| scholarly article | Q13442814 |
| P356 | DOI | 10.1002/EJI.200737293 |
| P698 | PubMed publication ID | 17853409 |
| P50 | author | Teresa Lambe | Q43124022 |
| P2093 | author name string | Simon Milling | |
| Richard J Cornall | |||
| Tanya L Crockford | |||
| Tiphaine Bouriez-Jones | |||
| Karlee L Silver | |||
| P2860 | cites work | Selective expression of a protein-tyrosine kinase, p56lyn, in hematopoietic cells and association with production of human T-cell lymphotropic virus type I | Q24608015 |
| Origins and functions of B-1 cells with notes on the role of CD5 | Q28203450 | ||
| Polygenic autoimmune traits: Lyn, CD22, and SHP-1 are limiting elements of a biochemical pathway regulating BCR signaling and selection | Q28270723 | ||
| Defective negative regulation of antigen receptor signaling in Lyn-deficient B lymphocytes | Q28271869 | ||
| Regulation of B-1 cell activation and its autoantibody production by Lyn kinase-regulated signallings | Q28509762 | ||
| Hyperresponsive B cells in CD22-deficient mice | Q28510573 | ||
| Characterization of the B lymphocyte populations in Lyn-deficient mice and the role of Lyn in signal initiation and down-regulation | Q28584704 | ||
| Lyn-deficient mice develop severe, persistent asthma: Lyn is a critical negative regulator of Th2 immunity | Q28585093 | ||
| Altered antigen receptor signaling and impaired Fas-mediated apoptosis of B cells in Lyn-deficient mice | Q28589721 | ||
| The Lyn tyrosine kinase differentially regulates dendritic cell generation and maturation | Q28592165 | ||
| FcgammaRIV: a novel FcR with distinct IgG subclass specificity | Q28594064 | ||
| Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors | Q29615065 | ||
| Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function | Q29617462 | ||
| A stop codon polymorphism of Toll-like receptor 5 is associated with resistance to systemic lupus erythematosus | Q33906588 | ||
| Dendritic-cell function in Toll-like receptor- and MyD88-knockout mice | Q34207563 | ||
| Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus. | Q34566135 | ||
| Toll-like receptors in systemic autoimmune disease | Q34576448 | ||
| A Tlr7 translocation accelerates systemic autoimmunity in murine lupus | Q34773105 | ||
| Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases | Q34792083 | ||
| TLR9/MyD88 signaling is required for class switching to pathogenic IgG2a and 2b autoantibodies in SLE. | Q36228411 | ||
| Autoantibodies make a U-turn: the toll hypothesis for autoantibody specificity | Q36332185 | ||
| Induction of a cationic shift in IgG anti-DNA autoantibodies. Role of T helper cells with classical and novel phenotypes in three murine models of lupus nephritis | Q36352584 | ||
| Bruton's tyrosine kinase links the B cell receptor to nuclear factor kappaB activation | Q36368467 | ||
| Bruton's tyrosine kinase is required for activation of IkappaB kinase and nuclear factor kappaB in response to B cell receptor engagement | Q36368492 | ||
| Toll-like receptor 9 controls anti-DNA autoantibody production in murine lupus | Q36403146 | ||
| RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement. | Q36403678 | ||
| Immune stimulation mediated by autoantigen binding sites within small nuclear RNAs involves Toll-like receptors 7 and 8. | Q36403992 | ||
| A critical role of Lyn and Fyn for B cell responses to CD38 ligation and interleukin 5 | Q36585953 | ||
| Interleukin 6: from bench to bedside | Q36639873 | ||
| Generation of plasmacytomas with the chromosomal translocation t(12;15) in interleukin 6 transgenic mice. | Q36765782 | ||
| Autoreactive B cell responses to RNA-related antigens due to TLR7 gene duplication | Q38313174 | ||
| Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells | Q38336314 | ||
| Activation of toll-like receptor-9 induces progression of renal disease in MRL-Fas(lpr) mice | Q38345765 | ||
| Toll-like receptor 9 binds single-stranded CpG-DNA in a sequence- and pH-dependent manner. | Q40526242 | ||
| Bruton's tyrosine kinase is a Toll/interleukin-1 receptor domain-binding protein that participates in nuclear factor kappaB activation by Toll-like receptor 4. | Q40651159 | ||
| Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice. | Q41423746 | ||
| In vivo CpG DNA/toll-like receptor 9 interaction induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis | Q43004178 | ||
| Reduced dosage of Bruton's tyrosine kinase uncouples B cell hyperresponsiveness from autoimmunity in lyn-/- mice | Q44111852 | ||
| CD19 regulates innate immunity by the toll-like receptor RP105 signaling in B lymphocytes | Q44417166 | ||
| Protein tyrosine phosphatase 1C negatively regulates antigen receptor signaling in B lymphocytes and determines thresholds for negative selection. | Q46463458 | ||
| Toll-like receptor 9 signaling protects against murine lupus | Q46872996 | ||
| CpG DNA redirects class-switching towards "Th1-like" Ig isotype production via TLR9 and MyD88. | Q47681916 | ||
| CD22 is both a positive and negative regulator of B lymphocyte antigen receptor signal transduction: altered signaling in CD22-deficient mice. | Q52198671 | ||
| Suppressive oligodeoxynucleotides delay the onset of glomerulonephritis and prolong survival in lupus-prone NZB × NZW mice | Q56897860 | ||
