| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Eduardo Melani Rocha | Q44439973 |
| Thiago Mattar Cunha | Q42317688 | ||
| P2093 | author name string | Valéria Valim | |
| Leidiane Adriano | |||
| Marina Zilio Fantucci | |||
| Paulo Louzada-Junior | |||
| Fabíola Reis de Oliveira | |||
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| Comparison of diagnostic tests in distinct well-defined conditions related to dry eye disease | Q33645315 | ||
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| Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons | Q33884499 | ||
| 'ASIA' - autoimmune/inflammatory syndrome induced by adjuvants | Q34023471 | ||
| Hepatitis Delta Virus Detected in Salivary Glands of Sjögren's Syndrome Patients and Recapitulates a Sjögren's Syndrome-Like Phenotype in Vivo | Q34047019 | ||
| Silent glutamatergic synapses and long-term facilitation in spinal dorsal horn neurons | Q34094011 | ||
| EULAR Sjogren's syndrome disease activity index: development of a consensus systemic disease activity index for primary Sjogren's syndrome | Q34117422 | ||
| Modular transcriptional repertoire analyses of adults with systemic lupus erythematosus reveal distinct type I and type II interferon signatures | Q34149941 | ||
| Antibodies and the Brain: Lessons from Lupus | Q34201906 | ||
| Acetylcholine-synthesizing T cells relay neural signals in a vagus nerve circuit | Q34216728 | ||
| Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa | Q34275205 | ||
| Neurotoxic lupus autoantibodies alter brain function through two distinct mechanisms. | Q34276891 | ||
| Neuroendocrine-immune system interactions and autoimmunity | Q34300053 | ||
| Insulin and glucagon as a new regulator system for tryptophan oxygenase activity demonstrated in primary cultured rat hepatocytes | Q42450854 | ||
| The activation of serotonin receptors prevents glutamate-induced neurotoxicity and NMDA-stimulated cGMP accumulation in primary cortical cell cultures | Q42527643 | ||
| Sources of the neurotoxin quinolinic acid in the brain of HIV-1-infected patients and retrovirus-infected macaques | Q42541200 | ||
| Quinolinic acid in tumors, hemorrhage and bacterial infections of the central nervous system in children | Q42557191 | ||
| The level of BLyS (BAFF) correlates with the titre of autoantibodies in human Sjögren's syndrome | Q43050637 | ||
| Species and cell types difference in tryptophan metabolism | Q43066367 | ||
| Properties and function of indoleamine 2,3-dioxygenase | Q43407543 | ||
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| NMDA antagonists interact with 5-HT-stimulated phosphatidylinositol metabolism and impair passive avoidance retention in the rat. | Q43514296 | ||
| Aspirin and dry eye? | Q43610378 | ||
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| Increased depressive ratings in patients with hepatitis C receiving interferon-alpha-based immunotherapy are related to interferon-alpha-induced changes in the serotonergic system | Q43859445 | ||
| N(G)-nitro-L-arginine and its methyl ester inhibit brain synthesis of kynurenic acid possibly via nitric oxide-independent mechanism | Q43976971 | ||
| Modulation of blood-brain barrier dysfunction and neurological deficits during acute experimental allergic encephalomyelitis by the N-methyl-D-aspartate receptor antagonist memantine | Q44028856 | ||
| Association between decreased serum tryptophan concentrations and depressive symptoms in cancer patients undergoing cytokine therapy. | Q44040242 | ||
| Unaltered pain-related behavior in mice lacking NMDA receptor GluRepsilon 1 subunit | Q44454428 | ||
| Topical and systemic medications for the treatment of primary Sjögren's syndrome. | Q44498935 | ||
| L-cysteine sulphinate, endogenous sulphur-containing amino acid, inhibits rat brain kynurenic acid production via selective interference with kynurenine aminotransferase II. | Q44506316 | ||
