Cytoprotective effects of molsidomine against methotrexate-induced hepatotoxicity: an experimental rat study

scientific article published on 20 December 2018

Cytoprotective effects of molsidomine against methotrexate-induced hepatotoxicity: an experimental rat study is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/DDDT.S181550
P932PMC publication ID6304250
P698PubMed publication ID30587924

P50authorHakan ParlakpinarQ74762349
P2093author name stringEmine Turkmen Samdanci
Ayse Nur Akatli
Esra Pamukcu
Kevser Tanbek
Mustafa Huz
Onural Ozhan
P2860cites workCyclic GMP as the mediator of molsidomine-induced vasodilatation.Q50910391
Beneficial effects of montelukast against methotrexate-induced liver toxicity: a biochemical and histological study.Q51341263
Assessment of liver fibrosis by transient elastography in rheumatoid arthritis patients treated with methotrexate.Q53470712
Protective effect of infliximab on methotrexate-induced liver injury in rats: unexpected drug interaction.Q53540748
Comparative short-term effect of once-daily molsidomine on chronic angina in general practitioners' versus cardiologists' coronary patient populations.Q54488507
A simple method for clinical assay of superoxide dismutaseQ68286262
N-acetylcysteine ameliorates methotrexate-induced oxidative liver damage in ratsQ79977098
Selenium concentration and glutathione peroxidase (GSH-Px) activity in serum of cows at different stages of lactationQ82536620
Protective Effects of Molsidomine Against Cisplatin-Induced NephrotoxicityQ86492167
Myeloperoxidase: a new biomarker of inflammation in ischemic heart disease and acute coronary syndromesQ21342799
Tissue sulfhydryl groupsQ26778486
Protective effect of beta-glucan against oxidative organ injury in a rat model of sepsisQ33217018
Glutathione homeostasis in response to exercise training and nutritional supplementsQ33712159
Rare incidence of methotrexate-specific lesions in liver biopsy of patients with arthritis and elevated liver enzymesQ34153004
Superoxide dismutases: role in redox signaling, vascular function, and diseasesQ34176532
Acute renal failure: is nitric oxide the bad guy?Q35062289
Liver injury in long-term methotrexate treatment in psoriasis is relatively infrequentQ36570815
Biochemically and histopathologically comparative review of thiamine's and thiamine pyrophosphate's oxidative stress effects generated with methotrexate in rat liver.Q38063810
Hepatotoxicity caused by methotrexate therapy in children with inflammatory bowel disease: a systematic review and meta-analysisQ38166551
Relaxation of bovine coronary artery and activation of coronary arterial guanylate cyclase by nitric oxide, nitroprusside and a carcinogenic nitrosoamineQ39269807
Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidaseQ39513011
Methotrexate in psoriasis: revised guidelinesQ39514650
Apoptosis of hepatic stellate cells mediated by specific protein nitration.Q39635047
Preventive and early therapeutic effects of β-glucan on the bleomycin-induced lung fibrosis in ratsQ40946514
Risk of liver disease in methotrexate treated patientsQ42363647
Resveratrol ameliorates methotrexate-induced hepatotoxicity in rats via inhibition of lipid peroxidationQ42712848
Assessment of liver fibrosis with transient elastography and FibroTest in patients treated with methotrexate for chronic inflammatory diseases: a case-control studyQ42923248
Protective effect of beta-carotene on methotrexate-induced oxidative liver damage.Q43071513
Methotrexate-induced apoptosis in hepatocytes after partial hepatectomyQ43925485
Melatonin prevents methotrexate-induced hepatorenal oxidative injury in rats.Q44380579
Determination of malonaldehyde precursor in tissues by thiobarbituric acid testQ44764466
Effects of molsidomine and lexipafant in hepatic ischaemia--reperfusion injuryQ44881846
Lung injury after aortic occlusion-reperfusion in rats: the role of gadolinium chlorideQ45009318
Effect of molsidomine and L-arginine in cyclosporine nephrotoxicity: role of nitric oxideQ45233576
Reversal of iron-induced nephrotoxicity in rats by molsidomine, a nitric oxide donorQ46951571
Molsidomine prevents cisplatin-induced hepatotoxicity.Q46983624
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjecthepatotoxicityQ1349821
drug discoveryQ1418791
P304page(s)13-21
P577publication date2018-12-20
P1433published inDrug Design, Development and TherapyQ2566724
P1476titleCytoprotective effects of molsidomine against methotrexate-induced hepatotoxicity: an experimental rat study
P478volume13

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