SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock

scientific article published on 01 January 2019

SUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.CELREP.2018.12.027
P932PMC publication ID6316133
P698PubMed publication ID30605679

P50authorHuib OvaaQ28320514
Alfred VertegaalQ73230597
Monique P C MulderQ84974575
P2093author name stringChristopher L Moore
Matthew D Shoulders
Frauke Liebelt
Rebecca M Sebastian
P2860cites workPARP-1 transcriptional activity is regulated by sumoylation upon heat shockQ24318561
Molecular chaperones as HSF1-specific transcriptional repressorsQ24606489
Systematic and quantitative assessment of the ubiquitin-modified proteomeQ24634631
Phosphorylation of serine 303 is a prerequisite for the stress-inducible SUMO modification of heat shock factor 1Q24685095
Self-propagation of pathogenic protein aggregates in neurodegenerative diseasesQ26996441
System-wide changes to SUMO modifications in response to heat shockQ27865236
Comparative proteomic analysis identifies a role for SUMO in protein quality controlQ27865258
Sumoylation: a regulatory protein modification in health and diseaseQ27865267
An integrated mass spectrometry-based proteomic approach: quantitative analysis of tandem affinity-purified in vivo cross-linked protein complexes (QTAX) to decipher the 26 S proteasome-interacting network.Q27933467
Repression of heat shock transcription factor HSF1 activation by HSP90 (HSP90 complex) that forms a stress-sensitive complex with HSF1Q28118304
Functional heterogeneity of small ubiquitin-related protein modifiers SUMO-1 versus SUMO-2/3Q28145507
Concepts in sumoylation: a decade onQ28257220
Regulation of HSF1 function in the heat stress response: implications in aging and diseaseQ28307651
Transportable, Chemical Genetic Methodology for the Small Molecule-Mediated Inhibition of Heat Shock Factor 1Q28829297
Protocol for micro-purification, enrichment, pre-fractionation and storage of peptides for proteomics using StageTipsQ29614831
Aggresomes, inclusion bodies and protein aggregationQ29615253
Roles of N-linked glycans in the endoplasmic reticulumQ29616458
SUMO fusions and SUMO-specific protease for efficient expression and purification of proteins.Q30342324
Chemical screening methods to identify ligands that promote protein stability, protein crystallization, and structure determinationQ33260141
Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 miceQ33706940
Uncovering global SUMOylation signaling networks in a site-specific mannerQ34041994
Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunctionQ34295237
Molecular chaperone functions in protein folding and proteostasisQ34349321
The biology of proteostasis in aging and diseaseQ34467650
Heat shock factors: integrators of cell stress, development and lifespan.Q36109403
Stress-inducible regulation of heat shock factor 1 by the deacetylase SIRT1Q36194366
O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's diseaseQ36200921
SUMO fusion technology for difficult-to-express proteinsQ36220537
Ubiquitin proteolytic system: focus on SUMO.Q36307179
SUMO under stress.Q37269500
Ubiquitin-like proteinsQ37992156
Sumoylation in neurodegenerative diseasesQ38046126
Label-Free Identification and Quantification of SUMO Target Proteins.Q38746141
Proteotoxic stress reprograms the chromatin landscape of SUMO modification.Q38855621
Ubiquitin-dependent and independent roles of SUMO in proteostasisQ38874015
In vivo aspects of protein folding and quality controlQ38882864
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylationQ39005647
SUMO and the robustness of cancerQ39108925
Ubiquitin: a review on a ubiquitous biofactor in eukaryotic cellsQ39337580
Deep proteome and transcriptome mapping of a human cancer cell lineQ39446248
Dynamic regulation and involvement of the heat shock transcriptional response in arsenic carcinogenesisQ40322991
Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomibQ40431708
OGT functions as a catalytic chaperone under heat stress response: a unique defense role of OGT in hyperthermiaQ40521142
Comparison of SUMO fusion technology with traditional gene fusion systems: enhanced expression and solubility with SUMO.Q41941212
Uncovering the SUMOylation and ubiquitylation crosstalk in human cells using sequential peptide immunopurificationQ42045498
Global analyses of sumoylated proteins in Saccharomyces cerevisiae. Induction of protein sumoylation by cellular stressesQ42931443
The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycleQ45739113
Heat shock protein 27 is involved in SUMO-2/3 modification of heat shock factor 1 and thereby modulates the transcription factor activity.Q45929966
Converging Small Ubiquitin-like Modifier (SUMO) and Ubiquitin Signaling: Improved Methodology Identifies Co-modified Target Proteins.Q47159672
Overproduction of eukaryotic SUMO-1- and SUMO-2-conjugated proteins in Escherichia coliQ47219976
Direct sensing of heat and oxidation by Drosophila heat shock transcription factorQ47693852
Total Chemical Synthesis of SUMO and SUMO-Based Probes for Profiling the Activity of SUMO-Specific ProteasesQ63987411
Recombinant reconstitution of sumoylation reactions in vitroQ83477519
Heat shock induces a massive but differential inactivation of SUMO-specific proteasesQ84740133
P4510describes a project that usesImageJQ1659584
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectproteostasisQ2892805
protein sumoylationQ3503705
molecular chaperonesQ422496
proteasome complexQ14878333
Heat shock factor 1Q21985060
HSP90 [cytosol]Q50251177
P304page(s)236-249.e4
P577publication date2019-01-01
P1433published inCell ReportsQ5058165
P1476titleSUMOylation and the HSF1-Regulated Chaperone Network Converge to Promote Proteostasis in Response to Heat Shock
P478volume26

Reverse relations

cites work (P2860)
Q89876909Chemical Biology Framework to Illuminate Proteostasis
Q91720997Inhibiting ubiquitination causes an accumulation of SUMOylated newly synthesized nuclear proteins at PML bodies
Q98626201Mechanisms of sensing and response to proteotoxic stress
Q100391119SUMOylation of PUM2 promotes the vasculogenic mimicry of glioma cells via regulating CEBPD

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