scholarly article | Q13442814 |
P50 | author | Frédéric Checler | Q38321085 |
Cristine Alves da Costa | Q40270055 | ||
P2093 | author name string | Eric Duplan | |
Lila Rouland | |||
P2860 | cites work | SUMO-1 modification of the acute promyelocytic leukaemia protein PML: implications for nuclear localisation | Q22008651 |
Mdm2 is a RING finger-dependent ubiquitin protein ligase for itself and p53 | Q22253350 | ||
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase | Q22254584 | ||
Cloning and characterization of LUN, a novel ring finger protein that is highly expressed in lung and specifically binds to a palindromic sequence | Q24291022 | ||
PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease | Q24294809 | ||
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1 | Q24297155 | ||
Parkin mediates neuroprotection through activation of IkappaB kinase/nuclear factor-kappaB signaling | Q24297849 | ||
Parkin ubiquitinates and promotes the degradation of RanBP2 | Q24298223 | ||
Autoregulation of Parkin activity through its ubiquitin-like domain | Q24307382 | ||
mel-18, a Polycomb group-related mammalian gene, encodes a transcriptional negative regulator with tumor suppressive activity | Q24310321 | ||
A small ubiquitin-related polypeptide involved in targeting RanGAP1 to nuclear pore complex protein RanBP2 | Q24317523 | ||
Mdm2 promotes the rapid degradation of p53 | Q24322597 | ||
Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription. | Q51533923 | ||
Transcriptional alterations in skin fibroblasts from Parkinson's disease patients with parkin mutations. | Q51765978 | ||
SUMOylation, aging and autophagy in neurodegeneration. | Q51766687 | ||
The Cellular Protein Level of Parkin Is Regulated by Its Ubiquitin-like Domain | Q57371863 | ||
Recombinant human MDM2 oncoprotein shows sequence composition selectivity for binding to both RNA and DNA | Q62599757 | ||
Nitrosative and oxidative stress links dysfunctional ubiquitination to Parkinson's disease | Q81045087 | ||
Parkin modulates gene expression in control and ceramide-treated PC12 cells | Q83198040 | ||
Conjugation with the ubiquitin-related modifier SUMO-1 regulates the partitioning of PML within the nucleus | Q24532901 | ||
Identification and preliminary characterization of a protein motif related to the zinc finger | Q24563322 | ||
JASPAR 2016: a major expansion and update of the open-access database of transcription factor binding profiles | Q24700982 | ||
Ageing and Parkinson's disease: why is advancing age the biggest risk factor? | Q27021628 | ||
SUMO1 Affects Synaptic Function, Spine Density and Memory | Q27308933 | ||
Mechanisms of mitophagy | Q27310261 | ||
Structure of the human Parkin ligase domain in an autoinhibited state | Q27678455 | ||
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases | Q27678625 | ||
Structure of parkin reveals mechanisms for ubiquitin ligase activation | Q27684576 | ||
RAD6-dependent DNA repair is linked to modification of PCNA by ubiquitin and SUMO. | Q27937465 | ||
Massively parallel measurements of molecular interaction kinetics on a microfluidic platform | Q27938491 | ||
Yeast DNA repair proteins Rad6 and Rad18 form a heterodimer that has ubiquitin conjugating, DNA binding, and ATP hydrolytic activities | Q27938794 | ||
S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease | Q28116512 | ||
Molecular cloning and characterization of a novel protein kinase C-interacting protein with structural motifs related to RBCC family proteins | Q28567239 | ||
The RING finger protein SNURF is a bifunctional protein possessing DNA binding activity | Q28573009 | ||
PINK1-phosphorylated mitofusin 2 is a Parkin receptor for culling damaged mitochondria | Q28592217 | ||
TFCat: the curated catalog of mouse and human transcription factors | Q28752619 | ||
Genome-wide mapping of in vivo protein-DNA interactions | Q29547162 | ||
A census of human transcription factors: function, expression and evolution | Q29622841 | ||
Immunodetection of Parkin protein in vertebrate and invertebrate brains: a comparative study using specific antibodies | Q31926278 | ||
