Abstract is: Jeremy Nathans (born July 31, 1958) is a professor of molecular biology and genetics at Johns Hopkins University. He is also a member of the National Academy of Sciences and an investigator of the Howard Hughes Medical Institute. He is known for first isolating and characterizing the opsin genes contributing to human color vision. In 2020 he was awarded the Benjamin Franklin Medal (Franklin Institute) in Life Science. In 2022 he was awarded the Nemmers Prize in Medical Science.
human | Q5 |
P2381 | Academic Tree ID | 12383 |
P646 | Freebase ID | /m/0g9wyjt |
P1960 | Google Scholar author ID | E7kDxi4AAAAJ |
P213 | ISNI | 0000000030585346 |
P244 | Library of Congress authority ID | n88605648 |
P5380 | National Academy of Sciences member ID | 3001705 |
P496 | ORCID iD | 0000-0001-8106-5460 |
P7293 | PLWABN ID | 9810643566605606 |
P3368 | Prabook ID | 444215 |
P4012 | Semantic Scholar author ID | 2170292 |
P214 | VIAF ID | 305146331771718690522 |
P10832 | WorldCat Entities ID | E39PBJmpdQKy4hbVGmvwP7y68C |
P166 | award received | Champalimaud Vision Award | Q1795483 |
William O. Baker Award for Initiatives in Research | Q6952555 | ||
Golden Brain Award | Q17148437 | ||
P184 | doctoral advisor | David Hogness | Q1176459 |
P69 | educated at | Massachusetts Institute of Technology | Q49108 |
Stanford University School of Medicine | Q4115969 | ||
P108 | employer | Johns Hopkins University | Q193727 |
Howard Hughes Medical Institute | Q1512226 | ||
P734 | family name | Nathans | Q36941353 |
Nathans | Q36941353 | ||
Nathans | Q36941353 | ||
P101 | field of work | genetics | Q7162 |
P735 | given name | Jeremy | Q1514341 |
Jeremy | Q1514341 | ||
P463 | member of | National Academy of Sciences | Q270794 |
American Academy of Arts and Sciences | Q463303 | ||
P106 | occupation | geneticist | Q3126128 |
researcher | Q1650915 | ||
P551 | residence | Baltimore | Q5092 |
P21 | sex or gender | male | Q6581097 |
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Q67563336 | Absorption spectra of the hybrid pigments responsible for anomalous color vision |
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Q34233574 | An MRI-based atlas and database of the developing mouse brain |
Q45914648 | An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus. |
Q28511042 | An essential role for frizzled 5 in mammalian ocular development |
Q36401955 | An evolutionary perspective on the photoreceptor damage response. |
Q34306801 | An outer segment localization signal at the C terminus of the photoreceptor-specific retinol dehydrogenase. |
Q28191111 | Anterior-posterior guidance of commissural axons by Wnt-frizzled signaling |
Q46890578 | Axonal growth and guidance defects in Frizzled3 knock-out mice: a comparison of diffusion tensor magnetic resonance imaging, neurofilament staining, and genetically directed cell labeling. |
Q64091463 | Beta-catenin signaling regulates barrier-specific gene expression in circumventricular organ and ocular vasculatures |
Q40279601 | Ca2+-activated Cl- current from human bestrophin-4 in excised membrane patches |
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Q36193045 | Combinatorial expression of Brn3 transcription factors in somatosensory neurons: genetic and morphologic analysis |
Q33687237 | Complete morphologies of basal forebrain cholinergic neurons in the mouse |
Q92023419 | Comprehensive analysis of a mouse model of spontaneous uveoretinitis using single-cell RNA sequencing |
Q91989576 | Defining the binding interface of Amyloid Precursor Protein (APP) and Contactin3 (CNTN3) by site-directed mutagenesis |
Q100755377 | Developmental, cellular, and behavioral phenotypes in a mouse model of congenital hypoplasia of the dentate gyrus |
Q30487495 | Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells |
Q64062101 | Dlg1 activates beta-catenin signaling to regulate retinal angiogenesis and the blood-retina and blood-brain barriers |
Q40275731 | Effects of L1 retrotransposon insertion on transcript processing, localization and accumulation: lessons from the retinal degeneration 7 mouse and implications for the genomic ecology of L1 elements |
Q34003122 | Emergence of novel color vision in mice engineered to express a human cone photopigment |
Q37218588 | Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis |
Q41116966 | Epigenomic Signatures of Neuronal Diversity in the Mammalian Brain |
Q28550899 | Epigenomic landscapes of retinal rods and cones |
Q29568481 | Estrogen-related receptor beta/NR3B2 controls epithelial cell fate and endolymph production by the stria vascularis |
Q34700708 | Expression of the Norrie disease gene (Ndp) in developing and adult mouse eye, ear, and brain |
Q34385622 | Flat mount imaging of mouse skin and its application to the analysis of hair follicle patterning and sensory axon morphology |
Q28586361 | Frizzled 1 and frizzled 2 genes function in palate, ventricular septum and neural tube closure: general implications for tissue fusion processes |
Q39253940 | Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes |
Q28071320 | Frizzled Receptors in Development and Disease |
Q48479704 | Frizzled-3 is required for the development of major fiber tracts in the rostral CNS. |
Q21128778 | Frizzled3 controls axonal development in distinct populations of cranial and spinal motor neurons |
Q24561700 | Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system |
Q28504775 | Frizzled6 controls hair patterning in mice |
Q35637541 | Functional assembly of accessory optic system circuitry critical for compensatory eye movements |
Q80381887 | Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse |
Q34592541 | Genetic mosaic analysis reveals a major role for frizzled 4 and frizzled 8 in controlling ureteric growth in the developing kidney |
Q36161538 | Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision |
Q33396661 | Genetically-directed, cell type-specific sparse labeling for the analysis of neuronal morphology |
