||
The crystal structure of murine coronin-1: a regulator of actin cytoskeletal dynamics in lymphocytes | Q34483597 | ||
NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. | Q34504363 | ||
Mirk/Dyrk1B: a multifunctional dual-specificity kinase involved in growth arrest, differentiation, and cell survival | Q34548054 | ||
The WD-40 repeat | Q36379533 | ||
Overexpression of Dyrk1A contributes to neurofibrillary degeneration in Down syndrome | Q36841753 | ||
Mirk/Dyrk1B, a novel therapeutic target, mediates cell survival in non-small cell lung cancer cells | Q37339695 | ||
Dyrk1A overexpression inhibits proliferation and induces premature neuronal differentiation of neural progenitor cells | Q37347577 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 1728-1739 | |
P577 | publication date | 2011-07-13 | |
P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
P1476 | title | DYRK1A binds to an evolutionarily conserved WD40-repeat protein WDR68 and induces its nuclear translocation | |
P478 | volume | 1813 |
Q64099259 | A complex between DYRK1A and DCAF7 phosphorylates the C-terminal domain of RNA polymerase II to promote myogenesis |
Q89723136 | An isothermal shift assay for proteome scale drug-target identification |
Q39177661 | Analysis of adult cerebral cortex and hippocampus transcriptomes reveals unique molecular changes in the Ts1Cje mouse model of down syndrome |
Q60049142 | DCAF7/WDR68 is required for normal levels of DYRK1A and DYRK1B |
Q42033560 | DYRK1A regulates Hap1-Dcaf7/WDR68 binding with implication for delayed growth in Down syndrome |
Q64229393 | DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169 |
Q26745413 | DYRK1A, a Dosage-Sensitive Gene Involved in Neurodevelopmental Disorders, Is a Target for Drug Development in Down Syndrome |
Q28541616 | Design and synthesis of a library of lead-like 2,4-bisheterocyclic substituted thiophenes as selective Dyrk/Clk inhibitors |
Q38037304 | Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control |
Q55260854 | Hacking the Cell: Network Intrusion and Exploitation by Adenovirus E1A. |
Q36130066 | MiR-1246: a new link of the p53 family with cancer and Down syndrome |
Q48238914 | Plant dual-specificity tyrosine phosphorylation-regulated kinase optimizes light-regulated growth and development in Arabidopsis. |
Q36100140 | Selective autophagic receptor p62 regulates the abundance of transcriptional coregulator ARIP4 during nutrient starvation. |
Q89621131 | TNFα-Signaling Modulates the Kinase Activity of Human Effector Treg and Regulates IL-17A Expression |
Q46388847 | The Adenovirus E1A C Terminus Suppresses a Delayed Antiviral Response and Modulates RAS Signaling |
Q33952905 | The Down syndrome-related protein kinase DYRK1A phosphorylates p27(Kip1) and Cyclin D1 and induces cell cycle exit and neuronal differentiation |
Q35578920 | The Tumor Suppressor NKX3.1 Is Targeted for Degradation by DYRK1B Kinase |
Q28118783 | The adaptor protein DCAF7 mediates the interaction of the adenovirus E1A oncoprotein with the protein kinases DYRK1A and HIPK2 |
Q53089292 | The landscape of somatic mutations in Down syndrome-related myeloid disorders |
Q42550882 | The molecular chaperone TRiC/CCT binds to the Trp-Asp 40 (WD40) repeat protein WDR68 and promotes its folding, protein kinase DYRK1A binding, and nuclear accumulation |
Q64091236 | The nuclear interactome of DYRK1A reveals a functional role in DNA damage repair |
Q36202520 | Wdr68 Mediates Dorsal and Ventral Patterning Events for Craniofacial Development |
Q27319944 | Wdr68 requires nuclear access for craniofacial development |
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