Bruno O Villoutreix

researcher

Bruno O Villoutreix is …
instance of (P31):
humanQ5

External links are
P2456DBLP author ID69/3926
P496ORCID iD0000-0002-6456-7730

P108employerFrench National Institute of Health and Medical ResearchQ1474517
P735given nameBrunoQ1874605
BrunoQ1874605
P106occupationresearcherQ1650915
P21sex or gendermaleQ6581097

Reverse relations

author (P50)
Q38758481A Cell-Penetrating Peptide Targeting AAC-11 Specifically Induces Cancer Cells Death.
Q40343332A formylated hexapeptide ligand mimics the ability of Wnt-5a to impair migration of human breast epithelial cells
Q112643710A new ChEMBL dataset for the similarity-based target fishing engine FastTargetPred: Annotation of an exhaustive list of linear tetrapeptides
Q33379337A novel non-synonymous polymorphism (p.Arg240His) in C4b-binding protein is associated with atypical hemolytic uremic syndrome and leads to impaired alternative pathway cofactor activity
Q41511323AMMOS2: a web server for protein-ligand-water complexes refinement via molecular mechanics
Q28474233AMMOS: Automated Molecular Mechanics Optimization tool for in silico Screening
Q48876534Acute genetic ablation of pendrin lowers blood pressure in mice.
Q40138033Aggrecanase-2 inhibitors based on the acylthiosemicarbazide zinc-binding group
Q46815143An exploration of the 3D chemical space has highlighted a specific shape profile for the compounds intended to inhibit protein-protein interactions.
Q24645042Analysis of binding sites on complement factor I that are required for its activity
Q42141370Analysis of binding sites on complement factor I using artificial N-linked glycosylation
Q89874776Analysis of protein missense alterations by combining sequence- and structure-based methods
Q93345979Analysis of solvent-exposed and buried co-crystallized ligands: a case study to support the design of novel protein-protein interaction inhibitors
Q89601782Anti-Factor B Antibodies and Acute Postinfectious GN in Children
Q37705854Blockade of the malignant phenotype by β-subunit selective noncovalent inhibition of immuno- and constitutive proteasomes.
Q48539615Breast cancer targeting through inhibition of the endoplasmic reticulum-based apoptosis regulator Nrh/BCL2L10.
Q60250460Characterization of the complement inhibitory function of Rhesus rhadinovirus
Q40029426Characterization of the complement inhibitory function of rhesus rhadinovirus complement control protein (RCP).
Q27010681Chemical libraries dedicated to protein-protein interactions
Q35741515Complement inhibitor C4b-binding protein-friend or foe in the innate immune system?
Q38950578Computational Biology and Chemistry in MTi: Emphasis on the Prediction of Some ADMET Properties.
Q38732067Computational analysis of calculated physicochemical and ADMET properties of protein-protein interaction inhibitors
Q38377610Computational investigations of hERG channel blockers: New insights and current predictive models
Q30884784DG-AMMOS: a new tool to generate 3d conformation of small molecules using distance geometry and automated molecular mechanics optimization for in silico screening
Q38908172DNA damage-induced nuclear translocation of Apaf-1 is mediated by nucleoporin Nup107.
Q35921636Design of protein membrane interaction inhibitors by virtual ligand screening, proof of concept with the C2 domain of factor V
Q28473098Designing focused chemical libraries enriched in protein-protein interaction inhibitors using machine-learning methods
Q33408602Development of novel thiazolopyrimidines as CDC25B phosphatase inhibitors
Q38884302Discoidin Domains as Emerging Therapeutic Targets.
Q52651324Discovery of novel inhibitors of vascular endothelial growth factor-A-Neuropilin-1 interaction by structure-based virtual screening.
Q33649365Druggable pockets and binding site centric chemical space: a paradigm shift in drug discovery
Q48159506Expression and functional characterization of two natural heparin-binding site variants of antithrombin.
Q33371792FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects
Q35604907FAF-Drugs3: a web server for compound property calculation and chemical library design.
Q47317732FAF-Drugs4: free ADME-tox filtering computations for chemical biology and early stages drug discovery
Q98391929Fast Rescoring Protocols to Improve the Performance of Structure-Based Virtual Screening Performed on Protein-Protein Interfaces
Q34662757Free resources to assist structure-based virtual ligand screening experiments
Q33420841Functional characterization of two novel non-synonymous alterations in CD46 and a Q950H change in factor H found in atypical hemolytic uremic syndrome patients
Q35793072Functions of human complement inhibitor C4b-binding protein in relation to its structure
Q36546628Genetic polymorphisms associated with increased risk of developing chronic myelogenous leukemia
Q28303343Genetic, molecular and functional analyses of complement factor I deficiency
Q89800911Gly197Arg mutation in protein C causes recurrent thrombosis in a heterozygous carrier
Q35037859Identification by in silico and in vitro screenings of small organic molecules acting as reversible inhibitors of kallikreins
Q35165195Identification of Small Inhibitory Molecules Targeting the Bfl-1 Anti-Apoptotic Protein That Alleviates Resistance to ABT-737.
Q47161167Identification of insulin-sensitizing molecules acting by disrupting the interaction between the Insulin Receptor and Grb14.
Q35090048Identification of novel small molecule inhibitors of activated protein C.
Q35573183In silico design of low molecular weight protein-protein interaction inhibitors: Overall concept and recent advances
Q28536904In silico mechanistic profiling to probe small molecule binding to sulfotransferases
Q41243043In silico model of the human ClC-Kb chloride channel: pore mapping, biostructural pathology and drug screening
