Abstract is: Kenneth S. Kosik, M.D. is an American neurologist, author, researcher and professor in neuroscience at the University of California, Santa Barbara. Recent contributions includes a significant discovery in understanding the way human embryonic stem cells function. He has contributed to novel thinking about how to reduce risk for getting Alzheimer's disease and reduce the impact of this illness on our communities. He was the founder and executive director of Cognitive Fitness & Innovative Therapies, followed by the Cottage Center for Brain Fitness. Kosik provided much of the original data on the largest family in the world with a genetic form of Alzheimer's disease located in Antioquia, Colombia.
| human | Q5 |
| P11496 | CiNii Research ID | 1140845216617452544 |
| P6178 | Dimensions author ID | 01103553121.81 |
| P646 | Freebase ID | /m/076yhcb |
| P227 | GND ID | 122505219X |
| P269 | IdRef ID | 059892420 |
| P213 | ISNI | 0000000083960824 |
| P244 | Library of Congress authority ID | n94803476 |
| P271 | NACSIS-CAT author ID | DA09011072 |
| P349 | NDL Authority ID | 00996393 |
| P691 | NL CR AUT ID | xx0208188 |
| P1015 | NORAF ID | 90886621 |
| P856 | official website | https://labs.mcdb.ucsb.edu/kosik/kenneth/ |
| P496 | ORCID iD | 0000-0003-3224-5179 |
| P214 | VIAF ID | 77034530 |
| P10832 | WorldCat Entities ID | E39PBJpYrt4DVbVKfWDGjMXGHC |
| P166 | award received | Fellow of the American Association for the Advancement of Science | Q5442484 |
| P1343 | described by source | Medvik | Q99413897 |
| P69 | educated at | Drexel University | Q603034 |
| P108 | employer | Harvard University | Q13371 |
| University of California, Santa Barbara | Q263064 | ||
| P734 | family name | Kosik | Q37270657 |
| Kosik | Q37270657 | ||
| Kosik | Q37270657 | ||
| P101 | field of work | medicine | Q11190 |
| neurology | Q83042 | ||
| P735 | given name | Kenneth | Q2492643 |
| Kenneth | Q2492643 | ||
| P1412 | languages spoken, written or signed | English | Q1860 |
| P106 | occupation | scientist | Q901 |
| neurologist | Q783906 | ||
| P5008 | on focus list of Wikimedia project | WikiProject COVID-19 | Q87748614 |
| P21 | sex or gender | male | Q6581097 |
| Q121988855 | Jak přelstít Alzheimera: co můžete udělat, abyste snížili riziko této nemoci |
| Q90829009 | A Comprehensive Resource for Induced Pluripotent Stem Cells from Patients with Primary Tauopathies |
| Q104134667 | A Fast and Accessible Method for the Isolation of RNA, DNA, and Protein to Facilitate the Detection of SARS-CoV-2 |
| Q42049255 | A Primate lncRNA Mediates Notch Signaling during Neuronal Development by Sequestering miRNA |
| Q95604881 | A Scalable, Easy-to-Deploy, Protocol for Cas13-Based Detection of SARS-CoV-2 Genetic Material |
| Q39293075 | A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation |
| Q46352528 | A delta-catenin signaling pathway leading to dendritic protrusions |
| Q92657920 | A farnesyltransferase inhibitor activates lysosomes and reduces tau pathology in mice with tauopathy |
| Q29618667 | A microRNA array reveals extensive regulation of microRNAs during brain development |
| Q46171939 | A microRNA-mRNA expression network during oral siphon regeneration in Ciona. |
| Q45952373 | A molecular signature for anastasis, recovery from the brink of apoptotic cell death. |
| Q21092252 | A post-synaptic scaffold at the origin of the animal kingdom |
| Q34775670 | A quantitative framework to evaluate modeling of cortical development by neural stem cells |
| Q88328815 | Action potential propagation recorded from single axonal arbors using multielectrode arrays |
| Q28584311 | Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species |
| Q34039983 | Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments |
| Q53255736 | Apolipoprotein Eepsilon4 modifies Alzheimer's disease onset in an E280A PS1 kindred. |
| Q34521275 | Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats |
