Nutrient-Dependent Changes of Protein Palmitoylation: Impact on Nuclear Enzymes and Regulation of Gene Expression

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Nutrient-Dependent Changes of Protein Palmitoylation: Impact on Nuclear Enzymes and Regulation of Gene Expression is …
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scholarly articleQ13442814

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P356DOI10.3390/IJMS19123820
P932PMC publication ID6320809
P698PubMed publication ID30513609

P50authorMatteo SpinelliQ60962247
Claudio GrassiQ42889602
Salvatore FuscoQ56863283
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The physiology of protein S-acylationQ27014134
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Plasmodium falciparum Sir2A Preferentially Hydrolyzes Medium and Long Chain Fatty Acyl LysineQ27674991
Palmitoylation of TEAD Transcription Factors Is Required for Their Stability and Function in Hippo Pathway SignalingQ27703281
Identification of a Ras palmitoyltransferase in Saccharomyces cerevisiae.Q27931414
Global analysis of protein palmitoylation in yeastQ27937597
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N-myristoyltransferaseQ28138664
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Effect of C-Terminal S-Palmitoylation on D2 Dopamine Receptor Trafficking and StabilityQ28550695
CD36 is palmitoylated on both N- and C-terminal cytoplasmic tailsQ28609742
CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine AcetylationQ28818241
ZDHHC7-mediated S-palmitoylation of Scribble regulates cell polarityQ28829707
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Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranesQ33598012
Acetylation of tau inhibits its degradation and contributes to tauopathyQ33703231
Palmitoylation of oncogenic NRAS is essential for leukemogenesisQ33839862
17β-Estradiol regulates insulin-degrading enzyme expression via an ERβ/PI3-K pathway in hippocampus: relevance to Alzheimer's preventionQ33927741
Tandem fluorescence imaging of dynamic S-acylation and protein turnoverQ33928339
Proteomic Analysis of Fatty-acylated Proteins in Mammalian Cells with Chemical Reporters Reveals S-Acylation of Histone H3 VariantsQ34024729
Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal modelQ34244907
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Memory and synaptic deficits in Hip14/DHHC17 knockout mice.Q37395240
Regulation of Ras localization and cell transformation by evolutionarily conserved palmitoyltransferasesQ37546926
Insulin-regulated protein palmitoylation impacts endothelial cell function.Q37636062
Protein S-palmitoylation in cellular differentiationQ37643588
Membrane rafts in Alzheimer's disease beta-amyloid productionQ37715176
Dynamic epigenetic regulation in neurons: enzymes, stimuli and signaling pathwaysQ37803122
DHHC palmitoyl transferases: substrate interactions and (patho)physiologyQ37851213
Regulation of glucose transport by insulin: traffic control of GLUT4.Q38012259
The role of palmitoylation in regulating Ras localization and function.Q38077211
Lysine acetyltransferases CBP and p300 as therapeutic targets in cognitive and neurodegenerative disorders.Q38085375
Chemical reporters for biological discoveryQ38122638
Acetyl-CoA and the regulation of metabolism: mechanisms and consequences.Q38363821
ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization.Q38510913
Protein S-palmitoylation and cancer.Q38538067
Protein prenylation: unique fats make their mark on biologyQ38704283
TEAD1 enhances proliferation via activating SP1 in colorectal cancer.Q38738788
New insights into the posttranslational regulation of human cytosolic thioredoxin by S-palmitoylationQ38891266
A Lipid-Anchored NAC Transcription Factor Is Translocated into the Nucleus and Activates Glyoxalase I Expression during Drought Stress.Q38978627
Tead2 expression levels control the subcellular distribution of Yap and Taz, zyxin expression and epithelial-mesenchymal transitionQ39022341
Post-translational modifications of proteins: acetylcholinesterase as a model systemQ34418483
Alzheimer's disease risk genes and mechanisms of disease pathogenesisQ34425904
The intracellular dynamic of protein palmitoylationQ34439629
Huntington disease: pathogenesis and treatmentQ34450055
Promoting health and longevity through diet: from model organisms to humansQ34468959
Protein palmitoylation by a family of DHHC protein S-acyltransferasesQ34508328
Sequence dependence of protein isoprenylationQ34593893
Minireview: Extranuclear Steroid Receptors: Roles in Modulation of Cell FunctionsQ34609967
Protein prenylation: enzymes, therapeutics, and biotechnology applicationsQ34992469
Acyl-CoA:lysophosphatidylcholine acyltransferase I (Lpcat1) catalyzes histone protein O-palmitoylation to regulate mRNA synthesisQ35150069
Palmitoylation controls the dynamics of budding-yeast heterochromatin via the telomere-binding protein Rif1.Q35198141
The role of dynamic palmitoylation in Ca2+ channel inactivationQ35203906
Minireview: the AMP-activated protein kinase cascade: the key sensor of cellular energy status.Q35213694
Modulation of hippocampal neural plasticity by glucose-related signalingQ35568177
SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasiaQ35572506
A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to calorie restrictionQ35673630
Nuclear import of a lipid-modified transcription factor: mobilization of NFAT5 isoform a by osmotic stressQ35694625
Curation of the Mammalian Palmitoylome Indicates a Pivotal Role for Palmitoylation in Diseases and Disorders of the Nervous System and CancersQ35746623
Increased EID1 nuclear translocation impairs synaptic plasticity and memory function associated with pathogenesis of Alzheimer's diseaseQ35748624
DHHC protein S-acyltransferases use similar ping-pong kinetic mechanisms but display different acyl-CoA specificitiesQ35801901
S- to N-Palmitoyl Transfer During Proteomic Sample PreparationQ35884804
A role for aberrant protein palmitoylation in FFA-induced ER stress and β-cell deathQ36041872
Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutantQ36053924
The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domainQ36236290
Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic StrategyQ36320570
Insulin signaling and the regulation of glucose transport.Q36321818
The emerging role of nuclear architecture in DNA repair and genome maintenanceQ36340722
Continuous dopamine-receptor treatment of Parkinson's disease: scientific rationale and clinical implicationsQ36542313
Autopalmitoylation of TEAD proteins regulates transcriptional output of the Hippo pathwayQ36703469
Dynamic palmitoylation links cytosol-membrane shuttling of acyl-protein thioesterase-1 and acyl-protein thioesterase-2 with that of proto-oncogene H-ras product and growth-associated protein-43.Q36724996
Protein-protein interactions in the assembly and subcellular trafficking of the BACE (beta-site amyloid precursor protein-cleaving enzyme) complex of Alzheimer's disease.Q36979496
Neural palmitoyl-proteomics reveals dynamic synaptic palmitoylationQ37030648
Palmitoylation of amyloid precursor protein regulates amyloidogenic processing in lipid raftsQ37032450
Insulin in combination with other diabetes medication is associated with less Alzheimer neuropathologyQ37178970
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue12
P407language of work or nameEnglishQ1860
P304page(s)3820
P577publication date2018-11-30
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleNutrient-Dependent Changes of Protein Palmitoylation: Impact on Nuclear Enzymes and Regulation of Gene Expression
P478volume19

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cites work (P2860)
Q101237379A large deletion on CFA28 omitting ACSL5 gene is associated with intestinal lipid malabsorption in the Australian Kelpie dog breed
Q89766120S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells

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