Proposed mechanism for the length dependence of the force developed in maximally activated muscles

scientific article published in Scientific Reports

Proposed mechanism for the length dependence of the force developed in maximally activated muscles is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/S41598-018-36706-4
P932PMC publication ID6362285
P698PubMed publication ID30718530

P50authorTakumi WashioQ86433189
Lorenzo MarcucciQ88244958
P2093author name stringToshio Yanagida
P2860cites workThe variation in isometric tension with sarcomere length in vertebrate muscle fibresQ24540344
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Mechanosensing in Myosin Filament Solves a 60 Years Old Conflict in Skeletal Muscle Modeling between High Power Output and Slow Rise in TensionQ28829248
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Visualization of cardiac muscle thin filaments and measurement of their lengths by electron tomographyQ30851629
Myosin ATP turnover rate is a mechanism involved in thermogenesis in resting skeletal muscle fibersQ33591667
A molecular model of phosphorylation-based activation and potentiation of tarantula muscle thick filamentsQ34035392
Proposed mechanism of force generation in striated muscleQ34223986
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Myosin-binding protein C corrects an intrinsic inhomogeneity in cardiac excitation-contraction couplingQ35234607
The giant protein titin: a major player in myocardial mechanics, signaling, and diseaseQ35672016
Including Thermal Fluctuations in Actomyosin Stable States Increases the Predicted Force per Motor and Macroscopic Efficiency in Muscle ModellingQ36132279
The molecular mechanism of muscle contraction.Q36288552
The relationship between contractile force and intracellular [Ca2+] in intact rat cardiac trabeculaeQ36411582
Titin strain contributes to the Frank-Starling law of the heart by structural rearrangements of both thin- and thick-filament proteinsQ36646689
Size and speed of the working stroke of cardiac myosin in situQ36770707
The cellular basis of the length-tension relation in cardiac muscleQ39830305
Titin-mediated thick filament activation, through a mechanosensing mechanism, introduces sarcomere-length dependencies in mathematical models of rat trabecula and whole ventricleQ41038389
Thick filament mechano-sensing is a calcium-independent regulatory mechanism in skeletal muscleQ41670785
Myosin filament activation in the heart is tuned to the mechanical task.Q41710182
Distinct contributions of the thin and thick filaments to length-dependent activation in heart muscleQ41957734
Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes.Q42204804
Muscle contraction: A mechanical perspectiveQ42915666
Upregulation of TRPC1 contributes to contractile function in isoproterenol-induced hypertrophic myocardium of rat.Q45328769
Attached molecular motor in a trapped single molecule assay as a bidimensional Brownian multistable systemQ45878916
Lessons from a tarantula: new insights into myosin interacting-heads motif evolution and its implications on diseaseQ46312164
Minimum number of myosin motors accounting for shortening velocity under zero load in skeletal muscle.Q48053831
Hypertrophic cardiomyopathy mutation R58Q in the myosin regulatory light chain perturbs thick filament-based regulation in cardiac muscleQ49923294
Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments.Q51648911
Muscular contractionQ68871933
Muscle structure and theories of contractionQ74709864
Cooperative activation in cardiac muscle: impact of sarcomere lengthQ77612961
Comparison of putative cooperative mechanisms in cardiac muscle: length dependence and dynamic responsesQ77756274
On the mechanical factors which determine the output of the ventriclesQ80323314
A 3D diffusional-compartmental model of the calcium dynamics in cytosol, sarcoplasmic reticulum and mitochondria of murine skeletal muscle fibersQ90499344
Deciphering the super relaxed state of human β-cardiac myosin and the mode of action of mavacamten from myosin molecules to muscle fibersQ90927100
The failing human heart is unable to use the Frank-Starling mechanismQ93874564
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)1317
P577publication date2019-02-04
P1433published inScientific ReportsQ2261792
P1476titleProposed mechanism for the length dependence of the force developed in maximally activated muscles
P478volume9

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cites work (P2860)
Q98386617Increase of resting muscle stiffness, a less considered component of age-related skeletal muscle impairment
Q89604854Overview of the frontiers in multi-scale mechanobiology of muscle and vascular system-Session 1SGA