Local Antigen Encounter Is Essential for Establishing Persistent CD8 T-Cell Memory in the CNS

scientific article published on 04 March 2019

Local Antigen Encounter Is Essential for Establishing Persistent CD8 T-Cell Memory in the CNS is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FIMMU.2019.00351
P932PMC publication ID6409353
P698PubMed publication ID30886617

P50authorAllan Randrup ThomsenQ30127185
Loulieta NazeraiQ56323257
Jan Pravsgaard ChristensenQ43182017
P2093author name stringAmalie S Schøller
Masja Fonnes
P2860cites workSkin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunityQ24604251
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Infection as an Environmental Trigger of Multiple Sclerosis Disease ExacerbationQ26779416
Tissue-resident memory T cellsQ26829804
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One-pot, mix-and-read peptide-MHC tetramersQ28472228
Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycinQ28507393
Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasisQ28589263
Central memory and effector memory T cell subsets: function, generation, and maintenanceQ29615097
Virus-specific and bystander CD8 T cells recruited during virus-induced encephalomyelitisQ33724194
Local Inflammatory Cues Regulate Differentiation and Persistence of CD8+ Tissue-Resident Memory T CellsQ33728531
Dynamic T cell migration program provides resident memory within intestinal epitheliumQ33730150
Adenovirus infections in immunocompetent and immunocompromised patientsQ34057627
Glial cells suppress postencephalitic CD8+ T lymphocytes through PD-L1.Q34076317
Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residenceQ34241501
CD4+ T cell help guides formation of CD103+ lung-resident memory CD8+ T cells during influenza viral infectionQ35073840
Proinflammatory microenvironments within the intestine regulate the differentiation of tissue-resident CD8⁺ T cells responding to infectionQ35202406
Quantifying Memory CD8 T Cells Reveals Regionalization of ImmunosurveillanceQ35591980
The immunogenicity of intracerebral virus infection depends on anatomical site.Q35874762
Long-lived epithelial immunity by tissue-resident memory T (TRM) cells in the absence of persisting local antigen presentation.Q35935558
Antigen-independent differentiation and maintenance of effector-like resident memory T cells in tissuesQ35936035
Adenoviral vectors persist in vivo and maintain activated CD8+ T cells: implications for their use as vaccines.Q35990696
Cutting Edge: Resident Memory CD8 T Cells Express High-Affinity TCRsQ36119414
Intracerebral injections and the growth of viruses in the mouse brainQ36152155
The emerging role of resident memory T cells in protective immunity and inflammatory diseaseQ36267804
Immediate cytotoxicity but not degranulation distinguishes effector and memory subsets of CD8+ T cellsQ36399420
A vaccine strategy that protects against genital herpes by establishing local memory T cellsQ36403540
Combined local and systemic immunization is essential for durable T-cell mediated heterosubtypic immunity against influenza A virusQ36527796
Local antigen in nonlymphoid tissue promotes resident memory CD8+ T cell formation during viral infectionQ36949921
Brain-resident memory T cells represent an autonomous cytotoxic barrier to viral infectionQ37179031
Lymphocytic choriomeningitis virus-induced central nervous system disease: a model for studying the role of chemokines in regulating the acute antiviral CD8+ T-cell response in an immune-privileged organQ37267001
Persistence of transgene expression influences CD8+ T-cell expansion and maintenance following immunization with recombinant adenovirusQ37452136
CD8(+) T lymphocyte mobilization to virus-infected tissue requires CD4(+) T-cell helpQ37461871
Antigen-dependent competition shapes the local repertoire of tissue-resident memory CD8+ T cellsQ37500355
Specific niches for lung-resident memory CD8+ T cells at the site of tissue regeneration enable CD69-independent maintenance.Q37500370
Brain-resident memory CD8+ T cells induced by congenital CMV infection prevent brain pathology and virus reactivation.Q50532976
The CD8+ T cell population elicited by recombinant adenovirus displays a novel partially exhausted phenotype associated with prolonged antigen presentation that nonetheless provides long-term immunity.Q51986133
Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.Q52040367
Tissue-resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance.Q54234126
MHC Class II-Associated Invariant Chain Linkage of Antigen Dramatically Improves Cell-Mediated Immunity Induced by Adenovirus VaccinesQ56798214
The role of CC chemokine receptor 5 in antiviral immunityQ56798219
Pathogenic role of tissue-resident memory T cells in autoimmune diseasesQ60355860
New insights on adenovirus as vaccine vectorsQ37513550
Cutting edge: resident memory CD8 T cells occupy frontline niches in secondary lymphoid organsQ37662759
Dissection of an inflammatory process induced by CD8+ T cellsQ37812033
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Tissue resident memory T cells and viral immunityQ39042003
Immunodominance in virus-induced CD8(+) T-cell responses is dramatically modified by DNA immunization and is regulated by gamma interferonQ39752873
T-Cell-Mediated Immunopathology in Viral InfectionsQ39943334
Resident memory T cells in the skin mediate durable immunity to melanoma.Q40122403
Cutting edge: CD69 interference with sphingosine-1-phosphate receptor function regulates peripheral T cell retentionQ41520161
CD4 helpers put tissue-resident memory cells in their placeQ41678617
Quantification of lymphocytic choriomeningitis virus with an immunological focus assay in 24- or 96-well platesQ41681194
The developmental pathway for CD103(+)CD8+ tissue-resident memory T cells of skin.Q42259563
Cutting edge: intravascular staining redefines lung CD8 T cell responses.Q42324066
Thymus-resident memory CD8+ T cells mediate local immunity.Q43427766
IFN-gamma-induced chemokines synergize with pertussis toxin to promote T cell entry to the central nervous system.Q43471572
Vaccination against lymphocytic choriomeningitis virus infection in MHC class II-deficient miceQ43693190
IFN-gamma and CD8+ T cells restore host defenses against Pneumocystis carinii in mice depleted of CD4+ T cellsQ44825785
Memory T cells in nonlymphoid tissue that provide enhanced local immunity during infection with herpes simplex virusQ45385806
Replication-incompetent adenoviral vaccine vector elicits effective anti-immunodeficiency-virus immunityQ45734062
Virus dissemination through the brain parenchyma without immunologic controlQ45761170
Virus-induced polyclonal T cell activation is followed by apoptosis: partitioning of CD8+ T cells based on alpha 4 integrin expressionQ45770080
Meta-analysis of the Age-Dependent Efficacy of Multiple Sclerosis TreatmentsQ47200732
Role of interferon-gamma in the pathogenesis of LCMV-induced meningitis: unimpaired leucocyte recruitment, but deficient macrophage activation in interferon-gamma knock-out miceQ47848881
Evidence that a significant number of naive T cells enter non-lymphoid organs as part of a normal migratory pathwayQ48534206
Recruitment, activation and proliferation of CD8+ memory T cells in an immunoprivileged site.Q48535536
Pulmonary antigen encounter regulates the establishment of tissue-resident CD8 memory T cells in the lung airways and parenchyma.Q49912409
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectCNSQ227890
P304page(s)351
P577publication date2019-03-04
P1433published inFrontiers in ImmunologyQ27723748
P1476titleLocal Antigen Encounter Is Essential for Establishing Persistent CD8+ T-Cell Memory in the CNS
P478volume10

Reverse relations

cites work (P2860)
Q90167845Disruption of cellular proteostasis by H1N1 influenza A virus causes α-synuclein aggregation
Q89920495Memory CD4+ T Cells in Immunity and Autoimmune Diseases

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