| Q44643912 | BACE1 Suppression by RNA Interference in Primary Cortical Neurons |
| Q59030207 | Better read than dread |
| Q35075754 | Beyond phrenology, at last |
| Q40590079 | Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival |
| Q34274231 | Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study |
| Q46460917 | CADASIL mutations impair Notch3 glycosylation by Fringe |
| Q28183470 | CHIP-Hsc70 Complex Ubiquitinates Phosphorylated Tau and Enhances Cell Survival |
| Q98614852 | COVID-19 in older people with cognitive impairment in Latin America |
| Q90621029 | Cell biology in support of neurological research: 2018 highlights |
| Q90411704 | Cofactors are essential constituents of stable and seeding-active tau fibrils |
| Q90305528 | Control over single-cell distribution of G1 lengths by WNT governs pluripotency |
| Q36106887 | Deep annotation of mouse iso-miR and iso-moR variation |
| Q46614986 | Defining Cdk5 ligand chemical space with small molecule inhibitors of tau phosphorylation. |
| Q28283216 | Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction |
| Q36064214 | Delta-catenin at the synaptic-adherens junction |
| Q35950909 | Detection of Prokaryotic Genes in the Amphimedon queenslandica Genome |
| Q33295390 | Detection of a microRNA signal in an in vivo expression set of mRNAs |
| Q45240413 | Development of a fluorescent high throughput assay for tau aggregation |
| Q44789917 | Development of an assay to screen for inhibitors of tau phosphorylation by cdk5. |
| Q43247094 | Developmental attenuation of N-methyl-D-aspartate receptor subunit expression by microRNAs |
| Q37048487 | Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models |
| Q35050279 | Discovery of compounds that will prevent tau pathology |
| Q45160368 | Diseases: Study neuron networks to tackle Alzheimer's |
| Q79358678 | Distribution pattern of Notch3 mutations suggests a gain-of-function mechanism for CADASIL |
| Q24675757 | Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho. |
| Q112706976 | Dynamic assembly of the mRNA m6A methyltransferase complex is regulated by METTL3 phase separation |
| Q38399425 | Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury |
| Q88267032 | Evolution of New miRNAs and Cerebro-Cortical Development |
| Q24338463 | Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains |
| Q34350733 | Exploratory data from complete genomes of familial alzheimer disease age-at-onset outliers |
| Q37339477 | Exploring the early origins of the synapse by comparative genomics |
| Q41993280 | FLEXITau: Quantifying Post-translational Modifications of Tau Protein in Vitro and in Human Disease |
| Q30529034 | Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study |
| Q30519460 | Functionalization of a protosynaptic gene expression network |
| Q45138638 | Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau. |
| Q37360904 | Genetic correction of tauopathy phenotypes in neurons derived from human induced pluripotent stem cells |
| Q91466047 | Genetic origin of a large family with a novel PSEN1 mutation (Ile416Thr) |
| Q53295556 | Genetic testing must recognize impact of bad news on recipient. |
| Q36021547 | Genomic DISC1 Disruption in hiPSCs Alters Wnt Signaling and Neural Cell Fate |
| Q34497106 | Growth hormone is produced within the hippocampus where it responds to age, sex, and stress |
| Q46069709 | Haploinsufficiency of BAZ1B contributes to Williams syndrome through transcriptional dysregulation of neurodevelopmental pathways. |
| Q45942304 | Heterogeneous dysregulation of microRNAs across the autism spectrum. |
| Q41842411 | Highly conserved O-fucose sites have distinct effects on Notch1 function |
| Q35106511 | Homozygosity of the autosomal dominant Alzheimer disease presenilin 1 E280A mutation |
| Q41151197 | Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability |
| Q112649895 | Human neural tube morphogenesis in vitro by geometric constraints |