Q37677338In silico studies of blood coagulation proteins: from mosaic proteases to nonenzymatic cofactor inhibitors
Q37130829In silico-in vitro screening of protein-protein interactions: towards the next generation of therapeutics
Q28534051Insights into an original pocket-ligand pair classification: a promising tool for ligand profile prediction
Q55421031Insights into molecular mechanisms of drug metabolism dysfunction of human CYP2C9*30.
Q30378479Integrated structure- and ligand-based in silico approach to predict inhibition of cytochrome P450 2D6.
Q36564330Kaposi's sarcoma-associated herpes virus complement control protein: KCP--complement inhibition and more
Q27690213Ligand efficiency driven design of new inhibitors of Mycobacterium tuberculosis transcriptional repressor EthR using fragment growing, merging, and linking approaches
Q33385907MED-3DMC: a new tool to generate 3D conformation ensembles of small molecules with a Monte Carlo sampling of the conformational space
Q33283556MED-SuMoLig: a new ligand-based screening tool for efficient scaffold hopping
Q33327574MS-DOCK: accurate multiple conformation generator and rigid docking protocol for multi-step virtual ligand screening
Q35597960MTiOpenScreen: a web server for structure-based virtual screening.
Q113308777Machine learning-driven identification of drugs inhibiting cytochrome P450 2C9
Q40422254Mapping of the factor Xa binding site on factor Va by site-directed mutagenesis
Q44534312Mutations in alpha-chain of C4BP that selectively affect its factor I cofactor function
Q28263131Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I
Q28267924Mutations in components of complement influence the outcome of Factor I-associated atypical hemolytic uremic syndrome
Q28167994Mutations within the cyclooxygenase-1 gene in aspirin non-responders with recurrence of stroke
Q38119805One hundred thousand mouse clicks down the road: selected online resources supporting drug discovery collected over a decade
Q24812137PCE: web tools to compute protein continuum electrostatics
Q88446699Pan-assay interference compounds (PAINS) that may not be too painful for chemical biology projects
Q38969903Pharmacogenomics of the cytochrome P450 2C family: impacts of amino acid variations on drug metabolism.
Q79100949Probing plasma clearance of the thrombin–antithrombin complex with a monoclonal antibody against the putative serpin–enzyme complex receptor‐binding site
Q28293819Proposed structural models of the prothrombinase (FXa-FVa) complex
Q30368994Protein structure analysis online.
Q30962611Rationalizing the chemical space of protein-protein interaction inhibitors
Q33262082Receptor-based computational screening of compound databases: the main docking-scoring engines
Q36110345Regulation of blood coagulation by the protein C anticoagulant pathway: novel insights into structure-function relationships and molecular recognition
Q90858094Rigorous sampling of docking poses unveils binding hypothesis for the halogenated ligands of L-type Amino acid Transporter 1 (LAT1)
Q60250710Role of CCP2 of the C4b-binding protein β-chain in protein S binding evaluated by mutagenesis and monoclonal antibodies
Q36944104Screening Outside the Catalytic Site: Inhibition of Macromolecular Inter-actions Through Structure-Based Virtual Ligand Screening Experiments.
Q34790625Structural bioinformatics: methods, concepts and applications to blood coagulation proteins.
Q56895697Structural requirements of anticoagulant protein S for its binding to the complement regulator C4b-binding protein
Q36526549Structural stability and heat-induced conformational change of two complement inhibitors: C4b-binding protein and factor H
Q98171425Structure-based drug repositioning over the human TMPRSS2 protease domain: search for chemical probes able to repress SARS-CoV-2 Spike protein cleavages
Q33285015Structure-based virtual ligand screening with LigandFit: pose prediction and enrichment of compound collections
Q37660412Structure-based virtual ligand screening: recent success stories
Q34111157Targeting the proangiogenic VEGF-VEGFR protein-protein interface with drug-like compounds by in silico and in vitro screening
Q39672653Tensin2 reduces intracellular phosphatidylinositol 3,4,5-trisphosphate levels at the plasma membrane
Q33920633The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections
Q51810670The Kaposi's sarcoma-associated herpesvirus complement control protein (KCP) binds to heparin and cell surfaces via positively charged amino acids in CCP1-2.
Q45013859The Kaposi's sarcoma-associated herpesvirus complement control protein mimics human molecular mechanisms for inhibition of the complement system
Q38287370The N-terminal epidermal growth factor-like domain of coagulation factor IX. Probing its functions in the activation of factor IX and factor X with a monoclonal antibody
Q36156027The anticoagulant protein C pathway
Q35462720Theileria parasites secrete a prolyl isomerase to maintain host leukocyte transformation
Q35620775Therapeutic Targeting of Nuclear γ-Tubulin in RB1-Negative Tumors.
Q37953143Toward in silico structure-based ADMET prediction in drug discovery.
Q28478649Tyrosine kinase syk non-enzymatic inhibitors and potential anti-allergic drug-like compounds discovered by virtual and in vitro screening
Q90428394Virtual screening web servers: designing chemical probes and drug candidates in the cyberspace
Q33631088Zebrafish ProVEGF-C expression, proteolytic processing and inhibitory effect of unprocessed ProVEGF-C during fin regeneration
Q38108039iPPI-DB: a manually curated and interactive database of small non-peptide inhibitors of protein-protein interactions
Q36435078iPPI-DB: an online database of modulators of protein-protein interactions.

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