| Hippocampal nerve growth factor potentiated by 17β-estradiol and involved in allodynia of inflamed TMJ in rat. | Q44643935 | ||
| Cerebral cortex and lung indoleamine-2,3-dioxygenase activity is increased in type-D retrovirus infected macaques | Q44655679 | ||
| Are women with Sjögren's syndrome androgen-deficient? | Q44694437 | ||
| BLyS upregulation in Sjogren's syndrome associated with lymphoproliferative disorders, higher ESSDAI score and B-cell clonal expansion in the salivary glands. | Q44700638 | ||
| Diclofenac increases the accumulation of kynurenate following tryptophan pretreatment in the rat: a possible factor contributing to its antihyperalgesic effect | Q44808701 | ||
| A comparison of the hormone levels in patients with Sjogren's syndrome and healthy controls | Q44903574 | ||
| Quinolinic acid in the pathogenesis of Alzheimer's disease. | Q44943845 | ||
| The lack of association between signs and symptoms in patients with dry eye disease | Q45122466 | ||
| Aspirin prevents diabetic oxidative changes in rat lacrimal gland structure and function | Q46134751 | ||
| Association of interferon-gamma +874(T/A) single nucleotide polymorphism with the rate of tryptophan catabolism in healthy individuals | Q46457375 | ||
| Indolamine 2,3-dioxygenase is expressed in the CNS and down-regulates autoimmune inflammation | Q46531302 | ||
| Mechanisms dependent on tryptophan catabolism regulate immune responses in primary Sjögren's syndrome | Q46716296 | ||
| An overview of pathways encoding nociception | Q46868460 | ||
| Tryptophan depletion causes a rapid lowering of mood in normal males | Q47357035 | ||
| Estrogen Modulates Corneal Nociception and Maintains Corneal Homeostasis in Rat Eye. | Q47430954 | ||
| Sicca symptoms are associated with similar fatigue, anxiety, depression, and quality-of-life impairments in patients with and without primary Sjögren's syndrome | Q47595939 | ||
| Association of Trauma and Posttraumatic Stress Disorder With Incident Systemic Lupus Erythematosus in a Longitudinal Cohort of Women | Q47617910 | ||
| Estradiol Sensitizes the Transient Receptor Potential Vanilloid 1 Receptor in Pain Responses | Q47620163 | ||
| Glia- and tissue-specific changes in the Kynurenine Pathway after treatment of mice with lipopolysaccharide and dexamethasone | Q47678641 | ||
| Cardiac ischemia/reperfusion injury is inversely affected by thyroid hormones excess or deficiency in male Wistar rats | Q47730676 | ||
| Upregulation of neuronal kynurenine 3-monooxygenase mediates depression-like behavior in a mouse model of neuropathic pain. | Q47826628 | ||
| Fatigue in Primary Sjögren's Syndrome: Clinical, Laboratory, Psychometric, and Biologic Associations | Q47942672 | ||
| Presence and testosterone influence on the levels of anti- and pro-inflammatory cytokines in lacrimal tissues of a mouse model of Sjögren's syndrome | Q47947553 | ||
| Atypical neurologic complications in patients with primary Sjögren's syndrome: report of 4 cases | Q48093235 | ||
| Inhibitors of kynurenine hydroxylase and kynureninase increase cerebral formation of kynurenate and have sedative and anticonvulsant activities | Q48096292 | ||
| Neurological involvement in primary Sjögren's syndrome: clinical and instrumental evaluation in a cohort of Italian patients | Q48123874 | ||
| Modulation of the kynurenine pathway in search for new neuroprotective agents. Synthesis and preliminary evaluation of (m-nitrobenzoyl)alanine, a potent inhibitor of kynurenine-3-hydroxylase | Q48158088 | ||
| Inhibition of the kynurenine pathway protects against reactive microglial-associated reductions in the complexity of primary cortical neurons | Q48204989 | ||
| Treatment of Sjögren's syndrome-associated dry eye an evidence-based review | Q37860700 | ||
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| Emerging concepts on inhibitors of indoleamine 2,3-dioxygenase in rheumatic diseases | Q38042154 | ||