| Q24630366 | Identification of many microRNAs that copurify with polyribosomes in mammalian neurons |
| Q34985817 | Identification of piRNAs in the central nervous system. |
| Q92970882 | In vitro validation of in silico identified inhibitory interactions |
| Q91971770 | LRP1 is a master regulator of tau uptake and spread |
| Q39051422 | Life at Low Copy Number: How Dendrites Manage with So Few mRNAs |
| Q104078709 | Liquid-liquid phase separation of tau driven by hydrophobic interaction facilitates fibrillization of tau |
| Q34159111 | Long- and short-term CDK5 knockdown prevents spatial memory dysfunction and tau pathology of triple transgenic Alzheimer's mice |
| Q37085329 | MCP-1 and eotaxin-1 selectively and negatively associate with memory in MCI and Alzheimer's disease dementia phenotypes |
| Q50099343 | MEA Viewer: A high-performance interactive application for visualizing electrophysiological data |
| Q28117661 | MOV10 and FMRP regulate AGO2 association with microRNA recognition elements |
| Q34036067 | MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state |
| Q21562511 | MUC1* mediates the growth of human pluripotent stem cells |
| Q33565018 | Mechanisms of age-related cognitive change and targets for intervention: epigenetics. |
| Q24811302 | MicroRNA profiling of the murine hematopoietic system |
| Q39626643 | MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states |
| Q37808577 | MicroRNA regulation of neural stem cells and neurogenesis |
| Q46202742 | MicroRNA-124: micromanager of neurogenesis |
| Q24320635 | MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells |
| Q28262214 | MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells |
| Q34842477 | MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells |
| Q46084261 | MicroRNAs and Cellular Phenotypy |
| Q37633028 | MicroRNAs potentiate neural development |
| Q44592221 | MicroRNAs tell an evo-devo story |
| Q33346479 | MicroRNAs: regulators of oncogenesis and stemness |
| Q92229463 | Microglial microRNAs mediate sex-specific responses to tau pathology |
| Q45414718 | Molecular biology: Circles reshape the RNA world |
| Q34023915 | NMDA mediated contextual conditioning changes miRNA expression |
| Q64071268 | Narrow equilibrium window for complex coacervation of tau and RNA under cellular conditions |
| Q53262364 | Neuroscience gears up for duel on the issue of brain versus deity. |
| Q33316520 | New approaches to the discovery of cdk5 inhibitors |
| Q92471568 | Non-contact monitoring of extra-cellular field potentials with a multi-electrode array |
| Q37321828 | Noncoding RNAs in Long-Term Memory Formation |
| Q33609404 | Novel primate miRNAs coevolved with ancient target genes in germinal zone-specific expression patterns |
| Q28394410 | Nrf2, a regulator of the proteasome, controls self-renewal and pluripotency in human embryonic stem cells |
| Q28302044 | Origin of the PSEN1 E280A mutation causing early-onset Alzheimer's disease |
| Q39173518 | Parallel discovery of Alzheimer's therapeutics |
| Q35748069 | Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies |
| Q33786340 | Particle display: a quantitative screening method for generating high-affinity aptamers. |
| Q90201546 | Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis |
| Q46192661 | Personalized medicine for effective Alzheimer disease treatment |
| Q43833323 | PhDs: what's left if science abdicates? |
| Q35992172 | Phosphorylated tau and the neurodegenerative foldopathies |
| Q57660755 | Postsynaptic Element Contributes to the Delay in Synaptogenesis in Synapsin I-Deficient Neurons |
| Q46139377 | Primary Cilium-Autophagy-Nrf2 (PAN) Axis Activation Commits Human Embryonic Stem Cells to a Neuroectoderm Fate. |
| Q33879490 | RNA stores tau reversibly in complex coacervates |
| Q34154748 | RNAi functions in cultured mammalian neurons |
| Q43982119 | Reconstructing ancestral genome content based on symmetrical best alignments and Dollo parsimony |
