The Systemic Alterations of Lipids, Alanine-Glucose Cycle and Inter-Organ Amino Acid Metabolism in Swine Model Confirms the Role of Liver in Early Phase of Septic Shock

The Systemic Alterations of Lipids, Alanine-Glucose Cycle and Inter-Organ Amino Acid Metabolism in Swine Model Confirms the Role of Liver in Early Phase of Septic Shock is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FPHYS.2019.00011
P932PMC publication ID6360162
P698PubMed publication ID30745875

P50authorRoberta PastorelliQ106393140
P2093author name stringManuela Ferrario
Fuhong Su
Antoine Herpain
Laura Brunelli
P2860cites workThe Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)Q26768286
Plasma Phospholipid Fatty Acid Profile is Altered in Both Septic and Non-Septic Critically Ill: A Correlation with Inflammatory Markers and Albumin.Q40389776
Alteration of Lysophosphatidylcholine-Related Metabolic Parameters in the Plasma of Mice with Experimental SepsisQ40393439
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Renal haemodynamic response to amino acids infusion in an experimental porcine model of septic shockQ41421451
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Albumin stimulates the release of lysophosphatidylcholine from cultured rat hepatocytesQ42157946
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FOXP3+ regulatory T cells in autoimmune hepatitis are fully functional and not reduced in frequencyQ58130795
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Translational research in the development of novel sepsis therapeutics: logical deductive reasoning or mission impossible?Q83067024
High-volume hemofiltration reduces the expression of myocardial tumor necrosis factor-alpha in septic shock pigsQ85002632
Citrulline a more suitable substrate than arginine to restore NO production and the microcirculation during endotoxemiaQ27302422
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Polymicrobial sepsis is associated with decreased hepatic oxidative phosphorylation and an altered metabolic profileQ33635150
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Lipid metabolites as metabolic messengers in inter-organ communicationQ33831533
Lysophosphatidylcholine enhances the suppressive function of human naturally occurring regulatory T cells through TGF-β productionQ34072401
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Recognition of lysophosphatidylcholine by type II NKT cells and protection from an inflammatory liver diseaseQ34364867
A clinically applicable porcine model of septic and ischemia/reperfusion-induced shock and multiple organ injuryQ34699749
Foxp3 expression in liver correlates with the degree but not the cause of inflammation.Q35104601
Why do animal models (sometimes) fail to mimic human sepsis?Q35760621
Early Fluid Resuscitation and High Volume Hemofiltration Decrease Septic Shock Progression in SwineQ36205712
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Circulating lysophosphatidylcholines are markers of a metabolically benign nonalcoholic fatty liverQ37022557
Advances in sepsis-associated liver dysfunctionQ37233638
Animal models of sepsis: why does preclinical efficacy fail to translate to the clinical setting?Q37356886
Metabolism and atherogenic disease association of lysophosphatidylcholineQ37537825
Albumin as fatty acid transporterQ37595250
The cellular and signaling networks linking the immune system and metabolism in diseaseQ37991199
Hypoalbuminemia.Q38052843
Clinical review: The liver in sepsisQ38058384
Disruption of phospholipid and bile acid homeostasis in mice with nonalcoholic steatohepatitis.Q38328152
Arginine and citrulline and the immune response in sepsis.Q38362838
Lysophosphatidylcholine reduces the organ injury and dysfunction in rodent models of gram-negative and gram-positive shockQ38758160
The past and present of serum aminotransferases and the future of liver injury biomarkers.Q38926316
Cardiopulmonary Arrest and Resuscitation in Severe Sepsis and Septic Shock: A Research Model.Q39098451
Evaluation of a model-based hemodynamic monitoring method in a porcine study of septic shock.Q39711034
Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014.Q40048733
Characterization of a metabolomic profile associated with responsiveness to therapy in the acute phase of septic shock.Q40075609
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectlactateQ349735
septic shockQ1765564
glucoseQ37525
energy metabolismQ30225378
P304page(s)11
P577publication date2019-01-01
P1433published inFrontiers in PhysiologyQ2434141
P1476titleThe Systemic Alterations of Lipids, Alanine-Glucose Cycle and Inter-Organ Amino Acid Metabolism in Swine Model Confirms the Role of Liver in Early Phase of Septic Shock
P478volume10

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cites work (P2860)
Q91871383Lipidomic profile and candidate biomarkers in septic patients
Q98177439Vascular Decoupling in Septic Shock: The Combined Role of Autonomic Nervous System, Arterial Stiffness, and Peripheral Vascular Tone

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