| Control of B-cell responses by Toll-like receptors | Q59066168 | ||
| Impaired proliferation of peripheral B cells and indication of autoimmune disease in lyn-deficient mice | Q71800467 | ||
| Multiple defects in the immune system of Lyn-deficient mice, culminating in autoimmune disease | Q71806455 | ||
| Defective IL-5-receptor-mediated signaling in B cells of X-linked immunodeficient mice | Q72159421 | ||
| The role of cpg sequences in the induction of anti-DNA antibodies | Q74243213 | ||
| Systemic lupus erythematosus: an autoimmune disease of B cell hyperactivity | Q74433998 | ||
| Unresponsiveness of MyD88-deficient mice to endotoxin | Q78093558 | ||
| Spontaneous class switching and B cell hyperactivity increase autoimmunity against intracellular self antigen in Lyn-deficient mice | Q79236399 | ||
| Effects of TREM-1 activation in human neutrophils: activation of signaling pathways, recruitment into lipid rafts and association with TLR4 | Q79349810 | ||
| Activation of autoreactive B cells by CpG dsDNA | Q79361609 | ||
| IL-6 produced by dendritic cells from lupus-prone mice inhibits CD4+CD25+ T cell regulatory functions | Q79445141 | ||
| Immunology. Discriminating microbe from self suffers a double toll | Q79734063 | ||
| T-cell control of IL-12p75 production | Q79984798 | ||
| Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus | Q81557781 | ||
| TLR4, TLR9 and MyD88 are not required for the positive selection of autoreactive B cells into the primary repertoire | Q83352530 | ||
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | autoimmune disease | Q8084905 |
| P304 | page(s) | 2734-2743 | |
| P577 | publication date | 2007-10-01 | |
| P1433 | published in | European Journal of Immunology | Q5412727 |
| P1476 | title | MyD88-dependent autoimmune disease in Lyn-deficient mice | |
| P478 | volume | 37 |
| Q42290162 | A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens |
| Q33849420 | A balance between B cell receptor and inhibitory receptor signaling controls plasma cell differentiation by maintaining optimal Ets1 levels |
| Q42725543 | Activated basophils give lupus a booster shot |
| Q36080732 | Altered BCR and TLR signals promote enhanced positive selection of autoreactive transitional B cells in Wiskott-Aldrich syndrome |
| Q34364711 | B cell-intrinsic TLR7 signaling is essential for the development of spontaneous germinal centers. |
| Q37509056 | B cell-specific loss of Lyn kinase leads to autoimmunity |
| Q37264281 | Cd47-Sirpα interaction and IL-10 constrain inflammation-induced macrophage phagocytosis of healthy self-cells |
| Q26829061 | Contribution of Toll-like receptor signaling to germinal center antibody responses |
| Q36453064 | Elevated BCR signaling and decreased survival of Lyn-deficient transitional and follicular B cells |
| Q89060748 | Fas ligand promotes an inducible TLR-dependent model of cutaneous lupus-like inflammation |
| Q37107525 | Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways. |
| Q42956804 | IL-6 increases B-cell IgG production in a feed-forward proinflammatory mechanism to skew hematopoiesis and elevate myeloid production |
| Q36910636 | Integrin CD11b attenuates colitis by strengthening Src-Akt pathway to polarize anti-inflammatory IL-10 expression |
| Q28506491 | Integrin CD11b negatively regulates TLR-triggered inflammatory responses by activating Syk and promoting degradation of MyD88 and TRIF via Cbl-b |
| Q37381383 | LYN- and AIRE-mediated tolerance checkpoint defects synergize to trigger organ-specific autoimmunity |
| Q52726230 | Lyn, Lupus, and (B) Lymphocytes, a Lesson on the Critical Balance of Kinase Signaling in Immunity. |
| Q35068019 | Mediators of Tyrosine Phosphorylation in Innate Immunity: From Host Defense to Inflammation onto Oncogenesis |
| Q37734746 | Microbial TLR Agonists and Humoral Immunopathogenesis in HIV Disease |
| Q33882051 | Molecular control of steady-state dendritic cell maturation and immune homeostasis |
| Q37416257 | Multiple roles of Lyn kinase in myeloid cell signaling and function |
| Q37526582 | Mycobacterium tuberculosis, autoimmunity, and vitamin D. |
| Q34044394 | Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice |
| Q33911256 | Requirement for MyD88 signaling in B cells and dendritic cells for germinal center anti-nuclear antibody production in Lyn-deficient mice |
| Q37801738 | Role for toll-like receptors in autoimmune disease: The example of systemic lupus erythematosus |
| Q35813976 | Roles of B Cell-Intrinsic TLR Signals in Systemic Lupus Erythematosus. |
| Q34671298 | Separate checkpoints regulate splenic plasma cell accumulation and IgG autoantibody production in Lyn-deficient mice |
| Q40343247 | Spontaneous germinal centers and autoimmunity |
| Q92511099 | Systemic silencing of PHD2 causes reversible immune regulatory dysfunction |
| Q24603972 | Themis is a member of a new metazoan gene family and is required for the completion of thymocyte positive selection |
| Q37838577 | Toll-like receptor driven B cell activation in the induction of systemic autoimmunity |
| Q57039639 | [EXPRESS] CD11b activated Src signal attenuates neuroinflammatory pain by orchestrating inflammatory and anti-inflammatory cytokines in microglia |
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