| Q39752614 | Regulation of AMPA receptor trafficking by delta-catenin. |
| Q93223327 | Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development |
| Q78878862 | Resistance to autosomal dominant Alzheimer’s disease in an APOE3 Christchurch homozygote: a case report |
| Q35690385 | Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS |
| Q89381153 | Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS |
| Q34736851 | SMN regulates axonal local translation via miR-183/mTOR pathway |
| Q24628256 | Silencing of CDK5 reduces neurofibrillary tangles in transgenic alzheimer's mice |
| Q35902026 | Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR. |
| Q42687919 | Spatial learning and memory is preserved in rats after early development in a microgravity environment |
| Q37020782 | Specific microRNAs modulate embryonic stem cell-derived neurogenesis. |
| Q39958205 | Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing |
| Q33742151 | Staged miRNA re-regulation patterns during reprogramming |
| Q31140540 | Statistical analysis of dendritic spine distributions in rat hippocampal cultures |
| Q34706737 | Structure-activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors |
| Q41534293 | Synaptic dysregulation in a human iPS cell model of mental disorders |
| Q34932548 | Synaptic tagging -- who's it? |
| Q45012796 | Tamoxifen inhibits CDK5 kinase activity by interacting with p35/p25 and modulates the pattern of tau phosphorylation. |
| Q89871503 | Tau Condensates |
| Q55023550 | Tau Internalization is Regulated by 6-O Sulfation on Heparan Sulfate Proteoglycans (HSPGs). |
| Q102059679 | Tau PTM Profiles Identify Patient Heterogeneity and Stages of Alzheimer's Disease |
| Q46828505 | Tau immunization: a cautionary tale? |
| Q42582536 | Tau-er of Power |
| Q46693727 | Teaching resources. A model for local regulation of translation near active synapses |
| Q22122176 | The Amphimedon queenslandica genome and the evolution of animal complexity |
| Q36255488 | The Elegance of the MicroRNAs: A Neuronal Perspective |
| Q28217069 | The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF |
| Q42656948 | The Role of Chromatin Density in Cell Population Heterogeneity during Stem Cell Differentiation |
| Q37401466 | The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule. |
| Q28570538 | The mammalian RNA-binding protein Staufen2 links nuclear and cytoplasmic RNA processing pathways in neurons |
| Q34585692 | The message and the messenger: delivering RNA in neurons |
| Q36657801 | The neuronal microRNA system |
| Q38361201 | The outer subventricular zone and primate-specific cortical complexification. |
| Q100391749 | The proline-rich domain promotes Tau liquid-liquid phase separation in cells |
| Q46110730 | Tracking Down Mutations Cell by Cell |
| Q36029971 | Transcriptional profiling reveals regulated genes in the hippocampus during memory formation. |
| Q34286270 | Transcriptome profiling of the demosponge Amphimedon queenslandica reveals genome-wide events that accompany major life cycle transitions |
| Q30356300 | Traveling the tau pathway: a personal account. |
| Q37316511 | Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease |
| Q33750129 | Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology |
| Q44944491 | Wnt-1 expression in PC12 cells induces exon 15 deletion and expression of L-APP. |
| Q36959034 | f-divergence cutoff index to simultaneously identify differential expression in the integrated transcriptome and proteome |
| Q92573558 | iPSCs-derived nerve-like cells from familial Alzheimer's disease PSEN 1 E280A reveal increased amyloid-beta levels and loss of the Y chromosome |
| Q46043945 | iPhemap: an atlas of phenotype to genotype relationships of human iPSC models of neurological diseases |
| Q40969425 | β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice |
| Kenneth S. Kosik | wikipedia |
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