| review article | Q7318358 |
| scholarly article | Q13442814 |
| P356 | DOI | 10.1016/S0952-7915(98)80121-0 |
| P698 | PubMed publication ID | 9722923 |
| P50 | author | Fabienne Tacchini-Cottier | Q43937349 |
| P2093 | author name string | J Louis | |
| P Launois | |||
| H Himmelrich | |||
| C Parra-Lopez | |||
| P2860 | cites work | A functional interleukin 12 receptor complex is composed of two beta-type cytokine receptor subunits | Q24323368 |
| Multiple defects of immune cell function in mice with disrupted interferon-gamma genes | Q28267397 | ||
| Functional diversity of helper T lymphocytes | Q29619415 | ||
| Defective IgE production by SJL mice is linked to the absence of CD4+, NK1.1+ T cells that promptly produce interleukin 4 | Q33734319 | ||
| Interferon gamma-independent effects of interleukin 12 administered during acute or established infection due to Leishmania major | Q36013244 | ||
| The adjuvant effect of interleukin-12 in a vaccine against Leishmania major. | Q54216858 | ||
| IL-4 Rapidly Produced by Vβ4 Vα8 CD4+ T Cells Instructs Th2 Development and Susceptibility to Leishmania major in BALB/c Mice | Q56987174 | ||
| Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from αβ TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-γ production is IFN-γ-dependent | Q56987689 | ||
| Infection with Leishmania major induces interleukin-12 production in vivo | Q58824998 | ||
| Immune response in mice that lack the interferon-gamma receptor | Q62022366 | ||
| In susceptible mice, Leishmania major induce very rapid interleukin-4 production by CD4+ T cells which are NK1.1- | Q70911092 | ||
| Genetic susceptibility to Leishmania: IL-12 responsiveness in TH1 cell development | Q70960222 | ||
| Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunity | Q71066501 | ||
| CD40 ligand is required for protective cell-mediated immunity to Leishmania major | Q71066505 | ||
| IL-12-deficient mice are defective in IFN gamma production and type 1 cytokine responses | Q71079171 | ||
| Resistance to Leishmania major induced by tolerance to a single antigen | Q71595277 | ||
| Blockade of CD86 ameliorates Leishmania major infection by down-regulating the Th2 response | Q71825823 | ||
| Production of nitric oxide and superoxide by activated macrophages and killing of Leishmania major | Q72285880 | ||
| Multistage regulation of Th1-type immune responses by the transcription factor IRF-1 | Q73479951 | ||
| Interferon regulatory factor-1 is required for a T helper 1 immune response in vivo | Q73479956 | ||
| The resolution of lesions induced by Leishmania major in mice requires a functional Fas (APO-1, CD95) pathway of cytotoxicity | Q74251693 | ||
| The presence of interleukin 4 during in vitro priming determines the lymphokine-producing potential of CD4+ T cells from T cell receptor transgenic mice | Q36231820 | ||
| Recombinant interleukin 12 cures mice infected with Leishmania major | Q36361742 | ||
| Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response | Q36361808 | ||
| Natural killer cells are a source of interferon gamma that drives differentiation of CD4+ T cell subsets and induces early resistance to Leishmania major in mice | Q36362141 | ||
| Leishmania promastigotes evade interleukin 12 (IL-12) induction by macrophages and stimulate a broad range of cytokines from CD4+ T cells during initiation of infection | Q36362701 | ||
| CD4+ effector cells default to the Th2 pathway in interferon gamma-deficient mice infected with Leishmania major | Q36362926 | ||
| T cell genetic background determines default T helper phenotype development in vitro | Q36364428 | ||
| Mice from a genetically resistant background lacking the interferon gamma receptor are susceptible to infection with Leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response | Q36364501 | ||
| Leishmania promastigotes selectively inhibit interleukin 12 induction in bone marrow-derived macrophages from susceptible and resistant mice | Q36366305 | ||
| Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthase | Q36366480 | ||
| Limited role of CD28-mediated signals in T helper subset differentiation | Q36367295 | ||
| Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses | Q36367480 | ||
| Regulation of the interleukin (IL)-12R beta 2 subunit expression in developing T helper 1 (Th1) and Th2 cells | Q36376864 | ||
| Resistance to Leishmania major is linked to the H2 region on chromosome 17 and to chromosome 9 | Q36377170 | ||
| Regulation of interleukin-12 by complement receptor 3 signaling | Q36377284 | ||
| Selective suppression of interleukin-12 induction after macrophage receptor ligation | Q36377302 | ||
| A role for CD4 in peripheral T cell differentiation | Q36380288 | ||
| Selective expression of a stable cell surface molecule on type 2 but not type 1 helper T cells | Q36400414 | ||
| Interleukin 12 acts directly on CD4+ T cells to enhance priming for interferon gamma production and diminishes interleukin 4 inhibition of such priming | Q36638672 | ||
| Expression cloning of a protective Leishmania antigen | Q36701227 | ||
| Genetic mapping of a murine locus controlling development of T helper 1/T helper 2 type responses | Q37241858 | ||
| Fas-mediated cytotoxicity--a new immunoregulatory and pathogenic function of Th1 CD4+ T cells | Q40378902 | ||
| The regulation of immunity to Leishmania major | Q40444839 | ||
| The role of natural killer cells in host-parasite interactions | Q40540042 | ||
| Effect of IL-4 and IL-13 on IFN-gamma-induced production of nitric oxide in mouse macrophages infected with herpes simplex virus type 2. | Q41090130 | ||
| Natural killer cells: from no receptors to too many | Q41457022 | ||
| Cytokines induce the development of functionally heterogeneous T helper cell subsets | Q41732572 | ||
| IL-4-deficient Balb/c mice resist infection with Leishmania major | Q42943751 | ||
| The transcription factor interferon regulatory factor-1 is essential for natural killer cell function in vivo | Q42943882 | ||
| Serial backcross mapping of multiple loci associated with resistance to Leishmania major in mice | Q43532810 | ||
| Defective NK cell activity and Th1 response in IL-18-deficient mice | Q43595287 | ||
| Type 1 interferon (IFNalpha/beta) and type 2 nitric oxide synthase regulate the innate immune response to a protozoan parasite | Q44248030 | ||
| Altered immune responses in mice lacking inducible nitric oxide synthase | Q44662136 | ||
| Role of NK1.1+ T cells in a TH2 response and in immunoglobulin E production | Q44684458 | ||
| IGIF does not drive Th1 development but synergizes with IL-12 for interferon-gamma production and activates IRAK and NFkappaB. | Q45933733 | ||
| Impaired Th2 subset development in the absence of CD4. | Q46572898 | ||
| Developmental commitment to the Th2 lineage by extinction of IL-12 signaling. | Q51123887 | ||
| Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection. | Q52519428 | ||
| Genetically resistant mice lacking interleukin-12 are susceptible to infection with Leishmania major and mount a polarized Th2 cell response. | Q52520769 | ||
| P433 | issue | 4 | |
| P921 | main subject | Leishmania major | Q1950715 |
| P304 | page(s) | 459-464 | |
| P577 | publication date | 1998-08-01 | |
| P1433 | published in | Current Opinion in Immunology | Q15752917 |
| P1476 | title | Regulation of protective immunity against Leishmania major in mice | |
| P478 | volume | 10 |
| Q47993991 | A mixed Th1/Th2 response elicited by a liposomal formulation of Leishmania vaccine instructs Th1 responses and resistance to Leishmania donovani in susceptible BALB/c mice |
| Q46899191 | Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. |
| Q57200992 | Aluminium phosphate potentiates the efficacy of DNA vaccines against Leishmania mexicana |
| Q35927465 | CD8(+) T cells in leishmania infections: friends or foes? |
| Q24806926 | Cell fate decision: T-helper 1 and 2 subsets in immune responses |
| Q73861414 | Characterizing cellular immune response to kinetoplastid membrane protein-11 (KMP-11) during Leishmania (Viannia) panamensis infection using dendritic cells (DCs) as antigen presenting cells (APCs) |
| Q56749751 | Co-administration of IL-12 DNA with rORFF antigen confers long-term protective immunity against experimental visceral leishmaniaisis |