| 3-Hydroxykynurenine: an intriguing molecule exerting dual actions in the central nervous system | Q38065615 | ||
| Glutamate receptor antibodies in neurological diseases: anti-AMPA-GluR3 antibodies, anti-NMDA-NR1 antibodies, anti-NMDA-NR2A/B antibodies, anti-mGluR1 antibodies or anti-mGluR5 antibodies are present in subpopulations of patients with either: epilep | Q38235715 | ||
| Sjögren syndrome and neuromyelitis optica spectrum disorder co-exist in a common autoimmune milieu | Q38237451 | ||
| Ocular and systemic morbidity in a longitudinal cohort of Sjögren's syndrome | Q38245333 | ||
| The hippocampus and TNF: Common links between chronic pain and depression | Q38412995 | ||
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| TFOS DEWS II Tear Film Report. | Q38652990 | ||
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| The kynurenine pathway and the brain: Challenges, controversies and promises | Q38832497 | ||
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| Psychiatric disorder as clinical presentation of primary Sjögren's syndrome: two case reports | Q39288302 | ||
| MicroRNAs in ocular surface and dry eye diseases: Good, bad and healing situations | Q39292139 | ||
| TFOS DEWS II pain and sensation report. | Q39453338 | ||
| Primary Sjögren's syndrome is associated with significant cognitive dysfunction. | Q39562627 | ||
| A case of primary Sjögren's syndrome presenting primarily with central nervous system vasculitic involvement | Q39971349 | ||
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| Neurological involvement in Primary Sjögren Syndrome | Q40231273 | ||
| Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model | Q40366999 | ||
| Specific Induction of Pulmonary Indoleamine 2,3-Dioxygenase by Bacterial Lipopolysaccharide | Q40437507 | ||
| Central nervous system disease in Sjögren's syndrome. | Q40470363 | ||
| Association of the eosinophilia-myalgia syndrome with the ingestion of tryptophan | Q40763876 | ||
| Pain, xerostomia, and younger age are major determinants of fatigue in Korean patients with primary Sjögren's syndrome: a cohort study | Q40789093 | ||
| Poliovirus induces indoleamine-2,3-dioxygenase and quinolinic acid synthesis in macaque brain | Q41085140 | ||
| Clinical Characteristics of Dry Eye Patients With Chronic Pain Syndromes | Q41099452 | ||
| Endocrine, neural, and immune control of secretory component output by lacrimal gland acinar cells | Q41138911 | ||
| Serotonin hormonally regulates lacrimal gland secretory function via the serotonin type 3a receptor | Q41191875 | ||
| Sex hormones and Sjögren's syndrome. | Q41591330 | ||
| Uptake of 3-hydroxykynurenine measured in rat brain slices and in a neuronal cell line | Q41614480 | ||
| Virus infection induces redistribution and membrane localization of the nuclear antigen La (SS-B): a possible mechanism for autoimmunity. | Q41759956 | ||
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| Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group | Q34523084 | ||
| Tryptophan metabolism in the central nervous system: medical implications | Q34561883 | ||
| Plasticity of the hippocampus: adaptation to chronic stress and allostatic load. | Q34631086 | ||
| 16/6-idiotype expressing antibodies induce brain inflammation and cognitive impairment in mice: the mosaic of central nervous system involvement in lupus | Q34654431 | ||
| IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation | Q34674495 | ||
| Central nervous system abnormalities in fibromyalgia and chronic fatigue syndrome: new concepts in treatment | Q34785212 | ||
| Manipulation of brain kynurenines: glial targets, neuronal effects, and clinical opportunities | Q34863910 | ||
| Sex, stress and the hippocampus: allostasis, allostatic load and the aging process | Q34977028 | ||
| Dysfunction of lacrimal and salivary glands in Sjögren's syndrome: nonimmunologic injury in preinflammatory phase and mouse model | Q35031736 | ||