Q34469168 | Gpr124 controls CNS angiogenesis and blood-brain barrier integrity by promoting ligand-specific canonical wnt signaling |
Q68053930 | Histidine residues regulate the transition of photoexcited rhodopsin to its active conformation, metarhodopsin II |
Q31065478 | How scientists can reduce their carbon footprint |
Q36696476 | How to draw the line in biomedical research |
Q28316305 | Human rod photoreceptor cGMP-gated channel: amino acid sequence, gene structure, and functional expression |
Q93110741 | Hypoxia tolerance in the Norrin-deficient retina and the chronically hypoxic brain studied at single-cell resolution |
Q28511145 | Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles |
Q64883451 | Interplay of the Norrin and Wnt7a/Wnt7b signaling systems in blood-brain barrier and blood-retina barrier development and maintenance. |
Q48350848 | Intramembrane Proteolysis of Astrotactins. |
Q48396113 | Isolation, sequence analysis, and intron-exon arrangement of the gene encoding bovine rhodopsin |
Q33260025 | Macular degeneration: recent advances and therapeutic opportunities. |
Q64977678 | Molecular determinants in Frizzled, Reck, and Wnt7a for ligand-specific signaling in neurovascular development. |
Q59052444 | Molecular structure of a double helical DNA fragment intercalator complex between deoxy CpG and a terpyridine platinum compound |
Q36474051 | Morphologic diversity of cutaneous sensory afferents revealed by genetically directed sparse labeling |
Q34572398 | Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling |
Q40198640 | Mutational analysis of Norrin-Frizzled4 recognition |
Q30895226 | New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling |
Q28591418 | Norrin, frizzled-4, and Lrp5 signaling in endothelial cells controls a genetic program for retinal vascularization |
Q36502977 | Norrin/Frizzled4 signaling in retinal vascular development and blood brain barrier plasticity |
Q28505895 | Order from disorder: Self-organization in mammalian hair patterning |
Q41839365 | Partial interchangeability of Fz3 and Fz6 in tissue polarity signaling for epithelial orientation and axon growth and guidance |
Q51525316 | Patterning of papillae on the mouse tongue: A system for the quantitative assessment of planar cell polarity signaling. |
Q46267545 | Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium |
Q50787924 | Photobleaching difference absorption spectra of human cone pigments: quantitative analysis and comparison to other methods |
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Q30503853 | Preclinical assessment of CNS drug action using eye movements in mice |
Q40492540 | Proteolytic shedding of the extracellular domain of photoreceptor cadherin. Implications for outer segment assembly |
Q44765735 | Proximal and distal sequences control UV cone pigment gene expression in transgenic zebrafish |
Q45159510 | Quantitative analysis of neuronal morphologies in the mouse retina visualized by using a genetically directed reporter. |
Q43084675 | Rac1 plays an essential role in axon growth and guidance and in neuronal survival in the central and peripheral nervous systems |
Q47958915 | Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation |
Q48132514 | Reck and Gpr124 Are Essential Receptor Cofactors for Wnt7a/Wnt7b-Specific Signaling in Mammalian CNS Angiogenesis and Blood-Brain Barrier Regulation |
Q36673318 | Responses of hair follicle-associated structures to loss of planar cell polarity signaling |
Q34842125 | Retinal function and rhodopsin levels in autosomal dominant retinitis pigmentosa with rhodopsin mutations |
Q24564252 | Rhodopsin mutations in autosomal dominant retinitis pigmentosa |
Q33894818 | Role of a locus control region in the mutually exclusive expression of human red and green cone pigment genes |
Q30445020 | Signaling by sensory receptors |
Q35859036 | Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina |
Q96429621 | Structure of the RECK CC domain, an evolutionary anomaly |
Q24633985 | Structure-function analysis of the bestrophin family of anion channels |
Q24627102 | The Norrin/Frizzled4 signaling pathway in retinal vascular development and disease |
Q46052501 | The evolution of Primate color vision |
Q36944774 | The genomic response of the retinal pigment epithelium to light damage and retinal detachment |
Q28472592 | The optokinetic reflex as a tool for quantitative analyses of nervous system function in mice: application to genetic and drug-induced variation |
Q34382038 | The rod photoreceptor-specific nuclear receptor Nr2e3 represses transcription of multiple cone-specific genes. |
Q28593180 | The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells |
Q34795145 | The role of the hypoxia response in shaping retinal vascular development in the absence of Norrin/Frizzled4 signaling |
Q42362995 | The spatio-temporal domains of Frizzled6 action in planar polarity control of hair follicle orientation |
Q24534058 | The vitelliform macular dystrophy protein defines a new family of chloride channels |
Q35685757 | Tip cell-specific requirement for an atypical Gpr124- and Reck-dependent Wnt/β-catenin pathway during brain angiogenesis |
Q36720615 | Tissue/planar cell polarity in vertebrates: new insights and new questions |
Q58762072 | Transcriptional and epigenomic landscapes of CNS and non-CNS vascular endothelial cells |
Q24318751 | Vascular development in the retina and inner ear: control by Norrin and Frizzled-4, a high-affinity ligand-receptor pair |
Q35306910 | Visual pigments and inherited variation in human vision |
Q42375659 | When whorls collide: the development of hair patterns in frizzled 6 mutant mice |
Q46551569 | Written in our genes? |
Q56594096 | [58] ABCR: Rod photoreceptor-specific ABC transporter responsible for Stargardt disease |
Q1176459 | David Hogness | doctoral student | P185 |
Jeremy Nathans | wikipedia | |
Jeremy Nathans | wikipedia |
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