Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas

scientific article published on 30 August 2010

Analysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1136/BJO.2009.174417
P698PubMed publication ID20805136

P50authorPaula SoaresQ37840702
João VinagreQ38328016
José Manuel LopesQ42913152
Helena PópuloQ47823801
P2093author name stringP. Soares
J. M. Lopes
H. Populo
J. Vinagre
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)715-719
P577publication date2010-08-30
P1433published inBritish Journal of OphthalmologyQ13443571
P1476titleAnalysis of GNAQ mutations, proliferation and MAPK pathway activation in uveal melanomas
P478volume95

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cites work (P2860)
Q30490586Activation of PKCα and PI3K Kinases in Hypertrophic and Nodular Port Wine Stain Lesions
Q36100681Detection of GNAQ mutations and reduction of cell viability in uveal melanoma cells with functionalized gold nanoparticles.
Q39145837Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma
Q39120274Frequency of TERT promoter mutations in human cancers
Q47223959Frequent and Yet Unreported GNAQ and GNA11 Mutations are Found in Uveal Melanomas.
Q37058301GNAQ and BRAF mutations show differential activation of the mTOR pathway in human transformed cells.
Q64949664Heterogeneity in Mitogen-Activated Protein Kinase (MAPK) Pathway Activation in Uveal Melanoma With Somatic GNAQ and GNA11 Mutations.
Q39440294LARG links histamine-H1-receptor-activated Gq to Rho-GTPase-dependent signaling pathways
Q37457622Minimal contribution of ERK1/2-MAPK signalling towards the maintenance of oncogenic GNAQQ209P-driven uveal melanomas in zebrafish
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Q37093540P53 mutations in advanced cancers: clinical characteristics, outcomes, and correlation between progression-free survival and bevacizumab-containing therapy
Q33853615SDHD promoter mutations are rare events in cutaneous melanomas but SDHD protein expression is downregulated in advanced cutaneous melanoma
Q34602677Sustained activation of c-Jun N-terminal and extracellular signal-regulated kinases in port-wine stain blood vessels
Q64916607The Pathogenesis of Port Wine Stain and Sturge Weber Syndrome: Complex Interactions between Genetic Alterations and Aberrant MAPK and PI3K Activation.
Q37742632The biology of uveal melanoma
Q34130528The protein kinase C inhibitor enzastaurin exhibits antitumor activity against uveal melanoma
Q33872396Uveal melanoma cell growth is inhibited by aminoimidazole carboxamide ribonucleotide (AICAR) partially through activation of AMP-dependent kinase
Q92861881miR-142-3p suppresses uveal melanoma by targeting CDC25C, TGFβR1, GNAQ, WASL, and RAC1

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