| Central nervous system mechanisms in Sjögren's syndrome | Q35051526 | ||
| Interferon-γ exacerbates dry eye-induced apoptosis in conjunctiva through dual apoptotic pathways. | Q35221255 | ||
| The Role of N-Methyl-d-Aspartate (NMDA) Receptors in Pain: A Review | Q35538562 | ||
| Weak association between subjective symptoms or and objective testing for dry eyes and dry mouth: results from a population based study | Q35547511 | ||
| Involvement of the peripheral nervous system in primary Sjögren's syndrome | Q35550816 | ||
| Predominant Glandular Cholinergic Dysautonomia in Patients With Primary Sjögren's Syndrome | Q35554428 | ||
| Spinal cord magnetic resonance imaging demonstrates sensory neuronal involvement and clinical severity in neuronopathy associated with Sjögren's syndrome | Q35572519 | ||
| The role of the lacrimal functional unit in the pathophysiology of dry eye. | Q35755146 | ||
| Clinical Characteristics and Outcome of Primary Sjogren's Syndrome: A Large Asian Indian Cohort | Q35824760 | ||
| A Transcriptional Signature of Fatigue Derived from Patients with Primary Sjögren's Syndrome | Q35875673 | ||
| Computational meta-analysis of statistical parametric maps in major depression | Q35917018 | ||
| Molecular Subsetting of Interferon Pathways in Sjögren's Syndrome | Q36001863 | ||
| Type I and II interferon signatures in Sjogren's syndrome pathogenesis: Contributions in distinct clinical phenotypes and Sjogren's related lymphomagenesis | Q36042432 | ||
| Neural signaling in the spleen controls B-cell responses to blood-borne antigen | Q36071721 | ||
| Kynurenine pathway metabolism and the microbiota-gut-brain axis | Q36071899 | ||
| Brain indoleamine 2,3-dioxygenase contributes to the comorbidity of pain and depression | Q36129070 | ||
| The Clinical Characteristics of Primary Sjogren's Syndrome With Neuromyelitis Optica Spectrum Disorder in China: A STROBE-Compliant Article | Q36196691 | ||
| Use of a novel high-resolution magnetic resonance neurography protocol to detect abnormal dorsal root Ganglia in Sjögren patients with neuropathic pain: case series of 10 patients and review of the literature | Q36247817 | ||
| Inhibition of interferon-mediated induction of indoleamine 2,3-dioxygenase in mouse lung by inhibitors of prostaglandin biosynthesis | Q36381631 | ||
| Ocular neuropathic pain | Q36475542 | ||
| Pathophysiology of Sjögren's syndrome | Q36625186 | ||
| Neuropathic Ocular Pain due to Dry Eye is Associated with Multiple Comorbid Chronic Pain Syndromes | Q36642407 | ||
| Peripheral neuropathy in primary sjogren syndrome: a population-based study. | Q53246843 | ||
| Glial and tissue-specific regulation of Kynurenine Pathway dioxygenases by acute stress of mice. | Q53438486 | ||
| The role of B7 family costimulatory molecules and indoleamine 2,3-dioxygenase in primary Sjögren's syndrome and systemic sclerosis. | Q53666361 | ||
| Classification and characterisation of peripheral neuropathies in 102 patients with primary Sjögren's syndrome. | Q53892066 | ||
| The wide spectrum of clinical manifestations in Sjögren's syndrome-associated neuropathy. | Q54074342 | ||
| Kynurenine pathway is altered in patients with SLE and associated with severe fatigue. | Q55035261 | ||
| First-in-Human Phase I Study of the Oral Inhibitor of Indoleamine 2,3-Dioxygenase-1 Epacadostat (INCB024360) in Patients with Advanced Solid Malignancies. | Q55400645 | ||
| Diffusion-weighted MR microimaging of the lacrimal glands in patients with Sjogren's syndrome | Q57187814 | ||
| Nonvasculitic autoimmune inflammatory meningoencephalitis | Q57306398 | ||
| European League Against Rheumatism Sjögren's Syndrome Disease Activity Index and European League Against Rheumatism Sjögren's Syndrome Patient-Reported Index: A Complete Picture of Primary Sjögren's Syndrome Patients | Q57612823 | ||
| Neurological complications of primary Sjögren's syndrome | Q58621918 | ||