| Q34003750 | Comparison of the immune profile of nonhealing cutaneous Leishmaniasis patients with those with active lesions and those who have recovered from infection |
| Q47851462 | Cross-talk between CD8(+) and CD4(+) T cells in experimental cutaneous leishmaniasis: CD8(+) T cells are required for optimal IFN-gamma production by CD4(+) T cells |
| Q36915067 | DNA Vaccines against Protozoan Parasites: Advances and Challenges |
| Q40599543 | Effect of Salmonella-infected human monocytes on natural killer cell cytotoxicity. In vitro studies. |
| Q57258462 | Effective clearance of intracellularLeishmania majorin vivo requires Pten in macrophages |
| Q51945644 | Effective humoral and cellular immunoprotective responses in Li ESAp-MDP vaccinated protected dogs. |
| Q43183904 | Evaluation of localized and systemic immune responses in cutaneous leishmaniasis caused by Leishmania tropica: interleukin-8, monocyte chemotactic protein-1 and nitric oxide are major regulatory factors |
| Q58846857 | IFN-gamma, IL-4, IL-10 and IL-12 gene expression in BCG-Leishmania vaccination of Trypanosoma cruzi-infected mice |
| Q81049997 | Immunization strategies against visceral leishmaniosis with the nucleosomal histones of Leishmania infantum encoded in DNA vaccine or pulsed in dendritic cells |
| Q34128082 | Immunization with a polyprotein vaccine consisting of the T-Cell antigens thiol-specific antioxidant, Leishmania major stress-inducible protein 1, and Leishmania elongation initiation factor protects against leishmaniasis |
| Q45334801 | In vitro initial immune response against Leishmania amazonensis infection is characterized by an increased production of IL-10 and IL-13. |
| Q34726014 | Is 'timing' important for cytokine polarization? |
| Q34127073 | Leishmania priming of human dendritic cells for CD40 ligand-induced interleukin-12p70 secretion is strain and species dependent |
| Q34959725 | Neospora caninum: a cause of immune-mediated failure of pregnancy? |
| Q47644495 | New methods and software tools for high throughput CDR3 spectratyping. Application to T lymphocyte repertoire modifications during experimental malaria. |
| Q51812069 | Non PC liposome entrapped promastigote antigens elicit parasite specific CD8+ and CD4+ T-cell immune response and protect hamsters against visceral leishmaniasis. |
| Q74558971 | PI3K-mediated negative feedback regulation of IL-12 production in DCs |
| Q37128771 | Persistent parasites and immunologic memory in cutaneous leishmaniasis: implications for vaccine designs and vaccination strategies. |
| Q39515412 | Potentiality of interleukin-18 as a useful reagent for treatment and prevention of Leishmania major infection |
| Q46394444 | Protection against experimental visceral leishmaniasis infection in dogs immunized with purified excreted secreted antigens of Leishmania infantum promastigotes |
| Q38015852 | Protective immunity and vaccination against cutaneous leishmaniasis. |
| Q44022754 | Recombinant cysteine proteinases-based vaccines against Leishmania major in BALB/c mice: the partial protection relies on interferon gamma producing CD8(+) T lymphocyte activation |
| Q40038032 | Regulatory T-cell profile in early and late lesions of cutaneous leishmaniasis due to Leishmania major |
| Q34560563 | Role of cytokines in the innate immune response to intracellular pathogens |
| Q39516796 | Suppression of gamma interferon transcription and production by nematode excretory-secretory antigen during polyclonal stimulation of rat lymph node T cells |
| Q36376320 | The Leishmania infantum acidic ribosomal protein P0 administered as a DNA vaccine confers protective immunity to Leishmania major infection in BALB/c mice |
| Q37402425 | The prominent role of neutrophils during the initial phase of infection by Leishmania parasites |
| Q34033888 | Toward a novel experimental model of infection to study American cutaneous leishmaniasis caused by Leishmania braziliensis |
| Q73739659 | Visceral leishmaniasis in a patient with acquired hypogammaglobulinemia |
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