Lipid Uptake by Alveolar Macrophages Drives Fibrotic Responses to Silica Dust

scientific article published in Scientific Reports

Lipid Uptake by Alveolar Macrophages Drives Fibrotic Responses to Silica Dust is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1111614935
P356DOI10.1038/S41598-018-36875-2
P932PMC publication ID6344530
P698PubMed publication ID30674959

P2093author name stringJie Cui
Hong Xu
Ying Tian
Ross Summer
Xiaomin Hou
Jingjing Ma
Hongli Wang
Lingli Guo
Heliang Liu
Xiaohui Hao
Ziying Chen
P2860cites workCut-off values and significance of Oil Red O-positive cells in bronchoalveolar lavage fluidQ43277904
Atorvastatin enhances cellular uptake of oxidized LDL in adipocytes from hypercholesterolemic rabbitsQ44701124
Defective extracellular pyrophosphate metabolism promotes vascular calcification in a mouse model of Hutchinson-Gilford progeria syndrome that is ameliorated on pyrophosphate treatmentQ45770191
Matrix Stiffness: the Conductor of Organ FibrosisQ47724285
Inhibitory effects of Dioscin on atherosclerosis and foam cell formation in hyperlipidemia ratsQ50211990
Simvastatin inhibited oxLDL-induced proatherogenic effects through calpain-1-PPARγ-CD36 pathway.Q51402715
Ly6ChiMonocytes Direct Alternatively Activated Profibrotic Macrophage Regulation of Lung FibrosisQ61971062
Cellular immunity, low-density lipoprotein and atherosclerosis: break of tolerance in the artery wallQ85054596
MicroRNA-27a/b regulates cellular cholesterol efflux, influx and esterification/hydrolysis in THP-1 macrophagesQ87415265
Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophagesQ24310677
Structure of LIMP-2 provides functional insights with implications for SR-BI and CD36Q24338905
Lipid-induced insulin resistance is associated with increased monocyte expression of scavenger receptor CD36 and internalization of oxidized LDL.Q33719103
Regulation of foam cells by adenosine.Q34031160
Nrf2, a PPARγ alternative pathway to promote CD36 expression on inflammatory macrophages: implication for malariaQ34031187
Autophagy: an emerging therapeutic target in vascular diseasesQ35484237
A pneumocyte-macrophage paracrine lipid axis drives the lung toward fibrosis.Q36049500
Inhaling medicines: delivering drugs to the body through the lungsQ36694800
CD36, but not G2A, modulates efferocytosis, inflammation, and fibrosis following bleomycin-induced lung injuryQ36709598
Compare the effect of eicosapentaenoic acid and oxidized low-density lipoprotein on the expression of CD36 and peroxisome proliferator-activated receptor gammaQ36916221
Transforming growth factor-β (TGF-β)-mediated connective tissue growth factor (CTGF) expression in hepatic stellate cells requires Stat3 signaling activationQ37234131
Mechanisms and consequences of macrophage apoptosis in atherosclerosisQ37308942
Role of macrophage scavenger receptors in atherosclerosisQ37995838
Oxidized low density lipoprotein, stem cells, and atherosclerosisQ38022767
Reduction of lipid-laden macrophage index after laparoscopic Nissen fundoplication in cystic fibrosis patients after lung transplantationQ38045950
Foam cells in atherosclerosisQ38115664
The impact of dietary fatty acids on macrophage cholesterol homeostasis.Q38180274
Quercetin protects macrophages from oxidized low-density lipoprotein-induced apoptosis by inhibiting the endoplasmic reticulum stress-C/EBP homologous protein pathwayQ38323245
Astaxanthin functions differently as a selective peroxisome proliferator-activated receptor γ modulator in adipocytes and macrophagesQ38324137
Anti-atherosclerotic potential of baicalin mediated by promoting cholesterol efflux from macrophages via the PPARγ-LXRα-ABCA1/ABCG1 pathwayQ38738825
Chrysin inhibits foam cell formation through promoting cholesterol efflux from RAW264.7 macrophages.Q38889297
Propofol up-regulates expression of ABCA1, ABCG1, and SR-B1 through the PPARγ/LXRα signaling pathway in THP-1 macrophage-derived foam cellsQ38918670
Emodin enhances cholesterol efflux by activating peroxisome proliferator-activated receptor-γ in oxidized low density lipoprotein-loaded THP1 macrophagesQ38994153
Pentraxin 3 promotes oxLDL uptake and inhibits cholesterol efflux from macrophage-derived foam cellsQ39011075
Glutathione redox regulates TGF-beta-induced fibrogenic effects through Smad3 activationQ39902670
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)399
P577publication date2019-01-23
P1433published inScientific ReportsQ2261792
P1476titleLipid Uptake by Alveolar Macrophages Drives Fibrotic Responses to Silica Dust
P478volume9

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cites work (P2860)
Q96128937Alveolar lipids in pulmonary disease. A review
Q94463922Decreased Soluble Receptor of Advanced Glycation End Product Levels Correlated with Inflammation in Silicosis
Q92460563The Protective Role of Tanshinone IIA in Silicosis Rat Model via TGF-β1/Smad Signaling Suppression, NOX4 Inhibition and Nrf2/ARE Signaling Activation

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