| Role of Kynurenine pathway and its metabolites in mood disorders: A systematic review and meta-analysis of clinical studies | Q60062706 | ||
| An update on the role of type I interferons in systemic lupus erythematosus and Sjögrenʼs syndrome | Q60548049 | ||
| Tryptophan metabolism via the kynurenine pathway in patients with the eosinophilia-myalgia syndrome | Q67569120 | ||
| Effects of prolonged duct ligation of the rat salivary glands on the activity of trypsin-like protease | Q68083721 | ||
| The effect of hormones and vitamin B6 on urinary excretion of metabolites of the kynurenine pathway | Q68528934 | ||
| Relationship between the dexamethasone suppression test and the L-tryptophan/competing amino acids ratio in depression | Q69246067 | ||
| Cytotoxicity of 3-hydroxykynurenine in a neuronal hybrid cell line | Q69693682 | ||
| Cytokine regulation of human monocyte differentiation in vitro: the tumor-cytotoxic phenotype induced by macrophage colony-stimulating factor is developmentally regulated by gamma-interferon | Q70720750 | ||
| Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro | Q70790649 | ||
| Comparison of the neurochemical and behavioral effects resulting from the inhibition of kynurenine hydroxylase and/or kynureninase | Q71978453 | ||
| Specific induction of indoleamine 2,3-dioxygenase by bacterial lipopolysaccharide in the mouse lung | Q72101553 | ||
| Ischemic optic neuropathy and high-level anticardiolipin antibodies in primary Sjögren's syndrome | Q72345794 | ||
| Neurotoxin quinolinic acid is selectively elevated in spinal cords of rats with experimental allergic encephalomyelitis | Q72557676 | ||
| Kynurenine 3-hydroxylase in brain: species activity differences and effect of gerbil cerebral ischemia | Q72606002 | ||
| Relationships between lower plasma L-tryptophan levels and immune-inflammatory variables in depression | Q72674139 | ||
| Sjogren syndrome: Central nervous system manifestations | Q72915988 | ||
| Estradiol increases the sensitivity of hippocampal CA1 pyramidal cells to NMDA receptor-mediated synaptic input: correlation with dendritic spine density | Q73067772 | ||
| Salivary and serum interleukin 6 in primary Sjögren's syndrome | Q73442125 | ||
| Alterations in corneal sensitivity and nerve morphology in patients with primary Sjögren's syndrome | Q81151525 | ||
| Neurotrophic keratopathy and diabetes mellitus | Q81332347 | ||
| [Correlation between signals and symptoms of dry eye in Sjögren's syndrome patients] | Q81976452 | ||
| Peripheral neuropathy in an outpatient cohort of patients with Sjögren's syndrome | Q82449072 | ||
| Peripheral neuropathies in Sjogren syndrome: a new reappraisal | Q82966736 | ||
| Neuromyelitis optica--complication or comorbidity in primary Sjögren's syndrome? | Q84086669 | ||
| Treg cells: patrolling a dangerous neighborhood | Q84698041 | ||
| Umbilical cord mesenchymal stem cells inhibit the differentiation of circulating T follicular helper cells in patients with primary Sjögren's syndrome through the secretion of indoleamine 2,3-dioxygenase | Q85211650 | ||
| Human chorionic gonadotropin and indolamine 2,3-dioxygenase in patients with GVHD | Q87572223 | ||
| The tolerogenic peptide hCDR1 immunomodulates cytokine and regulatory molecule gene expression in blood mononuclear cells of primary Sjogren's syndrome patients | Q88579816 | ||
| Bisphenol-A alters microbiota metabolites derived from aromatic amino acids and worsens disease activity during colitis | Q89012434 | ||
| Detection of atrophy of dorsal root ganglion with 3-T magnetic resonance neurography in sensory ataxic neuropathy associated with Sjögren's syndrome | Q89137837 | ||
| Relationship of MR imaging of submandibular glands to hyposalivation in Sjögren's syndrome | Q90200269 | ||
| Central nervous system involvement in primary Sjogren`s syndrome manifesting as multiple sclerosis | Q95583818 | ||