Loss of Parkin reduces inflammatory arthritis by inhibiting p53 degradation | Q33555712 | ||
Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients | Q33861614 | ||
Presenilins: multifunctional proteins involved in Alzheimer's disease pathology | Q33904253 | ||
Transcriptional repression of p53 by parkin and impairment by mutations associated with autosomal recessive juvenile Parkinson's disease. | Q34189618 | ||
Gene regulation and DNA damage in the ageing human brain | Q34326236 | ||
Electrophoretic mobility shift assay of zinc finger proteins: competition for Zn(2+) bound to Sp1 in protocols including EDTA. | Q34778208 | ||
Presenilins and γ-secretase: structure, function, and role in Alzheimer Disease | Q35658184 | ||
SUMO1 promotes Aβ production via the modulation of autophagy | Q35853044 | ||
Functional characterization of Rad18 domains for Rad6, ubiquitin, DNA binding and PCNA modification | Q36082927 | ||
The p53 response element and transcriptional repression | Q37693593 | ||
Gene-environment interactions in Parkinson's disease and other forms of parkinsonism | Q37739520 | ||
Determining the specificity of protein–DNA interactions | Q37793836 | ||
Methods for Analysis of Transcription Factor DNA-Binding Specificity In Vitro | Q37873862 | ||
To repress or not to repress: this is the guardian's question | Q37878048 | ||
Mitophagy and Parkinson's disease: be eaten to stay healthy | Q38038443 | ||
p53 in neurodegenerative diseases and brain cancers | Q38167220 | ||
Beyond γ-secretase activity: The multifunctional nature of presenilins in cell signalling pathways | Q38615871 | ||
ER-stress-associated functional link between Parkin and DJ-1 via a transcriptional cascade involving the tumor suppressor p53 and the spliced X-box binding protein XBP-1. | Q39187400 | ||
Parkin promotes the ubiquitination and degradation of the mitochondrial fusion factor mitofusin 1. | Q39536018 | ||
Parkin protects mitochondrial genome integrity and supports mitochondrial DNA repair | Q39823278 | ||
DNA damage induces nuclear translocation of parkin | Q39823990 | ||
Identification of ubiquitin ligase activity of RBCK1 and its inhibition by splice variant RBCK2 and protein kinase Cbeta. | Q40008621 | ||
β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models | Q40170480 | ||
Functional modulation of parkin through physical interaction with SUMO-1. | Q40235074 | ||
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI(3)K-Akt signalling | Q40252247 | ||
Parkin suppresses the expression of monoamine oxidases | Q40321332 | ||
Parkin enhances mitochondrial biogenesis in proliferating cells | Q40322753 | ||
Processing of the beta-amyloid precursor protein and its regulation in Alzheimer's disease | Q40414917 | ||
Parkin phosphorylation and modulation of its E3 ubiquitin ligase activity | Q40489168 | ||
RING finger 1 mutations in Parkin produce altered localization of the protein | Q40629977 | ||
Parkin expression in the adult mouse brain | Q40836565 | ||
Parkin suppresses c-Jun N-terminal kinase-induced cell death via transcriptional regulation in Drosophila | Q43056002 | ||
Identification of a novel Zn2+-binding domain in the autosomal recessive juvenile Parkinson-related E3 ligase parkin. | Q43123357 | ||
Parkin targets HIF-1α for ubiquitination and degradation to inhibit breast tumor progression. | Q47132104 | ||
Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation | Q47850913 | ||
Parkin functionally interacts with PGC-1α to preserve mitochondria and protect dopaminergic neurons | Q48005750 | ||
Expression of novel DNA-binding protein with zinc finger structure in various tumor cells | Q48248073 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | DNA binding | Q14633858 |
Parkinson's disease | Q11085 | ||
transcription factor | Q407384 | ||
regulation of gene expression | Q411391 | ||
ubiquitin ligase | Q4274835 | ||
P304 | page(s) | 965 | |
P577 | publication date | 2018-01-01 | |
P1433 | published in | Frontiers in Neuroscience | Q2177807 |
P1476 | title | The Transcription Factor Function of Parkin: Breaking the Dogma | |
P478 | volume | 12 |
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