| Primary Sjögren's syndrome with subcortical dementia. | Q48260073 | ||
| Mechanism of delayed increases in kynurenine pathway metabolism in damaged brain regions following transient cerebral ischemia | Q48365971 | ||
| Distribution of the mRNA for a metabotropic glutamate receptor (mGluR1) in the central nervous system: an in situ hybridization study in adult and developing rat | Q48449710 | ||
| The first definition of Sjögren's syndrome. | Q48458104 | ||
| Tryptophan metabolism and immunogenetics in major depression: a role for interferon-γ gene. | Q48484807 | ||
| Association of hippocampal atrophy with cerebrospinal fluid antibodies against the NR2 subtype of the N-methyl-D-aspartate receptor in patients with systemic lupus erythematosus and patients with primary Sjögren's syndrome. | Q48585869 | ||
| Motor weakness and cerebellar ataxia in Sjögren syndrome--identification of antineuronal antibody: a case report. | Q48612951 | ||
| Neuropsychological, neuroimage and psychiatric aspects of primary Sjögren's syndrome. | Q48625661 | ||
| The treatable dementia of Sjögren's syndrome. | Q48694407 | ||
| Chronic corticosterone treatment induces parallel changes in N-methyl-D-aspartate receptor subunit messenger RNA levels and antagonist binding sites in the hippocampus. | Q48702601 | ||
| Serotonin as a modulator of glutamate- and GABA-mediated neurotransmission: implications in physiological functions and in pathology | Q36726602 | ||
| Prevalence of interferon type I signature in CD14 monocytes of patients with Sjogren's syndrome and association with disease activity and BAFF gene expression | Q36745815 | ||
| The immune-mediated alteration of serotonin and glutamate: towards an integrated view of depression | Q36800963 | ||
| Season, sex, age, and education as modifiers of the effects of outdoor air pollution on daily mortality in Shanghai, China: The Public Health and Air Pollution in Asia (PAPA) Study | Q36873537 | ||
| Silencing spinal interneurons inhibits immune suppressive autonomic reflexes caused by spinal cord injury | Q36940634 | ||
| Kynurenine metabolic balance is disrupted in the hippocampus following peripheral lipopolysaccharide challenge | Q36945317 | ||
| Tryptophan metabolism in depression | Q37071928 | ||
| Bacteria activate sensory neurons that modulate pain and inflammation | Q37173782 | ||
| Neuroendocrine dysfunction in Sjogren's syndrome | Q37230802 | ||
| Loss of parasympathetic innervation leads to sustained expression of pro-inflammatory genes in the rat lacrimal gland | Q37258291 | ||
| Kynurenic acid triggers firm arrest of leukocytes to vascular endothelium under flow conditions. | Q37339253 | ||
| Corneal pain without stain: is it real? | Q37392010 | ||
| Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality | Q37460355 | ||
| Cognition, depression, fatigue, and quality of life in primary Sjögren's syndrome: correlations | Q37514488 | ||
| Autonomic dysfunction in primary Sjogren's syndrome: a prospective cohort analysis of 154 Korean patients | Q37559153 | ||
| The contribution of epigenetics in Sjögren's Syndrome | Q37695272 | ||
| Neurological manifestations of primary Sjogren's syndrome | Q37778264 | ||
| P275 | copyright license | Creative Commons Attribution | Q6905323 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | amino acid | Q8066 |
| Sjögren's syndrome | Q335555 | ||
| nervous system | Q9404 | ||
| P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
| P304 | page(s) | 3953 | |
| P577 | publication date | 2018-12-08 | |
| P1433 | published in | International Journal of Molecular Sciences | Q3153277 |
| P1476 | title | Neurological and Inflammatory Manifestations in Sjögren's Syndrome: The Role of the Kynurenine Metabolic Pathway | |
| P478 | volume | 19 |
| Q92814981 | Mechanisms of Disease in Sjögren Syndrome-New Developments and Directions | cites work | P2860 |
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